PCSF: TCGA vs GTEx

Description

Healthy ovarian cell RNA-seq data was downloaded from GTEx and differential expression was performed comparing it with data from the TCGA-OV project.

Step 1: Query the TCGA database and obtain TCGA-OV project data. Also load GTEx data

Show code

# query TCGA for TCGA-OV project data
query_TCGA <- GDCquery(project = "TCGA-OV",
                      experimental.strategy = "RNA-Seq",
                      data.category = "Transcriptome Profiling",
                      data.type = "Gene Expression Quantification",
                      access = "open")

output_query_TCGA <- getResults(query_TCGA)

# check sample types
table(output_query_TCGA$sample_type)


# get clinical data
clinical_query_TCGA_OV <- GDCquery_clinic(project = "TCGA-OV",
                                          type = "clinical")

TCGA_OV_clinical_data <- subset(clinical_query_TCGA_OV, select = c("project", "submitter_id", "figo_stage", "tissue_or_organ_of_origin"))


# combine stage ID with sample info
master_df <- merge(TCGA_OV_clinical_data, output_query_TCGA, by.x = "submitter_id", by.y = "cases.submitter_id")
master_df <- subset(master_df, select = c("project.x", "figo_stage", "cases", "file_name", "sample_type", "tissue_or_organ_of_origin"))
colnames(master_df)[6] <- "primary_site"

# check number of stages included
table(master_df$figo_stage, useNA = "always")

# download and prepare TCGA-OV project data
GDCdownload(query_TCGA, directory = "no_gepia/")

TCGA_OV_data <- GDCprepare(query_TCGA, summarizedExperiment = TRUE, directory = "no_gepia/")
TCGA_OV_data_unstranded <- assay(TCGA_OV_data, "unstranded")

# format rownames
rownames(TCGA_OV_data_unstranded) <- gsub("\\.\\d+", "", rownames(TCGA_OV_data_unstranded))
TCGA_OV_data_unstranded <- as.data.frame(TCGA_OV_data_unstranded)

# load GTEx data
GTEx_raw <- read.table("no_gepia/gene_reads_2017-06-05_v8_ovary.gct", skip = 2, header = T)

# format to match TCGA data
GTEx_data <- GTEx_raw[, -c(1:3)]
rownames(GTEx_data) <- GTEx_raw$Name
rownames(GTEx_data) <- gsub("\\.\\d+", "", rownames(GTEx_data))

save(TCGA_OV_data_unstranded, GTEx_data, file = "no_gepia/TCGA_OV_data_unstranded.RData")

Step 2: Subset non-active genes across all samples

##    Mode   FALSE    TRUE 
## logical   40250   15410

Step 3: Differential expression analysis using edgeR

## Disp = 0.39268 , BCV = 0.6266

##        groupcancer
## Down          1211
## NotSig       12153
## Up            2046

Step 4: PCSF file prep - Create score file and format STRING interaction data

• Convert gene ensembl to gene symbol

• Create score file from logFC values

• Feed list of proteins into STRING/Cytoscape

• Format output and create interaction file

Show code + removed genes

# read in the data
data <- read.csv("no_gepia/edgeR_dif_exp_genes.csv")

# subset the gene_id and logFC columns
data <- subset(data, select = c("gene_id", "logFC"))

# convert to gene symbol
uniprot_id <- getBM(attributes = c("ensembl_gene_id", "external_gene_name"), 
                       filters = "ensembl_gene_id", 
                       values = data$gene_id, 
                       mart = ensembl)

# remove empty rows
uniprot_id <- subset(uniprot_id, external_gene_name != "")

# check for duplicate uniprot ids
uniprot_id <- distinct(uniprot_id)

# merge back with original data
colnames(uniprot_id)[1] <- "gene_id"

uniprot_data <- merge(uniprot_id, data, by = "gene_id")

uniprot_data <- subset(uniprot_data, select = c("external_gene_name", "logFC"))

# check to see if genes that at all genes were converted at least once
missing_genes <- anti_join(data, uniprot_id, by = "gene_id")

# create score file
#write.csv(uniprot_data, "no_gepia/pcsf_score.csv")

## create ensemble protein list for interaction db
#write.table(uniprot_data$external_gene_name, "no_gepia/gene_list.txt", row.names = F, col.names = F, quote = F)

Step 5: Run PCSF and create cross reference results with AF structures for durggability

##   52.31% of your terminal nodes are included in the interactome
##   Solving the PCSF by adding random noise to the edge costs...

## Time difference of 39.39194 secs

Note: The citation scores for this data were generated outside this R script using PubMed API

Show raw table

PCSF Druggability Results

external_gene_name	uniprot_gn_id	cluster	betweenness	degree_centrality	pocket	druggability	num_drug_pockets	struct_score	logFC	regulation	citation_score
IL4I1	Q96RQ9	10	0	1	0.511	1.000	1	86.82116	7.731687	up_reg	124
MAPK15	Q8TD08	20	0	1	0.055	1.000	1	69.39014	4.731041	up_reg	63
CACNA1F	O60840	2	1139	3	0.170	0.999	5	67.32468	3.652392	up_reg	184
AQP9	O43315	2	0	1	0.470	0.998	1	91.06600	3.553111	up_reg	637
SULT1C2	O00338	53	0	1	0.298	0.998	1	95.75467	4.617490	up_reg	56
CENPE	Q02224	2	1501	4	0.135	0.997	5	72.55249	2.847355	up_reg	436
RYR1	P21817	2	1899	4	0.226	0.997	3	75.55434	3.086482	up_reg	7993
BNIPL	Q7Z465	2	0	1	0.190	0.996	1	68.65183	3.984513	up_reg	17
SULT2B1	O00204	53	0	1	0.599	0.996	1	87.72190	4.651085	up_reg	124
FAAH2	Q6GMR7	23	0	1	0.082	0.995	1	94.18245	3.735525	up_reg	24
CD9	P21926	2	1521	3	0.063	0.994	1	88.11915	3.619361	up_reg	2704
CENPU	Q71F23	2	0	3	0.002	0.994	1	65.51860	3.558826	up_reg	59
KCNK12	Q9HB15	36	0	1	0.139	0.994	1	73.78490	2.598125	up_reg	25
MELK	Q14680	2	0	1	0.159	0.993	1	70.64372	5.528457	up_reg	659
NOX4	Q9NPH5	2	322	2	0.046	0.993	3	86.75705	2.565399	up_reg	3755
PLPP4	Q5VZY2	45	0	1	0.383	0.993	2	92.00338	5.658002	up_reg	11
XDH	P47989	46	0	1	0.138	0.993	3	96.09594	7.452060	up_reg	800
IDO1	P14902	34	0	1	0.277	0.991	1	93.39839	5.743478	up_reg	2039
KIF11	P52732	2	1046	9	0.141	0.991	1	74.76864	4.407716	up_reg	820
KLC3	Q6P597	11	3	3	0.212	0.991	1	76.01520	4.822387	up_reg	19
RYR1	P21817	2	1899	4	0.145	0.989	2	76.51895	3.086482	up_reg	7993
CYP2J2	P51589	22	0	1	0.080	0.987	1	93.78906	4.606358	up_reg	707
NINJ2	Q9NZG7	2	0	1	0.185	0.987	3	67.54372	3.668185	up_reg	59
TEAD4	Q15561	2	1521	3	0.243	0.986	2	76.58312	2.660133	up_reg	381
UNC93B1	Q9H1C4	54	0	1	0.082	0.986	1	80.17879	3.392612	up_reg	175
LY86	O95711	15	0	1	0.075	0.983	1	87.70983	3.088945	up_reg	119
TNFAIP8L2	Q6P589	2	761	2	0.017	0.981	1	90.74994	2.015314	up_reg	130
SYK	P43405	2	13379	10	0.203	0.979	2	84.33036	4.407191	up_reg	5393
FBN2	P35556	12	7	3	0.107	0.975	1	75.78393	2.521524	up_reg	313
CACNA1B	Q00975	2	6	2	0.130	0.971	2	60.38413	4.783153	up_reg	334
HAS2	Q92819	2	0	1	0.103	0.970	1	90.70737	2.317929	up_reg	1108
SLC35F2	Q8IXU6	2	0	1	-0.002	0.970	2	82.73241	2.149731	up_reg	26
LGR6	Q9HBX8	37	0	2	0.408	0.967	2	78.17419	3.761788	up_reg	191
LPAR5	Q9H1C0	2	0	1	0.250	0.967	1	83.69589	3.173233	up_reg	108
ALDH3A1	P30838	5	0	2	0.345	0.966	1	97.89977	3.119278	up_reg	316
SGPP2	Q8IWX5	45	0	1	0.102	0.966	1	84.21180	5.853240	up_reg	40
VDR	P11473	2	0	1	0.284	0.966	1	84.69541	3.683154	up_reg	8882
H2BC4	P62807	2	38282	12	0.291	0.965	1	87.82973	2.638893	up_reg	0
LAPTM5	Q13571	38	0	1	0.239	0.964	2	69.27503	2.290592	up_reg	113
NQO1	P15559	2	761	2	0.254	0.963	1	98.32853	2.893693	up_reg	5539
SLC16A3	O15427	2	1520	2	0.025	0.963	1	83.58743	2.015156	up_reg	195
NAXE	Q8NCW5	2	1521	3	0.423	0.962	1	86.87614	2.208627	up_reg	51
CYP4F3	Q08477	22	0	1	0.156	0.961	2	91.82752	4.018495	up_reg	84
TGFA	P01135	2	3905	5	0.202	0.961	1	66.88685	4.466767	up_reg	481
ADGRG1	Q9Y653	2	0	1	0.294	0.960	2	78.01376	4.084734	up_reg	168
CENPE	Q02224	2	1501	4	0.126	0.960	2	70.76444	2.847355	up_reg	436
DNAH3	Q8TD57	24	0	1	0.164	0.960	4	85.66639	3.642484	up_reg	16
STC2	O76061	2	0	2	0.270	0.960	2	73.29585	3.187642	up_reg	353
FBN3	Q75N90	12	0	1	0.195	0.958	2	75.30388	5.054065	up_reg	53
CYBA	P13498	2	0	2	0.480	0.957	1	77.02989	3.871486	up_reg	1043
TTK	P33981	2	3035	3	0.087	0.956	1	63.95435	5.915254	up_reg	2047
PLK1	P53350	2	53880	14	0.175	0.953	2	85.16989	3.894749	up_reg	2971
CYBB	P04839	2	1700	2	0.295	0.952	3	90.39584	2.576950	up_reg	2670
ERBB4	Q15303	2	3810	3	0.069	0.951	1	73.09162	5.365254	up_reg	2501
TSPAN33	Q86UF1	2	0	1	0.034	0.951	2	89.66649	2.598895	up_reg	32
DSP	P15924	2	2832	2	0.154	0.950	1	78.56539	4.716943	up_reg	5445
IL32	P24001	2	0	1	0.099	0.950	2	71.19002	3.002851	up_reg	626
ASPM	Q8IZT6	2	8922	4	0.434	0.949	4	62.64048	4.312243	up_reg	510
CENPE	Q02224	2	1501	4	0.416	0.949	1	70.84160	2.847355	up_reg	436
NDUFB9	Q9Y6M9	2	4536	2	-0.051	0.948	1	96.13232	2.289772	up_reg	33
AIFM1	O95831	2	39	2	0.136	0.947	1	85.79458	2.212459	up_reg	647
TDO2	P48775	34	0	1	0.175	0.947	1	90.52437	5.860687	up_reg	223
LAMA5	O15230	2	3467	4	0.086	0.946	2	79.24314	2.244719	up_reg	154
GPR37	O15354	2	0	1	0.097	0.945	5	61.81102	4.508915	up_reg	144
RTN2	O75298	49	0	1	0.162	0.944	2	51.12613	2.365362	up_reg	37
GJB2	P29033	2	1520	2	0.236	0.943	2	86.38640	5.456850	up_reg	2564
PTGS1	P23219	2	0	2	0.142	0.943	1	94.11557	5.423793	up_reg	3039
IFI27	P40305	2	0	1	0.066	0.942	1	52.14211	4.811702	up_reg	273
MYO3B	Q8WXR4	2	0	2	0.144	0.942	1	75.66990	6.420588	up_reg	22
TNFRSF12A	Q9NP84	2	1609	4	0.111	0.942	1	73.27291	3.640033	up_reg	446
DNAH3	Q8TD57	24	0	1	0.099	0.941	1	85.25115	3.642484	up_reg	16
TRPV6	Q9H1D0	2	0	1	0.341	0.941	3	80.74593	3.389083	up_reg	747
H2BC9	Q93079	2	24695	11	0.364	0.940	2	88.14311	4.450921	up_reg	3
RORC	P51449	2	0	1	0.252	0.940	1	75.84376	4.448796	up_reg	1288
TNFSF10	P50591	2	761	2	0.184	0.940	1	82.39667	2.187216	up_reg	3737
P2RY2	P41231	43	0	1	0.120	0.939	1	79.19662	4.039141	up_reg	470
RAC2	P15153	2	1171	7	0.227	0.939	1	93.54571	2.156389	up_reg	917
RIMKLA	Q8IXN7	2	0	1	0.297	0.938	1	81.13650	3.884952	up_reg	4
H2BC12	O60814	2	24896	11	0.241	0.937	1	88.05779	3.203629	up_reg	2
MPZL2	O60487	40	0	1	0.433	0.937	2	89.47771	3.309876	up_reg	35
RAC3	P60763	2	18877	11	0.341	0.937	1	93.83371	2.514936	up_reg	299
DNAH5	Q8TE73	24	0	1	0.234	0.936	1	81.69210	3.828651	up_reg	183
IL2RA	P01589	2	0	1	0.000	0.936	1	72.50829	2.966958	up_reg	1993
RSAD2	Q8WXG1	2	380	2	0.193	0.935	1	87.95684	2.536852	up_reg	393
PPP4C	P60510	2	1521	3	0.387	0.933	1	94.87746	2.136177	up_reg	32
DNAH5	Q8TE73	24	0	1	0.124	0.932	3	85.07114	3.828651	up_reg	183
IFIT1	P09914	2	0	1	0.057	0.930	1	94.17439	2.860614	up_reg	577
MUC5B	Q9HC84	2	1020	3	0.112	0.930	1	82.35068	5.737039	up_reg	1207
APOA1	P02647	2	9356	8	0.278	0.929	3	73.61168	3.065972	up_reg	3491
ASPM	Q8IZT6	2	8922	4	0.335	0.927	1	64.38947	4.312243	up_reg	510
CDC45	O75419	2	884	2	0.323	0.926	1	92.88743	4.831525	up_reg	594
FBN2	P35556	12	7	3	0.286	0.926	1	75.56676	2.521524	up_reg	313
CDC6	Q99741	2	761	3	0.244	0.922	2	69.83948	3.142206	up_reg	1059
CHST6	Q9GZX3	18	0	1	0.409	0.920	1	90.80083	5.468416	up_reg	84
LAMA5	O15230	2	3467	4	0.241	0.919	3	79.99285	2.244719	up_reg	154
LAMA5	O15230	2	3467	4	0.244	0.918	2	82.41367	2.244719	up_reg	154
NR2F6	P10588	2	0	1	0.399	0.917	1	79.75002	3.297460	up_reg	89
SDC4	P31431	2	4689	3	0.270	0.917	2	63.14462	2.128542	up_reg	556
DNAH5	Q8TE73	24	0	1	2.178	0.916	3	87.27259	3.828651	up_reg	183
LGALS9	O00182	2	0	1	0.247	0.914	3	85.12848	2.655331	up_reg	533
FBN3	Q75N90	12	0	1	0.138	0.909	1	70.40952	5.054065	up_reg	53
EPPK1	P58107	2	0	1	0.247	0.908	1	77.46931	6.941326	up_reg	38
CENPF	P49454	2	10672	3	0.122	0.906	1	71.41875	4.302935	up_reg	385
ATP10B	O94823	9	0	1	0.117	0.904	2	71.43291	5.180540	up_reg	18
HCST	Q9UBK5	2	1076	3	0.330	0.904	2	67.31898	2.736939	up_reg	246
ASS1	P00966	2	0	1	0.103	0.902	1	95.63537	3.299729	up_reg	402
AGR2	O95994	2	5272	5	0.263	0.901	1	87.41946	5.133482	up_reg	449
CDCP1	Q9H5V8	2	0	1	0.276	0.901	1	78.35387	5.466835	up_reg	234
PBK	Q96KB5	2	0	2	0.152	0.901	1	84.90700	5.819542	up_reg	782
MGST1	P10620	39	0	1	0.541	0.900	1	79.02661	3.365294	up_reg	238
RYR1	P21817	2	1899	4	0.185	0.900	2	84.43495	3.086482	up_reg	7993
ATP5MC1	P05496	2	3791	3	0.401	0.898	1	72.69576	2.063501	up_reg	4
TOP2A	P11388	2	22036	7	0.045	0.897	1	76.40832	5.212828	up_reg	1327
ITGB8	P26012	2	0	1	0.085	0.896	1	76.46707	2.820420	up_reg	131
ATP5MF	P56134	2	0	1	0.423	0.892	3	74.16835	2.318005	up_reg	2
CTSC	P53634	2	0	3	0.338	0.892	2	90.37857	2.162863	up_reg	316
PTX3	P26022	2	135	2	0.266	0.891	2	79.75132	2.728436	up_reg	2010
DSP	P15924	2	2832	2	0.293	0.890	1	79.72187	4.716943	up_reg	5445
GJB1	P08034	2	0	1	0.333	0.890	1	80.05050	7.474133	up_reg	358
DNAH5	Q8TE73	24	0	1	0.237	0.889	1	80.09468	3.828651	up_reg	183
ZNF492	Q9P255	56	0	1	0.218	0.888	1	73.55861	2.697025	up_reg	6
KLHL14	Q9P2G3	6	0	1	0.483	0.887	1	88.14009	5.754363	up_reg	22
LRP2	P98164	2	761	2	0.255	0.887	1	81.80994	4.927297	up_reg	452
ANPEP	P15144	2	761	2	0.232	0.886	1	93.75126	3.535249	up_reg	188
HMMR	O75330	2	0	1	0.192	0.886	2	76.10490	5.098101	up_reg	249
DNAH3	Q8TD57	24	0	1	0.172	0.885	2	86.96104	3.642484	up_reg	16
ESPL1	Q14674	2	0	1	0.619	0.885	1	75.77835	4.967101	up_reg	146
KIF9	Q9HAQ2	2	7104	13	0.202	0.885	1	75.21325	2.195679	up_reg	31
CD3E	P07766	2	14667	11	0.191	0.884	1	73.51280	2.881956	up_reg	540
BIK	Q13323	2	761	2	0.409	0.883	2	62.54290	6.029953	up_reg	1275
TUBA1C	Q9BQE3	2	861	2	0.219	0.883	1	91.65244	3.360826	up_reg	52
CIT	O14578	2	4278	2	0.129	0.882	1	70.15278	3.109393	up_reg	8634
PKP3	Q9Y446	2	31976	3	0.070	0.881	1	69.28451	7.141531	up_reg	91
CENPE	Q02224	2	1501	4	0.191	0.880	2	74.15316	2.847355	up_reg	436
DNAH5	Q8TE73	24	0	1	0.179	0.880	2	80.01153	3.828651	up_reg	183
FBN2	P35556	12	7	3	0.139	0.880	1	75.06254	2.521524	up_reg	313
TJP3	O95049	2	0	4	0.067	0.880	2	66.58409	6.724088	up_reg	60
LRRC43	Q8N309	2	0	1	0.240	0.879	1	74.70035	2.069984	up_reg	0
DNAH3	Q8TD57	24	0	1	0.312	0.878	4	88.06644	3.642484	up_reg	16
GRIK3	Q13003	2	17866	8	0.152	0.878	1	82.38048	3.473939	up_reg	66
BAIAP2L1	Q9UHR4	2	3579	4	0.324	0.876	2	74.93578	4.062937	up_reg	46
TSPAN15	O95858	2	2277	2	0.296	0.875	2	87.94298	3.591096	up_reg	34
HLA-DOA	P06340	2	7	4	0.429	0.874	1	90.25303	3.324934	up_reg	61
FUT2	Q10981	32	0	1	0.311	0.872	2	90.42101	2.453333	up_reg	560
LRP2	P98164	2	761	2	0.153	0.871	1	76.00288	4.927297	up_reg	452
H2BC11	P06899	2	72	9	0.250	0.870	2	85.69804	3.968938	up_reg	1
KREMEN2	Q8NCW0	37	0	1	0.459	0.870	1	76.82793	7.640887	up_reg	36
KIF15	Q9NS87	2	2175	7	0.241	0.869	1	72.02130	3.950703	up_reg	155
PYCR1	P32322	47	0	1	0.336	0.869	2	90.06781	2.897004	up_reg	158
IL23A	Q9NPF7	2	0	1	0.205	0.868	2	80.95746	2.267386	up_reg	706
DIAPH3	Q9NSV4	2	322	2	0.164	0.866	2	71.81813	4.609425	up_reg	86
LAPTM4B	Q86VI4	38	0	1	0.211	0.865	1	61.67725	3.214999	up_reg	179
SLC5A1	P13866	2	0	1	0.444	0.865	1	84.10975	6.574268	up_reg	812
DNAH3	Q8TD57	24	0	1	0.156	0.864	1	85.29108	3.642484	up_reg	16
SVOPL	Q8N434	49	0	1	0.061	0.862	1	84.05384	3.101728	up_reg	14
RYR1	P21817	2	1899	4	0.108	0.861	2	81.22953	3.086482	up_reg	7993
CXADR	P78310	2	0	1	0.405	0.860	1	79.48562	5.200874	up_reg	83
MARVELD3	Q96A59	2	0	3	0.108	0.860	1	65.32157	3.677035	up_reg	36
NRCAM	Q92823	2	1726	4	0.090	0.859	2	78.95628	2.470745	up_reg	323
HTR3A	P46098	2	0	1	0.422	0.858	2	83.46451	10.598163	up_reg	265
PROM1	O43490	2	335	2	0.171	0.857	2	85.89768	5.868539	up_reg	2840
SLC7A7	Q9UM01	2	0	1	0.011	0.853	1	83.51919	2.184124	up_reg	198
ARFGEF3	Q5TH69	2	0	1	0.051	0.852	3	65.48151	3.121775	up_reg	16
CACNA1A	O00555	2	4536	3	0.201	0.851	2	57.97536	2.232175	up_reg	1045
CXXC5	Q7LFL8	2	0	1	0.110	0.849	1	60.75966	4.423334	up_reg	99
BUB1B	O60566	2	3360	6	0.211	0.846	2	64.72058	4.320179	up_reg	471
GRIN2D	O15399	2	0	2	0.143	0.846	3	64.00209	3.116091	up_reg	93
USP43	Q70EL4	2	470	2	0.025	0.846	2	61.36801	3.739775	up_reg	14
LAMB3	Q13751	2	0	1	0.212	0.844	2	78.10768	4.685454	up_reg	288
POSTN	Q15063	2	0	1	0.152	0.839	2	80.24478	2.937741	up_reg	1643
SLC2A1	P11166	2	2279	3	0.190	0.839	1	89.61531	3.442262	up_reg	3562
CCNO	P22674	2	761	3	0.405	0.838	2	79.73102	2.663074	up_reg	142
ASPM	Q8IZT6	2	8922	4	0.121	0.835	1	67.46659	4.312243	up_reg	510
DNAH5	Q8TE73	24	0	1	0.335	0.834	3	83.36204	3.828651	up_reg	183
LRP2	P98164	2	761	2	0.105	0.834	5	80.79603	4.927297	up_reg	452
IL27RA	Q6UWB1	2	761	2	0.336	0.833	1	79.02110	2.953478	up_reg	214
LAMA5	O15230	2	3467	4	0.204	0.833	5	78.94328	2.244719	up_reg	154
TYMP	P19971	46	0	1	0.402	0.833	2	93.01893	2.648306	up_reg	270
CX3CR1	P49238	2	1960	6	0.114	0.832	2	80.21817	4.725471	up_reg	3143
WNT7B	P56706	2	0	1	0.461	0.832	2	89.56172	7.353727	up_reg	427
MRPL47	Q9HD33	2	1164	3	0.233	0.830	1	84.37084	2.125313	up_reg	12
TMC6	Q7Z403	2	761	2	0.125	0.830	6	72.55287	2.977559	up_reg	76
IRF6	O14896	2	90	2	0.289	0.829	1	74.17857	3.540215	up_reg	507
FSBP	O95073	2	0	1	0.297	0.828	1	70.03120	2.914093	up_reg	58
RET	P07949	2	3789	4	0.127	0.827	1	79.44206	2.801801	up_reg	11194
CENPF	P49454	2	10672	3	0.372	0.826	1	72.00170	4.302935	up_reg	385
GJB3	O75712	2	761	2	0.462	0.826	4	79.18052	6.360123	up_reg	328
KCNJ12	Q14500	2	0	1	0.160	0.823	2	81.21053	2.050148	up_reg	50
LAMC2	Q13753	2	0	1	0.153	0.822	1	74.86195	4.997825	up_reg	472
LRP2	P98164	2	761	2	0.226	0.822	1	82.61401	4.927297	up_reg	452
FAM3B	P58499	30	0	1	0.319	0.821	2	93.09627	6.055449	up_reg	64
UPK3B	Q9BT76	2	0	1	0.394	0.821	1	52.89733	4.391774	up_reg	21
ASPM	Q8IZT6	2	8922	4	0.163	0.820	2	68.83865	4.312243	up_reg	510
BCL2L1	Q07817	2	2177	5	0.269	0.820	1	73.63605	2.256294	up_reg	8522
ADGRE2	Q9UHX3	2	0	1	0.306	0.819	2	79.23141	2.147655	up_reg	49
NDUFB11	Q9NX14	2	0	1	0.410	0.818	1	78.63169	2.037892	up_reg	35
RASAL1	O95294	2	0	1	0.120	0.818	3	88.58747	6.257054	up_reg	78
CYC1	P08574	2	0	1	0.109	0.817	1	86.38440	2.331383	up_reg	883
CENPA	P49450	2	17610	6	0.140	0.815	2	82.07836	6.059723	up_reg	1089
BMP7	P18075	12	7	3	0.232	0.814	2	76.70694	7.157820	up_reg	3269
KIF20A	O95235	2	24557	13	0.333	0.814	3	67.30456	5.657319	up_reg	301
DSP	P15924	2	2832	2	0.471	0.813	1	76.57581	4.716943	up_reg	5445
CXCL16	Q9H2A7	2	40	2	0.204	0.808	2	65.97562	3.366446	up_reg	927
FBN3	Q75N90	12	0	1	0.154	0.808	1	75.06968	5.054065	up_reg	53
RYR1	P21817	2	1899	4	0.422	0.808	6	80.58427	3.086482	up_reg	7993
DNAH3	Q8TD57	24	0	1	0.199	0.807	4	87.74512	3.642484	up_reg	16
LAMA5	O15230	2	3467	4	0.150	0.804	1	81.67851	2.244719	up_reg	154
ASPM	Q8IZT6	2	8922	4	0.163	0.803	2	63.49329	4.312243	up_reg	510
TRPV4	Q9HBA0	2	761	2	0.132	0.803	5	72.00033	3.177434	up_reg	2211
DNAH5	Q8TE73	24	0	1	0.137	0.802	1	88.53234	3.828651	up_reg	183
SMAD1	Q15797	2	0	1	0.240	0.801	1	81.78024	2.105853	up_reg	3204
ALG3	Q92685	6	0	1	0.084	0.800	1	89.19005	2.839320	up_reg	131
LRRC46	Q96FV0	2	0	1	0.095	0.800	1	64.78600	2.513569	up_reg	7
NOTUM	Q6P988	2	0	1	0.466	0.800	1	84.58992	7.917860	up_reg	341
TPM3	P06753	2	8572	8	0.348	0.799	1	91.78888	2.201758	up_reg	485
TREM2	Q9NZC2	2	0	2	0.411	0.799	1	77.04992	3.818614	up_reg	1706
MUC16	Q8WXI7	2	1521	3	0.180	0.798	1	55.96839	8.476038	up_reg	1352
NRAS	P01111	2	8745	6	0.256	0.798	1	92.29668	2.115169	up_reg	7121
NKG7	Q16617	2	0	1	0.270	0.797	1	86.50265	3.348089	up_reg	82
SLC12A5	Q9H2X9	42	0	1	0.167	0.797	3	78.73929	2.764017	up_reg	143
BRCA2	P51587	2	32217	9	0.083	0.796	1	65.83808	2.245119	up_reg	14293
VANGL1	Q8TAA9	2	4805	6	0.038	0.796	2	75.85692	2.706602	up_reg	163
DAPP1	Q9UN19	2	0	1	0.046	0.794	1	79.27173	3.771736	up_reg	58
B3GNT3	Q9Y2A9	2	3789	3	0.149	0.793	1	88.42372	7.460360	up_reg	42
DSC3	Q14574	2	0	1	0.135	0.793	1	74.81262	2.160385	up_reg	181
RTKN	Q9BST9	2	0	1	0.115	0.793	1	72.73822	2.656687	up_reg	69
CENPF	P49454	2	10672	3	0.307	0.792	6	71.55613	4.302935	up_reg	385
SECTM1	Q8WVN6	2	0	1	0.407	0.792	1	75.41749	2.268843	up_reg	26
SCARA3	Q6AZY7	50	0	1	0.222	0.790	4	71.06544	2.625480	up_reg	53
AURKB	Q96GD4	2	7020	6	0.060	0.789	2	79.85404	5.582702	up_reg	1367
PIPOX	Q9P0Z9	2	453	2	0.845	0.789	3	94.41585	3.104421	up_reg	59
FUT1	P19526	32	0	1	0.333	0.788	1	88.46001	2.677239	up_reg	317
KRT86	O43790	2	13	5	0.408	0.788	4	75.55742	5.650357	up_reg	27
ACTR3C	Q9C0K3	2	0	1	0.040	0.786	1	88.11260	2.000050	up_reg	2
MX2	P20592	2	0	1	0.177	0.784	1	78.01712	2.755543	up_reg	1098
RYR1	P21817	2	1899	4	0.176	0.784	3	82.30215	3.086482	up_reg	7993
TIMELESS	Q9UNS1	2	2280	6	0.482	0.784	2	75.06448	2.414253	up_reg	1146
BRCA2	P51587	2	32217	9	0.066	0.783	2	62.08251	2.245119	up_reg	14293
FCER1G	P30273	2	1521	4	0.480	0.783	1	72.33766	3.253477	up_reg	173
LAMA5	O15230	2	3467	4	0.102	0.782	2	78.13025	2.244719	up_reg	154
CDC25C	P30307	2	0	1	0.362	0.777	1	64.18249	6.227772	up_reg	1461
RAB27B	O00194	2	0	1	0.070	0.777	1	86.79901	2.886397	up_reg	230
DNAH5	Q8TE73	24	0	1	0.230	0.776	2	85.04038	3.828651	up_reg	183
HLA-DPA1	P20036	2	40869	5	0.282	0.776	1	90.64308	3.525234	up_reg	363
PIGR	P01833	35	0	1	0.017	0.776	1	77.21791	3.975115	up_reg	702
CHAC1	Q9BUX1	17	0	1	0.391	0.775	1	86.16639	2.901424	up_reg	155
TNFSF15	O95150	2	0	1	0.272	0.775	2	82.11392	4.283946	up_reg	467
CCR5	P51681	2	119	2	0.253	0.774	1	85.29439	2.420445	up_reg	10827
GZMB	P10144	2	2279	3	0.347	0.774	1	92.52045	4.083414	up_reg	2459
FGF18	O76093	2	620	2	0.380	0.771	2	87.67060	5.957364	up_reg	396
ST14	Q9Y5Y6	51	0	1	0.160	0.771	2	81.25730	7.158208	up_reg	577
WDR62	O43379	2	0	1	0.088	0.770	2	61.36502	3.041289	up_reg	124
ASPM	Q8IZT6	2	8922	4	0.107	0.769	2	62.01828	4.312243	up_reg	510
CENPF	P49454	2	10672	3	0.416	0.769	3	73.15360	4.302935	up_reg	385
PLEKHH1	Q9ULM0	2	0	1	0.175	0.767	2	70.18185	2.350357	up_reg	4
FZD2	Q14332	2	1521	3	0.544	0.766	4	84.43777	2.649653	up_reg	254
LGR5	O75473	37	3	2	0.267	0.766	4	80.74472	3.946516	up_reg	2020
ORC1	Q13415	2	2071	4	0.154	0.765	1	67.97461	2.787799	up_reg	375
ALPL	P05186	2	0	1	0.370	0.761	2	93.75407	4.455983	up_reg	1060
ANLN	Q9NQW6	2	10469	5	0.121	0.760	1	59.87419	3.455958	up_reg	227
PAK6	Q9NQU5	2	0	1	0.452	0.760	4	67.07498	3.389624	up_reg	123
TUBA1B	P68363	2	117	2	0.192	0.760	2	92.25708	2.287882	up_reg	57
LYN	P07948	2	49848	19	0.072	0.759	1	83.72670	2.498330	up_reg	3594
SLC7A11	Q9UPY5	2	761	2	0.376	0.758	3	86.60983	2.106353	up_reg	1518
ASPM	Q8IZT6	2	8922	4	0.305	0.756	1	71.82009	4.312243	up_reg	510
THY1	P04216	2	761	2	0.334	0.756	1	83.05667	3.086846	up_reg	6210
LMNB1	P20700	2	325	2	0.275	0.754	2	82.63466	3.288592	up_reg	199
NDUFB7	P17568	2	0	1	0.266	0.753	1	88.93270	2.055041	up_reg	31
CCR1	P32246	2	719	3	0.143	0.752	1	83.11436	2.538960	up_reg	1807
LRP2	P98164	2	761	2	0.224	0.752	1	87.38054	4.927297	up_reg	452
MSR1	P21757	2	2506	6	0.363	0.749	1	71.98684	2.514585	up_reg	611
EYA2	O00167	28	2	2	0.223	0.748	1	69.03617	6.536633	up_reg	130
RYR1	P21817	2	1899	4	0.194	0.748	1	75.79852	3.086482	up_reg	7993
CD180	Q99467	15	0	1	0.355	0.747	1	93.23928	3.301753	up_reg	151
CENPL	Q8N0S6	2	4202	4	0.229	0.746	2	83.65047	2.321809	up_reg	22
AMN	Q9BXJ7	2	0	1	0.320	0.745	1	80.93990	5.031542	up_reg	1960
CBLC	Q9ULV8	2	102	2	0.215	0.744	1	81.16177	8.008650	up_reg	381
TXK	P42681	2	1520	2	0.210	0.743	1	80.40473	2.723460	up_reg	90
LRP2	P98164	2	761	2	0.346	0.742	1	82.33059	4.927297	up_reg	452
CENPE	Q02224	2	1501	4	0.304	0.741	2	72.44087	2.847355	up_reg	436
ACOT4	Q8N9L9	3	0	1	0.140	0.740	1	96.46060	2.828725	up_reg	23
RGS19	P49795	2	0	1	0.119	0.740	2	79.47628	3.524701	up_reg	63
ASB9	Q96DX5	8	1	2	0.225	0.738	1	92.22385	2.355072	up_reg	31
UNC5A	Q6ZN44	2	0	1	0.108	0.737	1	78.25560	5.877999	up_reg	71
SPTBN2	O15020	2	4273	4	0.242	0.736	3	76.77521	4.481006	up_reg	98
CD109	Q6YHK3	2	761	2	0.287	0.734	2	81.37547	2.781852	up_reg	265
FUT3	P21217	30	0	1	0.263	0.734	2	90.59422	4.921716	up_reg	215
DNAH3	Q8TD57	24	0	1	0.165	0.733	3	84.86977	3.642484	up_reg	16
DSP	P15924	2	2832	2	0.212	0.733	3	80.80300	4.716943	up_reg	5445
ALDH3B2	P48448	5	0	2	0.218	0.732	2	94.98486	8.969782	up_reg	26
BTC	P35070	2	2783	3	0.290	0.731	1	72.38943	2.703718	up_reg	3190
NDUFA3	O95167	2	0	1	0.274	0.730	1	96.84498	2.073884	up_reg	15
CFAP45	Q9UL16	2	1552	5	0.131	0.728	3	74.80989	2.226990	up_reg	15
RYR1	P21817	2	1899	4	0.067	0.728	2	74.31304	3.086482	up_reg	7993
BCAM	P50895	2	0	1	0.182	0.725	3	84.58449	4.415965	up_reg	425
CNIH2	Q6PI25	2	19080	5	0.314	0.723	2	87.25387	2.690596	up_reg	37
KRT8	P05787	2	4632	6	0.432	0.721	1	76.32674	6.489903	up_reg	425
OSM	P13725	2	1111	2	0.107	0.721	1	79.62908	2.173526	up_reg	3150
MUC16	Q8WXI7	2	1521	3	0.177	0.720	2	77.36666	8.476038	up_reg	1352
MMP9	P14780	2	4920	4	0.191	0.717	2	82.25628	5.237949	up_reg	34223
POLQ	O75417	2	0	2	0.104	0.717	1	59.48627	3.988411	up_reg	184
MGST2	Q99735	39	0	1	0.330	0.715	1	93.94066	2.026180	up_reg	69
ATP6V0E2	Q8NHE4	2	1521	3	0.416	0.712	1	94.37485	2.427263	up_reg	8
CACNG4	Q9UBN1	2	5285	2	0.125	0.712	1	65.72441	6.967106	up_reg	36
KPNA2	P52292	2	2308	5	0.024	0.711	1	86.10732	3.953899	up_reg	312
SHCBP1	Q8NEM2	2	0	1	0.180	0.711	1	73.69646	2.980451	up_reg	65
GPR19	Q15760	27	0	1	0.271	0.708	2	74.77012	5.197318	up_reg	30
SPC25	Q9HBM1	2	0	1	0.390	0.708	1	90.25548	4.349788	up_reg	106
FAM166B	A8MTA8	2	0	6	0.110	0.707	1	69.27333	3.014622	up_reg	4
FANCA	O15360	2	2277	2	0.135	0.707	1	74.56587	2.596562	up_reg	687
CMPK2	Q5EBM0	21	0	1	0.064	0.706	2	87.31019	3.113808	up_reg	67
PERP	Q96FX8	2	31898	6	0.129	0.705	1	82.35155	3.211249	up_reg	673
FOXM1	Q08050	2	1527	4	0.173	0.701	1	51.07629	5.310591	up_reg	2251
CRB3	Q9BUF7	2	0	1	0.297	0.700	1	70.34841	6.178867	up_reg	484
DNAH3	Q8TD57	24	0	1	0.127	0.700	3	86.03215	3.642484	up_reg	16
FBN2	P35556	12	7	3	0.177	0.700	2	74.88673	2.521524	up_reg	313
CCNB1	P14635	2	76783	14	0.078	0.699	1	77.77241	3.784353	up_reg	2285
CD6	P30203	2	0	1	0.079	0.699	1	66.69789	2.141497	up_reg	697
CD7	P09564	2	1521	3	0.383	0.699	2	77.62312	2.751900	up_reg	2691
FYB1	O15117	2	0	1	0.418	0.698	1	58.39229	2.503950	up_reg	86
EGLN3	Q9H6Z9	2	0	1	0.068	0.697	3	91.56092	3.193540	up_reg	295
NCAPD2	Q15021	2	0	3	0.115	0.697	1	79.98735	2.560562	up_reg	36
PLPP2	O43688	45	1	2	0.205	0.694	1	85.85271	3.843634	up_reg	14
STIL	Q15468	2	0	1	0.163	0.693	1	53.64950	3.519855	up_reg	469
CD8A	P01732	2	558	3	0.263	0.692	1	79.23665	2.123590	up_reg	573
IL1RAP	Q9NPH3	2	0	1	0.211	0.692	1	86.22484	3.030829	up_reg	257
DNAH5	Q8TE73	24	0	1	0.169	0.690	3	86.65257	3.828651	up_reg	183
LDHA	P00338	2	0	2	0.089	0.690	1	96.06050	2.195336	up_reg	2225
TNFRSF11B	O00300	2	0	1	0.349	0.688	1	87.00873	4.469606	up_reg	2628
CSPG5	O95196	2	0	1	0.081	0.686	1	52.88670	4.429149	up_reg	42
GRIN2A	Q12879	2	4542	3	0.064	0.686	1	60.41927	3.737127	up_reg	429
NCAPH	Q15003	2	0	3	0.198	0.683	1	60.71979	5.188544	up_reg	71
RAB6B	Q9NRW1	2	0	1	0.239	0.683	1	86.02474	2.332450	up_reg	35
SKA3	Q8IX90	2	4414	4	0.354	0.683	1	64.75869	5.662079	up_reg	97
LAMA5	O15230	2	3467	4	0.157	0.682	2	80.88889	2.244719	up_reg	154
ATP2B2	Q01814	2	0	1	0.151	0.681	2	73.94863	4.507063	up_reg	155
DNAH3	Q8TD57	24	0	1	0.134	0.681	1	85.22852	3.642484	up_reg	16
KCP	Q6ZWJ8	12	0	1	0.112	0.681	2	72.93541	4.945915	up_reg	315
LRP2	P98164	2	761	2	0.348	0.681	2	78.34824	4.927297	up_reg	452
PIK3CG	P48736	2	9360	4	0.145	0.681	2	88.42052	2.098934	up_reg	562
LAMA5	O15230	2	3467	4	0.061	0.679	2	75.26612	2.244719	up_reg	154
BRCA2	P51587	2	32217	9	0.092	0.678	3	62.85491	2.245119	up_reg	14293
CCDC6	Q16204	2	0	1	0.565	0.678	2	76.03680	2.126289	up_reg	199
USP18	Q9UMW8	2	0	1	0.065	0.678	1	84.05593	3.392279	up_reg	351
RYR1	P21817	2	1899	4	0.064	0.677	3	82.11736	3.086482	up_reg	7993
TRIP13	Q15645	2	1521	3	0.249	0.677	2	86.97940	3.848280	up_reg	197
HAVCR2	Q8TDQ0	2	1520	2	0.115	0.676	2	71.85756	2.594164	up_reg	1252
ASPM	Q8IZT6	2	8922	4	0.448	0.675	3	63.92800	4.312243	up_reg	510
BCAT1	P54687	10	0	1	0.358	0.674	1	95.00595	2.614531	up_reg	265
PKMYT1	Q99640	2	16270	3	0.142	0.674	1	75.59028	5.618007	up_reg	107
WNT10A	Q9GZT5	2	0	1	0.100	0.672	1	80.83386	7.182905	up_reg	400
ASPM	Q8IZT6	2	8922	4	0.197	0.670	3	66.25757	4.312243	up_reg	510
CENPE	Q02224	2	1501	4	0.308	0.670	2	71.07051	2.847355	up_reg	436
LAMA5	O15230	2	3467	4	0.172	0.670	2	84.35481	2.244719	up_reg	154
SELL	P14151	2	714	2	0.321	0.670	1	85.32516	2.655413	up_reg	6836
DLGAP5	Q15398	2	4794	4	0.128	0.669	1	56.37102	5.302585	up_reg	180
DNAH5	Q8TE73	24	0	1	0.383	0.669	1	84.26657	3.828651	up_reg	183
RAD54L	Q92698	2	0	1	0.171	0.669	1	80.51223	4.209123	up_reg	180
APBB1IP	Q7Z5R6	2	5286	3	0.280	0.668	1	73.44023	2.145425	up_reg	56
DNAH3	Q8TD57	24	0	1	0.115	0.668	1	84.68082	3.642484	up_reg	16
HDAC9	Q9UKV0	2	8	6	0.104	0.668	2	64.41926	2.313913	up_reg	455
KIF4A	O95239	2	1470	2	0.244	0.668	3	72.17122	5.153087	up_reg	226
MRPS12	O15235	2	1743	3	0.312	0.667	1	87.35241	2.446360	up_reg	14
TMEM102	Q8N9M5	48	0	1	0.236	0.666	1	74.64646	3.553872	up_reg	5
CAPG	P40121	2	0	1	0.313	0.665	1	86.70529	3.387519	up_reg	249
DNAH3	Q8TD57	24	0	1	0.199	0.662	1	78.29482	3.642484	up_reg	16
FBN2	P35556	12	7	3	0.076	0.662	1	73.45494	2.521524	up_reg	313
FOLR1	P15328	2	608	4	0.090	0.662	1	91.11366	9.610444	up_reg	357
RAB3D	O95716	48	0	1	0.185	0.662	2	85.15368	2.740453	up_reg	166
COX5A	P20674	2	14138	6	0.376	0.660	1	88.10962	2.578447	up_reg	134
TREM1	Q9NP99	2	0	1	0.034	0.660	1	71.42913	3.025812	up_reg	1118
RYR1	P21817	2	1899	4	0.105	0.659	3	81.12296	3.086482	up_reg	7993
TUBB4B	P68371	2	4864	8	0.258	0.659	2	92.02804	2.059976	up_reg	44
XRCC2	O43543	2	761	5	0.516	0.659	1	87.09828	3.236290	up_reg	430
MCM4	P33991	2	9512	9	0.217	0.658	3	73.74330	2.743419	up_reg	448
NEK2	P51955	2	7688	2	0.136	0.658	2	78.74819	6.921414	up_reg	489
TLR7	Q9NYK1	54	0	1	0.198	0.657	4	87.54334	3.806294	up_reg	4757
LAMA5	O15230	2	3467	4	0.026	0.656	1	82.86351	2.244719	up_reg	154
TPX2	Q9ULW0	2	761	2	0.402	0.656	1	64.23851	6.263362	up_reg	684
CHST4	Q8NCG5	18	0	1	0.363	0.655	2	90.77228	5.171505	up_reg	34
NCAPG	Q9BPX3	2	0	3	0.163	0.655	1	82.50230	4.802859	up_reg	252
BAK1	Q16611	2	2279	3	0.535	0.654	2	81.54397	2.273926	up_reg	1896
SHISA9	B4DS77	2	0	1	0.277	0.654	1	56.95488	5.720736	up_reg	18
HLA-DRA	P01903	2	0	4	0.277	0.653	1	89.58587	3.994244	up_reg	1221
MYB	P10242	2	0	1	0.162	0.652	1	59.19859	5.712612	up_reg	9106
RNF43	Q68DV7	37	0	3	0.124	0.651	1	54.60221	2.425714	up_reg	369
ROMO1	P60602	2	636	2	0.413	0.649	3	78.13109	2.159277	up_reg	115
TMEM63C	Q9P1W3	2	0	1	0.125	0.649	1	74.57350	3.490019	up_reg	12
DLGAP3	O95886	2	0	1	0.282	0.648	1	50.70109	3.775359	up_reg	25
PARD6B	Q9BYG5	2	3192	2	0.345	0.647	1	71.24402	3.304514	up_reg	40
COL13A1	Q5TAT6	1	0	2	0.197	0.646	1	57.97463	2.870544	up_reg	75
AQP5	P55064	2	761	2	0.392	0.643	1	93.50506	7.968789	up_reg	1158
FOLH1	Q04609	2	2288	4	0.322	0.643	1	94.01397	2.144560	up_reg	1490
PCNA	P12004	2	4677	7	0.569	0.642	1	94.33015	2.104983	up_reg	25415
CDR2L	Q86X02	2	0	1	0.434	0.641	2	74.20117	3.691110	up_reg	26
DMTN	Q08495	2	0	1	0.221	0.641	1	64.63463	3.098244	up_reg	60
IGF2BP2	Q9Y6M1	2	761	2	0.107	0.640	1	77.75247	2.401479	up_reg	650
RAD51	Q06609	2	4984	5	0.282	0.640	1	91.59067	3.625870	up_reg	5831
ADD2	P35612	2	761	2	0.203	0.639	4	66.27120	3.978666	up_reg	80
DSP	P15924	2	2832	2	0.400	0.639	1	76.99875	4.716943	up_reg	5445
CLDN10	P78369	2	8628	9	0.400	0.636	1	79.69633	6.283497	up_reg	99
GINS4	Q9BRT9	2	0	2	0.324	0.635	1	90.74832	2.575322	up_reg	36
EPPK1	P58107	2	0	1	0.182	0.634	2	80.54692	6.941326	up_reg	38
GPRIN2	O60269	2	0	1	0.172	0.634	1	50.28259	4.769083	up_reg	23
TEC	P42680	2	2277	4	0.096	0.634	1	85.88542	2.329341	up_reg	6593
CD2	P06729	2	97	4	0.375	0.633	2	78.29759	3.177594	up_reg	18110
MYBL2	P10244	2	0	1	0.066	0.633	1	58.45051	6.939571	up_reg	478
CD24	P25063	2	0	1	0.228	0.632	1	63.89011	8.713693	up_reg	4011
CDK2AP1	O14519	16	0	1	0.451	0.632	1	76.36776	3.230913	up_reg	92
KCNN4	O15554	2	761	2	0.429	0.632	1	84.85052	3.886967	up_reg	641
SLC44A4	Q53GD3	2	0	1	0.128	0.632	1	83.76549	4.642249	up_reg	56
CLDN3	O15551	2	669	5	0.271	0.631	1	81.42759	10.441852	up_reg	485
KRT6A	P02538	2	969	5	0.307	0.631	1	69.50787	3.041425	up_reg	196
L1CAM	P32004	2	5550	4	0.068	0.631	1	79.35279	3.823699	up_reg	2439
NETO2	Q8NC67	42	0	1	0.302	0.631	1	72.42280	2.079967	up_reg	77
SYNE4	Q8N205	11	0	1	0.168	0.628	1	57.78246	4.109102	up_reg	9
DNAH5	Q8TE73	24	0	1	0.404	0.627	2	87.62569	3.828651	up_reg	183
CCL4	P13236	2	2410	3	0.270	0.626	1	88.97642	3.213667	up_reg	14603
KRT17	Q04695	2	81	3	0.276	0.626	1	79.60908	6.228925	up_reg	271
PLAU	P00749	2	998	3	0.414	0.626	1	82.30347	3.727477	up_reg	569
RIBC2	Q9H4K1	2	2064	7	0.365	0.625	1	86.74874	3.939408	up_reg	11
RMI2	Q96E14	2	2582	7	0.286	0.624	1	89.81185	2.702399	up_reg	75
H3C10	P68431	2	0	3	0.351	0.623	1	87.28692	2.688200	up_reg	0
H3C8	P68431	2	11	3	0.351	0.623	1	87.28692	7.878421	up_reg	0
PCP4	P48539	44	0	1	0.348	0.623	1	77.79623	3.572944	up_reg	144
NUF2	Q9BZD4	2	0	1	0.317	0.622	2	89.42833	4.636580	up_reg	201
ACKR2	O00590	2	3092	3	0.220	0.621	2	80.01695	4.237197	up_reg	100
DNAH5	Q8TE73	24	0	1	0.238	0.621	1	83.61957	3.828651	up_reg	183
ALK	Q9UM73	2	761	2	0.087	0.620	3	67.27647	4.194048	up_reg	14702
CABP4	P57796	2	0	1	0.276	0.620	1	66.10069	2.568051	up_reg	49
C1QC	P02747	2	940	2	0.290	0.619	1	81.16742	2.927810	up_reg	159
MAL2	Q969L2	2	0	1	0.336	0.619	1	84.15024	8.534437	up_reg	176
BLM	P54132	2	1899	5	0.161	0.616	1	60.95775	3.668059	up_reg	5420
CCND1	P24385	2	30015	9	0.313	0.616	2	88.55158	3.545879	up_reg	6387
DCTPP1	Q9H773	21	0	1	0.339	0.616	1	85.40514	2.697626	up_reg	24
SLC34A2	O95436	2	0	1	0.040	0.616	3	72.96990	7.493592	up_reg	287
CKAP2	Q8WWK9	19	0	1	0.332	0.615	2	59.53707	2.952651	up_reg	74
CENPN	Q96H22	2	0	2	0.300	0.612	1	86.20997	2.369029	up_reg	68
DNAH3	Q8TD57	24	0	1	0.286	0.612	4	84.67000	3.642484	up_reg	16
SLPI	P03973	2	0	1	0.442	0.612	1	84.39588	7.842239	up_reg	928
IL2RG	P31785	2	2925	4	0.234	0.609	1	76.81580	2.149183	up_reg	1136
BRCA2	P51587	2	32217	9	0.270	0.607	2	50.76375	2.245119	up_reg	14293
MPP7	Q5T2T1	2	322	2	0.114	0.606	1	81.02127	2.488989	up_reg	39
RYR1	P21817	2	1899	4	0.271	0.606	1	82.39230	3.086482	up_reg	7993
CD74	P04233	2	3917	5	0.198	0.605	1	70.67138	3.873722	up_reg	1184
CD96	P40200	2	0	1	0.113	0.605	1	66.54424	2.031664	up_reg	234
ESRP1	Q6NXG1	2	0	1	0.187	0.604	1	78.06816	8.042375	up_reg	197
IQGAP3	Q86VI3	2	0	1	0.181	0.604	2	79.62675	5.163314	up_reg	85
CDK2AP2	O75956	16	0	1	0.476	0.603	1	75.74548	2.120070	up_reg	40
FBN3	Q75N90	12	0	1	0.161	0.603	1	71.82553	5.054065	up_reg	53
HOOK1	Q9UJC3	2	0	1	0.269	0.603	3	82.67534	3.529558	up_reg	73
VAV1	P15498	2	853	3	0.182	0.602	2	87.14542	2.680345	up_reg	1025
CCL4L2	Q8NHW4	2	0	1	0.140	0.601	1	90.27970	2.125786	up_reg	18
DSC2	Q02487	2	3552	2	0.275	0.600	1	76.56279	5.332860	up_reg	297
PYCR3	Q53H96	47	0	1	0.416	0.600	1	94.81272	2.239585	up_reg	9
CENPK	Q9BS16	2	0	3	0.253	0.599	1	81.70731	3.365918	up_reg	50
HOMER2	Q9NSB8	2	1521	3	0.431	0.599	2	89.11372	3.173158	up_reg	101
C1QA	P02745	2	1659	2	0.216	0.597	1	82.87227	2.309558	up_reg	313
RCOR2	Q8IZ40	2	0	1	0.110	0.597	1	68.12330	3.046027	up_reg	65
UNC5B	Q8IZJ1	2	6797	4	0.216	0.597	1	77.98145	2.185793	up_reg	231
APOBEC3B	Q9UH17	2	0	1	0.283	0.593	1	88.33103	4.139712	up_reg	399
B3GNT2	Q9NY97	2	0	1	0.183	0.592	1	91.28206	2.353972	up_reg	44
KCNJ11	Q14654	2	0	1	0.126	0.592	1	84.56523	2.949554	up_reg	1019
RYR1	P21817	2	1899	4	0.190	0.592	1	83.96940	3.086482	up_reg	7993
CXCR3	P49682	2	1658	3	0.210	0.590	1	80.64541	4.557329	up_reg	4275
IFI44L	Q53G44	2	1520	3	0.257	0.590	1	86.36570	2.148762	up_reg	185
LRP2	P98164	2	761	2	0.244	0.590	1	81.82381	4.927297	up_reg	452
CASP8	Q14790	2	5020	5	0.223	0.589	2	81.49031	2.275285	up_reg	5488
OAS2	P29728	19	2	3	0.270	0.588	1	87.74127	4.206419	up_reg	278
UBASH3B	Q8TF42	2	0	1	0.138	0.588	2	85.36864	2.937062	up_reg	54
CXCR4	P61073	2	10567	8	0.122	0.585	1	82.80839	3.415298	up_reg	15921
FBN2	P35556	12	7	3	0.118	0.585	1	70.32078	2.521524	up_reg	313
BCL11A	Q9H165	2	0	1	0.176	0.584	3	52.46475	5.681517	up_reg	706
NRARP	Q7Z6K4	2	1520	2	0.142	0.584	1	82.92880	3.105494	up_reg	46
RACGAP1	Q9H0H5	2	1421	5	0.133	0.584	2	69.86318	3.466668	up_reg	173
DSP	P15924	2	2832	2	0.224	0.581	1	80.17210	4.716943	up_reg	5445
H4C3	P62805	2	0	1	0.336	0.581	1	90.43752	6.938438	up_reg	4
H4C8	P62805	2	5828	7	0.336	0.581	1	90.43752	2.770586	up_reg	3
H4C9	P62805	2	13910	7	0.336	0.581	1	90.43752	4.248213	up_reg	1
STAT1	P42224	2	28968	10	0.247	0.581	2	88.26074	2.024616	up_reg	12059
CA9	Q16790	2	761	2	0.253	0.580	2	76.98377	4.198252	up_reg	2015
NOS1AP	O75052	2	0	1	0.211	0.579	1	66.16135	2.421510	up_reg	221
HLA-DRA	A0A0G2JMH6	2	0	4	0.196	0.578	1	89.93541	3.994244	up_reg	1221
SIGLEC14	Q08ET2	2	0	1	0.311	0.576	1	83.53957	2.119134	up_reg	49
CENPE	Q02224	2	1501	4	0.235	0.575	2	73.06951	2.847355	up_reg	436
RAD54B	Q9Y620	2	0	1	0.092	0.573	1	71.80594	2.894284	up_reg	91
GMNC	A6NCL1	2	0	1	0.280	0.572	1	59.65300	6.567087	up_reg	40
GPSM3	Q9Y4H4	2	0	1	0.281	0.570	1	71.62680	2.087401	up_reg	18
LTF	P02788	2	2076	3	0.410	0.569	1	95.06001	5.560156	up_reg	1484
FCGR1A	P12314	2	26802	5	0.350	0.568	2	84.96186	3.117302	up_reg	253
HLA-DQA2	P01906	2	761	6	0.146	0.568	1	89.47761	4.305408	up_reg	88
ELMO3	Q96BJ8	2	0	1	0.169	0.567	2	89.19677	3.013380	up_reg	22
CLDN6	P56747	2	4049	7	0.114	0.566	1	80.73011	12.449902	up_reg	114
FBN2	P35556	12	7	3	0.126	0.565	1	75.59208	2.521524	up_reg	313
GZMA	P12544	2	0	1	0.340	0.564	2	91.46294	2.555949	up_reg	557
MARVELD2	Q8N4S9	2	3133	5	0.305	0.564	1	67.20563	5.592913	up_reg	78
P2RY6	Q15077	43	0	1	0.257	0.563	1	85.89765	4.546917	up_reg	35
E2F8	A0AVK6	2	0	1	0.140	0.562	1	53.69316	6.360635	up_reg	151
PACSIN1	Q9BY11	2	761	2	0.285	0.562	1	85.39394	2.524601	up_reg	88
RPS6KA1	Q15418	2	3340	3	0.060	0.562	3	77.46253	2.996836	up_reg	451
ENHO	Q6UWT2	27	0	1	0.408	0.561	2	75.10782	3.532277	up_reg	183
RSPO4	Q2I0M5	37	0	2	0.197	0.559	1	78.73711	3.739053	up_reg	61
DNAH5	Q8TE73	24	0	1	0.380	0.558	1	86.10504	3.828651	up_reg	183
DSCC1	Q9BVC3	2	0	1	0.206	0.558	1	92.16572	2.243598	up_reg	20
KIF2C	Q99661	2	8668	7	0.070	0.558	2	74.65762	4.503661	up_reg	295
ZBP1	Q9H171	2	0	1	0.155	0.556	1	55.84276	4.315149	up_reg	389
TK1	P04183	2	28	2	0.284	0.554	2	82.30998	5.569907	up_reg	778
MAP4K1	Q92918	2	0	1	0.100	0.553	2	69.28828	2.859794	up_reg	52
NGEF	Q8N5V2	2	0	1	0.181	0.553	1	72.01310	2.849246	up_reg	50
EXO1	Q9UQ84	2	0	2	0.203	0.552	1	63.63935	4.665404	up_reg	924
SPN	P16150	2	0	1	0.297	0.552	1	53.31901	2.356560	up_reg	3261
UBE2S	Q16763	2	77901	9	0.168	0.552	1	81.85029	2.769728	up_reg	116
ALDH3B1	P43353	5	0	2	0.048	0.550	1	96.26882	2.749792	up_reg	38
MCM10	Q7L590	2	0	5	0.080	0.549	2	66.88891	4.376528	up_reg	231
PRKCQ	Q04759	2	0	1	0.202	0.549	2	79.85454	2.711625	up_reg	721
BARX2	Q9UMQ3	2	0	1	0.238	0.548	1	66.35156	7.021298	up_reg	61
TNFRSF9	Q07011	2	761	2	0.306	0.548	2	81.76231	5.502102	up_reg	554
ERCC6L	Q2NKX8	2	761	2	0.048	0.546	1	62.79458	2.571255	up_reg	62
ITGA3	P26006	2	2794	5	0.183	0.545	2	84.16933	2.090433	up_reg	228
MUC5B	Q9HC84	2	1020	3	1.024	0.544	1	81.82964	5.737039	up_reg	1207
HLA-DMB	P28068	2	0	2	0.451	0.541	1	89.04596	2.973875	up_reg	427
MICB	Q29980	2	117	2	0.152	0.538	1	78.97880	2.653896	up_reg	735
PTPN3	P26045	2	0	1	0.087	0.538	1	73.60570	2.860009	up_reg	82
CITED4	Q96RK1	2	761	2	0.279	0.537	1	61.06457	3.902872	up_reg	42
ECT2	Q9H8V3	2	463	3	0.116	0.537	1	71.66219	4.589366	up_reg	384
RYR1	P21817	2	1899	4	0.107	0.537	2	84.48735	3.086482	up_reg	7993
TTC30B	Q8N4P2	55	0	1	0.170	0.535	2	93.27146	2.933139	up_reg	4
ALOX5AP	P20292	7	0	1	0.299	0.534	1	89.60768	2.082130	up_reg	517
THEM6	Q8WUY1	2	0	1	0.187	0.534	1	94.93291	3.578714	up_reg	6
SMC4	Q9NTJ3	2	4021	6	0.294	0.533	3	81.89970	2.074392	up_reg	175
MLF1	P58340	2	799	4	0.247	0.532	1	65.94371	2.278928	up_reg	110
NDC80	O14777	2	2922	3	0.161	0.532	2	78.60958	4.044795	up_reg	592
LSR	Q86X29	2	4740	5	0.029	0.531	2	57.32796	5.010835	up_reg	1449
EPPK1	P58107	2	0	1	0.206	0.530	2	83.08865	6.941326	up_reg	38
KRT18	P05783	2	5320	3	0.125	0.530	1	80.29975	5.341706	up_reg	409
LINGO1	Q96FE5	2	0	1	0.222	0.530	2	86.97018	3.398463	up_reg	268
TYMS	P04818	2	0	2	0.380	0.529	1	94.13606	2.197956	up_reg	818
CGN	Q9P2M7	2	0	1	0.153	0.528	1	70.80985	2.903039	up_reg	1290
IL2RB	P14784	2	377	2	0.064	0.528	1	65.81703	3.612277	up_reg	374
EGFL6	Q8IUX8	26	0	1	0.125	0.526	1	67.15563	6.860705	up_reg	84
SCNN1A	P37088	2	0	1	0.225	0.525	1	75.79274	5.496125	up_reg	300
CENPF	P49454	2	10672	3	0.399	0.524	2	72.41199	4.302935	up_reg	385
GNGT1	P63211	2	9443	6	0.318	0.524	1	88.83912	3.959000	up_reg	29
RBBP8	Q99708	2	4708	8	0.355	0.524	1	53.50791	2.260842	up_reg	287
NELL2	Q99435	14	0	1	0.254	0.523	1	80.32717	2.349571	up_reg	103
TM4SF1	P30408	2	0	1	0.246	0.523	1	81.27962	2.530357	up_reg	151
CDK5	Q00535	2	4541	5	0.253	0.522	1	91.44164	2.814439	up_reg	3067
ESRRG	P62508	2	0	1	0.247	0.522	1	76.18379	3.288085	up_reg	338
MCM2	P49736	2	0	2	0.139	0.522	3	76.52259	2.384586	up_reg	1556
PKM	P14618	2	3037	5	0.224	0.522	2	96.78672	2.561725	up_reg	1019
LAIR1	Q6GTX8	2	174	2	0.416	0.521	1	71.90481	2.172930	up_reg	216
PTPRF	P10586	2	0	1	0.303	0.521	3	82.86021	2.388058	up_reg	139
KCTD1	Q719H9	2	0	1	0.380	0.519	1	87.09265	3.190517	up_reg	35
S100A4	P26447	2	7702	4	0.313	0.516	1	85.18673	3.072037	up_reg	1705
CENPM	Q9NSP4	2	439	4	0.181	0.514	1	89.76468	4.526135	up_reg	49
KRT15	P19012	2	4	4	0.359	0.513	1	77.14245	3.112879	up_reg	229
MPZL3	Q6UWV2	40	0	1	0.289	0.513	1	80.77116	2.509616	up_reg	25
RYR1	P21817	2	1899	4	0.269	0.513	1	80.35160	3.086482	up_reg	7993
EMB	Q6PCB8	2	2277	2	0.381	0.512	1	78.47557	2.398641	up_reg	3502
PCDH19	Q8TAB3	2	0	1	0.156	0.512	1	68.74772	2.531005	up_reg	242
DNAH3	Q8TD57	24	0	1	0.407	0.511	1	85.57752	3.642484	up_reg	16
DTL	Q9NZJ0	2	0	1	0.101	0.511	2	63.43932	4.651305	up_reg	625
TNFRSF13C	Q96RJ3	2	388	2	0.223	0.511	1	64.47587	2.730865	up_reg	371
ASPM	Q8IZT6	2	8922	4	0.281	0.507	2	68.95596	4.312243	up_reg	510
DNAH3	Q8TD57	24	0	1	0.093	0.507	1	88.96404	3.642484	up_reg	16
MUC16	Q8WXI7	2	1521	3	0.129	0.507	3	61.67421	8.476038	up_reg	1352
PNP	P00491	46	1	2	0.189	0.507	1	94.05180	2.680894	up_reg	6777
PTPN6	P29350	2	2507	6	0.243	0.507	1	86.41216	3.217645	up_reg	1532
KIF14	Q15058	2	5312	10	0.127	0.506	1	66.04636	4.471441	up_reg	163
ITGB4	P16144	2	8018	6	0.154	0.505	1	69.97733	3.972681	up_reg	363
DSP	P15924	2	2832	2	0.580	0.504	2	77.45712	4.716943	up_reg	5445
PTTG1	O95997	2	3399	3	0.339	0.504	1	64.54399	5.620004	up_reg	437
CDKN2A	P42771	2	761	3	0.396	0.503	2	75.59437	8.463693	up_reg	13656
LPAR3	Q9UBY5	2	0	1	0.018	0.503	1	81.89258	4.654211	up_reg	129
CDH6	P55285	2	3554	3	0.178	0.502	1	78.76359	5.541725	up_reg	108
ERBB3	P21860	2	19657	7	0.108	0.502	1	72.82537	4.895964	up_reg	2709
EPPK1	P58107	2	0	1	0.114	0.501	1	79.25178	6.941326	up_reg	38
GIPC1	O14908	2	0	1	0.347	0.501	1	81.65762	2.472014	up_reg	174
CXCL1	P09341	2	1755	4	0.207	0.499	1	82.27114	3.026079	up_reg	6221
EVPL	Q92817	2	0	1	0.174	0.499	1	73.17542	5.384071	up_reg	34
KIF23	Q02241	2	5487	6	0.314	0.498	1	73.07353	3.446904	up_reg	207
PPARGC1B	Q86YN6	2	0	1	0.075	0.497	1	50.96161	2.110510	up_reg	252
IL12RB1	P42701	2	0	1	0.192	0.495	1	77.25548	2.276120	up_reg	347
CYRIB	Q9NUQ9	2	0	1	0.134	0.494	1	92.17381	2.720870	up_reg	15
EPPK1	P58107	2	0	1	0.112	0.491	2	82.39167	6.941326	up_reg	38
FOXP3	Q9BZS1	2	761	2	0.090	0.491	1	58.06645	2.948779	up_reg	21309
FBP1	P09467	3	1	2	0.373	0.490	1	94.36528	3.028902	up_reg	548
WNT7A	O00755	2	761	2	0.309	0.489	1	88.75607	9.734620	up_reg	673
FGFR3	P22607	2	2641	4	0.127	0.488	1	75.36964	3.476785	up_reg	3416
ANXA3	P12429	2	0	1	0.484	0.487	1	96.34132	4.071198	up_reg	190
CENPE	Q02224	2	1501	4	0.168	0.487	1	72.31956	2.847355	up_reg	436
CENPF	P49454	2	10672	3	0.437	0.484	2	70.99553	4.302935	up_reg	385
CDCA8	Q53HL2	2	6045	6	0.388	0.483	1	68.78919	4.987197	up_reg	205
DNAH5	Q8TE73	24	0	1	0.261	0.481	1	83.92766	3.828651	up_reg	183
ITGB6	P18564	2	0	1	0.064	0.481	1	83.51907	5.417491	up_reg	168
MRPL13	Q9BYD1	2	2181	4	0.371	0.481	1	93.49656	2.310295	up_reg	32
MUC5B	Q9HC84	2	1020	3	0.161	0.481	1	60.93242	5.737039	up_reg	1207
TNNC1	P63316	2	0	1	0.394	0.480	1	79.95947	2.859371	up_reg	127
CD86	P42081	2	4201	4	0.351	0.479	1	79.80962	2.860159	up_reg	12042
WNT2	P09544	2	688	2	0.340	0.478	1	88.00264	2.283292	up_reg	612
DNAH5	Q8TE73	24	0	1	0.239	0.477	3	83.80640	3.828651	up_reg	183
LEF1	Q9UJU2	2	4131	5	0.140	0.477	1	57.83920	3.139927	up_reg	2086
OLR1	P78380	2	0	1	0.388	0.476	1	87.40709	4.414247	up_reg	1066
CD200R1	Q8TD46	2	0	1	0.414	0.475	1	76.65146	2.587670	up_reg	259
SH3BGRL3	Q9H299	44	0	1	0.301	0.475	1	96.43171	2.275968	up_reg	34
CD38	P28907	2	2701	2	0.290	0.474	1	91.07150	2.603605	up_reg	9643
NCF1	P14598	2	1234	2	0.241	0.472	1	83.56633	2.397018	up_reg	369
CDK1	P06493	2	17675	13	0.514	0.471	1	89.31551	4.500461	up_reg	5957
LCK	P06239	2	54987	19	0.188	0.471	1	84.33331	2.329222	up_reg	3794
FBN3	Q75N90	12	0	1	0.191	0.470	1	74.68523	5.054065	up_reg	53
NDUFS8	O00217	2	0	1	0.547	0.470	1	89.19101	2.656440	up_reg	70
DEPDC1B	Q8WUY9	2	444	3	0.107	0.469	1	77.36351	4.803039	up_reg	54
CD52	P31358	2	0	1	0.352	0.466	1	68.58155	2.633993	up_reg	1238
TFF3	Q07654	2	761	2	0.405	0.466	1	80.13800	2.167937	up_reg	1057
EPPK1	P58107	2	0	1	0.303	0.465	1	81.46403	6.941326	up_reg	38
EPPK1	P58107	2	0	1	0.325	0.465	1	80.08462	6.941326	up_reg	38
EPPK1	P58107	2	0	1	0.164	0.464	1	78.69683	6.941326	up_reg	38
MUC5B	Q9HC84	2	1020	3	0.316	0.464	1	54.54405	5.737039	up_reg	1207
OCLN	Q16625	2	4018	7	0.030	0.464	1	65.47618	3.942788	up_reg	1993
CNKSR1	Q969H4	2	0	1	0.212	0.463	1	68.49088	2.403831	up_reg	35
MUC16	Q8WXI7	2	1521	3	0.089	0.463	1	74.65565	8.476038	up_reg	1352
E2F3	O00716	2	761	2	-0.002	0.462	1	61.41248	2.643044	up_reg	789
SPON1	Q9HCB6	2	761	2	0.074	0.461	1	77.42394	3.386911	up_reg	119
DNAH3	Q8TD57	24	0	1	0.143	0.459	1	85.20082	3.642484	up_reg	16
FAM83D	Q9H4H8	2	0	1	0.140	0.459	1	64.42717	5.053814	up_reg	58
OAS1	P00973	19	0	2	0.310	0.455	1	84.21378	3.083827	up_reg	681
CLIC5	Q9NZA1	2	760	2	0.184	0.454	1	68.21008	5.435746	up_reg	79
CEBPA	P49715	2	18094	5	0.467	0.453	1	63.67368	3.364331	up_reg	1906
RAB3IP	Q96QF0	48	1	2	0.090	0.453	1	72.31525	2.494769	up_reg	30
CENPF	P49454	2	10672	3	0.416	0.452	1	70.50561	4.302935	up_reg	385
S100A1	P23297	2	1966	2	0.469	0.452	2	82.78688	5.000700	up_reg	521
DOK7	Q18PE1	2	0	1	0.150	0.450	1	66.42315	5.786555	up_reg	193
NECTIN4	Q96NY8	2	761	2	0.112	0.450	1	78.89692	6.633982	up_reg	334
EPPK1	P58107	2	0	1	0.164	0.448	1	81.31179	6.941326	up_reg	38
FBN2	P35556	12	7	3	0.146	0.448	1	73.40911	2.521524	up_reg	313
LAMA5	O15230	2	3467	4	0.132	0.448	1	83.31297	2.244719	up_reg	154
BLNK	Q8WV28	2	80581	4	0.308	0.447	1	64.71740	2.938435	up_reg	282
CXCL14	O95715	2	2123	5	0.298	0.447	1	85.46693	2.064284	up_reg	483
DEPDC1	Q5TB30	2	0	1	0.111	0.445	1	61.05036	5.973836	up_reg	91
NEIL3	Q8TAT5	2	1223	6	0.015	0.445	1	70.00855	5.418772	up_reg	151
ZNF217	O75362	2	6359	7	0.240	0.445	1	50.34735	2.073407	up_reg	219
PI3	P19957	2	58	2	0.417	0.443	1	71.76906	7.675165	up_reg	9625
ALOX5	P09917	7	0	1	0.355	0.442	1	97.15666	2.088381	up_reg	521
GRHL2	Q6ISB3	33	0	1	0.092	0.442	1	67.86823	7.179971	up_reg	231
MSX1	P28360	2	1056	2	0.339	0.442	1	65.80064	2.501717	up_reg	1214
MYH14	Q7Z406	2	0	1	0.245	0.442	1	74.65097	6.665417	up_reg	115
GINS3	Q9BRX5	2	2215	4	0.238	0.441	1	88.16138	2.227008	up_reg	28
IKBKE	Q14164	2	123	2	0.192	0.440	1	88.66232	2.971049	up_reg	1238
PPP1CA	P62136	2	17077	14	0.206	0.440	1	91.55269	2.763584	up_reg	98
PCDH7	O60245	2	0	1	0.174	0.439	1	76.89920	2.341810	up_reg	114
KRT5	P13647	2	0	4	0.423	0.438	1	68.77450	4.040272	up_reg	612
KIF18B	Q86Y91	2	764	11	0.200	0.437	1	62.74387	5.536292	up_reg	74
WAS	P42768	2	2279	3	0.258	0.437	1	70.12989	2.016246	up_reg	0
NAA38	Q9BRA0	2	0	1	0.488	0.435	1	79.30929	2.165583	up_reg	16
CA12	O43570	2	0	1	0.413	0.434	1	88.39335	3.797709	up_reg	388
COL23A1	Q86Y22	1	0	2	0.185	0.433	1	60.28518	4.830819	up_reg	30
CCL5	P13501	2	9296	3	0.141	0.432	1	89.33505	3.279413	up_reg	8493
MYO5B	Q9ULV0	41	0	1	0.304	0.432	1	75.50398	3.621753	up_reg	185
TES	Q9UGI8	2	0	1	0.196	0.431	1	86.49349	2.394874	up_reg	8760
SMKR1	H3BMG3	2	0	1	0.229	0.430	1	70.64355	5.083228	up_reg	1
STXBP2	Q15833	2	761	2	0.122	0.430	1	90.53373	2.772280	up_reg	160
RYR1	P21817	2	1899	4	0.093	0.428	1	84.72206	3.086482	up_reg	7993
FOXP4	Q8IVH2	2	0	1	0.159	0.427	1	59.23848	2.392759	up_reg	143
TNFRSF4	P43489	2	0	1	0.295	0.427	1	77.22429	2.183879	up_reg	644
GATA3	P23771	2	29626	9	0.110	0.426	1	58.31754	3.618532	up_reg	5363
HOXB6	P17509	2	0	3	0.098	0.426	1	66.54839	5.256411	up_reg	118
EPPK1	P58107	2	0	1	0.320	0.425	1	79.71663	6.941326	up_reg	38
ORC6	Q9Y5N6	2	4900	4	0.216	0.425	1	81.54463	3.385301	up_reg	101
IFIT2	P09913	2	0	1	0.301	0.424	1	88.96310	2.135232	up_reg	254
CKS1B	P61024	2	9359	3	0.172	0.423	1	92.17249	2.929388	up_reg	191
CTNNA2	P26232	2	0	1	0.082	0.423	1	80.50284	4.876683	up_reg	94
PLS1	Q14651	2	0	2	0.067	0.423	1	87.84443	4.693588	up_reg	352
RGS1	Q08116	2	0	1	0.315	0.422	1	81.96646	2.074463	up_reg	310
BICDL2	A1A5D9	11	0	1	0.351	0.415	1	80.82586	5.705336	up_reg	0
EPPK1	P58107	2	0	1	0.175	0.414	2	81.08339	6.941326	up_reg	38
CDKN3	Q16667	2	0	1	0.472	0.413	1	91.05949	4.403471	up_reg	184
GAPDH	P04406	2	8828	5	0.345	0.413	1	98.17071	2.454683	up_reg	8509
JPH1	Q9HDC5	2	0	1	0.144	0.413	1	66.01235	2.552469	up_reg	27
KNSTRN	Q9Y448	2	0	1	0.402	0.413	1	68.64854	2.082946	up_reg	35
OAS3	Q9Y6K5	19	0	2	0.107	0.413	2	86.81560	2.988047	up_reg	199
LLGL2	Q6P1M3	2	761	2	0.114	0.412	2	85.39241	2.400335	up_reg	46
TPD52	P55327	2	761	5	0.350	0.412	1	68.17637	4.269727	up_reg	183
GNLY	P22749	2	761	2	0.379	0.410	1	78.38773	2.553860	up_reg	401
OTUB2	Q96DC9	2	0	1	0.314	0.410	1	94.26903	2.133800	up_reg	43
NRG4	Q8WWG1	2	0	3	0.403	0.409	1	78.48852	2.336379	up_reg	130
RASSF7	Q02833	2	0	1	0.307	0.409	1	74.57045	3.298786	up_reg	42
DNAH5	Q8TE73	24	0	1	0.170	0.408	1	87.45737	3.828651	up_reg	183
CCL20	P78556	2	2052	2	0.403	0.405	1	89.38489	5.283080	up_reg	2596
BUB1	O43683	2	1521	3	0.138	0.403	1	64.12427	4.789490	up_reg	1284
MUC16	Q8WXI7	2	1521	3	0.196	0.403	1	73.85441	8.476038	up_reg	1352
ZC2HC1C	Q53FD0	55	0	1	0.370	0.403	1	61.17503	2.306638	up_reg	2
FBN3	Q75N90	12	0	1	0.179	0.400	1	75.00891	5.054065	up_reg	53
MRPL14	Q6P1L8	2	231	4	0.335	0.400	1	86.22027	2.510977	up_reg	12
TACC3	Q9Y6A5	2	727	2	0.259	0.400	1	58.34000	3.743070	up_reg	369
GRHL1	Q9NZI5	33	0	1	0.206	0.399	0	68.95769	3.061285	up_reg	64
HLA-DRB1	P01911	2	4530	4	0.309	0.398	0	89.12497	3.221560	up_reg	10656
MRPL15	Q9P015	2	0	2	0.439	0.396	0	91.01003	2.252783	up_reg	21
DARS2	Q6PI48	23	0	1	0.102	0.394	0	88.75458	2.268401	up_reg	103
SORT1	Q99523	2	2539	6	0.176	0.394	0	83.49614	2.686299	up_reg	283
BOP1	Q14137	13	0	1	0.149	0.393	0	80.78432	2.165984	up_reg	120
MAFB	Q9Y5Q3	2	1384	3	0.207	0.393	0	64.85064	2.002627	up_reg	701
OASL	Q15646	2	0	2	0.340	0.392	0	92.28700	5.308283	up_reg	267
EPPK1	P58107	2	0	1	0.229	0.391	0	80.87318	6.941326	up_reg	38
CCL2	P13500	2	6612	3	0.274	0.389	0	87.56294	2.248695	up_reg	20922
SYNGR3	O43761	2	0	1	0.202	0.389	0	80.73087	2.967295	up_reg	15
SLC7A1	P30825	2	1521	3	0.129	0.387	0	81.62643	2.506855	up_reg	219
CEP55	Q53EZ4	2	640	2	0.284	0.386	0	82.79305	5.920805	up_reg	274
FBXL16	Q8N461	31	0	1	0.345	0.386	0	84.45983	4.344689	up_reg	15
MARS2	Q96GW9	4	0	1	0.093	0.386	0	89.64912	2.313493	up_reg	31
AP1S3	Q96PC3	2	11076	13	0.308	0.385	0	93.25617	3.118487	up_reg	40
KCNQ1	P51787	2	1520	2	0.165	0.385	0	68.84458	2.709769	up_reg	2537
CENPF	P49454	2	10672	3	0.219	0.384	0	70.83409	4.302935	up_reg	385
HP	P00738	2	0	1	0.249	0.384	0	86.65695	3.617985	up_reg	99196
PTPRJ	Q12913	2	0	1	0.406	0.384	0	78.57151	2.285213	up_reg	229
RYR1	P21817	2	1899	4	0.093	0.383	0	80.54768	3.086482	up_reg	7993
UBE2T	Q9NPD8	2	0	1	0.273	0.383	0	86.02709	5.344372	up_reg	147
KRT23	Q9C075	2	1409	6	0.182	0.382	0	78.43096	7.803255	up_reg	48
LSM4	Q9Y4Z0	2	761	2	0.486	0.382	0	77.63958	2.319798	up_reg	62
TEKT2	Q9UIF3	2	0	6	0.320	0.382	0	91.10427	3.432483	up_reg	16
MMP7	P09237	2	2130	3	0.296	0.381	0	87.58781	8.418438	up_reg	3046
HLA-DQA1	P01909	2	0	6	0.385	0.380	0	88.71415	4.559819	up_reg	1989
MZB1	Q8WU39	29	0	1	0.198	0.380	0	84.76435	3.553878	up_reg	69
EIF4EBP1	Q13541	2	0	1	0.320	0.379	0	71.29362	2.070414	up_reg	1560
RRM2	P31350	2	0	1	0.276	0.377	0	80.12601	5.527053	up_reg	906
ZNF726	A6NNF4	56	0	1	0.407	0.377	0	70.98692	2.195829	up_reg	4
CDCA5	Q96FF9	2	0	1	0.258	0.376	0	63.50505	4.692774	up_reg	156
RFXANK	O14593	2	0	1	0.338	0.374	0	79.70517	2.042703	up_reg	87
KIF1A	Q12756	2	0	11	0.106	0.373	0	71.01825	4.710262	up_reg	351
SPC24	Q8NBT2	2	0	1	0.345	0.372	0	91.39337	4.999440	up_reg	79
DDAH1	O94760	2	0	1	0.378	0.370	0	95.89648	2.198679	up_reg	338
EPPK1	P58107	2	0	1	0.118	0.370	0	82.67139	6.941326	up_reg	38
PIF1	Q9H611	2	0	1	0.062	0.368	0	77.97936	2.843531	up_reg	476
PIERCE1	Q5BN46	2	0	6	0.223	0.365	0	76.89413	3.026062	up_reg	6
TNNI1	P19237	2	1141	3	0.252	0.365	0	78.08491	4.029660	up_reg	90
SEMA3A	Q14563	2	3032	2	0.234	0.363	0	84.47667	3.102679	up_reg	1503
GNL3L	Q9NVN8	13	0	1	0.138	0.362	0	72.84667	3.254326	up_reg	26
TYROBP	O43914	2	4887	4	0.285	0.361	0	64.54930	3.691863	up_reg	602
ASPM	Q8IZT6	2	8922	4	0.161	0.360	0	63.08517	4.312243	up_reg	510
CLDN4	O14493	2	2764	6	0.511	0.360	0	84.52154	7.966261	up_reg	627
GRB7	Q14451	2	0	1	0.214	0.360	0	78.88878	6.167946	up_reg	309
ASPM	Q8IZT6	2	8922	4	0.271	0.359	0	70.40001	4.312243	up_reg	510
BID	P55957	2	0	1	0.136	0.357	0	62.45273	2.048675	up_reg	19500
COX7B	P24311	2	0	2	0.404	0.355	0	90.27638	2.360595	up_reg	50
FCGR2B	P31994	2	0	1	0.421	0.355	0	79.03060	2.783225	up_reg	591
NUDT14	O95848	2	0	1	0.254	0.354	0	94.66943	2.521537	up_reg	7
CENPW	Q5EE01	2	0	4	0.310	0.353	0	89.69919	3.831944	up_reg	60
KIFC1	Q9BW19	2	2554	7	0.202	0.353	0	77.88326	3.454857	up_reg	186
MISP	Q8IVT2	2	1139	2	0.227	0.353	0	54.69582	5.997961	up_reg	192
CADM3	Q8N126	2	0	1	0.379	0.350	0	84.61009	2.432258	up_reg	41
RUNX3	Q13761	2	9057	5	0.403	0.350	0	62.21557	4.881702	up_reg	1560
VAMP8	Q9BV40	2	3785	5	0.286	0.350	0	90.45868	4.647834	up_reg	317
CADM1	Q9BY67	2	1434	3	0.332	0.349	0	81.61015	2.022739	up_reg	579
CTSS	P25774	2	0	1	0.287	0.348	0	94.54174	2.821640	up_reg	564
RABIF	P47224	2	0	1	0.330	0.348	0	89.03728	2.438201	up_reg	29
FTH1	P02794	2	0	1	0.354	0.347	0	95.76727	2.083195	up_reg	545
ASF1B	Q9NVP2	2	750	3	0.391	0.346	0	85.64720	5.643420	up_reg	113
ENKUR	Q8TC29	2	0	5	0.369	0.346	0	87.21706	2.841760	up_reg	12
GREM1	O60565	12	0	1	0.032	0.346	0	73.24474	2.646893	up_reg	586
DNAH5	Q8TE73	24	0	1	0.497	0.345	0	84.07641	3.828651	up_reg	183
ESCO2	Q56NI9	2	0	1	0.462	0.344	0	58.41527	4.684359	up_reg	136
MUC16	Q8WXI7	2	1521	3	0.102	0.344	0	76.30687	8.476038	up_reg	1352
PPP1R16B	Q96T49	2	0	1	0.190	0.344	0	70.84716	2.196990	up_reg	45
RPL39L	Q96EH5	2	0	1	0.319	0.343	0	94.09941	3.915386	up_reg	19
SEMA3F	Q13275	2	0	1	0.253	0.342	0	84.11920	3.717983	up_reg	283
FCGR3A	P08637	2	622	3	0.351	0.341	0	85.63872	2.760408	up_reg	763
PRKCI	P41743	2	38	2	0.145	0.340	0	82.48188	2.360984	up_reg	118
JCHAIN	P01591	35	0	1	0.320	0.338	0	87.07085	3.236821	up_reg	219
DSP	P15924	2	2832	2	0.165	0.337	0	77.42383	4.716943	up_reg	5445
RYR1	P21817	2	1899	4	0.093	0.337	0	82.13187	3.086482	up_reg	7993
CENPF	P49454	2	10672	3	0.173	0.336	0	71.95028	4.302935	up_reg	385
EPPK1	P58107	2	0	1	0.491	0.336	0	81.56797	6.941326	up_reg	38
PDLIM1	O00151	2	3755	2	0.426	0.336	0	70.20826	2.021676	up_reg	70
SERPINA1	P01009	2	20309	6	0.431	0.336	0	89.00521	4.107159	up_reg	1052
LAMTOR2	Q9Y2Q5	2	0	1	0.338	0.335	0	91.48972	2.013323	up_reg	73
TONSL	Q96HA7	2	0	3	0.187	0.335	0	76.48871	2.768622	up_reg	54
LRP2	P98164	2	761	2	0.423	0.334	0	79.91038	4.927297	up_reg	452
EPPK1	P58107	2	0	1	0.203	0.333	0	82.96788	6.941326	up_reg	38
EPPK1	P58107	2	0	1	0.151	0.330	0	82.02849	6.941326	up_reg	38
HLA-DRB5	Q30154	2	206	6	0.385	0.330	0	88.27784	2.841964	up_reg	548
HOXB5	P09067	2	3032	4	0.277	0.330	0	63.73337	5.327041	up_reg	195
PSMB3	P49720	2	0	1	0.327	0.330	0	97.37889	2.223922	up_reg	28
MYCN	P04198	2	6049	4	0.286	0.329	0	61.81702	2.589804	up_reg	3302
TNFAIP6	P98066	2	1198	2	0.207	0.328	0	82.64910	2.971830	up_reg	536
BCL2A1	Q16548	2	0	1	0.333	0.327	0	87.41244	2.485455	up_reg	273
MFAP5	Q13361	12	0	1	-0.012	0.327	0	65.71101	3.343997	up_reg	81
CKMT1A	P12532	8	0	1	0.049	0.325	0	90.05943	6.417662	up_reg	20
CKMT1B	P12532	8	0	1	0.049	0.325	0	90.05943	4.787301	up_reg	16
CLSPN	Q9HAW4	2	7028	7	0.285	0.322	0	51.81036	5.405931	up_reg	151
MUC5B	Q9HC84	2	1020	3	0.121	0.321	0	61.04555	5.737039	up_reg	1207
CLDN9	O95484	2	0	6	0.387	0.320	0	81.18086	7.555719	up_reg	51
ZWINT	O95229	2	4	2	0.268	0.320	0	79.45827	3.872467	up_reg	129
GINS2	Q9Y248	2	0	2	0.258	0.318	0	93.40448	2.817382	up_reg	85
RIPK3	Q9Y572	2	0	1	0.217	0.318	0	67.61724	2.151159	up_reg	1999
EME1	Q96AY2	2	1520	2	0.155	0.315	0	67.90349	2.216719	up_reg	191
EPPK1	P58107	2	0	1	0.246	0.315	0	79.72240	6.941326	up_reg	38
RYR1	P21817	2	1899	4	0.089	0.315	0	81.69913	3.086482	up_reg	7993
TNFSF13B	Q9Y275	2	761	4	0.316	0.307	0	79.05813	2.662063	up_reg	1362
MUC16	Q8WXI7	2	1521	3	0.065	0.305	0	75.39936	8.476038	up_reg	1352
WNT11	O96014	2	0	1	0.355	0.304	0	90.30817	2.266810	up_reg	623
GMIP	Q9P107	2	0	1	0.172	0.303	0	70.24573	2.022512	up_reg	34
LRP2	P98164	2	761	2	0.155	0.303	0	79.58308	4.927297	up_reg	452
RTN4R	Q9BZR6	2	761	2	0.240	0.303	0	77.06296	2.676907	up_reg	339
KIF6	Q6ZMV9	2	0	12	0.091	0.302	0	71.56561	2.593490	up_reg	83
NOL4L	Q96MY1	2	0	1	0.262	0.302	0	62.45976	2.745127	up_reg	11
TP73	O15350	2	892	3	0.199	0.300	0	66.41421	3.196305	up_reg	1569
MELTF	P08582	2	0	1	0.273	0.298	0	89.73721	2.741729	up_reg	38
REC8	O95072	2	0	2	0.349	0.297	0	64.69331	3.247582	up_reg	418
E2F1	Q01094	2	10918	7	0.159	0.295	0	63.73504	2.635547	up_reg	5117
TACSTD2	P09758	2	0	1	0.332	0.294	0	82.22030	6.975909	up_reg	296
MYL11	Q96A32	2	761	2	0.286	0.293	0	84.57639	3.638218	up_reg	0
BEND3	Q5T5X7	2	0	1	0.249	0.292	0	65.37982	2.733342	up_reg	142
CXCL17	Q6UXB2	2	11398	7	0.060	0.292	0	59.53315	7.541358	up_reg	104
SALL4	Q9UJQ4	2	0	1	0.204	0.290	0	51.44781	3.878009	up_reg	846
CD4	P01730	2	3035	4	0.442	0.289	0	85.57181	2.281950	up_reg	186553
FBN3	Q75N90	12	0	1	0.095	0.287	0	73.76318	5.054065	up_reg	53
GINS1	Q14691	2	0	2	0.241	0.287	0	93.30269	3.780438	up_reg	67
MUC5B	Q9HC84	2	1020	3	0.107	0.287	0	72.66008	5.737039	up_reg	1207
SIX1	Q15475	28	2	2	0.184	0.287	0	74.01302	5.368302	up_reg	721
UBE2C	O00762	2	23230	6	0.355	0.286	0	89.69871	6.912778	up_reg	434
PPP1R1B	Q9UD71	2	0	1	0.401	0.285	0	66.04138	2.849180	up_reg	390
CCNE1	P24864	2	4140	5	0.101	0.284	0	79.97658	5.446912	up_reg	1061
KCNQ3	O43525	2	0	2	0.045	0.284	0	57.10836	3.162918	up_reg	527
CXCL9	Q07325	2	4000	3	0.304	0.283	0	87.92398	5.250589	up_reg	3397
PTK6	Q13882	2	5745	4	0.137	0.283	0	89.16695	2.218046	up_reg	248
S100A2	P29034	2	0	1	0.329	0.282	0	87.05777	5.595045	up_reg	304
TTC30A	Q86WT1	55	1	2	0.265	0.280	0	93.50527	2.528791	up_reg	3
DSP	P15924	2	2832	2	0.201	0.279	0	80.86139	4.716943	up_reg	5445
SELPLG	Q14242	2	0	1	0.376	0.279	0	51.08547	2.634270	up_reg	66
TFAP2C	Q92754	2	2279	3	0.181	0.278	0	66.88803	5.774422	up_reg	281
EPHA1	P21709	2	4697	4	0.216	0.277	0	80.64237	4.441436	up_reg	315
PPL	O60437	2	7508	3	0.357	0.276	0	75.60075	2.018881	up_reg	2003
PSMB9	P28065	2	0	1	0.362	0.276	0	91.17994	2.788039	up_reg	173
MSLN	Q13421	2	0	1	0.171	0.275	0	79.08734	7.267283	up_reg	812
LAMA5	O15230	2	3467	4	0.171	0.274	0	83.83144	2.244719	up_reg	154
ULBP3	Q9BZM4	2	0	1	0.341	0.273	0	82.87018	4.365563	up_reg	143
OVGP1	Q12889	2	0	2	0.067	0.271	0	70.75963	2.519934	up_reg	105
CD300A	Q9UGN4	2	0	1	0.291	0.270	0	70.96770	2.052455	up_reg	124
COBL	O75128	2	0	1	0.050	0.270	0	50.28154	2.051585	up_reg	103
SPI1	P17947	2	0	2	0.383	0.269	0	65.99688	2.766086	up_reg	1314
AP1M2	Q9Y6Q5	2	7501	13	0.188	0.268	0	93.09129	8.570288	up_reg	40
LRP2	P98164	2	761	2	0.148	0.268	0	74.88229	4.927297	up_reg	452
ST6GALNAC5	Q9BVH7	3	0	1	0.187	0.268	0	82.09840	2.808701	up_reg	36
IL18	Q14116	2	2672	3	0.438	0.267	0	89.07080	3.642493	up_reg	16116
MUC4	Q99102	2	0	1	0.254	0.266	0	58.53420	3.542323	up_reg	1209
LRP2	P98164	2	761	2	0.249	0.264	0	84.11100	4.927297	up_reg	452
DSG2	Q14126	2	17165	3	0.361	0.262	0	65.83342	2.526737	up_reg	470
IL1B	P01584	2	9795	5	0.104	0.259	0	75.92467	2.915989	up_reg	9812
LCN2	P80188	2	0	1	0.140	0.259	0	91.99169	9.042459	up_reg	3659
AIMP2	Q13155	4	0	1	0.116	0.258	0	81.79153	2.483720	up_reg	94
SH2D2A	Q9NP31	2	761	2	0.085	0.258	0	62.79150	2.625689	up_reg	92
PRICKLE3	O43900	2	0	1	0.183	0.257	0	67.53085	2.181166	up_reg	13
KIF18A	Q8NI77	2	2337	10	0.186	0.256	0	67.74104	4.341757	up_reg	144
FAM167A	Q96KS9	29	0	1	0.247	0.255	0	72.66449	4.356541	up_reg	37
NACC1	Q96RE7	2	0	1	0.205	0.255	0	64.21521	3.382755	up_reg	102
E2F7	Q96AV8	2	1521	3	0.108	0.254	0	51.27249	4.380384	up_reg	224
RYR1	P21817	2	1899	4	0.187	0.254	0	79.11971	3.086482	up_reg	7993
STXBP6	Q8NFX7	52	0	1	0.123	0.254	0	87.12139	2.430172	up_reg	31
LRFN4	Q6PJG9	2	761	2	0.222	0.253	0	78.08724	2.052951	up_reg	20
EPCAM	P16422	2	77	2	0.289	0.252	0	87.50649	7.738423	up_reg	9825
TNNT1	P13805	2	0	2	0.147	0.251	0	74.97393	6.310523	up_reg	141
HDGF	P51858	26	0	1	0.359	0.250	0	68.36683	2.071828	up_reg	328
KCNK15	Q9H427	36	0	1	0.042	0.249	0	79.75423	5.076910	up_reg	19
KRT7	P08729	2	0	4	0.442	0.249	0	75.69421	7.336874	up_reg	692
BANK1	Q8NDB2	2	0	1	0.100	0.248	0	61.61418	3.730736	up_reg	117
CLDN16	Q9Y5I7	2	23	6	0.140	0.247	0	69.10264	9.609066	up_reg	118
BRCA2	P51587	2	32217	9	0.072	0.246	0	55.07728	2.245119	up_reg	14293
CENPF	P49454	2	10672	3	0.328	0.243	0	70.33298	4.302935	up_reg	385
RAD51AP1	Q96B01	2	333	5	0.122	0.242	0	58.79844	4.168726	up_reg	95
FAM181A	Q8N9Y4	2	0	1	0.330	0.241	0	60.50458	8.294660	up_reg	11
LILRB4	Q8NHJ6	2	0	2	0.423	0.240	0	66.70081	3.936863	up_reg	208
CABLES1	Q8TDN4	2	0	1	0.107	0.239	0	57.81542	2.363657	up_reg	61
FKBP1C	Q5VVH2	2	0	1	0.363	0.239	0	95.38909	2.614579	up_reg	1
TNFRSF8	P28908	2	526	2	0.196	0.238	0	61.29206	2.047671	up_reg	72
FBN2	P35556	12	7	3	0.059	0.237	0	72.51160	2.521524	up_reg	313
VGLL1	Q99990	2	0	1	0.305	0.237	0	58.22350	10.261579	up_reg	32
FBN3	Q75N90	12	0	1	0.244	0.236	0	75.06822	5.054065	up_reg	53
KRT14	P02533	2	0	4	0.398	0.236	0	75.92890	3.310309	up_reg	716
NTN1	O95631	2	761	2	0.246	0.236	0	88.71749	3.118007	up_reg	738
MYCL	P12524	11	0	1	0.386	0.235	0	65.02508	7.726211	up_reg	137
CDT1	Q9H211	2	761	3	0.393	0.234	0	74.90779	4.825580	up_reg	656
H2AC11	P0C0S8	2	0	1	0.416	0.234	0	91.30357	4.077578	up_reg	1
RHOV	Q96L33	2	6094	5	0.401	0.233	0	85.68690	3.846255	up_reg	86
CLDN1	O95832	2	15884	6	0.392	0.231	0	84.70039	2.942980	up_reg	1280
H2AC8	P04908	2	12365	8	0.384	0.231	0	91.08903	2.068346	up_reg	1
CXCL10	P02778	2	0	2	0.109	0.230	0	90.08511	6.235378	up_reg	8876
GRN	P28799	2	761	2	0.140	0.230	0	76.98417	2.143488	up_reg	3094
HLA-DPB1	P04440	2	0	4	0.168	0.229	0	87.13757	3.113183	up_reg	1195
SYNGR2	O43760	50	0	1	0.192	0.229	0	81.66832	2.408663	up_reg	14
CDCA4	Q9BXL8	2	2277	2	0.090	0.228	0	63.80400	2.599588	up_reg	44
MATK	P42679	2	3136	3	0.135	0.225	0	83.78212	2.482567	up_reg	1410
MUC5B	Q9HC84	2	1020	3	0.071	0.225	0	65.92865	5.737039	up_reg	1207
CDH1	P12830	2	23050	9	0.076	0.224	0	79.89055	4.933467	up_reg	5706
MPPED2	Q15777	2	0	1	0.120	0.222	0	95.36715	4.417398	up_reg	28
RSPO1	Q2MKA7	37	8	4	0.111	0.221	0	75.36365	3.025055	up_reg	350
TNFAIP2	Q03169	52	0	1	0.238	0.221	0	85.94862	2.993107	up_reg	97
UHRF1	Q96T88	2	16747	6	0.210	0.221	0	81.26714	4.080136	up_reg	696
MUC16	Q8WXI7	2	1521	3	0.085	0.220	0	75.54095	8.476038	up_reg	1352
CD48	P09326	2	761	2	0.445	0.219	0	83.72723	3.054479	up_reg	1312
EPPK1	P58107	2	0	1	0.118	0.219	0	79.61520	6.941326	up_reg	38
PRKCZ	Q05513	2	4419	5	0.054	0.219	0	80.53423	2.469978	up_reg	130
EYA4	O95677	28	0	1	0.371	0.218	0	64.03401	3.012436	up_reg	144
CDC20	Q12834	2	13778	4	0.319	0.217	0	84.85435	6.475074	up_reg	1650
PMAIP1	Q13794	2	3032	2	0.317	0.217	0	82.91014	3.896961	up_reg	738
NRTN	Q99748	2	1521	3	0.352	0.216	0	79.04346	5.712851	up_reg	249
CDH2	P19022	2	2326	5	0.099	0.215	0	79.17653	2.559787	up_reg	1215
NHERF1	O14745	2	1521	3	0.202	0.212	0	72.47472	3.097348	up_reg	466
ITGA4	P13612	2	7750	3	0.145	0.211	0	84.56353	2.107446	up_reg	277
KRT80	Q6KB66	2	0	5	0.411	0.209	0	76.76731	5.731736	up_reg	32
MET	P08581	2	3305	3	0.093	0.209	0	79.58763	2.695561	up_reg	276508
LRP2	P98164	2	761	2	0.160	0.207	0	84.41689	4.927297	up_reg	452
MUC5B	Q9HC84	2	1020	3	0.067	0.207	0	75.11554	5.737039	up_reg	1207
CFAP90	A4QMS7	2	0	1	0.256	0.204	0	75.36202	2.657168	up_reg	0
LSP1	P33241	2	563	2	0.145	0.204	0	60.56910	2.311015	up_reg	316
ARL11	Q969Q4	2	0	1	0.147	0.203	0	88.13514	3.125100	up_reg	38
DNMT3B	Q9UBC3	2	56	2	0.077	0.203	0	73.57543	2.148336	up_reg	2407
SDC1	P18827	2	4415	6	0.400	0.203	0	55.99303	4.335717	up_reg	1549
HOXB4	P17483	2	0	3	0.094	0.202	0	68.07405	4.785876	up_reg	429
MAP7	Q14244	2	0	1	0.366	0.202	0	62.54288	3.092922	up_reg	94
UQCRFS1	P47985	2	0	1	0.381	0.202	0	81.75593	2.088377	up_reg	57
IL1RN	P18510	2	0	1	0.197	0.201	0	87.13193	4.132662	up_reg	3592
TRIB1	Q96RU8	2	0	1	0.268	0.201	0	77.94675	2.875736	up_reg	271
HLA-DQB1	P01920	2	13782	6	0.257	0.200	0	87.11210	4.148044	up_reg	3668
SPINT1	O43278	51	0	1	0.107	0.200	0	77.01837	6.141109	up_reg	238
KRT19	P08727	2	1083	4	0.374	0.199	0	81.40007	3.098124	up_reg	448
PLK4	O00444	2	767	3	0.133	0.199	0	66.92294	2.644551	up_reg	485
LAMA5	O15230	2	3467	4	0.149	0.195	0	79.60429	2.244719	up_reg	154
POLR2F	P61218	2	3038	7	0.081	0.195	0	79.10277	4.942004	up_reg	32
CKS2	P33552	2	0	1	0.368	0.194	0	92.87122	4.440040	up_reg	168
LTB	Q06643	2	1331	3	0.279	0.194	0	78.39808	5.296640	up_reg	2405
PARS2	Q7L3T8	2	0	1	0.407	0.194	0	88.46743	2.174840	up_reg	24
S100A9	P06702	2	2897	5	0.328	0.187	0	94.90595	2.289678	up_reg	2190
SH2B2	O14492	2	0	2	0.200	0.184	0	64.23783	2.606184	up_reg	59
APLP1	P51693	2	0	1	0.120	0.183	0	69.72252	4.237735	up_reg	286
CCL28	Q9NRJ3	2	7221	4	0.193	0.182	0	73.22394	3.991313	up_reg	357
HMGA1	P17096	2	1520	2	0.159	0.181	0	65.46237	6.591907	up_reg	1299
SOX17	Q9H6I2	2	6	2	0.278	0.181	0	59.27884	4.879374	up_reg	1021
ARL4C	P56559	2	0	1	0.393	0.180	0	93.52089	4.733473	up_reg	65
FBN3	Q75N90	12	0	1	0.157	0.180	0	75.79856	5.054065	up_reg	53
PCBD1	P61457	2	0	1	0.378	0.180	0	96.56937	2.014142	up_reg	30
DOK5	Q9P104	2	0	1	0.200	0.179	0	78.36019	5.673957	up_reg	38
CXCL11	O14625	2	1773	3	0.353	0.178	0	77.92419	7.143297	up_reg	1585
CHAC2	Q8WUX2	17	0	1	0.084	0.176	0	93.52453	2.630675	up_reg	16
NDUFA4L2	Q9NRX3	2	9789	8	0.201	0.175	0	84.63933	2.341067	up_reg	53
WWC1	Q8IX03	2	3714	3	0.055	0.175	0	61.50142	5.147188	up_reg	174
LRP8	Q14114	2	1520	2	0.423	0.171	0	73.62178	2.246711	up_reg	139
KSR2	Q6VAB6	2	0	1	0.284	0.169	0	61.41177	5.960690	up_reg	79
C4orf48	Q5BLP8	14	0	1	0.365	0.167	0	78.23739	4.028170	up_reg	3
PCLAF	Q15004	2	0	1	0.264	0.167	0	66.12640	5.401491	up_reg	103
LRP2	P98164	2	761	2	0.183	0.166	0	76.02884	4.927297	up_reg	452
CLEC5A	Q9NY25	2	348	2	0.252	0.165	0	85.45138	2.904175	up_reg	115
DNAH5	Q8TE73	24	0	1	0.245	0.161	0	81.81473	3.828651	up_reg	183
NMU	P48645	2	0	1	0.141	0.161	0	63.72954	8.371797	up_reg	1511
EXOSC4	Q9NPD3	2	0	1	0.335	0.159	0	89.83185	2.636612	up_reg	25
BORA	Q6PGQ7	2	0	1	0.259	0.158	0	50.73243	2.025953	up_reg	4796
LRP2	P98164	2	761	2	0.221	0.158	0	82.10400	4.927297	up_reg	452
NDUFB3	O43676	2	0	1	0.294	0.157	0	86.46141	2.013948	up_reg	28
CCL8	P80075	2	0	2	0.258	0.153	0	89.58629	3.845029	up_reg	703
CLDN7	O95471	2	1242	6	0.254	0.152	0	82.24946	6.596419	up_reg	302
IFIT3	O14879	2	5526	3	0.158	0.152	0	75.74696	2.375046	up_reg	344
GALNT5	Q7Z7M9	2	0	1	0.076	0.151	0	69.18376	3.327325	up_reg	15
MUC16	Q8WXI7	2	1521	3	0.095	0.146	0	75.51818	8.476038	up_reg	1352
PDZK1IP1	Q13113	2	761	2	0.247	0.145	0	65.20753	7.379819	up_reg	81
ESPN	B1AK53	2	3036	5	0.114	0.144	0	68.30997	7.443990	up_reg	202
RGCC	Q9H4X1	2	0	1	0.314	0.141	0	71.58154	2.366748	up_reg	128
COL9A2	Q14055	1	0	3	0.053	0.140	0	55.63427	4.196349	up_reg	167
KLK8	O60259	2	0	1	0.329	0.140	0	88.53643	7.914436	up_reg	184
POMK	Q9H5K3	2	761	2	0.236	0.139	0	91.65736	5.585370	up_reg	24
TNFRSF21	O75509	2	2279	3	0.215	0.137	0	69.40738	2.418514	up_reg	172
CHI3L1	P36222	2	761	3	0.134	0.135	0	94.99146	4.967392	up_reg	1596
COX6B1	P14854	2	13	2	0.393	0.135	0	94.90168	2.489263	up_reg	35
FOXQ1	Q9C009	2	0	1	0.151	0.132	0	62.11694	8.570065	up_reg	207
PITX1	P78337	2	0	1	0.326	0.132	0	63.26645	4.758002	up_reg	479
EPPK1	P58107	2	0	1	0.162	0.131	0	79.60039	6.941326	up_reg	38
RAB25	P57735	41	0	1	0.148	0.130	0	87.08353	7.156164	up_reg	189
CDKN2B	P42772	2	0	1	0.321	0.128	0	90.76140	2.453778	up_reg	2033
CLIC3	O95833	20	0	1	0.143	0.127	0	94.15899	4.900396	up_reg	48
CARD11	Q9BXL7	2	761	2	0.121	0.124	0	72.04895	2.481919	up_reg	557
ESM1	Q9NQ30	2	0	1	0.181	0.124	0	73.14345	3.038808	up_reg	509
MUC5B	Q9HC84	2	1020	3	0.184	0.124	0	56.96292	5.737039	up_reg	1207
TUBB4A	P04350	2	2031	4	0.190	0.124	0	92.24309	3.282229	up_reg	118
ITGB7	P26010	2	2752	2	0.268	0.121	0	82.84386	3.324527	up_reg	73
POU5F1	Q01860	2	14481	8	0.257	0.119	0	66.34535	3.740793	up_reg	3858
TNF	P01375	2	6688	6	0.273	0.119	0	85.00767	6.265458	up_reg	221351
LILRB1	Q8NHL6	2	1319	3	0.177	0.118	0	73.03943	2.334817	up_reg	396
VAV3	Q9UKW4	2	68848	8	0.067	0.117	0	84.41551	4.547079	up_reg	321
LRP2	P98164	2	761	2	0.108	0.115	0	82.21634	4.927297	up_reg	452
FEN1	P39748	2	0	3	0.078	0.113	0	90.03506	2.230667	up_reg	874
TMEM30B	Q3MIR4	9	0	1	0.223	0.113	0	92.35448	3.021734	up_reg	13
MUC5B	Q9HC84	2	1020	3	0.166	0.110	0	54.61585	5.737039	up_reg	1207
KRT16	P08779	2	2509	5	0.333	0.106	0	74.43273	4.141592	up_reg	182
SH3RF2	Q8TEC5	2	0	1	0.059	0.105	0	57.59249	2.729593	up_reg	18
CLU	P10909	2	1521	5	0.158	0.104	0	76.87086	2.491979	up_reg	2364
ESRP2	Q9H6T0	2	0	1	0.052	0.103	0	74.32537	4.950124	up_reg	77
SKA1	Q96BD8	2	3740	3	0.218	0.102	0	85.82242	5.476597	up_reg	114
COX5B	P10606	2	41	3	0.105	0.096	0	85.69271	2.427432	up_reg	136
RIPK4	P57078	2	15	2	0.135	0.096	0	74.60517	6.184659	up_reg	100
ISG15	P05161	2	10014	6	0.503	0.095	0	86.54014	4.583876	up_reg	1808
LYZ	P61626	2	0	1	0.190	0.093	0	94.45464	3.176699	up_reg	688
SFN	P31947	2	73299	6	0.296	0.091	0	93.38504	5.327039	up_reg	2478
HMGA2	P52926	2	761	2	0.202	0.089	0	65.13682	5.165815	up_reg	1858
CARD9	Q9H257	2	0	1	0.125	0.087	0	81.15426	3.240362	up_reg	539
CDCA7	Q9BWT1	2	0	1	0.158	0.087	0	66.71299	3.825804	up_reg	85
FAAP24	Q9BTP7	2	761	2	0.199	0.087	0	90.18733	2.416477	up_reg	35
CHMP4C	Q96CF2	2	0	1	0.263	0.083	0	77.35806	4.735938	up_reg	64
GDF15	Q99988	2	0	1	0.062	0.082	0	75.41460	2.195446	up_reg	2514
LRFN1	Q9P244	2	1520	3	0.146	0.082	0	70.58550	3.127358	up_reg	11
CSF2RA	P15509	2	0	1	0.110	0.079	0	82.07854	2.326266	up_reg	117
E2F2	Q14209	2	0	1	0.180	0.079	0	64.08260	5.446447	up_reg	639
H2AX	P16104	2	8754	10	0.328	0.078	0	87.32992	2.528322	up_reg	7218
ILDR2	Q71H61	2	0	1	0.046	0.075	0	56.53694	2.554303	up_reg	23
CCNB2	O95067	2	21505	5	0.089	0.073	0	80.38333	4.940087	up_reg	453
SPP1	P10451	2	2257	2	0.312	0.072	0	53.13979	5.389308	up_reg	4958
ILDR1	Q86SU0	2	0	1	0.115	0.071	0	58.96387	8.292796	up_reg	49
RYR1	P21817	2	1899	4	0.098	0.071	0	85.54549	3.086482	up_reg	7993
CCNF	P41002	2	0	1	0.276	0.059	0	72.44700	2.582579	up_reg	183
COL10A1	Q03692	1	5	4	-0.010	0.058	0	61.49775	4.041689	up_reg	679
PPP2R2B	Q00005	2	3032	3	0.106	0.055	0	90.41175	3.664496	up_reg	113
LRP2	P98164	2	761	2	0.183	0.052	0	82.08045	4.927297	up_reg	452
SGO1	Q5FBB7	2	0	1	0.108	0.050	0	55.17324	5.338592	up_reg	255
EPPK1	P58107	2	0	1	0.207	0.048	0	78.87880	6.941326	up_reg	38
NKD2	Q969F2	2	0	1	0.151	0.047	0	56.92392	2.149191	up_reg	86
RAP1GAP	P47736	2	2277	2	0.060	0.047	0	70.99696	3.713069	up_reg	184
SKAP1	Q86WV1	2	0	1	0.224	0.046	0	71.43923	5.275064	up_reg	75
COL26A1	Q96A83	1	8	5	0.004	0.044	0	60.65501	3.863487	up_reg	8
TGM1	P22735	2	1487	3	0.097	0.042	0	85.13601	2.974339	up_reg	253
WDR93	Q6P2C0	2	3795	6	0.147	0.041	0	76.99177	2.267609	up_reg	2
LRP2	P98164	2	761	2	0.123	0.038	0	71.99966	4.927297	up_reg	452
COL22A1	Q8NFW1	1	0	3	0.106	0.037	0	54.74523	2.383929	up_reg	58
EPS8L1	Q8TE68	2	0	1	0.064	0.026	0	75.61647	5.101489	up_reg	11
DYRK1B	Q9Y463	25	0	1	0.097	0.022	0	74.53225	2.195558	up_reg	164
HOXB7	P09629	2	761	4	-0.001	0.021	0	66.86952	5.290210	up_reg	318
JUP	P14923	2	14648	4	0.091	0.021	0	81.10563	2.578337	up_reg	484
MUC16	Q8WXI7	2	1521	3	0.186	0.021	0	67.43678	8.476038	up_reg	1352
MAD2L1	Q13257	2	3785	3	0.178	0.019	0	93.75853	3.426759	up_reg	681
C15orf48	Q9C002	2	0	2	0.212	0.018	0	89.84824	5.134800	up_reg	21
SYTL1	Q8IYJ3	2	3037	4	0.036	0.011	0	72.77781	4.342698	up_reg	40
DUSP23	Q9BVJ7	2	0	1	0.465	0.001	0	97.64673	2.213370	up_reg	17

Note: Duplicates removed here

PCSF Druggability Results

external_gene_name	uniprot_gn_id	cluster	betweenness	degree_centrality	pocket	druggability	num_drug_pockets	struct_score	logFC	regulation	citation_score
IL4I1	Q96RQ9	10	0	1	0.511	1.000	1	86.82116	7.731687	up_reg	124
MAPK15	Q8TD08	20	0	1	0.055	1.000	1	69.39014	4.731041	up_reg	63
CACNA1F	O60840	2	1139	3	0.170	0.999	5	67.32468	3.652392	up_reg	184
AQP9	O43315	2	0	1	0.470	0.998	1	91.06600	3.553111	up_reg	637
SULT1C2	O00338	53	0	1	0.298	0.998	1	95.75467	4.617490	up_reg	56
CENPE	Q02224	2	1501	4	0.135	0.997	5	72.55249	2.847355	up_reg	436
RYR1	P21817	2	1899	4	0.226	0.997	3	75.55434	3.086482	up_reg	7993
BNIPL	Q7Z465	2	0	1	0.190	0.996	1	68.65183	3.984513	up_reg	17
SULT2B1	O00204	53	0	1	0.599	0.996	1	87.72190	4.651085	up_reg	124
FAAH2	Q6GMR7	23	0	1	0.082	0.995	1	94.18245	3.735525	up_reg	24
CD9	P21926	2	1521	3	0.063	0.994	1	88.11915	3.619361	up_reg	2704
CENPU	Q71F23	2	0	3	0.002	0.994	1	65.51860	3.558826	up_reg	59
KCNK12	Q9HB15	36	0	1	0.139	0.994	1	73.78490	2.598125	up_reg	25
MELK	Q14680	2	0	1	0.159	0.993	1	70.64372	5.528457	up_reg	659
NOX4	Q9NPH5	2	322	2	0.046	0.993	3	86.75705	2.565399	up_reg	3755
PLPP4	Q5VZY2	45	0	1	0.383	0.993	2	92.00338	5.658002	up_reg	11
XDH	P47989	46	0	1	0.138	0.993	3	96.09594	7.452060	up_reg	800
IDO1	P14902	34	0	1	0.277	0.991	1	93.39839	5.743478	up_reg	2039
KIF11	P52732	2	1046	9	0.141	0.991	1	74.76864	4.407716	up_reg	820
KLC3	Q6P597	11	3	3	0.212	0.991	1	76.01520	4.822387	up_reg	19
CYP2J2	P51589	22	0	1	0.080	0.987	1	93.78906	4.606358	up_reg	707
NINJ2	Q9NZG7	2	0	1	0.185	0.987	3	67.54372	3.668185	up_reg	59
TEAD4	Q15561	2	1521	3	0.243	0.986	2	76.58312	2.660133	up_reg	381
UNC93B1	Q9H1C4	54	0	1	0.082	0.986	1	80.17879	3.392612	up_reg	175
LY86	O95711	15	0	1	0.075	0.983	1	87.70983	3.088945	up_reg	119
TNFAIP8L2	Q6P589	2	761	2	0.017	0.981	1	90.74994	2.015314	up_reg	130
SYK	P43405	2	13379	10	0.203	0.979	2	84.33036	4.407191	up_reg	5393
FBN2	P35556	12	7	3	0.107	0.975	1	75.78393	2.521524	up_reg	313
CACNA1B	Q00975	2	6	2	0.130	0.971	2	60.38413	4.783153	up_reg	334
HAS2	Q92819	2	0	1	0.103	0.970	1	90.70737	2.317929	up_reg	1108
SLC35F2	Q8IXU6	2	0	1	-0.002	0.970	2	82.73241	2.149731	up_reg	26
LGR6	Q9HBX8	37	0	2	0.408	0.967	2	78.17419	3.761788	up_reg	191
LPAR5	Q9H1C0	2	0	1	0.250	0.967	1	83.69589	3.173233	up_reg	108
ALDH3A1	P30838	5	0	2	0.345	0.966	1	97.89977	3.119278	up_reg	316
SGPP2	Q8IWX5	45	0	1	0.102	0.966	1	84.21180	5.853240	up_reg	40
VDR	P11473	2	0	1	0.284	0.966	1	84.69541	3.683154	up_reg	8882
H2BC4	P62807	2	38282	12	0.291	0.965	1	87.82973	2.638893	up_reg	0
LAPTM5	Q13571	38	0	1	0.239	0.964	2	69.27503	2.290592	up_reg	113
NQO1	P15559	2	761	2	0.254	0.963	1	98.32853	2.893693	up_reg	5539
SLC16A3	O15427	2	1520	2	0.025	0.963	1	83.58743	2.015156	up_reg	195
NAXE	Q8NCW5	2	1521	3	0.423	0.962	1	86.87614	2.208627	up_reg	51
CYP4F3	Q08477	22	0	1	0.156	0.961	2	91.82752	4.018495	up_reg	84
TGFA	P01135	2	3905	5	0.202	0.961	1	66.88685	4.466767	up_reg	481
ADGRG1	Q9Y653	2	0	1	0.294	0.960	2	78.01376	4.084734	up_reg	168
DNAH3	Q8TD57	24	0	1	0.164	0.960	4	85.66639	3.642484	up_reg	16
STC2	O76061	2	0	2	0.270	0.960	2	73.29585	3.187642	up_reg	353
FBN3	Q75N90	12	0	1	0.195	0.958	2	75.30388	5.054065	up_reg	53
CYBA	P13498	2	0	2	0.480	0.957	1	77.02989	3.871486	up_reg	1043
TTK	P33981	2	3035	3	0.087	0.956	1	63.95435	5.915254	up_reg	2047
PLK1	P53350	2	53880	14	0.175	0.953	2	85.16989	3.894749	up_reg	2971
CYBB	P04839	2	1700	2	0.295	0.952	3	90.39584	2.576950	up_reg	2670
ERBB4	Q15303	2	3810	3	0.069	0.951	1	73.09162	5.365254	up_reg	2501
TSPAN33	Q86UF1	2	0	1	0.034	0.951	2	89.66649	2.598895	up_reg	32
DSP	P15924	2	2832	2	0.154	0.950	1	78.56539	4.716943	up_reg	5445
IL32	P24001	2	0	1	0.099	0.950	2	71.19002	3.002851	up_reg	626
ASPM	Q8IZT6	2	8922	4	0.434	0.949	4	62.64048	4.312243	up_reg	510
NDUFB9	Q9Y6M9	2	4536	2	-0.051	0.948	1	96.13232	2.289772	up_reg	33
AIFM1	O95831	2	39	2	0.136	0.947	1	85.79458	2.212459	up_reg	647
TDO2	P48775	34	0	1	0.175	0.947	1	90.52437	5.860687	up_reg	223
LAMA5	O15230	2	3467	4	0.086	0.946	2	79.24314	2.244719	up_reg	154
GPR37	O15354	2	0	1	0.097	0.945	5	61.81102	4.508915	up_reg	144
RTN2	O75298	49	0	1	0.162	0.944	2	51.12613	2.365362	up_reg	37
GJB2	P29033	2	1520	2	0.236	0.943	2	86.38640	5.456850	up_reg	2564
PTGS1	P23219	2	0	2	0.142	0.943	1	94.11557	5.423793	up_reg	3039
IFI27	P40305	2	0	1	0.066	0.942	1	52.14211	4.811702	up_reg	273
MYO3B	Q8WXR4	2	0	2	0.144	0.942	1	75.66990	6.420588	up_reg	22
TNFRSF12A	Q9NP84	2	1609	4	0.111	0.942	1	73.27291	3.640033	up_reg	446
TRPV6	Q9H1D0	2	0	1	0.341	0.941	3	80.74593	3.389083	up_reg	747
H2BC9	Q93079	2	24695	11	0.364	0.940	2	88.14311	4.450921	up_reg	3
RORC	P51449	2	0	1	0.252	0.940	1	75.84376	4.448796	up_reg	1288
TNFSF10	P50591	2	761	2	0.184	0.940	1	82.39667	2.187216	up_reg	3737
P2RY2	P41231	43	0	1	0.120	0.939	1	79.19662	4.039141	up_reg	470
RAC2	P15153	2	1171	7	0.227	0.939	1	93.54571	2.156389	up_reg	917
RIMKLA	Q8IXN7	2	0	1	0.297	0.938	1	81.13650	3.884952	up_reg	4
H2BC12	O60814	2	24896	11	0.241	0.937	1	88.05779	3.203629	up_reg	2
MPZL2	O60487	40	0	1	0.433	0.937	2	89.47771	3.309876	up_reg	35
RAC3	P60763	2	18877	11	0.341	0.937	1	93.83371	2.514936	up_reg	299
DNAH5	Q8TE73	24	0	1	0.234	0.936	1	81.69210	3.828651	up_reg	183
IL2RA	P01589	2	0	1	0.000	0.936	1	72.50829	2.966958	up_reg	1993
RSAD2	Q8WXG1	2	380	2	0.193	0.935	1	87.95684	2.536852	up_reg	393
PPP4C	P60510	2	1521	3	0.387	0.933	1	94.87746	2.136177	up_reg	32
IFIT1	P09914	2	0	1	0.057	0.930	1	94.17439	2.860614	up_reg	577
MUC5B	Q9HC84	2	1020	3	0.112	0.930	1	82.35068	5.737039	up_reg	1207
APOA1	P02647	2	9356	8	0.278	0.929	3	73.61168	3.065972	up_reg	3491
CDC45	O75419	2	884	2	0.323	0.926	1	92.88743	4.831525	up_reg	594
CDC6	Q99741	2	761	3	0.244	0.922	2	69.83948	3.142206	up_reg	1059
CHST6	Q9GZX3	18	0	1	0.409	0.920	1	90.80083	5.468416	up_reg	84
NR2F6	P10588	2	0	1	0.399	0.917	1	79.75002	3.297460	up_reg	89
SDC4	P31431	2	4689	3	0.270	0.917	2	63.14462	2.128542	up_reg	556
LGALS9	O00182	2	0	1	0.247	0.914	3	85.12848	2.655331	up_reg	533
EPPK1	P58107	2	0	1	0.247	0.908	1	77.46931	6.941326	up_reg	38
CENPF	P49454	2	10672	3	0.122	0.906	1	71.41875	4.302935	up_reg	385
ATP10B	O94823	9	0	1	0.117	0.904	2	71.43291	5.180540	up_reg	18
HCST	Q9UBK5	2	1076	3	0.330	0.904	2	67.31898	2.736939	up_reg	246
ASS1	P00966	2	0	1	0.103	0.902	1	95.63537	3.299729	up_reg	402
AGR2	O95994	2	5272	5	0.263	0.901	1	87.41946	5.133482	up_reg	449
CDCP1	Q9H5V8	2	0	1	0.276	0.901	1	78.35387	5.466835	up_reg	234
PBK	Q96KB5	2	0	2	0.152	0.901	1	84.90700	5.819542	up_reg	782
MGST1	P10620	39	0	1	0.541	0.900	1	79.02661	3.365294	up_reg	238
ATP5MC1	P05496	2	3791	3	0.401	0.898	1	72.69576	2.063501	up_reg	4
TOP2A	P11388	2	22036	7	0.045	0.897	1	76.40832	5.212828	up_reg	1327
ITGB8	P26012	2	0	1	0.085	0.896	1	76.46707	2.820420	up_reg	131
ATP5MF	P56134	2	0	1	0.423	0.892	3	74.16835	2.318005	up_reg	2
CTSC	P53634	2	0	3	0.338	0.892	2	90.37857	2.162863	up_reg	316
PTX3	P26022	2	135	2	0.266	0.891	2	79.75132	2.728436	up_reg	2010
GJB1	P08034	2	0	1	0.333	0.890	1	80.05050	7.474133	up_reg	358
ZNF492	Q9P255	56	0	1	0.218	0.888	1	73.55861	2.697025	up_reg	6
KLHL14	Q9P2G3	6	0	1	0.483	0.887	1	88.14009	5.754363	up_reg	22
LRP2	P98164	2	761	2	0.255	0.887	1	81.80994	4.927297	up_reg	452
ANPEP	P15144	2	761	2	0.232	0.886	1	93.75126	3.535249	up_reg	188
HMMR	O75330	2	0	1	0.192	0.886	2	76.10490	5.098101	up_reg	249
ESPL1	Q14674	2	0	1	0.619	0.885	1	75.77835	4.967101	up_reg	146
KIF9	Q9HAQ2	2	7104	13	0.202	0.885	1	75.21325	2.195679	up_reg	31
CD3E	P07766	2	14667	11	0.191	0.884	1	73.51280	2.881956	up_reg	540
BIK	Q13323	2	761	2	0.409	0.883	2	62.54290	6.029953	up_reg	1275
TUBA1C	Q9BQE3	2	861	2	0.219	0.883	1	91.65244	3.360826	up_reg	52
CIT	O14578	2	4278	2	0.129	0.882	1	70.15278	3.109393	up_reg	8634
PKP3	Q9Y446	2	31976	3	0.070	0.881	1	69.28451	7.141531	up_reg	91
TJP3	O95049	2	0	4	0.067	0.880	2	66.58409	6.724088	up_reg	60
LRRC43	Q8N309	2	0	1	0.240	0.879	1	74.70035	2.069984	up_reg	0
GRIK3	Q13003	2	17866	8	0.152	0.878	1	82.38048	3.473939	up_reg	66
BAIAP2L1	Q9UHR4	2	3579	4	0.324	0.876	2	74.93578	4.062937	up_reg	46
TSPAN15	O95858	2	2277	2	0.296	0.875	2	87.94298	3.591096	up_reg	34
HLA-DOA	P06340	2	7	4	0.429	0.874	1	90.25303	3.324934	up_reg	61
FUT2	Q10981	32	0	1	0.311	0.872	2	90.42101	2.453333	up_reg	560
H2BC11	P06899	2	72	9	0.250	0.870	2	85.69804	3.968938	up_reg	1
KREMEN2	Q8NCW0	37	0	1	0.459	0.870	1	76.82793	7.640887	up_reg	36
KIF15	Q9NS87	2	2175	7	0.241	0.869	1	72.02130	3.950703	up_reg	155
PYCR1	P32322	47	0	1	0.336	0.869	2	90.06781	2.897004	up_reg	158
IL23A	Q9NPF7	2	0	1	0.205	0.868	2	80.95746	2.267386	up_reg	706
DIAPH3	Q9NSV4	2	322	2	0.164	0.866	2	71.81813	4.609425	up_reg	86
LAPTM4B	Q86VI4	38	0	1	0.211	0.865	1	61.67725	3.214999	up_reg	179
SLC5A1	P13866	2	0	1	0.444	0.865	1	84.10975	6.574268	up_reg	812
SVOPL	Q8N434	49	0	1	0.061	0.862	1	84.05384	3.101728	up_reg	14
CXADR	P78310	2	0	1	0.405	0.860	1	79.48562	5.200874	up_reg	83
MARVELD3	Q96A59	2	0	3	0.108	0.860	1	65.32157	3.677035	up_reg	36
NRCAM	Q92823	2	1726	4	0.090	0.859	2	78.95628	2.470745	up_reg	323
HTR3A	P46098	2	0	1	0.422	0.858	2	83.46451	10.598163	up_reg	265
PROM1	O43490	2	335	2	0.171	0.857	2	85.89768	5.868539	up_reg	2840
SLC7A7	Q9UM01	2	0	1	0.011	0.853	1	83.51919	2.184124	up_reg	198
ARFGEF3	Q5TH69	2	0	1	0.051	0.852	3	65.48151	3.121775	up_reg	16
CACNA1A	O00555	2	4536	3	0.201	0.851	2	57.97536	2.232175	up_reg	1045
CXXC5	Q7LFL8	2	0	1	0.110	0.849	1	60.75966	4.423334	up_reg	99
BUB1B	O60566	2	3360	6	0.211	0.846	2	64.72058	4.320179	up_reg	471
GRIN2D	O15399	2	0	2	0.143	0.846	3	64.00209	3.116091	up_reg	93
USP43	Q70EL4	2	470	2	0.025	0.846	2	61.36801	3.739775	up_reg	14
LAMB3	Q13751	2	0	1	0.212	0.844	2	78.10768	4.685454	up_reg	288
POSTN	Q15063	2	0	1	0.152	0.839	2	80.24478	2.937741	up_reg	1643
SLC2A1	P11166	2	2279	3	0.190	0.839	1	89.61531	3.442262	up_reg	3562
CCNO	P22674	2	761	3	0.405	0.838	2	79.73102	2.663074	up_reg	142
IL27RA	Q6UWB1	2	761	2	0.336	0.833	1	79.02110	2.953478	up_reg	214
TYMP	P19971	46	0	1	0.402	0.833	2	93.01893	2.648306	up_reg	270
CX3CR1	P49238	2	1960	6	0.114	0.832	2	80.21817	4.725471	up_reg	3143
WNT7B	P56706	2	0	1	0.461	0.832	2	89.56172	7.353727	up_reg	427
MRPL47	Q9HD33	2	1164	3	0.233	0.830	1	84.37084	2.125313	up_reg	12
TMC6	Q7Z403	2	761	2	0.125	0.830	6	72.55287	2.977559	up_reg	76
IRF6	O14896	2	90	2	0.289	0.829	1	74.17857	3.540215	up_reg	507
FSBP	O95073	2	0	1	0.297	0.828	1	70.03120	2.914093	up_reg	58
RET	P07949	2	3789	4	0.127	0.827	1	79.44206	2.801801	up_reg	11194
GJB3	O75712	2	761	2	0.462	0.826	4	79.18052	6.360123	up_reg	328
KCNJ12	Q14500	2	0	1	0.160	0.823	2	81.21053	2.050148	up_reg	50
LAMC2	Q13753	2	0	1	0.153	0.822	1	74.86195	4.997825	up_reg	472
FAM3B	P58499	30	0	1	0.319	0.821	2	93.09627	6.055449	up_reg	64
UPK3B	Q9BT76	2	0	1	0.394	0.821	1	52.89733	4.391774	up_reg	21
BCL2L1	Q07817	2	2177	5	0.269	0.820	1	73.63605	2.256294	up_reg	8522
ADGRE2	Q9UHX3	2	0	1	0.306	0.819	2	79.23141	2.147655	up_reg	49
NDUFB11	Q9NX14	2	0	1	0.410	0.818	1	78.63169	2.037892	up_reg	35
RASAL1	O95294	2	0	1	0.120	0.818	3	88.58747	6.257054	up_reg	78
CYC1	P08574	2	0	1	0.109	0.817	1	86.38440	2.331383	up_reg	883
CENPA	P49450	2	17610	6	0.140	0.815	2	82.07836	6.059723	up_reg	1089
BMP7	P18075	12	7	3	0.232	0.814	2	76.70694	7.157820	up_reg	3269
KIF20A	O95235	2	24557	13	0.333	0.814	3	67.30456	5.657319	up_reg	301
CXCL16	Q9H2A7	2	40	2	0.204	0.808	2	65.97562	3.366446	up_reg	927
TRPV4	Q9HBA0	2	761	2	0.132	0.803	5	72.00033	3.177434	up_reg	2211
SMAD1	Q15797	2	0	1	0.240	0.801	1	81.78024	2.105853	up_reg	3204
ALG3	Q92685	6	0	1	0.084	0.800	1	89.19005	2.839320	up_reg	131
LRRC46	Q96FV0	2	0	1	0.095	0.800	1	64.78600	2.513569	up_reg	7
NOTUM	Q6P988	2	0	1	0.466	0.800	1	84.58992	7.917860	up_reg	341
TPM3	P06753	2	8572	8	0.348	0.799	1	91.78888	2.201758	up_reg	485
TREM2	Q9NZC2	2	0	2	0.411	0.799	1	77.04992	3.818614	up_reg	1706
MUC16	Q8WXI7	2	1521	3	0.180	0.798	1	55.96839	8.476038	up_reg	1352
NRAS	P01111	2	8745	6	0.256	0.798	1	92.29668	2.115169	up_reg	7121
NKG7	Q16617	2	0	1	0.270	0.797	1	86.50265	3.348089	up_reg	82
SLC12A5	Q9H2X9	42	0	1	0.167	0.797	3	78.73929	2.764017	up_reg	143
BRCA2	P51587	2	32217	9	0.083	0.796	1	65.83808	2.245119	up_reg	14293
VANGL1	Q8TAA9	2	4805	6	0.038	0.796	2	75.85692	2.706602	up_reg	163
DAPP1	Q9UN19	2	0	1	0.046	0.794	1	79.27173	3.771736	up_reg	58
B3GNT3	Q9Y2A9	2	3789	3	0.149	0.793	1	88.42372	7.460360	up_reg	42
DSC3	Q14574	2	0	1	0.135	0.793	1	74.81262	2.160385	up_reg	181
RTKN	Q9BST9	2	0	1	0.115	0.793	1	72.73822	2.656687	up_reg	69
SECTM1	Q8WVN6	2	0	1	0.407	0.792	1	75.41749	2.268843	up_reg	26
SCARA3	Q6AZY7	50	0	1	0.222	0.790	4	71.06544	2.625480	up_reg	53
AURKB	Q96GD4	2	7020	6	0.060	0.789	2	79.85404	5.582702	up_reg	1367
PIPOX	Q9P0Z9	2	453	2	0.845	0.789	3	94.41585	3.104421	up_reg	59
FUT1	P19526	32	0	1	0.333	0.788	1	88.46001	2.677239	up_reg	317
KRT86	O43790	2	13	5	0.408	0.788	4	75.55742	5.650357	up_reg	27
ACTR3C	Q9C0K3	2	0	1	0.040	0.786	1	88.11260	2.000050	up_reg	2
MX2	P20592	2	0	1	0.177	0.784	1	78.01712	2.755543	up_reg	1098
TIMELESS	Q9UNS1	2	2280	6	0.482	0.784	2	75.06448	2.414253	up_reg	1146
FCER1G	P30273	2	1521	4	0.480	0.783	1	72.33766	3.253477	up_reg	173
CDC25C	P30307	2	0	1	0.362	0.777	1	64.18249	6.227772	up_reg	1461
RAB27B	O00194	2	0	1	0.070	0.777	1	86.79901	2.886397	up_reg	230
HLA-DPA1	P20036	2	40869	5	0.282	0.776	1	90.64308	3.525234	up_reg	363
PIGR	P01833	35	0	1	0.017	0.776	1	77.21791	3.975115	up_reg	702
CHAC1	Q9BUX1	17	0	1	0.391	0.775	1	86.16639	2.901424	up_reg	155
TNFSF15	O95150	2	0	1	0.272	0.775	2	82.11392	4.283946	up_reg	467
CCR5	P51681	2	119	2	0.253	0.774	1	85.29439	2.420445	up_reg	10827
GZMB	P10144	2	2279	3	0.347	0.774	1	92.52045	4.083414	up_reg	2459
FGF18	O76093	2	620	2	0.380	0.771	2	87.67060	5.957364	up_reg	396
ST14	Q9Y5Y6	51	0	1	0.160	0.771	2	81.25730	7.158208	up_reg	577
WDR62	O43379	2	0	1	0.088	0.770	2	61.36502	3.041289	up_reg	124
PLEKHH1	Q9ULM0	2	0	1	0.175	0.767	2	70.18185	2.350357	up_reg	4
FZD2	Q14332	2	1521	3	0.544	0.766	4	84.43777	2.649653	up_reg	254
LGR5	O75473	37	3	2	0.267	0.766	4	80.74472	3.946516	up_reg	2020
ORC1	Q13415	2	2071	4	0.154	0.765	1	67.97461	2.787799	up_reg	375
ALPL	P05186	2	0	1	0.370	0.761	2	93.75407	4.455983	up_reg	1060
ANLN	Q9NQW6	2	10469	5	0.121	0.760	1	59.87419	3.455958	up_reg	227
PAK6	Q9NQU5	2	0	1	0.452	0.760	4	67.07498	3.389624	up_reg	123
TUBA1B	P68363	2	117	2	0.192	0.760	2	92.25708	2.287882	up_reg	57
LYN	P07948	2	49848	19	0.072	0.759	1	83.72670	2.498330	up_reg	3594
SLC7A11	Q9UPY5	2	761	2	0.376	0.758	3	86.60983	2.106353	up_reg	1518
THY1	P04216	2	761	2	0.334	0.756	1	83.05667	3.086846	up_reg	6210
LMNB1	P20700	2	325	2	0.275	0.754	2	82.63466	3.288592	up_reg	199
NDUFB7	P17568	2	0	1	0.266	0.753	1	88.93270	2.055041	up_reg	31
CCR1	P32246	2	719	3	0.143	0.752	1	83.11436	2.538960	up_reg	1807
MSR1	P21757	2	2506	6	0.363	0.749	1	71.98684	2.514585	up_reg	611
EYA2	O00167	28	2	2	0.223	0.748	1	69.03617	6.536633	up_reg	130
CD180	Q99467	15	0	1	0.355	0.747	1	93.23928	3.301753	up_reg	151
CENPL	Q8N0S6	2	4202	4	0.229	0.746	2	83.65047	2.321809	up_reg	22
AMN	Q9BXJ7	2	0	1	0.320	0.745	1	80.93990	5.031542	up_reg	1960
CBLC	Q9ULV8	2	102	2	0.215	0.744	1	81.16177	8.008650	up_reg	381
TXK	P42681	2	1520	2	0.210	0.743	1	80.40473	2.723460	up_reg	90
ACOT4	Q8N9L9	3	0	1	0.140	0.740	1	96.46060	2.828725	up_reg	23
RGS19	P49795	2	0	1	0.119	0.740	2	79.47628	3.524701	up_reg	63
ASB9	Q96DX5	8	1	2	0.225	0.738	1	92.22385	2.355072	up_reg	31
UNC5A	Q6ZN44	2	0	1	0.108	0.737	1	78.25560	5.877999	up_reg	71
SPTBN2	O15020	2	4273	4	0.242	0.736	3	76.77521	4.481006	up_reg	98
CD109	Q6YHK3	2	761	2	0.287	0.734	2	81.37547	2.781852	up_reg	265
FUT3	P21217	30	0	1	0.263	0.734	2	90.59422	4.921716	up_reg	215
ALDH3B2	P48448	5	0	2	0.218	0.732	2	94.98486	8.969782	up_reg	26
BTC	P35070	2	2783	3	0.290	0.731	1	72.38943	2.703718	up_reg	3190
NDUFA3	O95167	2	0	1	0.274	0.730	1	96.84498	2.073884	up_reg	15
CFAP45	Q9UL16	2	1552	5	0.131	0.728	3	74.80989	2.226990	up_reg	15
BCAM	P50895	2	0	1	0.182	0.725	3	84.58449	4.415965	up_reg	425
CNIH2	Q6PI25	2	19080	5	0.314	0.723	2	87.25387	2.690596	up_reg	37
KRT8	P05787	2	4632	6	0.432	0.721	1	76.32674	6.489903	up_reg	425
OSM	P13725	2	1111	2	0.107	0.721	1	79.62908	2.173526	up_reg	3150
MMP9	P14780	2	4920	4	0.191	0.717	2	82.25628	5.237949	up_reg	34223
POLQ	O75417	2	0	2	0.104	0.717	1	59.48627	3.988411	up_reg	184
MGST2	Q99735	39	0	1	0.330	0.715	1	93.94066	2.026180	up_reg	69
ATP6V0E2	Q8NHE4	2	1521	3	0.416	0.712	1	94.37485	2.427263	up_reg	8
CACNG4	Q9UBN1	2	5285	2	0.125	0.712	1	65.72441	6.967106	up_reg	36
KPNA2	P52292	2	2308	5	0.024	0.711	1	86.10732	3.953899	up_reg	312
SHCBP1	Q8NEM2	2	0	1	0.180	0.711	1	73.69646	2.980451	up_reg	65
GPR19	Q15760	27	0	1	0.271	0.708	2	74.77012	5.197318	up_reg	30
SPC25	Q9HBM1	2	0	1	0.390	0.708	1	90.25548	4.349788	up_reg	106
FAM166B	A8MTA8	2	0	6	0.110	0.707	1	69.27333	3.014622	up_reg	4
FANCA	O15360	2	2277	2	0.135	0.707	1	74.56587	2.596562	up_reg	687
CMPK2	Q5EBM0	21	0	1	0.064	0.706	2	87.31019	3.113808	up_reg	67
PERP	Q96FX8	2	31898	6	0.129	0.705	1	82.35155	3.211249	up_reg	673
FOXM1	Q08050	2	1527	4	0.173	0.701	1	51.07629	5.310591	up_reg	2251
CRB3	Q9BUF7	2	0	1	0.297	0.700	1	70.34841	6.178867	up_reg	484
CCNB1	P14635	2	76783	14	0.078	0.699	1	77.77241	3.784353	up_reg	2285
CD6	P30203	2	0	1	0.079	0.699	1	66.69789	2.141497	up_reg	697
CD7	P09564	2	1521	3	0.383	0.699	2	77.62312	2.751900	up_reg	2691
FYB1	O15117	2	0	1	0.418	0.698	1	58.39229	2.503950	up_reg	86
EGLN3	Q9H6Z9	2	0	1	0.068	0.697	3	91.56092	3.193540	up_reg	295
NCAPD2	Q15021	2	0	3	0.115	0.697	1	79.98735	2.560562	up_reg	36
PLPP2	O43688	45	1	2	0.205	0.694	1	85.85271	3.843634	up_reg	14
STIL	Q15468	2	0	1	0.163	0.693	1	53.64950	3.519855	up_reg	469
CD8A	P01732	2	558	3	0.263	0.692	1	79.23665	2.123590	up_reg	573
IL1RAP	Q9NPH3	2	0	1	0.211	0.692	1	86.22484	3.030829	up_reg	257
LDHA	P00338	2	0	2	0.089	0.690	1	96.06050	2.195336	up_reg	2225
TNFRSF11B	O00300	2	0	1	0.349	0.688	1	87.00873	4.469606	up_reg	2628
CSPG5	O95196	2	0	1	0.081	0.686	1	52.88670	4.429149	up_reg	42
GRIN2A	Q12879	2	4542	3	0.064	0.686	1	60.41927	3.737127	up_reg	429
NCAPH	Q15003	2	0	3	0.198	0.683	1	60.71979	5.188544	up_reg	71
RAB6B	Q9NRW1	2	0	1	0.239	0.683	1	86.02474	2.332450	up_reg	35
SKA3	Q8IX90	2	4414	4	0.354	0.683	1	64.75869	5.662079	up_reg	97
ATP2B2	Q01814	2	0	1	0.151	0.681	2	73.94863	4.507063	up_reg	155
KCP	Q6ZWJ8	12	0	1	0.112	0.681	2	72.93541	4.945915	up_reg	315
PIK3CG	P48736	2	9360	4	0.145	0.681	2	88.42052	2.098934	up_reg	562
CCDC6	Q16204	2	0	1	0.565	0.678	2	76.03680	2.126289	up_reg	199
USP18	Q9UMW8	2	0	1	0.065	0.678	1	84.05593	3.392279	up_reg	351
TRIP13	Q15645	2	1521	3	0.249	0.677	2	86.97940	3.848280	up_reg	197
HAVCR2	Q8TDQ0	2	1520	2	0.115	0.676	2	71.85756	2.594164	up_reg	1252
BCAT1	P54687	10	0	1	0.358	0.674	1	95.00595	2.614531	up_reg	265
PKMYT1	Q99640	2	16270	3	0.142	0.674	1	75.59028	5.618007	up_reg	107
WNT10A	Q9GZT5	2	0	1	0.100	0.672	1	80.83386	7.182905	up_reg	400
SELL	P14151	2	714	2	0.321	0.670	1	85.32516	2.655413	up_reg	6836
DLGAP5	Q15398	2	4794	4	0.128	0.669	1	56.37102	5.302585	up_reg	180
RAD54L	Q92698	2	0	1	0.171	0.669	1	80.51223	4.209123	up_reg	180
APBB1IP	Q7Z5R6	2	5286	3	0.280	0.668	1	73.44023	2.145425	up_reg	56
HDAC9	Q9UKV0	2	8	6	0.104	0.668	2	64.41926	2.313913	up_reg	455
KIF4A	O95239	2	1470	2	0.244	0.668	3	72.17122	5.153087	up_reg	226
MRPS12	O15235	2	1743	3	0.312	0.667	1	87.35241	2.446360	up_reg	14
TMEM102	Q8N9M5	48	0	1	0.236	0.666	1	74.64646	3.553872	up_reg	5
CAPG	P40121	2	0	1	0.313	0.665	1	86.70529	3.387519	up_reg	249
FOLR1	P15328	2	608	4	0.090	0.662	1	91.11366	9.610444	up_reg	357
RAB3D	O95716	48	0	1	0.185	0.662	2	85.15368	2.740453	up_reg	166
COX5A	P20674	2	14138	6	0.376	0.660	1	88.10962	2.578447	up_reg	134
TREM1	Q9NP99	2	0	1	0.034	0.660	1	71.42913	3.025812	up_reg	1118
TUBB4B	P68371	2	4864	8	0.258	0.659	2	92.02804	2.059976	up_reg	44
XRCC2	O43543	2	761	5	0.516	0.659	1	87.09828	3.236290	up_reg	430
MCM4	P33991	2	9512	9	0.217	0.658	3	73.74330	2.743419	up_reg	448
NEK2	P51955	2	7688	2	0.136	0.658	2	78.74819	6.921414	up_reg	489
TLR7	Q9NYK1	54	0	1	0.198	0.657	4	87.54334	3.806294	up_reg	4757
TPX2	Q9ULW0	2	761	2	0.402	0.656	1	64.23851	6.263362	up_reg	684
CHST4	Q8NCG5	18	0	1	0.363	0.655	2	90.77228	5.171505	up_reg	34
NCAPG	Q9BPX3	2	0	3	0.163	0.655	1	82.50230	4.802859	up_reg	252
BAK1	Q16611	2	2279	3	0.535	0.654	2	81.54397	2.273926	up_reg	1896
SHISA9	B4DS77	2	0	1	0.277	0.654	1	56.95488	5.720736	up_reg	18
HLA-DRA	P01903	2	0	4	0.277	0.653	1	89.58587	3.994244	up_reg	1221
MYB	P10242	2	0	1	0.162	0.652	1	59.19859	5.712612	up_reg	9106
RNF43	Q68DV7	37	0	3	0.124	0.651	1	54.60221	2.425714	up_reg	369
ROMO1	P60602	2	636	2	0.413	0.649	3	78.13109	2.159277	up_reg	115
TMEM63C	Q9P1W3	2	0	1	0.125	0.649	1	74.57350	3.490019	up_reg	12
DLGAP3	O95886	2	0	1	0.282	0.648	1	50.70109	3.775359	up_reg	25
PARD6B	Q9BYG5	2	3192	2	0.345	0.647	1	71.24402	3.304514	up_reg	40
COL13A1	Q5TAT6	1	0	2	0.197	0.646	1	57.97463	2.870544	up_reg	75
AQP5	P55064	2	761	2	0.392	0.643	1	93.50506	7.968789	up_reg	1158
FOLH1	Q04609	2	2288	4	0.322	0.643	1	94.01397	2.144560	up_reg	1490
PCNA	P12004	2	4677	7	0.569	0.642	1	94.33015	2.104983	up_reg	25415
CDR2L	Q86X02	2	0	1	0.434	0.641	2	74.20117	3.691110	up_reg	26
DMTN	Q08495	2	0	1	0.221	0.641	1	64.63463	3.098244	up_reg	60
IGF2BP2	Q9Y6M1	2	761	2	0.107	0.640	1	77.75247	2.401479	up_reg	650
RAD51	Q06609	2	4984	5	0.282	0.640	1	91.59067	3.625870	up_reg	5831
ADD2	P35612	2	761	2	0.203	0.639	4	66.27120	3.978666	up_reg	80
CLDN10	P78369	2	8628	9	0.400	0.636	1	79.69633	6.283497	up_reg	99
GINS4	Q9BRT9	2	0	2	0.324	0.635	1	90.74832	2.575322	up_reg	36
GPRIN2	O60269	2	0	1	0.172	0.634	1	50.28259	4.769083	up_reg	23
TEC	P42680	2	2277	4	0.096	0.634	1	85.88542	2.329341	up_reg	6593
CD2	P06729	2	97	4	0.375	0.633	2	78.29759	3.177594	up_reg	18110
MYBL2	P10244	2	0	1	0.066	0.633	1	58.45051	6.939571	up_reg	478
CD24	P25063	2	0	1	0.228	0.632	1	63.89011	8.713693	up_reg	4011
CDK2AP1	O14519	16	0	1	0.451	0.632	1	76.36776	3.230913	up_reg	92
KCNN4	O15554	2	761	2	0.429	0.632	1	84.85052	3.886967	up_reg	641
SLC44A4	Q53GD3	2	0	1	0.128	0.632	1	83.76549	4.642249	up_reg	56
CLDN3	O15551	2	669	5	0.271	0.631	1	81.42759	10.441852	up_reg	485
KRT6A	P02538	2	969	5	0.307	0.631	1	69.50787	3.041425	up_reg	196
L1CAM	P32004	2	5550	4	0.068	0.631	1	79.35279	3.823699	up_reg	2439
NETO2	Q8NC67	42	0	1	0.302	0.631	1	72.42280	2.079967	up_reg	77
SYNE4	Q8N205	11	0	1	0.168	0.628	1	57.78246	4.109102	up_reg	9
CCL4	P13236	2	2410	3	0.270	0.626	1	88.97642	3.213667	up_reg	14603
KRT17	Q04695	2	81	3	0.276	0.626	1	79.60908	6.228925	up_reg	271
PLAU	P00749	2	998	3	0.414	0.626	1	82.30347	3.727477	up_reg	569
RIBC2	Q9H4K1	2	2064	7	0.365	0.625	1	86.74874	3.939408	up_reg	11
RMI2	Q96E14	2	2582	7	0.286	0.624	1	89.81185	2.702399	up_reg	75
H3C10	P68431	2	0	3	0.351	0.623	1	87.28692	2.688200	up_reg	0
H3C8	P68431	2	11	3	0.351	0.623	1	87.28692	7.878421	up_reg	0
PCP4	P48539	44	0	1	0.348	0.623	1	77.79623	3.572944	up_reg	144
NUF2	Q9BZD4	2	0	1	0.317	0.622	2	89.42833	4.636580	up_reg	201
ACKR2	O00590	2	3092	3	0.220	0.621	2	80.01695	4.237197	up_reg	100
ALK	Q9UM73	2	761	2	0.087	0.620	3	67.27647	4.194048	up_reg	14702
CABP4	P57796	2	0	1	0.276	0.620	1	66.10069	2.568051	up_reg	49
C1QC	P02747	2	940	2	0.290	0.619	1	81.16742	2.927810	up_reg	159
MAL2	Q969L2	2	0	1	0.336	0.619	1	84.15024	8.534437	up_reg	176
BLM	P54132	2	1899	5	0.161	0.616	1	60.95775	3.668059	up_reg	5420
CCND1	P24385	2	30015	9	0.313	0.616	2	88.55158	3.545879	up_reg	6387
DCTPP1	Q9H773	21	0	1	0.339	0.616	1	85.40514	2.697626	up_reg	24
SLC34A2	O95436	2	0	1	0.040	0.616	3	72.96990	7.493592	up_reg	287
CKAP2	Q8WWK9	19	0	1	0.332	0.615	2	59.53707	2.952651	up_reg	74
CENPN	Q96H22	2	0	2	0.300	0.612	1	86.20997	2.369029	up_reg	68
SLPI	P03973	2	0	1	0.442	0.612	1	84.39588	7.842239	up_reg	928
IL2RG	P31785	2	2925	4	0.234	0.609	1	76.81580	2.149183	up_reg	1136
MPP7	Q5T2T1	2	322	2	0.114	0.606	1	81.02127	2.488989	up_reg	39
CD74	P04233	2	3917	5	0.198	0.605	1	70.67138	3.873722	up_reg	1184
CD96	P40200	2	0	1	0.113	0.605	1	66.54424	2.031664	up_reg	234
ESRP1	Q6NXG1	2	0	1	0.187	0.604	1	78.06816	8.042375	up_reg	197
IQGAP3	Q86VI3	2	0	1	0.181	0.604	2	79.62675	5.163314	up_reg	85
CDK2AP2	O75956	16	0	1	0.476	0.603	1	75.74548	2.120070	up_reg	40
HOOK1	Q9UJC3	2	0	1	0.269	0.603	3	82.67534	3.529558	up_reg	73
VAV1	P15498	2	853	3	0.182	0.602	2	87.14542	2.680345	up_reg	1025
CCL4L2	Q8NHW4	2	0	1	0.140	0.601	1	90.27970	2.125786	up_reg	18
DSC2	Q02487	2	3552	2	0.275	0.600	1	76.56279	5.332860	up_reg	297
PYCR3	Q53H96	47	0	1	0.416	0.600	1	94.81272	2.239585	up_reg	9
CENPK	Q9BS16	2	0	3	0.253	0.599	1	81.70731	3.365918	up_reg	50
HOMER2	Q9NSB8	2	1521	3	0.431	0.599	2	89.11372	3.173158	up_reg	101
C1QA	P02745	2	1659	2	0.216	0.597	1	82.87227	2.309558	up_reg	313
RCOR2	Q8IZ40	2	0	1	0.110	0.597	1	68.12330	3.046027	up_reg	65
UNC5B	Q8IZJ1	2	6797	4	0.216	0.597	1	77.98145	2.185793	up_reg	231
APOBEC3B	Q9UH17	2	0	1	0.283	0.593	1	88.33103	4.139712	up_reg	399
B3GNT2	Q9NY97	2	0	1	0.183	0.592	1	91.28206	2.353972	up_reg	44
KCNJ11	Q14654	2	0	1	0.126	0.592	1	84.56523	2.949554	up_reg	1019
CXCR3	P49682	2	1658	3	0.210	0.590	1	80.64541	4.557329	up_reg	4275
IFI44L	Q53G44	2	1520	3	0.257	0.590	1	86.36570	2.148762	up_reg	185
CASP8	Q14790	2	5020	5	0.223	0.589	2	81.49031	2.275285	up_reg	5488
OAS2	P29728	19	2	3	0.270	0.588	1	87.74127	4.206419	up_reg	278
UBASH3B	Q8TF42	2	0	1	0.138	0.588	2	85.36864	2.937062	up_reg	54
CXCR4	P61073	2	10567	8	0.122	0.585	1	82.80839	3.415298	up_reg	15921
BCL11A	Q9H165	2	0	1	0.176	0.584	3	52.46475	5.681517	up_reg	706
NRARP	Q7Z6K4	2	1520	2	0.142	0.584	1	82.92880	3.105494	up_reg	46
RACGAP1	Q9H0H5	2	1421	5	0.133	0.584	2	69.86318	3.466668	up_reg	173
H4C3	P62805	2	0	1	0.336	0.581	1	90.43752	6.938438	up_reg	4
H4C8	P62805	2	5828	7	0.336	0.581	1	90.43752	2.770586	up_reg	3
H4C9	P62805	2	13910	7	0.336	0.581	1	90.43752	4.248213	up_reg	1
STAT1	P42224	2	28968	10	0.247	0.581	2	88.26074	2.024616	up_reg	12059
CA9	Q16790	2	761	2	0.253	0.580	2	76.98377	4.198252	up_reg	2015
NOS1AP	O75052	2	0	1	0.211	0.579	1	66.16135	2.421510	up_reg	221
SIGLEC14	Q08ET2	2	0	1	0.311	0.576	1	83.53957	2.119134	up_reg	49
RAD54B	Q9Y620	2	0	1	0.092	0.573	1	71.80594	2.894284	up_reg	91
GMNC	A6NCL1	2	0	1	0.280	0.572	1	59.65300	6.567087	up_reg	40
GPSM3	Q9Y4H4	2	0	1	0.281	0.570	1	71.62680	2.087401	up_reg	18
LTF	P02788	2	2076	3	0.410	0.569	1	95.06001	5.560156	up_reg	1484
FCGR1A	P12314	2	26802	5	0.350	0.568	2	84.96186	3.117302	up_reg	253
HLA-DQA2	P01906	2	761	6	0.146	0.568	1	89.47761	4.305408	up_reg	88
ELMO3	Q96BJ8	2	0	1	0.169	0.567	2	89.19677	3.013380	up_reg	22
CLDN6	P56747	2	4049	7	0.114	0.566	1	80.73011	12.449902	up_reg	114
GZMA	P12544	2	0	1	0.340	0.564	2	91.46294	2.555949	up_reg	557
MARVELD2	Q8N4S9	2	3133	5	0.305	0.564	1	67.20563	5.592913	up_reg	78
P2RY6	Q15077	43	0	1	0.257	0.563	1	85.89765	4.546917	up_reg	35
E2F8	A0AVK6	2	0	1	0.140	0.562	1	53.69316	6.360635	up_reg	151
PACSIN1	Q9BY11	2	761	2	0.285	0.562	1	85.39394	2.524601	up_reg	88
RPS6KA1	Q15418	2	3340	3	0.060	0.562	3	77.46253	2.996836	up_reg	451
ENHO	Q6UWT2	27	0	1	0.408	0.561	2	75.10782	3.532277	up_reg	183
RSPO4	Q2I0M5	37	0	2	0.197	0.559	1	78.73711	3.739053	up_reg	61
DSCC1	Q9BVC3	2	0	1	0.206	0.558	1	92.16572	2.243598	up_reg	20
KIF2C	Q99661	2	8668	7	0.070	0.558	2	74.65762	4.503661	up_reg	295
ZBP1	Q9H171	2	0	1	0.155	0.556	1	55.84276	4.315149	up_reg	389
TK1	P04183	2	28	2	0.284	0.554	2	82.30998	5.569907	up_reg	778
MAP4K1	Q92918	2	0	1	0.100	0.553	2	69.28828	2.859794	up_reg	52
NGEF	Q8N5V2	2	0	1	0.181	0.553	1	72.01310	2.849246	up_reg	50
EXO1	Q9UQ84	2	0	2	0.203	0.552	1	63.63935	4.665404	up_reg	924
SPN	P16150	2	0	1	0.297	0.552	1	53.31901	2.356560	up_reg	3261
UBE2S	Q16763	2	77901	9	0.168	0.552	1	81.85029	2.769728	up_reg	116
ALDH3B1	P43353	5	0	2	0.048	0.550	1	96.26882	2.749792	up_reg	38
MCM10	Q7L590	2	0	5	0.080	0.549	2	66.88891	4.376528	up_reg	231
PRKCQ	Q04759	2	0	1	0.202	0.549	2	79.85454	2.711625	up_reg	721
BARX2	Q9UMQ3	2	0	1	0.238	0.548	1	66.35156	7.021298	up_reg	61
TNFRSF9	Q07011	2	761	2	0.306	0.548	2	81.76231	5.502102	up_reg	554
ERCC6L	Q2NKX8	2	761	2	0.048	0.546	1	62.79458	2.571255	up_reg	62
ITGA3	P26006	2	2794	5	0.183	0.545	2	84.16933	2.090433	up_reg	228
HLA-DMB	P28068	2	0	2	0.451	0.541	1	89.04596	2.973875	up_reg	427
MICB	Q29980	2	117	2	0.152	0.538	1	78.97880	2.653896	up_reg	735
PTPN3	P26045	2	0	1	0.087	0.538	1	73.60570	2.860009	up_reg	82
CITED4	Q96RK1	2	761	2	0.279	0.537	1	61.06457	3.902872	up_reg	42
ECT2	Q9H8V3	2	463	3	0.116	0.537	1	71.66219	4.589366	up_reg	384
TTC30B	Q8N4P2	55	0	1	0.170	0.535	2	93.27146	2.933139	up_reg	4
ALOX5AP	P20292	7	0	1	0.299	0.534	1	89.60768	2.082130	up_reg	517
THEM6	Q8WUY1	2	0	1	0.187	0.534	1	94.93291	3.578714	up_reg	6
SMC4	Q9NTJ3	2	4021	6	0.294	0.533	3	81.89970	2.074392	up_reg	175
MLF1	P58340	2	799	4	0.247	0.532	1	65.94371	2.278928	up_reg	110
NDC80	O14777	2	2922	3	0.161	0.532	2	78.60958	4.044795	up_reg	592
LSR	Q86X29	2	4740	5	0.029	0.531	2	57.32796	5.010835	up_reg	1449
KRT18	P05783	2	5320	3	0.125	0.530	1	80.29975	5.341706	up_reg	409
LINGO1	Q96FE5	2	0	1	0.222	0.530	2	86.97018	3.398463	up_reg	268
TYMS	P04818	2	0	2	0.380	0.529	1	94.13606	2.197956	up_reg	818
CGN	Q9P2M7	2	0	1	0.153	0.528	1	70.80985	2.903039	up_reg	1290
IL2RB	P14784	2	377	2	0.064	0.528	1	65.81703	3.612277	up_reg	374
EGFL6	Q8IUX8	26	0	1	0.125	0.526	1	67.15563	6.860705	up_reg	84
SCNN1A	P37088	2	0	1	0.225	0.525	1	75.79274	5.496125	up_reg	300
GNGT1	P63211	2	9443	6	0.318	0.524	1	88.83912	3.959000	up_reg	29
RBBP8	Q99708	2	4708	8	0.355	0.524	1	53.50791	2.260842	up_reg	287
NELL2	Q99435	14	0	1	0.254	0.523	1	80.32717	2.349571	up_reg	103
TM4SF1	P30408	2	0	1	0.246	0.523	1	81.27962	2.530357	up_reg	151
CDK5	Q00535	2	4541	5	0.253	0.522	1	91.44164	2.814439	up_reg	3067
ESRRG	P62508	2	0	1	0.247	0.522	1	76.18379	3.288085	up_reg	338
MCM2	P49736	2	0	2	0.139	0.522	3	76.52259	2.384586	up_reg	1556
PKM	P14618	2	3037	5	0.224	0.522	2	96.78672	2.561725	up_reg	1019
LAIR1	Q6GTX8	2	174	2	0.416	0.521	1	71.90481	2.172930	up_reg	216
PTPRF	P10586	2	0	1	0.303	0.521	3	82.86021	2.388058	up_reg	139
KCTD1	Q719H9	2	0	1	0.380	0.519	1	87.09265	3.190517	up_reg	35
S100A4	P26447	2	7702	4	0.313	0.516	1	85.18673	3.072037	up_reg	1705
CENPM	Q9NSP4	2	439	4	0.181	0.514	1	89.76468	4.526135	up_reg	49
KRT15	P19012	2	4	4	0.359	0.513	1	77.14245	3.112879	up_reg	229
MPZL3	Q6UWV2	40	0	1	0.289	0.513	1	80.77116	2.509616	up_reg	25
EMB	Q6PCB8	2	2277	2	0.381	0.512	1	78.47557	2.398641	up_reg	3502
PCDH19	Q8TAB3	2	0	1	0.156	0.512	1	68.74772	2.531005	up_reg	242
DTL	Q9NZJ0	2	0	1	0.101	0.511	2	63.43932	4.651305	up_reg	625
TNFRSF13C	Q96RJ3	2	388	2	0.223	0.511	1	64.47587	2.730865	up_reg	371
PNP	P00491	46	1	2	0.189	0.507	1	94.05180	2.680894	up_reg	6777
PTPN6	P29350	2	2507	6	0.243	0.507	1	86.41216	3.217645	up_reg	1532
KIF14	Q15058	2	5312	10	0.127	0.506	1	66.04636	4.471441	up_reg	163
ITGB4	P16144	2	8018	6	0.154	0.505	1	69.97733	3.972681	up_reg	363
PTTG1	O95997	2	3399	3	0.339	0.504	1	64.54399	5.620004	up_reg	437
CDKN2A	P42771	2	761	3	0.396	0.503	2	75.59437	8.463693	up_reg	13656
LPAR3	Q9UBY5	2	0	1	0.018	0.503	1	81.89258	4.654211	up_reg	129
CDH6	P55285	2	3554	3	0.178	0.502	1	78.76359	5.541725	up_reg	108
ERBB3	P21860	2	19657	7	0.108	0.502	1	72.82537	4.895964	up_reg	2709
GIPC1	O14908	2	0	1	0.347	0.501	1	81.65762	2.472014	up_reg	174
CXCL1	P09341	2	1755	4	0.207	0.499	1	82.27114	3.026079	up_reg	6221
EVPL	Q92817	2	0	1	0.174	0.499	1	73.17542	5.384071	up_reg	34
KIF23	Q02241	2	5487	6	0.314	0.498	1	73.07353	3.446904	up_reg	207
PPARGC1B	Q86YN6	2	0	1	0.075	0.497	1	50.96161	2.110510	up_reg	252
IL12RB1	P42701	2	0	1	0.192	0.495	1	77.25548	2.276120	up_reg	347
CYRIB	Q9NUQ9	2	0	1	0.134	0.494	1	92.17381	2.720870	up_reg	15
FOXP3	Q9BZS1	2	761	2	0.090	0.491	1	58.06645	2.948779	up_reg	21309
FBP1	P09467	3	1	2	0.373	0.490	1	94.36528	3.028902	up_reg	548
WNT7A	O00755	2	761	2	0.309	0.489	1	88.75607	9.734620	up_reg	673
FGFR3	P22607	2	2641	4	0.127	0.488	1	75.36964	3.476785	up_reg	3416
ANXA3	P12429	2	0	1	0.484	0.487	1	96.34132	4.071198	up_reg	190
CDCA8	Q53HL2	2	6045	6	0.388	0.483	1	68.78919	4.987197	up_reg	205
ITGB6	P18564	2	0	1	0.064	0.481	1	83.51907	5.417491	up_reg	168
MRPL13	Q9BYD1	2	2181	4	0.371	0.481	1	93.49656	2.310295	up_reg	32
TNNC1	P63316	2	0	1	0.394	0.480	1	79.95947	2.859371	up_reg	127
CD86	P42081	2	4201	4	0.351	0.479	1	79.80962	2.860159	up_reg	12042
WNT2	P09544	2	688	2	0.340	0.478	1	88.00264	2.283292	up_reg	612
LEF1	Q9UJU2	2	4131	5	0.140	0.477	1	57.83920	3.139927	up_reg	2086
OLR1	P78380	2	0	1	0.388	0.476	1	87.40709	4.414247	up_reg	1066
CD200R1	Q8TD46	2	0	1	0.414	0.475	1	76.65146	2.587670	up_reg	259
SH3BGRL3	Q9H299	44	0	1	0.301	0.475	1	96.43171	2.275968	up_reg	34
CD38	P28907	2	2701	2	0.290	0.474	1	91.07150	2.603605	up_reg	9643
NCF1	P14598	2	1234	2	0.241	0.472	1	83.56633	2.397018	up_reg	369
CDK1	P06493	2	17675	13	0.514	0.471	1	89.31551	4.500461	up_reg	5957
LCK	P06239	2	54987	19	0.188	0.471	1	84.33331	2.329222	up_reg	3794
NDUFS8	O00217	2	0	1	0.547	0.470	1	89.19101	2.656440	up_reg	70
DEPDC1B	Q8WUY9	2	444	3	0.107	0.469	1	77.36351	4.803039	up_reg	54
CD52	P31358	2	0	1	0.352	0.466	1	68.58155	2.633993	up_reg	1238
TFF3	Q07654	2	761	2	0.405	0.466	1	80.13800	2.167937	up_reg	1057
OCLN	Q16625	2	4018	7	0.030	0.464	1	65.47618	3.942788	up_reg	1993
CNKSR1	Q969H4	2	0	1	0.212	0.463	1	68.49088	2.403831	up_reg	35
E2F3	O00716	2	761	2	-0.002	0.462	1	61.41248	2.643044	up_reg	789
SPON1	Q9HCB6	2	761	2	0.074	0.461	1	77.42394	3.386911	up_reg	119
FAM83D	Q9H4H8	2	0	1	0.140	0.459	1	64.42717	5.053814	up_reg	58
OAS1	P00973	19	0	2	0.310	0.455	1	84.21378	3.083827	up_reg	681
CLIC5	Q9NZA1	2	760	2	0.184	0.454	1	68.21008	5.435746	up_reg	79
CEBPA	P49715	2	18094	5	0.467	0.453	1	63.67368	3.364331	up_reg	1906
RAB3IP	Q96QF0	48	1	2	0.090	0.453	1	72.31525	2.494769	up_reg	30
S100A1	P23297	2	1966	2	0.469	0.452	2	82.78688	5.000700	up_reg	521
DOK7	Q18PE1	2	0	1	0.150	0.450	1	66.42315	5.786555	up_reg	193
NECTIN4	Q96NY8	2	761	2	0.112	0.450	1	78.89692	6.633982	up_reg	334
BLNK	Q8WV28	2	80581	4	0.308	0.447	1	64.71740	2.938435	up_reg	282
CXCL14	O95715	2	2123	5	0.298	0.447	1	85.46693	2.064284	up_reg	483
DEPDC1	Q5TB30	2	0	1	0.111	0.445	1	61.05036	5.973836	up_reg	91
NEIL3	Q8TAT5	2	1223	6	0.015	0.445	1	70.00855	5.418772	up_reg	151
ZNF217	O75362	2	6359	7	0.240	0.445	1	50.34735	2.073407	up_reg	219
PI3	P19957	2	58	2	0.417	0.443	1	71.76906	7.675165	up_reg	9625
ALOX5	P09917	7	0	1	0.355	0.442	1	97.15666	2.088381	up_reg	521
GRHL2	Q6ISB3	33	0	1	0.092	0.442	1	67.86823	7.179971	up_reg	231
MSX1	P28360	2	1056	2	0.339	0.442	1	65.80064	2.501717	up_reg	1214
MYH14	Q7Z406	2	0	1	0.245	0.442	1	74.65097	6.665417	up_reg	115
GINS3	Q9BRX5	2	2215	4	0.238	0.441	1	88.16138	2.227008	up_reg	28
IKBKE	Q14164	2	123	2	0.192	0.440	1	88.66232	2.971049	up_reg	1238
PPP1CA	P62136	2	17077	14	0.206	0.440	1	91.55269	2.763584	up_reg	98
PCDH7	O60245	2	0	1	0.174	0.439	1	76.89920	2.341810	up_reg	114
KRT5	P13647	2	0	4	0.423	0.438	1	68.77450	4.040272	up_reg	612
KIF18B	Q86Y91	2	764	11	0.200	0.437	1	62.74387	5.536292	up_reg	74
WAS	P42768	2	2279	3	0.258	0.437	1	70.12989	2.016246	up_reg	0
NAA38	Q9BRA0	2	0	1	0.488	0.435	1	79.30929	2.165583	up_reg	16
CA12	O43570	2	0	1	0.413	0.434	1	88.39335	3.797709	up_reg	388
COL23A1	Q86Y22	1	0	2	0.185	0.433	1	60.28518	4.830819	up_reg	30
CCL5	P13501	2	9296	3	0.141	0.432	1	89.33505	3.279413	up_reg	8493
MYO5B	Q9ULV0	41	0	1	0.304	0.432	1	75.50398	3.621753	up_reg	185
TES	Q9UGI8	2	0	1	0.196	0.431	1	86.49349	2.394874	up_reg	8760
SMKR1	H3BMG3	2	0	1	0.229	0.430	1	70.64355	5.083228	up_reg	1
STXBP2	Q15833	2	761	2	0.122	0.430	1	90.53373	2.772280	up_reg	160
FOXP4	Q8IVH2	2	0	1	0.159	0.427	1	59.23848	2.392759	up_reg	143
TNFRSF4	P43489	2	0	1	0.295	0.427	1	77.22429	2.183879	up_reg	644
GATA3	P23771	2	29626	9	0.110	0.426	1	58.31754	3.618532	up_reg	5363
HOXB6	P17509	2	0	3	0.098	0.426	1	66.54839	5.256411	up_reg	118
ORC6	Q9Y5N6	2	4900	4	0.216	0.425	1	81.54463	3.385301	up_reg	101
IFIT2	P09913	2	0	1	0.301	0.424	1	88.96310	2.135232	up_reg	254
CKS1B	P61024	2	9359	3	0.172	0.423	1	92.17249	2.929388	up_reg	191
CTNNA2	P26232	2	0	1	0.082	0.423	1	80.50284	4.876683	up_reg	94
PLS1	Q14651	2	0	2	0.067	0.423	1	87.84443	4.693588	up_reg	352
RGS1	Q08116	2	0	1	0.315	0.422	1	81.96646	2.074463	up_reg	310
BICDL2	A1A5D9	11	0	1	0.351	0.415	1	80.82586	5.705336	up_reg	0
CDKN3	Q16667	2	0	1	0.472	0.413	1	91.05949	4.403471	up_reg	184
GAPDH	P04406	2	8828	5	0.345	0.413	1	98.17071	2.454683	up_reg	8509
JPH1	Q9HDC5	2	0	1	0.144	0.413	1	66.01235	2.552469	up_reg	27
KNSTRN	Q9Y448	2	0	1	0.402	0.413	1	68.64854	2.082946	up_reg	35
OAS3	Q9Y6K5	19	0	2	0.107	0.413	2	86.81560	2.988047	up_reg	199
LLGL2	Q6P1M3	2	761	2	0.114	0.412	2	85.39241	2.400335	up_reg	46
TPD52	P55327	2	761	5	0.350	0.412	1	68.17637	4.269727	up_reg	183
GNLY	P22749	2	761	2	0.379	0.410	1	78.38773	2.553860	up_reg	401
OTUB2	Q96DC9	2	0	1	0.314	0.410	1	94.26903	2.133800	up_reg	43
NRG4	Q8WWG1	2	0	3	0.403	0.409	1	78.48852	2.336379	up_reg	130
RASSF7	Q02833	2	0	1	0.307	0.409	1	74.57045	3.298786	up_reg	42
CCL20	P78556	2	2052	2	0.403	0.405	1	89.38489	5.283080	up_reg	2596
BUB1	O43683	2	1521	3	0.138	0.403	1	64.12427	4.789490	up_reg	1284
ZC2HC1C	Q53FD0	55	0	1	0.370	0.403	1	61.17503	2.306638	up_reg	2
MRPL14	Q6P1L8	2	231	4	0.335	0.400	1	86.22027	2.510977	up_reg	12
TACC3	Q9Y6A5	2	727	2	0.259	0.400	1	58.34000	3.743070	up_reg	369
GRHL1	Q9NZI5	33	0	1	0.206	0.399	0	68.95769	3.061285	up_reg	64
HLA-DRB1	P01911	2	4530	4	0.309	0.398	0	89.12497	3.221560	up_reg	10656
MRPL15	Q9P015	2	0	2	0.439	0.396	0	91.01003	2.252783	up_reg	21
DARS2	Q6PI48	23	0	1	0.102	0.394	0	88.75458	2.268401	up_reg	103
SORT1	Q99523	2	2539	6	0.176	0.394	0	83.49614	2.686299	up_reg	283
BOP1	Q14137	13	0	1	0.149	0.393	0	80.78432	2.165984	up_reg	120
MAFB	Q9Y5Q3	2	1384	3	0.207	0.393	0	64.85064	2.002627	up_reg	701
OASL	Q15646	2	0	2	0.340	0.392	0	92.28700	5.308283	up_reg	267
CCL2	P13500	2	6612	3	0.274	0.389	0	87.56294	2.248695	up_reg	20922
SYNGR3	O43761	2	0	1	0.202	0.389	0	80.73087	2.967295	up_reg	15
SLC7A1	P30825	2	1521	3	0.129	0.387	0	81.62643	2.506855	up_reg	219
CEP55	Q53EZ4	2	640	2	0.284	0.386	0	82.79305	5.920805	up_reg	274
FBXL16	Q8N461	31	0	1	0.345	0.386	0	84.45983	4.344689	up_reg	15
MARS2	Q96GW9	4	0	1	0.093	0.386	0	89.64912	2.313493	up_reg	31
AP1S3	Q96PC3	2	11076	13	0.308	0.385	0	93.25617	3.118487	up_reg	40
KCNQ1	P51787	2	1520	2	0.165	0.385	0	68.84458	2.709769	up_reg	2537
HP	P00738	2	0	1	0.249	0.384	0	86.65695	3.617985	up_reg	99196
PTPRJ	Q12913	2	0	1	0.406	0.384	0	78.57151	2.285213	up_reg	229
UBE2T	Q9NPD8	2	0	1	0.273	0.383	0	86.02709	5.344372	up_reg	147
KRT23	Q9C075	2	1409	6	0.182	0.382	0	78.43096	7.803255	up_reg	48
LSM4	Q9Y4Z0	2	761	2	0.486	0.382	0	77.63958	2.319798	up_reg	62
TEKT2	Q9UIF3	2	0	6	0.320	0.382	0	91.10427	3.432483	up_reg	16
MMP7	P09237	2	2130	3	0.296	0.381	0	87.58781	8.418438	up_reg	3046
HLA-DQA1	P01909	2	0	6	0.385	0.380	0	88.71415	4.559819	up_reg	1989
MZB1	Q8WU39	29	0	1	0.198	0.380	0	84.76435	3.553878	up_reg	69
EIF4EBP1	Q13541	2	0	1	0.320	0.379	0	71.29362	2.070414	up_reg	1560
RRM2	P31350	2	0	1	0.276	0.377	0	80.12601	5.527053	up_reg	906
ZNF726	A6NNF4	56	0	1	0.407	0.377	0	70.98692	2.195829	up_reg	4
CDCA5	Q96FF9	2	0	1	0.258	0.376	0	63.50505	4.692774	up_reg	156
RFXANK	O14593	2	0	1	0.338	0.374	0	79.70517	2.042703	up_reg	87
KIF1A	Q12756	2	0	11	0.106	0.373	0	71.01825	4.710262	up_reg	351
SPC24	Q8NBT2	2	0	1	0.345	0.372	0	91.39337	4.999440	up_reg	79
DDAH1	O94760	2	0	1	0.378	0.370	0	95.89648	2.198679	up_reg	338
PIF1	Q9H611	2	0	1	0.062	0.368	0	77.97936	2.843531	up_reg	476
PIERCE1	Q5BN46	2	0	6	0.223	0.365	0	76.89413	3.026062	up_reg	6
TNNI1	P19237	2	1141	3	0.252	0.365	0	78.08491	4.029660	up_reg	90
SEMA3A	Q14563	2	3032	2	0.234	0.363	0	84.47667	3.102679	up_reg	1503
GNL3L	Q9NVN8	13	0	1	0.138	0.362	0	72.84667	3.254326	up_reg	26
TYROBP	O43914	2	4887	4	0.285	0.361	0	64.54930	3.691863	up_reg	602
CLDN4	O14493	2	2764	6	0.511	0.360	0	84.52154	7.966261	up_reg	627
GRB7	Q14451	2	0	1	0.214	0.360	0	78.88878	6.167946	up_reg	309
BID	P55957	2	0	1	0.136	0.357	0	62.45273	2.048675	up_reg	19500
COX7B	P24311	2	0	2	0.404	0.355	0	90.27638	2.360595	up_reg	50
FCGR2B	P31994	2	0	1	0.421	0.355	0	79.03060	2.783225	up_reg	591
NUDT14	O95848	2	0	1	0.254	0.354	0	94.66943	2.521537	up_reg	7
CENPW	Q5EE01	2	0	4	0.310	0.353	0	89.69919	3.831944	up_reg	60
KIFC1	Q9BW19	2	2554	7	0.202	0.353	0	77.88326	3.454857	up_reg	186
MISP	Q8IVT2	2	1139	2	0.227	0.353	0	54.69582	5.997961	up_reg	192
CADM3	Q8N126	2	0	1	0.379	0.350	0	84.61009	2.432258	up_reg	41
RUNX3	Q13761	2	9057	5	0.403	0.350	0	62.21557	4.881702	up_reg	1560
VAMP8	Q9BV40	2	3785	5	0.286	0.350	0	90.45868	4.647834	up_reg	317
CADM1	Q9BY67	2	1434	3	0.332	0.349	0	81.61015	2.022739	up_reg	579
CTSS	P25774	2	0	1	0.287	0.348	0	94.54174	2.821640	up_reg	564
RABIF	P47224	2	0	1	0.330	0.348	0	89.03728	2.438201	up_reg	29
FTH1	P02794	2	0	1	0.354	0.347	0	95.76727	2.083195	up_reg	545
ASF1B	Q9NVP2	2	750	3	0.391	0.346	0	85.64720	5.643420	up_reg	113
ENKUR	Q8TC29	2	0	5	0.369	0.346	0	87.21706	2.841760	up_reg	12
GREM1	O60565	12	0	1	0.032	0.346	0	73.24474	2.646893	up_reg	586
ESCO2	Q56NI9	2	0	1	0.462	0.344	0	58.41527	4.684359	up_reg	136
PPP1R16B	Q96T49	2	0	1	0.190	0.344	0	70.84716	2.196990	up_reg	45
RPL39L	Q96EH5	2	0	1	0.319	0.343	0	94.09941	3.915386	up_reg	19
SEMA3F	Q13275	2	0	1	0.253	0.342	0	84.11920	3.717983	up_reg	283
FCGR3A	P08637	2	622	3	0.351	0.341	0	85.63872	2.760408	up_reg	763
PRKCI	P41743	2	38	2	0.145	0.340	0	82.48188	2.360984	up_reg	118
JCHAIN	P01591	35	0	1	0.320	0.338	0	87.07085	3.236821	up_reg	219
PDLIM1	O00151	2	3755	2	0.426	0.336	0	70.20826	2.021676	up_reg	70
SERPINA1	P01009	2	20309	6	0.431	0.336	0	89.00521	4.107159	up_reg	1052
LAMTOR2	Q9Y2Q5	2	0	1	0.338	0.335	0	91.48972	2.013323	up_reg	73
TONSL	Q96HA7	2	0	3	0.187	0.335	0	76.48871	2.768622	up_reg	54
HLA-DRB5	Q30154	2	206	6	0.385	0.330	0	88.27784	2.841964	up_reg	548
HOXB5	P09067	2	3032	4	0.277	0.330	0	63.73337	5.327041	up_reg	195
PSMB3	P49720	2	0	1	0.327	0.330	0	97.37889	2.223922	up_reg	28
MYCN	P04198	2	6049	4	0.286	0.329	0	61.81702	2.589804	up_reg	3302
TNFAIP6	P98066	2	1198	2	0.207	0.328	0	82.64910	2.971830	up_reg	536
BCL2A1	Q16548	2	0	1	0.333	0.327	0	87.41244	2.485455	up_reg	273
MFAP5	Q13361	12	0	1	-0.012	0.327	0	65.71101	3.343997	up_reg	81
CKMT1A	P12532	8	0	1	0.049	0.325	0	90.05943	6.417662	up_reg	20
CKMT1B	P12532	8	0	1	0.049	0.325	0	90.05943	4.787301	up_reg	16
CLSPN	Q9HAW4	2	7028	7	0.285	0.322	0	51.81036	5.405931	up_reg	151
CLDN9	O95484	2	0	6	0.387	0.320	0	81.18086	7.555719	up_reg	51
ZWINT	O95229	2	4	2	0.268	0.320	0	79.45827	3.872467	up_reg	129
GINS2	Q9Y248	2	0	2	0.258	0.318	0	93.40448	2.817382	up_reg	85
RIPK3	Q9Y572	2	0	1	0.217	0.318	0	67.61724	2.151159	up_reg	1999
EME1	Q96AY2	2	1520	2	0.155	0.315	0	67.90349	2.216719	up_reg	191
TNFSF13B	Q9Y275	2	761	4	0.316	0.307	0	79.05813	2.662063	up_reg	1362
WNT11	O96014	2	0	1	0.355	0.304	0	90.30817	2.266810	up_reg	623
GMIP	Q9P107	2	0	1	0.172	0.303	0	70.24573	2.022512	up_reg	34
RTN4R	Q9BZR6	2	761	2	0.240	0.303	0	77.06296	2.676907	up_reg	339
KIF6	Q6ZMV9	2	0	12	0.091	0.302	0	71.56561	2.593490	up_reg	83
NOL4L	Q96MY1	2	0	1	0.262	0.302	0	62.45976	2.745127	up_reg	11
TP73	O15350	2	892	3	0.199	0.300	0	66.41421	3.196305	up_reg	1569
MELTF	P08582	2	0	1	0.273	0.298	0	89.73721	2.741729	up_reg	38
REC8	O95072	2	0	2	0.349	0.297	0	64.69331	3.247582	up_reg	418
E2F1	Q01094	2	10918	7	0.159	0.295	0	63.73504	2.635547	up_reg	5117
TACSTD2	P09758	2	0	1	0.332	0.294	0	82.22030	6.975909	up_reg	296
MYL11	Q96A32	2	761	2	0.286	0.293	0	84.57639	3.638218	up_reg	0
BEND3	Q5T5X7	2	0	1	0.249	0.292	0	65.37982	2.733342	up_reg	142
CXCL17	Q6UXB2	2	11398	7	0.060	0.292	0	59.53315	7.541358	up_reg	104
SALL4	Q9UJQ4	2	0	1	0.204	0.290	0	51.44781	3.878009	up_reg	846
CD4	P01730	2	3035	4	0.442	0.289	0	85.57181	2.281950	up_reg	186553
GINS1	Q14691	2	0	2	0.241	0.287	0	93.30269	3.780438	up_reg	67
SIX1	Q15475	28	2	2	0.184	0.287	0	74.01302	5.368302	up_reg	721
UBE2C	O00762	2	23230	6	0.355	0.286	0	89.69871	6.912778	up_reg	434
PPP1R1B	Q9UD71	2	0	1	0.401	0.285	0	66.04138	2.849180	up_reg	390
CCNE1	P24864	2	4140	5	0.101	0.284	0	79.97658	5.446912	up_reg	1061
KCNQ3	O43525	2	0	2	0.045	0.284	0	57.10836	3.162918	up_reg	527
CXCL9	Q07325	2	4000	3	0.304	0.283	0	87.92398	5.250589	up_reg	3397
PTK6	Q13882	2	5745	4	0.137	0.283	0	89.16695	2.218046	up_reg	248
S100A2	P29034	2	0	1	0.329	0.282	0	87.05777	5.595045	up_reg	304
TTC30A	Q86WT1	55	1	2	0.265	0.280	0	93.50527	2.528791	up_reg	3
SELPLG	Q14242	2	0	1	0.376	0.279	0	51.08547	2.634270	up_reg	66
TFAP2C	Q92754	2	2279	3	0.181	0.278	0	66.88803	5.774422	up_reg	281
EPHA1	P21709	2	4697	4	0.216	0.277	0	80.64237	4.441436	up_reg	315
PPL	O60437	2	7508	3	0.357	0.276	0	75.60075	2.018881	up_reg	2003
PSMB9	P28065	2	0	1	0.362	0.276	0	91.17994	2.788039	up_reg	173
MSLN	Q13421	2	0	1	0.171	0.275	0	79.08734	7.267283	up_reg	812
ULBP3	Q9BZM4	2	0	1	0.341	0.273	0	82.87018	4.365563	up_reg	143
OVGP1	Q12889	2	0	2	0.067	0.271	0	70.75963	2.519934	up_reg	105
CD300A	Q9UGN4	2	0	1	0.291	0.270	0	70.96770	2.052455	up_reg	124
COBL	O75128	2	0	1	0.050	0.270	0	50.28154	2.051585	up_reg	103
SPI1	P17947	2	0	2	0.383	0.269	0	65.99688	2.766086	up_reg	1314
AP1M2	Q9Y6Q5	2	7501	13	0.188	0.268	0	93.09129	8.570288	up_reg	40
ST6GALNAC5	Q9BVH7	3	0	1	0.187	0.268	0	82.09840	2.808701	up_reg	36
IL18	Q14116	2	2672	3	0.438	0.267	0	89.07080	3.642493	up_reg	16116
MUC4	Q99102	2	0	1	0.254	0.266	0	58.53420	3.542323	up_reg	1209
DSG2	Q14126	2	17165	3	0.361	0.262	0	65.83342	2.526737	up_reg	470
IL1B	P01584	2	9795	5	0.104	0.259	0	75.92467	2.915989	up_reg	9812
LCN2	P80188	2	0	1	0.140	0.259	0	91.99169	9.042459	up_reg	3659
AIMP2	Q13155	4	0	1	0.116	0.258	0	81.79153	2.483720	up_reg	94
SH2D2A	Q9NP31	2	761	2	0.085	0.258	0	62.79150	2.625689	up_reg	92
PRICKLE3	O43900	2	0	1	0.183	0.257	0	67.53085	2.181166	up_reg	13
KIF18A	Q8NI77	2	2337	10	0.186	0.256	0	67.74104	4.341757	up_reg	144
FAM167A	Q96KS9	29	0	1	0.247	0.255	0	72.66449	4.356541	up_reg	37
NACC1	Q96RE7	2	0	1	0.205	0.255	0	64.21521	3.382755	up_reg	102
E2F7	Q96AV8	2	1521	3	0.108	0.254	0	51.27249	4.380384	up_reg	224
STXBP6	Q8NFX7	52	0	1	0.123	0.254	0	87.12139	2.430172	up_reg	31
LRFN4	Q6PJG9	2	761	2	0.222	0.253	0	78.08724	2.052951	up_reg	20
EPCAM	P16422	2	77	2	0.289	0.252	0	87.50649	7.738423	up_reg	9825
TNNT1	P13805	2	0	2	0.147	0.251	0	74.97393	6.310523	up_reg	141
HDGF	P51858	26	0	1	0.359	0.250	0	68.36683	2.071828	up_reg	328
KCNK15	Q9H427	36	0	1	0.042	0.249	0	79.75423	5.076910	up_reg	19
KRT7	P08729	2	0	4	0.442	0.249	0	75.69421	7.336874	up_reg	692
BANK1	Q8NDB2	2	0	1	0.100	0.248	0	61.61418	3.730736	up_reg	117
CLDN16	Q9Y5I7	2	23	6	0.140	0.247	0	69.10264	9.609066	up_reg	118
RAD51AP1	Q96B01	2	333	5	0.122	0.242	0	58.79844	4.168726	up_reg	95
FAM181A	Q8N9Y4	2	0	1	0.330	0.241	0	60.50458	8.294660	up_reg	11
LILRB4	Q8NHJ6	2	0	2	0.423	0.240	0	66.70081	3.936863	up_reg	208
CABLES1	Q8TDN4	2	0	1	0.107	0.239	0	57.81542	2.363657	up_reg	61
FKBP1C	Q5VVH2	2	0	1	0.363	0.239	0	95.38909	2.614579	up_reg	1
TNFRSF8	P28908	2	526	2	0.196	0.238	0	61.29206	2.047671	up_reg	72
VGLL1	Q99990	2	0	1	0.305	0.237	0	58.22350	10.261579	up_reg	32
KRT14	P02533	2	0	4	0.398	0.236	0	75.92890	3.310309	up_reg	716
NTN1	O95631	2	761	2	0.246	0.236	0	88.71749	3.118007	up_reg	738
MYCL	P12524	11	0	1	0.386	0.235	0	65.02508	7.726211	up_reg	137
CDT1	Q9H211	2	761	3	0.393	0.234	0	74.90779	4.825580	up_reg	656
H2AC11	P0C0S8	2	0	1	0.416	0.234	0	91.30357	4.077578	up_reg	1
RHOV	Q96L33	2	6094	5	0.401	0.233	0	85.68690	3.846255	up_reg	86
CLDN1	O95832	2	15884	6	0.392	0.231	0	84.70039	2.942980	up_reg	1280
H2AC8	P04908	2	12365	8	0.384	0.231	0	91.08903	2.068346	up_reg	1
CXCL10	P02778	2	0	2	0.109	0.230	0	90.08511	6.235378	up_reg	8876
GRN	P28799	2	761	2	0.140	0.230	0	76.98417	2.143488	up_reg	3094
HLA-DPB1	P04440	2	0	4	0.168	0.229	0	87.13757	3.113183	up_reg	1195
SYNGR2	O43760	50	0	1	0.192	0.229	0	81.66832	2.408663	up_reg	14
CDCA4	Q9BXL8	2	2277	2	0.090	0.228	0	63.80400	2.599588	up_reg	44
MATK	P42679	2	3136	3	0.135	0.225	0	83.78212	2.482567	up_reg	1410
CDH1	P12830	2	23050	9	0.076	0.224	0	79.89055	4.933467	up_reg	5706
MPPED2	Q15777	2	0	1	0.120	0.222	0	95.36715	4.417398	up_reg	28
RSPO1	Q2MKA7	37	8	4	0.111	0.221	0	75.36365	3.025055	up_reg	350
TNFAIP2	Q03169	52	0	1	0.238	0.221	0	85.94862	2.993107	up_reg	97
UHRF1	Q96T88	2	16747	6	0.210	0.221	0	81.26714	4.080136	up_reg	696
CD48	P09326	2	761	2	0.445	0.219	0	83.72723	3.054479	up_reg	1312
PRKCZ	Q05513	2	4419	5	0.054	0.219	0	80.53423	2.469978	up_reg	130
EYA4	O95677	28	0	1	0.371	0.218	0	64.03401	3.012436	up_reg	144
CDC20	Q12834	2	13778	4	0.319	0.217	0	84.85435	6.475074	up_reg	1650
PMAIP1	Q13794	2	3032	2	0.317	0.217	0	82.91014	3.896961	up_reg	738
NRTN	Q99748	2	1521	3	0.352	0.216	0	79.04346	5.712851	up_reg	249
CDH2	P19022	2	2326	5	0.099	0.215	0	79.17653	2.559787	up_reg	1215
NHERF1	O14745	2	1521	3	0.202	0.212	0	72.47472	3.097348	up_reg	466
ITGA4	P13612	2	7750	3	0.145	0.211	0	84.56353	2.107446	up_reg	277
KRT80	Q6KB66	2	0	5	0.411	0.209	0	76.76731	5.731736	up_reg	32
MET	P08581	2	3305	3	0.093	0.209	0	79.58763	2.695561	up_reg	276508
CFAP90	A4QMS7	2	0	1	0.256	0.204	0	75.36202	2.657168	up_reg	0
LSP1	P33241	2	563	2	0.145	0.204	0	60.56910	2.311015	up_reg	316
ARL11	Q969Q4	2	0	1	0.147	0.203	0	88.13514	3.125100	up_reg	38
DNMT3B	Q9UBC3	2	56	2	0.077	0.203	0	73.57543	2.148336	up_reg	2407
SDC1	P18827	2	4415	6	0.400	0.203	0	55.99303	4.335717	up_reg	1549
HOXB4	P17483	2	0	3	0.094	0.202	0	68.07405	4.785876	up_reg	429
MAP7	Q14244	2	0	1	0.366	0.202	0	62.54288	3.092922	up_reg	94
UQCRFS1	P47985	2	0	1	0.381	0.202	0	81.75593	2.088377	up_reg	57
IL1RN	P18510	2	0	1	0.197	0.201	0	87.13193	4.132662	up_reg	3592
TRIB1	Q96RU8	2	0	1	0.268	0.201	0	77.94675	2.875736	up_reg	271
HLA-DQB1	P01920	2	13782	6	0.257	0.200	0	87.11210	4.148044	up_reg	3668
SPINT1	O43278	51	0	1	0.107	0.200	0	77.01837	6.141109	up_reg	238
KRT19	P08727	2	1083	4	0.374	0.199	0	81.40007	3.098124	up_reg	448
PLK4	O00444	2	767	3	0.133	0.199	0	66.92294	2.644551	up_reg	485
POLR2F	P61218	2	3038	7	0.081	0.195	0	79.10277	4.942004	up_reg	32
CKS2	P33552	2	0	1	0.368	0.194	0	92.87122	4.440040	up_reg	168
LTB	Q06643	2	1331	3	0.279	0.194	0	78.39808	5.296640	up_reg	2405
PARS2	Q7L3T8	2	0	1	0.407	0.194	0	88.46743	2.174840	up_reg	24
S100A9	P06702	2	2897	5	0.328	0.187	0	94.90595	2.289678	up_reg	2190
SH2B2	O14492	2	0	2	0.200	0.184	0	64.23783	2.606184	up_reg	59
APLP1	P51693	2	0	1	0.120	0.183	0	69.72252	4.237735	up_reg	286
CCL28	Q9NRJ3	2	7221	4	0.193	0.182	0	73.22394	3.991313	up_reg	357
HMGA1	P17096	2	1520	2	0.159	0.181	0	65.46237	6.591907	up_reg	1299
SOX17	Q9H6I2	2	6	2	0.278	0.181	0	59.27884	4.879374	up_reg	1021
ARL4C	P56559	2	0	1	0.393	0.180	0	93.52089	4.733473	up_reg	65
PCBD1	P61457	2	0	1	0.378	0.180	0	96.56937	2.014142	up_reg	30
DOK5	Q9P104	2	0	1	0.200	0.179	0	78.36019	5.673957	up_reg	38
CXCL11	O14625	2	1773	3	0.353	0.178	0	77.92419	7.143297	up_reg	1585
CHAC2	Q8WUX2	17	0	1	0.084	0.176	0	93.52453	2.630675	up_reg	16
NDUFA4L2	Q9NRX3	2	9789	8	0.201	0.175	0	84.63933	2.341067	up_reg	53
WWC1	Q8IX03	2	3714	3	0.055	0.175	0	61.50142	5.147188	up_reg	174
LRP8	Q14114	2	1520	2	0.423	0.171	0	73.62178	2.246711	up_reg	139
KSR2	Q6VAB6	2	0	1	0.284	0.169	0	61.41177	5.960690	up_reg	79
C4orf48	Q5BLP8	14	0	1	0.365	0.167	0	78.23739	4.028170	up_reg	3
PCLAF	Q15004	2	0	1	0.264	0.167	0	66.12640	5.401491	up_reg	103
CLEC5A	Q9NY25	2	348	2	0.252	0.165	0	85.45138	2.904175	up_reg	115
NMU	P48645	2	0	1	0.141	0.161	0	63.72954	8.371797	up_reg	1511
EXOSC4	Q9NPD3	2	0	1	0.335	0.159	0	89.83185	2.636612	up_reg	25
BORA	Q6PGQ7	2	0	1	0.259	0.158	0	50.73243	2.025953	up_reg	4796
NDUFB3	O43676	2	0	1	0.294	0.157	0	86.46141	2.013948	up_reg	28
CCL8	P80075	2	0	2	0.258	0.153	0	89.58629	3.845029	up_reg	703
CLDN7	O95471	2	1242	6	0.254	0.152	0	82.24946	6.596419	up_reg	302
IFIT3	O14879	2	5526	3	0.158	0.152	0	75.74696	2.375046	up_reg	344
GALNT5	Q7Z7M9	2	0	1	0.076	0.151	0	69.18376	3.327325	up_reg	15
PDZK1IP1	Q13113	2	761	2	0.247	0.145	0	65.20753	7.379819	up_reg	81
ESPN	B1AK53	2	3036	5	0.114	0.144	0	68.30997	7.443990	up_reg	202
RGCC	Q9H4X1	2	0	1	0.314	0.141	0	71.58154	2.366748	up_reg	128
COL9A2	Q14055	1	0	3	0.053	0.140	0	55.63427	4.196349	up_reg	167
KLK8	O60259	2	0	1	0.329	0.140	0	88.53643	7.914436	up_reg	184
POMK	Q9H5K3	2	761	2	0.236	0.139	0	91.65736	5.585370	up_reg	24
TNFRSF21	O75509	2	2279	3	0.215	0.137	0	69.40738	2.418514	up_reg	172
CHI3L1	P36222	2	761	3	0.134	0.135	0	94.99146	4.967392	up_reg	1596
COX6B1	P14854	2	13	2	0.393	0.135	0	94.90168	2.489263	up_reg	35
FOXQ1	Q9C009	2	0	1	0.151	0.132	0	62.11694	8.570065	up_reg	207
PITX1	P78337	2	0	1	0.326	0.132	0	63.26645	4.758002	up_reg	479
RAB25	P57735	41	0	1	0.148	0.130	0	87.08353	7.156164	up_reg	189
CDKN2B	P42772	2	0	1	0.321	0.128	0	90.76140	2.453778	up_reg	2033
CLIC3	O95833	20	0	1	0.143	0.127	0	94.15899	4.900396	up_reg	48
CARD11	Q9BXL7	2	761	2	0.121	0.124	0	72.04895	2.481919	up_reg	557
ESM1	Q9NQ30	2	0	1	0.181	0.124	0	73.14345	3.038808	up_reg	509
TUBB4A	P04350	2	2031	4	0.190	0.124	0	92.24309	3.282229	up_reg	118
ITGB7	P26010	2	2752	2	0.268	0.121	0	82.84386	3.324527	up_reg	73
POU5F1	Q01860	2	14481	8	0.257	0.119	0	66.34535	3.740793	up_reg	3858
TNF	P01375	2	6688	6	0.273	0.119	0	85.00767	6.265458	up_reg	221351
LILRB1	Q8NHL6	2	1319	3	0.177	0.118	0	73.03943	2.334817	up_reg	396
VAV3	Q9UKW4	2	68848	8	0.067	0.117	0	84.41551	4.547079	up_reg	321
FEN1	P39748	2	0	3	0.078	0.113	0	90.03506	2.230667	up_reg	874
TMEM30B	Q3MIR4	9	0	1	0.223	0.113	0	92.35448	3.021734	up_reg	13
KRT16	P08779	2	2509	5	0.333	0.106	0	74.43273	4.141592	up_reg	182
SH3RF2	Q8TEC5	2	0	1	0.059	0.105	0	57.59249	2.729593	up_reg	18
CLU	P10909	2	1521	5	0.158	0.104	0	76.87086	2.491979	up_reg	2364
ESRP2	Q9H6T0	2	0	1	0.052	0.103	0	74.32537	4.950124	up_reg	77
SKA1	Q96BD8	2	3740	3	0.218	0.102	0	85.82242	5.476597	up_reg	114
COX5B	P10606	2	41	3	0.105	0.096	0	85.69271	2.427432	up_reg	136
RIPK4	P57078	2	15	2	0.135	0.096	0	74.60517	6.184659	up_reg	100
ISG15	P05161	2	10014	6	0.503	0.095	0	86.54014	4.583876	up_reg	1808
LYZ	P61626	2	0	1	0.190	0.093	0	94.45464	3.176699	up_reg	688
SFN	P31947	2	73299	6	0.296	0.091	0	93.38504	5.327039	up_reg	2478
HMGA2	P52926	2	761	2	0.202	0.089	0	65.13682	5.165815	up_reg	1858
CARD9	Q9H257	2	0	1	0.125	0.087	0	81.15426	3.240362	up_reg	539
CDCA7	Q9BWT1	2	0	1	0.158	0.087	0	66.71299	3.825804	up_reg	85
FAAP24	Q9BTP7	2	761	2	0.199	0.087	0	90.18733	2.416477	up_reg	35
CHMP4C	Q96CF2	2	0	1	0.263	0.083	0	77.35806	4.735938	up_reg	64
GDF15	Q99988	2	0	1	0.062	0.082	0	75.41460	2.195446	up_reg	2514
LRFN1	Q9P244	2	1520	3	0.146	0.082	0	70.58550	3.127358	up_reg	11
CSF2RA	P15509	2	0	1	0.110	0.079	0	82.07854	2.326266	up_reg	117
E2F2	Q14209	2	0	1	0.180	0.079	0	64.08260	5.446447	up_reg	639
H2AX	P16104	2	8754	10	0.328	0.078	0	87.32992	2.528322	up_reg	7218
ILDR2	Q71H61	2	0	1	0.046	0.075	0	56.53694	2.554303	up_reg	23
CCNB2	O95067	2	21505	5	0.089	0.073	0	80.38333	4.940087	up_reg	453
SPP1	P10451	2	2257	2	0.312	0.072	0	53.13979	5.389308	up_reg	4958
ILDR1	Q86SU0	2	0	1	0.115	0.071	0	58.96387	8.292796	up_reg	49
CCNF	P41002	2	0	1	0.276	0.059	0	72.44700	2.582579	up_reg	183
COL10A1	Q03692	1	5	4	-0.010	0.058	0	61.49775	4.041689	up_reg	679
PPP2R2B	Q00005	2	3032	3	0.106	0.055	0	90.41175	3.664496	up_reg	113
SGO1	Q5FBB7	2	0	1	0.108	0.050	0	55.17324	5.338592	up_reg	255
NKD2	Q969F2	2	0	1	0.151	0.047	0	56.92392	2.149191	up_reg	86
RAP1GAP	P47736	2	2277	2	0.060	0.047	0	70.99696	3.713069	up_reg	184
SKAP1	Q86WV1	2	0	1	0.224	0.046	0	71.43923	5.275064	up_reg	75
COL26A1	Q96A83	1	8	5	0.004	0.044	0	60.65501	3.863487	up_reg	8
TGM1	P22735	2	1487	3	0.097	0.042	0	85.13601	2.974339	up_reg	253
WDR93	Q6P2C0	2	3795	6	0.147	0.041	0	76.99177	2.267609	up_reg	2
COL22A1	Q8NFW1	1	0	3	0.106	0.037	0	54.74523	2.383929	up_reg	58
EPS8L1	Q8TE68	2	0	1	0.064	0.026	0	75.61647	5.101489	up_reg	11
DYRK1B	Q9Y463	25	0	1	0.097	0.022	0	74.53225	2.195558	up_reg	164
HOXB7	P09629	2	761	4	-0.001	0.021	0	66.86952	5.290210	up_reg	318
JUP	P14923	2	14648	4	0.091	0.021	0	81.10563	2.578337	up_reg	484
MAD2L1	Q13257	2	3785	3	0.178	0.019	0	93.75853	3.426759	up_reg	681
C15orf48	Q9C002	2	0	2	0.212	0.018	0	89.84824	5.134800	up_reg	21
SYTL1	Q8IYJ3	2	3037	4	0.036	0.011	0	72.77781	4.342698	up_reg	40
DUSP23	Q9BVJ7	2	0	1	0.465	0.001	0	97.64673	2.213370	up_reg	17

# dont need it, doenst work

subset_genes <- as.data.frame(pcsf_master$gene_id)
colnames(subset_genes)[1] <- "gene_id"

network_out_genes <- anti_join(uniprot_id, subset_genes, by = "gene_id")

kable(network_out_genes, format = "html", caption = "Removed genes from cytoscape + network + druggability filters") %>%
kable_styling(full_width = FALSE) %>%
scroll_box(height = "400px")

Step 4: Functional Enrichment Analysis

Show code

##   Performing enrichment analysis...

## Warning in cluster_edge_betweenness(subnet): At
## core/community/edge_betweenness.c:493 : Membership vector will be selected
## based on the highest modularity score.

##   Enrichment is being performed by EnrichR (http://amp.pharm.mssm.edu/Enrichr) API ...
## [1] "Number of enrichment results: 83"

Tip: Hover over nodes for details!

Note: P-value represents likelihood of observing that pathway by random chance. The top 15 functional enrichment terms for each cluster are ranked according to the adjusted p-value. This is what you observe when you hover your mouse over a node in that cluster.

Tabulated format

Enrichment Results

Cluster	Term	PValue	Adjusted_Pvalue	Genes
1	collagen catabolic process (GO:0030574)	0.0000000	0.0000000	COL26A1;COL13A1;COL23A1;COL10A1;COL9A2
1	multicellular organismal catabolic process (GO:0044243)	0.0000000	0.0000000	COL26A1;COL13A1;COL23A1;COL10A1;COL9A2
1	collagen metabolic process (GO:0032963)	0.0000000	0.0000000	COL26A1;COL13A1;COL23A1;COL10A1;COL9A2
1	multicellular organismal macromolecule metabolic process (GO:0044259)	0.0000000	0.0000000	COL26A1;COL13A1;COL23A1;COL10A1;COL9A2
1	multicellular organismal metabolic process (GO:0044236)	0.0000000	0.0000000	COL26A1;COL13A1;COL23A1;COL10A1;COL9A2
1	extracellular matrix disassembly (GO:0022617)	0.0000000	0.0000000	COL26A1;COL13A1;COL23A1;COL10A1;COL9A2
1	extracellular matrix organization (GO:0030198)	0.0000000	0.0000000	COL26A1;COL13A1;COL22A1;COL23A1;COL10A1;COL9A2
1	extracellular structure organization (GO:0043062)	0.0000000	0.0000000	COL26A1;COL13A1;COL22A1;COL23A1;COL10A1;COL9A2
1	cellular component disassembly (GO:0022411)	0.0000000	0.0000001	COL26A1;COL13A1;COL23A1;COL10A1;COL9A2
1	Protein digestion and absorption Homo sapiens hsa04974	0.0000000	0.0000001	COL13A1;COL22A1;COL10A1;COL9A2
1	Collagen biosynthesis and modifying enzymes Homo sapiens R-HSA-1650814	0.0000000	0.0000000	COL26A1;COL13A1;COL22A1;COL23A1;COL10A1;COL9A2
1	Collagen formation Homo sapiens R-HSA-1474290	0.0000000	0.0000000	COL26A1;COL13A1;COL22A1;COL23A1;COL10A1;COL9A2
1	Extracellular matrix organization Homo sapiens R-HSA-1474244	0.0000000	0.0000000	COL26A1;COL13A1;COL22A1;COL23A1;COL10A1;COL9A2
1	Collagen degradation Homo sapiens R-HSA-1442490	0.0000000	0.0000000	COL26A1;COL13A1;COL23A1;COL9A2
1	Degradation of the extracellular matrix Homo sapiens R-HSA-1474228	0.0000000	0.0000001	COL26A1;COL13A1;COL23A1;COL9A2
1	Integrin cell surface interactions Homo sapiens R-HSA-216083	0.0000012	0.0000029	COL13A1;COL23A1;COL9A2
2	taxis (GO:0042330)	0.0000000	0.0000182	CCL20;CCL5;CCL4;SAA1;APOA1;ACKR2;CCL28
2	chemotaxis (GO:0006935)	0.0000000	0.0000182	CCL20;CCL5;CCL4;SAA1;APOA1;ACKR2;CCL28
2	inflammatory response (GO:0006954)	0.0000005	0.0001371	CCL20;CCL5;CCL4;SAA1;SDC1;ACKR2;ASS1
2	cell chemotaxis (GO:0060326)	0.0000018	0.0003760	CCL20;CCL5;CCL4;SAA1;CCL28
2	positive regulation of cell adhesion (GO:0045785)	0.0000030	0.0004874	SDC4;CCL5;SAA1;APOA1;CCL28
2	positive regulation of lymphocyte migration (GO:2000403)	0.0000044	0.0005507	CCL20;CCL5;CCL4
2	regulation of cell adhesion (GO:0030155)	0.0000047	0.0005507	SDC4;CCL5;SAA1;APOA1;CCL28;ASS1
2	regulation of cell-cell adhesion (GO:0022407)	0.0000074	0.0007539	CCL5;APOA1;CCL28;ASS1
2	regulation of lymphocyte migration (GO:2000401)	0.0000106	0.0009612	CCL20;CCL5;CCL4
2	regulation of leukocyte migration (GO:0002685)	0.0000138	0.0011251	CCL20;CCL5;CCL4;CCL28
2	negative regulation of cell-cell adhesion (GO:0022408)	0.0000226	0.0015264	APOA1;CCL28;ASS1
2	sterol transport (GO:0015918)	0.0000243	0.0015264	MSR1;APOA1;CLU
2	cholesterol transport (GO:0030301)	0.0000243	0.0015264	MSR1;APOA1;CLU
2	lipoprotein metabolic process (GO:0042157)	0.0000280	0.0016322	AMN;APOA1;SDC1
2	response to toxic substance (GO:0009636)	0.0000376	0.0020480	CCL5;CCL4;SDC1;ASS1
2	receptor-mediated endocytosis (GO:0006898)	0.0000491	0.0025047	MSR1;AMN;APOBR;ACKR2
2	tube development (GO:0035295)	0.0000660	0.0031688	SDC4;WNT7A;SDC1;ASS1
2	response to steroid hormone (GO:0048545)	0.0001202	0.0050582	APOA1;WNT7A;SDC1;PPARGC1B;ASS1
2	lipid transport (GO:0006869)	0.0001240	0.0050582	MSR1;APOA1;APOBR;CLU
2	positive regulation of leukocyte migration (GO:0002687)	0.0001560	0.0058647	CCL20;CCL5;CCL4
2	retinoid metabolic process (GO:0001523)	0.0001745	0.0061911	SDC4;APOA1;SDC1
2	myeloid leukocyte activation (GO:0002274)	0.0002084	0.0065167	CCL5;ACKR2;CLU
2	diterpenoid metabolic process (GO:0016101)	0.0002156	0.0065167	SDC4;APOA1;SDC1
2	phototransduction, visible light (GO:0007603)	0.0002306	0.0067065	SDC4;APOA1;SDC1
2	response to cAMP (GO:0051591)	0.0002383	0.0067065	SDC1;PPARGC1B;ASS1
2	positive regulation of cell-substrate adhesion (GO:0010811)	0.0002626	0.0069234	SDC4;APOA1;CCL28
2	terpenoid metabolic process (GO:0006721)	0.0002973	0.0069234	SDC4;APOA1;SDC1
2	positive regulation of cellular component biogenesis (GO:0044089)	0.0003285	0.0069234	SDC4;APOA1;WNT7A;CLU
2	response to virus (GO:0009615)	0.0003336	0.0069234	EXOSC4;CCL5;CCL4;CLU
2	response to other organism (GO:0051707)	0.0003413	0.0069234	EXOSC4;CCL20;CCL5;CCL4;CLU
2	organic hydroxy compound transport (GO:0015850)	0.0003446	0.0069234	MSR1;APOA1;CLU
2	detection of visible light (GO:0009584)	0.0003648	0.0069234	SDC4;APOA1;SDC1
2	phototransduction (GO:0007602)	0.0004187	0.0075926	SDC4;APOA1;SDC1
2	isoprenoid metabolic process (GO:0006720)	0.0004774	0.0081166	SDC4;APOA1;SDC1
2	negative regulation of cell adhesion (GO:0007162)	0.0004898	0.0081566	APOA1;CCL28;ASS1
2	response to organophosphorus (GO:0046683)	0.0005281	0.0086181	SDC1;PPARGC1B;ASS1
2	detection of light stimulus (GO:0009583)	0.0005682	0.0090914	SDC4;APOA1;SDC1
2	response to glucocorticoid (GO:0051384)	0.0007002	0.0109879	SDC1;PPARGC1B;ASS1
2	response to purine-containing compound (GO:0014074)	0.0007320	0.0112696	SDC1;PPARGC1B;ASS1
2	response to light stimulus (GO:0009416)	0.0008638	0.0120850	SDC4;NMU;APOA1;SDC1
2	response to corticosteroid (GO:0031960)	0.0008682	0.0120850	SDC1;PPARGC1B;ASS1
2	endocytosis (GO:0006897)	0.0008738	0.0120850	MSR1;AMN;APOBR;ACKR2
2	regulation of cell-substrate adhesion (GO:0010810)	0.0010395	0.0139060	SDC4;APOA1;CCL28
2	response to nutrient (GO:0007584)	0.0013463	0.0161559	APOA1;CCL28;ASS1
2	response to estrogen (GO:0043627)	0.0014187	0.0167776	APOA1;WNT7A;ASS1
2	detection of external stimulus (GO:0009581)	0.0016504	0.0179559	SDC4;APOA1;SDC1
2	detection of abiotic stimulus (GO:0009582)	0.0017325	0.0183604	SDC4;APOA1;SDC1
2	secretion by cell (GO:0032940)	0.0021968	0.0229823	CCL5;APOA1;WNT7A;CLU
2	platelet activation (GO:0030168)	0.0025891	0.0254539	SAA1;APOA1;CLU
2	response to radiation (GO:0009314)	0.0027598	0.0268098	SDC4;NMU;APOA1;SDC1
2	gland development (GO:0048732)	0.0031604	0.0286545	APOA1;LSR;ASS1
2	exocytosis (GO:0006887)	0.0037138	0.0325857	CCL5;APOA1;CLU
2	regulation of inflammatory response (GO:0050727)	0.0043724	0.0375563	CCL5;SAA1;APOA1
2	cellular protein complex assembly (GO:0043623)	0.0048309	0.0394205	AIFM1;CCL5;CLU
2	cellular calcium ion homeostasis (GO:0006874)	0.0050979	0.0407829	CCL5;SAA1;CCL28
2	cellular divalent inorganic cation homeostasis (GO:0072503)	0.0056581	0.0443945	CCL5;SAA1;CCL28
2	calcium ion homeostasis (GO:0055074)	0.0058332	0.0449043	CCL5;SAA1;CCL28
2	positive regulation of cell migration (GO:0030335)	0.0061929	0.0467911	CCL20;CCL5;CCL4
2	positive regulation of cell motility (GO:2000147)	0.0066292	0.0473597	CCL20;CCL5;CCL4
2	response to nutrient levels (GO:0031667)	0.0068866	0.0480296	APOA1;CCL28;ASS1
2	divalent inorganic cation homeostasis (GO:0072507)	0.0068866	0.0480296	CCL5;SAA1;CCL28
2	positive regulation of cellular component movement (GO:0051272)	0.0072166	0.0497379	CCL20;CCL5;CCL4
2	positive regulation of locomotion (GO:0040017)	0.0077641	0.0522769	CCL20;CCL5;CCL4
2	response to extracellular stimulus (GO:0009991)	0.0084087	0.0540278	APOA1;CCL28;ASS1
2	sulfur compound metabolic process (GO:0006790)	0.0084823	0.0540744	SDC4;PIPOX;SDC1
2	regulation of response to wounding (GO:1903034)	0.0111250	0.0613001	CCL5;SAA1;APOA1
2	cellular metal ion homeostasis (GO:0006875)	0.0123752	0.0623342	CCL5;SAA1;CCL28
2	leukocyte activation (GO:0045321)	0.0135089	0.0629902	CCL5;ACKR2;CLU
2	cellular cation homeostasis (GO:0030003)	0.0151108	0.0655872	CCL5;SAA1;CCL28
2	cellular ion homeostasis (GO:0006873)	0.0164888	0.0682988	CCL5;SAA1;CCL28
2	metal ion homeostasis (GO:0055065)	0.0187439	0.0701605	CCL5;SAA1;CCL28
2	posttranscriptional regulation of gene expression (GO:0010608)	0.0206664	0.0703815	CCL5;APOA1;CLU
2	cellular chemical homeostasis (GO:0055082)	0.0224355	0.0721874	CCL5;SAA1;CCL28
2	positive regulation of protein kinase activity (GO:0045860)	0.0229559	0.0721874	SDC4;CCL5;CLU
2	cation homeostasis (GO:0055080)	0.0241509	0.0721874	CCL5;SAA1;CCL28
2	cellular response to cytokine stimulus (GO:0071345)	0.0249663	0.0736195	CCL5;ACKR2;ASS1
2	positive regulation of kinase activity (GO:0033674)	0.0262174	0.0750406	SDC4;CCL5;CLU
2	regulation of cytokine production (GO:0001817)	0.0265000	0.0750406	SAA1;APOA1;CLU
2	Chemokine signaling pathway Homo sapiens hsa04062	0.0001098	0.0054878	CCL20;CCL5;CCL4;CCL28
2	Cytokine-cytokine receptor interaction Homo sapiens hsa04060	0.0004159	0.0103977	CCL20;CCL5;CCL4;CCL28
2	Proteoglycans in cancer Homo sapiens hsa05205	0.0025182	0.0419693	SDC4;WNT7A;SDC1
2	Peptide ligand-binding receptors Homo sapiens R-HSA-375276	0.0000000	0.0000007	CCL20;CCL5;CCL4;NMU;SAA1;ACKR2;CCL28
2	Chemokine receptors bind chemokines Homo sapiens R-HSA-380108	0.0000000	0.0000007	CCL20;CCL5;CCL4;ACKR2;CCL28
2	GPCR ligand binding Homo sapiens R-HSA-500792	0.0000001	0.0000038	CCL20;CCL5;CCL4;NMU;SAA1;WNT7A;ACKR2;CCL28
2	Class A/1 (Rhodopsin-like receptors) Homo sapiens R-HSA-373076	0.0000002	0.0000057	CCL20;CCL5;CCL4;NMU;SAA1;ACKR2;CCL28
2	Lipoprotein metabolism Homo sapiens R-HSA-174824	0.0000128	0.0003176	AMN;APOA1;SDC1
2	G alpha (i) signalling events Homo sapiens R-HSA-418594	0.0000155	0.0003176	CCL20;CCL5;NMU;SAA1;CCL28
2	Retinoid metabolism and transport Homo sapiens R-HSA-975634	0.0000243	0.0003860	SDC4;APOA1;SDC1
2	Signal Transduction Homo sapiens R-HSA-162582	0.0000347	0.0004900	SDC4;CCL20;CCL5;CCL4;NMU;SAA1;APOA1;WNT7A;SDC1;ACKR2;NOTUM;CCL28
2	Metabolism of fat-soluble vitamins Homo sapiens R-HSA-6806667	0.0000438	0.0005110	SDC4;APOA1;SDC1
2	Metabolism of vitamins and cofactors Homo sapiens R-HSA-196854	0.0000443	0.0005110	AMN;SDC4;APOA1;SDC1
2	Lipid digestion, mobilization, and transport Homo sapiens R-HSA-73923	0.0001180	0.0010700	AMN;APOA1;SDC1
2	Binding and Uptake of Ligands by Scavenger Receptors Homo sapiens R-HSA-2173782	0.0001334	0.0011296	MSR1;SAA1;APOA1
2	Signaling by GPCR Homo sapiens R-HSA-372790	0.0002188	0.0016414	CCL20;CCL5;CCL4;NMU;SAA1;WNT7A;ACKR2;CCL28
2	Visual phototransduction Homo sapiens R-HSA-2187338	0.0002973	0.0016414	SDC4;APOA1;SDC1
2	GPCR downstream signaling Homo sapiens R-HSA-388396	0.0092926	0.0333015	CCL20;CCL5;NMU;SAA1;CCL28
2	Metabolism of lipids and lipoproteins Homo sapiens R-HSA-556833	0.0112188	0.0333169	AMN;APOA1;SDC1;PPARGC1B
2	Metabolism Homo sapiens R-HSA-1430728	0.0114279	0.0333169	AMN;SDC4;APOA1;PIPOX;SDC1;PPARGC1B;ASS1
2	Vesicle-mediated transport Homo sapiens R-HSA-5653656	0.0279378	0.0602371	MSR1;SAA1;APOA1
2	Metabolism of proteins Homo sapiens R-HSA-392499	0.0542533	0.0966115	EXOSC4;SAA1;APOA1;NUDT14
2	Disease Homo sapiens R-HSA-1643685	0.0728644	0.1156722	AMN;SDC4;SDC1
2	Immune System Homo sapiens R-HSA-168256	0.3480920	0.3594120	SAA1;FCGR2B;CLU
3	Metabolic pathways Homo sapiens hsa01100	0.0002372	0.0026092	FBP1;ACOT4;ST6GALNAC5
4	antigen processing and presentation of exogenous peptide antigen via MHC class II (GO:0019886)	0.0000000	0.0000000	CD74;HLA-DRB5;CTSS;HLA-DMA;HLA-DMB;HLA-DPB1;HLA-DRA;AP1S3;HLA-DOA;HLA-DQA2;HLA-DQB2;AP1M2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	antigen processing and presentation of peptide antigen via MHC class II (GO:0002495)	0.0000000	0.0000000	CD74;HLA-DRB5;CTSS;HLA-DMA;HLA-DMB;HLA-DPB1;HLA-DRA;AP1S3;HLA-DOA;HLA-DQA2;HLA-DQB2;AP1M2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II (GO:0002504)	0.0000000	0.0000000	CD74;HLA-DRB5;CTSS;HLA-DMA;HLA-DMB;HLA-DPB1;HLA-DRA;AP1S3;HLA-DOA;HLA-DQA2;HLA-DQB2;AP1M2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	antigen receptor-mediated signaling pathway (GO:0050851)	0.0000000	0.0000000	VAV3;HLA-DRB5;TRAC;WAS;THY1;CD3E;LCK;HLA-DPB1;HLA-DRA;HLA-DQA2;HLA-DQB2;SKAP1;HLA-DQA1;SH2B2;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	regulation of T cell activation (GO:0050863)	0.0000000	0.0000000	CD86;CD74;HLA-DRB5;TRAC;RORC;THY1;CD3E;VAV1;HLA-DMA;HLA-DMB;LCK;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	regulation of leukocyte activation (GO:0002694)	0.0000000	0.0000000	CD86;VAV3;CD74;HLA-DRB5;TRAC;STXBP2;RORC;THY1;CD3E;VAV1;HLA-DMA;HLA-DMB;LCK;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	positive regulation of T cell activation (GO:0050870)	0.0000000	0.0000000	CD86;CD74;HLA-DRB5;TRAC;THY1;CD3E;VAV1;HLA-DMA;HLA-DMB;LCK;HLA-DPB1;HLA-DRA;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	regulation of lymphocyte activation (GO:0051249)	0.0000000	0.0000000	CD86;VAV3;CD74;HLA-DRB5;TRAC;RORC;THY1;CD3E;VAV1;HLA-DMA;HLA-DMB;LCK;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	positive regulation of lymphocyte activation (GO:0051251)	0.0000000	0.0000000	CD86;VAV3;CD74;HLA-DRB5;TRAC;THY1;CD3E;VAV1;HLA-DMA;HLA-DMB;LCK;HLA-DPB1;HLA-DRA;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	T cell receptor signaling pathway (GO:0050852)	0.0000000	0.0000000	HLA-DRB5;TRAC;WAS;THY1;CD3E;LCK;HLA-DPB1;HLA-DRA;HLA-DQA2;HLA-DQB2;SKAP1;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	regulation of cell activation (GO:0050865)	0.0000000	0.0000000	CD86;VAV3;CD74;HLA-DRB5;TRAC;STXBP2;RORC;THY1;CD3E;VAV1;HLA-DMA;HLA-DMB;LCK;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	T cell costimulation (GO:0031295)	0.0000000	0.0000000	CD86;HLA-DRB5;TRAC;CD3E;VAV1;LCK;HLA-DPB1;HLA-DRA;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	lymphocyte costimulation (GO:0031294)	0.0000000	0.0000000	CD86;HLA-DRB5;TRAC;CD3E;VAV1;LCK;HLA-DPB1;HLA-DRA;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	antigen processing and presentation of exogenous peptide antigen (GO:0002478)	0.0000000	0.0000000	CD74;HLA-DRB5;CTSS;HLA-DMA;HLA-DMB;HLA-DPB1;HLA-DRA;AP1S3;HLA-DOA;FCGR1A;HLA-DQA2;HLA-DQB2;AP1M2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	antigen processing and presentation of exogenous antigen (GO:0019884)	0.0000000	0.0000000	CD74;HLA-DRB5;CTSS;HLA-DMA;HLA-DMB;HLA-DPB1;HLA-DRA;AP1S3;HLA-DOA;FCGR1A;HLA-DQA2;HLA-DQB2;AP1M2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	positive regulation of leukocyte activation (GO:0002696)	0.0000000	0.0000000	CD86;VAV3;CD74;HLA-DRB5;TRAC;THY1;CD3E;VAV1;HLA-DMA;HLA-DMB;LCK;HLA-DPB1;HLA-DRA;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	immune response-activating signal transduction (GO:0002757)	0.0000000	0.0000000	CD86;VAV3;HLA-DRB5;TRAC;WAS;THY1;CD3E;CTSS;VAV1;FCGR3A;LCK;HLA-DPB1;HLA-DRA;FCGR1A;HLA-DQA2;HLA-DQB2;SKAP1;HLA-DQA1;SH2B2;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	immune response-activating cell surface receptor signaling pathway (GO:0002429)	0.0000000	0.0000000	VAV3;HLA-DRB5;TRAC;WAS;THY1;CD3E;VAV1;FCGR3A;LCK;HLA-DPB1;HLA-DRA;FCGR1A;HLA-DQA2;HLA-DQB2;SKAP1;HLA-DQA1;SH2B2;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	positive regulation of cell activation (GO:0050867)	0.0000000	0.0000000	CD86;VAV3;CD74;HLA-DRB5;TRAC;THY1;CD3E;VAV1;HLA-DMA;HLA-DMB;LCK;HLA-DPB1;HLA-DRA;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	antigen processing and presentation of peptide antigen (GO:0048002)	0.0000000	0.0000000	CD74;HLA-DRB5;CTSS;HLA-DMA;HLA-DMB;HLA-DPB1;HLA-DRA;AP1S3;HLA-DOA;FCGR1A;HLA-DQA2;HLA-DQB2;AP1M2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	activation of immune response (GO:0002253)	0.0000000	0.0000000	CD86;VAV3;HLA-DRB5;TRAC;WAS;THY1;CD3E;CTSS;VAV1;FCGR3A;LCK;HLA-DPB1;HLA-DRA;FCGR1A;HLA-DQA2;HLA-DQB2;SKAP1;HLA-DQA1;SH2B2;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	immune response-regulating cell surface receptor signaling pathway (GO:0002768)	0.0000000	0.0000000	CD86;VAV3;HLA-DRB5;TRAC;WAS;THY1;CD3E;VAV1;FCGR3A;LCK;HLA-DPB1;HLA-DRA;FCGR1A;HLA-DQA2;HLA-DQB2;SKAP1;HLA-DQA1;SH2B2;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	antigen processing and presentation (GO:0019882)	0.0000000	0.0000000	CD74;HLA-DRB5;CTSS;HLA-DMA;HLA-DMB;HLA-DPB1;HLA-DRA;AP1S3;HLA-DOA;FCGR1A;HLA-DQA2;HLA-DQB2;AP1M2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	interferon-gamma-mediated signaling pathway (GO:0060333)	0.0000000	0.0000000	HLA-DRB5;HLA-DPB1;HLA-DRA;FCGR1A;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	response to interferon-gamma (GO:0034341)	0.0000000	0.0000000	CD86;HLA-DRB5;HLA-DPB1;HLA-DRA;FCGR1A;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	cellular response to interferon-gamma (GO:0071346)	0.0000000	0.0000000	HLA-DRB5;HLA-DPB1;HLA-DRA;FCGR1A;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	cytokine-mediated signaling pathway (GO:0019221)	0.0000000	0.0000000	CD74;HLA-DRB5;CXCL11;HLA-DPB1;HLA-DRA;FCGR1A;HLA-DQA2;HLA-DQB2;HLA-DQA1;SH2B2;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	cellular response to cytokine stimulus (GO:0071345)	0.0000000	0.0000000	CD86;CD74;HLA-DRB5;CXCL11;HLA-DPB1;HLA-DRA;FCGR1A;HLA-DQA2;HLA-DQB2;HLA-DQA1;SH2B2;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	immunoglobulin mediated immune response (GO:0016064)	0.0000000	0.0000000	CD74;HLA-DMA;FCGR1A;HLA-DRB1;HLA-DQB1
4	B cell mediated immunity (GO:0019724)	0.0000000	0.0000001	CD74;HLA-DMA;FCGR1A;HLA-DRB1;HLA-DQB1
4	regulation of lymphocyte proliferation (GO:0050670)	0.0000000	0.0000012	CD86;VAV3;CD74;HLA-DMB;HLA-DPB1;CD3E;HLA-DRB1;HLA-DPA1
4	regulation of mononuclear cell proliferation (GO:0032944)	0.0000000	0.0000012	CD86;VAV3;CD74;HLA-DMB;HLA-DPB1;CD3E;HLA-DRB1;HLA-DPA1
4	positive regulation of lymphocyte proliferation (GO:0050671)	0.0000001	0.0000015	CD86;VAV3;CD74;HLA-DMB;HLA-DPB1;CD3E;HLA-DPA1
4	regulation of leukocyte proliferation (GO:0070663)	0.0000001	0.0000015	CD86;VAV3;CD74;HLA-DMB;HLA-DPB1;CD3E;HLA-DRB1;HLA-DPA1
4	positive regulation of mononuclear cell proliferation (GO:0032946)	0.0000001	0.0000015	CD86;VAV3;CD74;HLA-DMB;HLA-DPB1;CD3E;HLA-DPA1
4	leukocyte mediated immunity (GO:0002443)	0.0000001	0.0000017	CD74;HLA-DMA;STXBP2;FCGR1A;HLA-DRB1;HLA-DQB1
4	positive regulation of leukocyte proliferation (GO:0070665)	0.0000001	0.0000017	CD86;VAV3;CD74;HLA-DMB;HLA-DPB1;CD3E;HLA-DPA1
4	regulation of antigen processing and presentation (GO:0002577)	0.0000002	0.0000053	CD74;TREM2;HLA-DOA;HLA-DQB2
4	adaptive immune response (GO:0002250)	0.0000003	0.0000074	CD74;HLA-DMA;FCGR1A;CTSS;HLA-DRB1;HLA-DQB1
4	regulation of T cell differentiation (GO:0045580)	0.0000005	0.0000105	CD86;CD74;HLA-DMA;LCK;RORC;HLA-DOA
4	lymphocyte mediated immunity (GO:0002449)	0.0000005	0.0000120	CD74;HLA-DMA;FCGR1A;HLA-DRB1;HLA-DQB1
4	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002460)	0.0000008	0.0000169	CD74;HLA-DMA;FCGR1A;HLA-DRB1;HLA-DQB1
4	cellular protein complex assembly (GO:0043623)	0.0000009	0.0000202	VAMP8;HLA-DMA;HLA-DMB;WAS;COBL;HLA-DRA;CD3E;HLA-DRB1
4	regulation of immune effector process (GO:0002697)	0.0000012	0.0000249	CD86;CD74;HLA-DMB;LCK;STXBP2;AP1S3;FCGR1A;AP1M2
4	leukocyte activation (GO:0045321)	0.0000016	0.0000329	CD86;TPD52;ANXA3;LCK;STXBP2;RORC;WAS;CD3E;VAV1
4	regulation of lymphocyte differentiation (GO:0045619)	0.0000019	0.0000389	CD86;CD74;HLA-DMA;LCK;RORC;HLA-DOA
4	regulation of T cell proliferation (GO:0042129)	0.0000020	0.0000399	CD86;HLA-DMB;HLA-DPB1;CD3E;HLA-DRB1;HLA-DPA1
4	positive regulation of T cell proliferation (GO:0042102)	0.0000050	0.0000968	CD86;HLA-DMB;HLA-DPB1;CD3E;HLA-DPA1
4	positive regulation of antigen processing and presentation (GO:0002579)	0.0000072	0.0001370	CD74;TREM2;HLA-DQB2
4	T cell activation (GO:0042110)	0.0000280	0.0005167	CD86;LCK;RORC;WAS;CD3E;VAV1
4	thymic T cell selection (GO:0045061)	0.0000282	0.0005167	CD74;HLA-DMA;CD3E
4	steroid hormone mediated signaling pathway (GO:0043401)	0.0000294	0.0005288	VDR;RORC;ESRRG;NR2F6
4	regulation of interleukin-4 production (GO:0032673)	0.0000328	0.0005789	CD86;CD3E;HLA-DRB1
4	lymphocyte activation (GO:0046649)	0.0000339	0.0005863	CD86;TPD52;LCK;RORC;WAS;CD3E;VAV1
4	positive regulation of T cell differentiation (GO:0045582)	0.0000382	0.0006485	CD86;CD74;HLA-DMA;LCK
4	regulation of leukocyte differentiation (GO:1902105)	0.0000389	0.0006496	CD86;CD74;HLA-DMA;LCK;RORC;HLA-DOA
4	positive regulation of immune effector process (GO:0002699)	0.0000491	0.0008048	CD86;CD74;HLA-DMB;STXBP2;FCGR1A
4	regulation of T cell receptor signaling pathway (GO:0050856)	0.0000563	0.0009070	LCK;PTPRJ;THY1
4	positive regulation of peptidyl-tyrosine phosphorylation (GO:0050731)	0.0000606	0.0009594	CD74;LCK;OSM;TREM2;CD3E
4	T cell selection (GO:0045058)	0.0000713	0.0011103	CD74;HLA-DMA;CD3E
4	positive regulation of lymphocyte differentiation (GO:0045621)	0.0000759	0.0011615	CD86;CD74;HLA-DMA;LCK
4	Fc receptor signaling pathway (GO:0038093)	0.0000854	0.0012867	CD86;VAV3;FCGR3A;LCK;WAS;FCGR1A;VAV1
4	regulation of defense response to virus by virus (GO:0050690)	0.0000887	0.0013153	LCK;AP1S3;AP1M2
4	regulation of interferon-gamma production (GO:0032649)	0.0000929	0.0013563	HLA-DPB1;CD3E;HLA-DRB1;HLA-DPA1
4	post-Golgi vesicle-mediated transport (GO:0006892)	0.0001542	0.0022160	VAMP8;SORT1;AP1S3;AP1M2
4	regulation of antigen receptor-mediated signaling pathway (GO:0050854)	0.0001569	0.0022203	LCK;PTPRJ;THY1
4	hormone-mediated signaling pathway (GO:0009755)	0.0001750	0.0024402	VDR;RORC;ESRRG;NR2F6
4	regulation of peptidyl-tyrosine phosphorylation (GO:0050730)	0.0002562	0.0034678	CD74;LCK;OSM;TREM2;CD3E
4	antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)	0.0002690	0.0035891	HLA-DMA;FCGR1A;CTSS;HLA-DQB1
4	negative regulation of immune system process (GO:0002683)	0.0003330	0.0043203	CD86;CD74;PTPRJ;THY1;HLA-DOA;HLA-DRB1
4	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis (GO:0002433)	0.0003560	0.0043292	VAV3;FCGR3A;WAS;FCGR1A;VAV1
4	Fc-gamma receptor signaling pathway involved in phagocytosis (GO:0038096)	0.0003560	0.0043292	VAV3;FCGR3A;WAS;FCGR1A;VAV1
4	Fc-gamma receptor signaling pathway (GO:0038094)	0.0003560	0.0043292	VAV3;FCGR3A;WAS;FCGR1A;VAV1
4	cell activation involved in immune response (GO:0002263)	0.0003569	0.0043292	CD86;ANXA3;STXBP2;RORC
4	leukocyte activation involved in immune response (GO:0002366)	0.0003569	0.0043292	CD86;ANXA3;STXBP2;RORC
4	Fc receptor mediated stimulatory signaling pathway (GO:0002431)	0.0003641	0.0043600	VAV3;FCGR3A;WAS;FCGR1A;VAV1
4	positive regulation of alpha-beta T cell activation (GO:0046635)	0.0004033	0.0045935	CD86;CD3E;HLA-DQB2
4	positive regulation of leukocyte differentiation (GO:1902107)	0.0004351	0.0048964	CD86;CD74;HLA-DMA;LCK
4	cellular response to steroid hormone stimulus (GO:0071383)	0.0005091	0.0055489	VDR;RORC;ESRRG;NR2F6
4	positive regulation of interferon-gamma production (GO:0032729)	0.0005109	0.0055489	HLA-DPB1;CD3E;HLA-DPA1
4	regulation of alpha-beta T cell activation (GO:0046634)	0.0008968	0.0088167	CD86;CD3E;HLA-DQB2
4	leukocyte differentiation (GO:0002521)	0.0009310	0.0089644	CD86;TPD52;LCK;RORC;TREM2
4	positive regulation of Rho GTPase activity (GO:0032321)	0.0010436	0.0098455	VAV3;THY1;GMIP;VAV1
4	neurotrophin TRK receptor signaling pathway (GO:0048011)	0.0013742	0.0125832	CD86;VAV3;LCK;SORT1;VAV1
4	neurotrophin signaling pathway (GO:0038179)	0.0014648	0.0130301	CD86;VAV3;LCK;SORT1;VAV1
4	regulation of defense response to virus (GO:0050688)	0.0016036	0.0141299	LCK;AP1S3;AP1M2
4	regulation of Rho GTPase activity (GO:0032319)	0.0018467	0.0156801	VAV3;THY1;GMIP;VAV1
4	myeloid leukocyte activation (GO:0002274)	0.0022011	0.0181929	CD86;ANXA3;STXBP2
4	regulation of vesicle-mediated transport (GO:0060627)	0.0022282	0.0182552	VAMP8;STXBP2;RAB27B;FCGR1A;PACSIN1
4	positive regulation of inflammatory response (GO:0050729)	0.0023501	0.0186261	OSM;FCGR1A;CTSS
4	intracellular receptor signaling pathway (GO:0030522)	0.0023532	0.0186261	VDR;RORC;ESRRG;NR2F6
4	transcription initiation from RNA polymerase II promoter (GO:0006367)	0.0023993	0.0188315	VDR;RORC;ESRRG;NR2F6
4	regulation of homeostatic process (GO:0032844)	0.0024914	0.0189770	CD74;CXCL11;LCK;THY1;HLA-DRB1
4	cellular response to lipid (GO:0071396)	0.0025259	0.0189770	CD86;VDR;RORC;ESRRG;NR2F6
4	cellular response to hormone stimulus (GO:0032870)	0.0025664	0.0190130	VDR;RORC;ESRRG;CTSS;SH2B2;NR2F6
4	positive regulation of calcium ion transport (GO:0051928)	0.0025853	0.0190130	CXCL11;LPAR3;THY1
4	positive regulation of cytokine production (GO:0001819)	0.0029666	0.0211512	CD86;CD74;HLA-DPB1;CD3E;HLA-DPA1
4	positive regulation of response to external stimulus (GO:0032103)	0.0031117	0.0220176	CD74;OSM;FCGR1A;CTSS
4	regulation of cytokine production (GO:0001817)	0.0031647	0.0220781	CD86;CD74;HLA-DPB1;CD3E;HLA-DRB1;HLA-DPA1
4	Golgi vesicle transport (GO:0048193)	0.0031675	0.0220781	VAMP8;SORT1;AP1S3;AP1M2
4	leukocyte chemotaxis (GO:0030595)	0.0033761	0.0233574	VAV3;CXCL11;VAV1
4	regulation of response to biotic stimulus (GO:0002831)	0.0040831	0.0276351	LCK;AP1S3;AP1M2
4	DNA-templated transcription, initiation (GO:0006352)	0.0042929	0.0288459	VDR;RORC;ESRRG;NR2F6
4	leukocyte migration (GO:0050900)	0.0047211	0.0312731	VAV3;CXCL11;LCK;VAV1
4	neuron development (GO:0048666)	0.0057514	0.0367931	THY1;PACSIN1;NR2F6
4	regulation of inflammatory response (GO:0050727)	0.0064449	0.0403993	OSM;FCGR1A;CTSS;HLA-DRB1
4	positive regulation of response to wounding (GO:1903036)	0.0070105	0.0427961	OSM;FCGR1A;CTSS
4	positive regulation of homeostatic process (GO:0032846)	0.0070105	0.0427961	CXCL11;THY1;HLA-DRB1
4	regulation of small GTPase mediated signal transduction (GO:0051056)	0.0072966	0.0442537	VAV3;GMIP;VAV1;SH2B2
4	cellular calcium ion homeostasis (GO:0006874)	0.0078006	0.0462134	CD52;LCK;VDR;LPAR3
4	inositol lipid-mediated signaling (GO:0048017)	0.0079339	0.0462134	CD86;LCK;VAV1
4	phosphatidylinositol-mediated signaling (GO:0048015)	0.0079339	0.0462134	CD86;LCK;VAV1
4	taxis (GO:0042330)	0.0080084	0.0462134	VAV3;CXCL11;PTPRJ;VAV1
4	chemotaxis (GO:0006935)	0.0080084	0.0462134	VAV3;CXCL11;PTPRJ;VAV1
4	cellular divalent inorganic cation homeostasis (GO:0072503)	0.0088762	0.0499418	CD52;LCK;VDR;LPAR3
4	positive regulation of defense response (GO:0031349)	0.0089888	0.0502727	CD86;OSM;FCGR1A;CTSS
4	calcium ion homeostasis (GO:0055074)	0.0092168	0.0509380	CD52;LCK;VDR;LPAR3
4	positive regulation of neuron projection development (GO:0010976)	0.0092719	0.0509411	COBL;LPAR3;PACSIN1
4	regulation of neuron projection development (GO:0010975)	0.0093323	0.0509728	COBL;LPAR3;THY1;PACSIN1
4	actin filament organization (GO:0007015)	0.0103570	0.0552768	WAS;COBL;PACSIN1
4	positive regulation of cytosolic calcium ion concentration (GO:0007204)	0.0107344	0.0569656	CD52;LCK;LPAR3
4	divalent inorganic cation homeostasis (GO:0072507)	0.0113092	0.0584816	CD52;LCK;VDR;LPAR3
4	cellular response to organic cyclic compound (GO:0071407)	0.0113092	0.0584816	VDR;RORC;ESRRG;NR2F6
4	cell chemotaxis (GO:0060326)	0.0113153	0.0584816	VAV3;CXCL11;VAV1
4	positive regulation of Ras GTPase activity (GO:0032320)	0.0114411	0.0584816	VAV3;THY1;GMIP;VAV1
4	Fc-epsilon receptor signaling pathway (GO:0038095)	0.0118425	0.0595954	CD86;VAV3;LCK;VAV1
4	regulation of ion homeostasis (GO:2000021)	0.0123234	0.0615510	CXCL11;LCK;THY1
4	fibroblast growth factor receptor signaling pathway (GO:0008543)	0.0129522	0.0643478	CD86;LCK;VAV1
4	regulation of endocytosis (GO:0030100)	0.0133815	0.0656701	VAMP8;FCGR1A;PACSIN1
4	coagulation (GO:0050817)	0.0135095	0.0656701	VAV3;LCK;WAS;VAV1;SH2B2
4	blood coagulation (GO:0007596)	0.0135095	0.0656701	VAV3;LCK;WAS;VAV1;SH2B2
4	hemostasis (GO:0007599)	0.0142004	0.0683667	VAV3;LCK;WAS;VAV1;SH2B2
4	regulation of calcium ion transport (GO:0051924)	0.0147180	0.0701355	CXCL11;LPAR3;THY1
4	positive regulation of cell adhesion (GO:0045785)	0.0147180	0.0701355	VAV3;PTPRJ;VAV1
4	lymphocyte differentiation (GO:0030098)	0.0149478	0.0705113	TPD52;LCK;RORC
4	cytosolic calcium ion homeostasis (GO:0051480)	0.0158875	0.0741947	CD52;LCK;LPAR3
4	endocytosis (GO:0006897)	0.0160316	0.0744951	ANXA3;SORT1;FCGR1A;PACSIN1
4	apoptotic signaling pathway (GO:0097190)	0.0166970	0.0772030	VAV3;SORT1;CD3E;VAV1
4	cellular response to fibroblast growth factor stimulus (GO:0044344)	0.0176108	0.0806298	CD86;LCK;VAV1
4	positive regulation of ion transport (GO:0043270)	0.0183801	0.0837416	CXCL11;LPAR3;THY1
4	response to fibroblast growth factor (GO:0071774)	0.0186407	0.0845164	CD86;LCK;VAV1
4	epidermal growth factor receptor signaling pathway (GO:0007173)	0.0202473	0.0889837	CD86;LCK;VAV1
4	regulation of response to wounding (GO:1903034)	0.0202840	0.0889837	OSM;FCGR1A;CTSS;HLA-DRB1
4	regulation of Ras GTPase activity (GO:0032318)	0.0206668	0.0900135	VAV3;THY1;GMIP;VAV1
4	positive regulation of cell projection organization (GO:0031346)	0.0207993	0.0900135	COBL;LPAR3;PACSIN1
4	ERBB signaling pathway (GO:0038127)	0.0210785	0.0907248	CD86;LCK;VAV1
4	positive regulation of cell development (GO:0010720)	0.0224450	0.0936107	VDR;COBL;LPAR3;PACSIN1
4	response to bacterium (GO:0009617)	0.0225051	0.0936107	ANXA3;FCGR1A;HLA-DRB1
4	cellular metal ion homeostasis (GO:0006875)	0.0230580	0.0936107	CD52;LCK;VDR;LPAR3
4	platelet activation (GO:0030168)	0.0236835	0.0936107	VAV3;LCK;VAV1
4	response to steroid hormone (GO:0048545)	0.0247424	0.0970983	VDR;RORC;ESRRG;NR2F6
4	inflammatory response (GO:0006954)	0.0262762	0.0992918	CXCL11;TNFAIP6;FCGR1A;HLA-DRB1
4	positive regulation of neuron differentiation (GO:0045666)	0.0274174	0.1016185	COBL;LPAR3;PACSIN1
4	cellular cation homeostasis (GO:0030003)	0.0292743	0.1031743	CD52;LCK;VDR;LPAR3
4	regulation of cell projection organization (GO:0031344)	0.0297530	0.1033058	COBL;LPAR3;THY1;PACSIN1
4	positive regulation of MAPK cascade (GO:0043410)	0.0307242	0.1062831	CD74;OSM;TREM2;LPAR3
4	cellular ion homeostasis (GO:0006873)	0.0324689	0.1069405	CD52;LCK;VDR;LPAR3
4	exocytosis (GO:0006887)	0.0328574	0.1076801	ANXA3;STXBP2;SYTL1
4	regulation of neuron differentiation (GO:0045664)	0.0332343	0.1081561	COBL;LPAR3;THY1;PACSIN1
4	secretion by cell (GO:0032940)	0.0358617	0.1127773	SLC44A4;ANXA3;STXBP2;SYTL1
4	regulation of lipid metabolic process (GO:0019216)	0.0372809	0.1150734	VAV3;VDR;RORC
4	metal ion homeostasis (GO:0055065)	0.0377711	0.1150734	CD52;LCK;VDR;LPAR3
4	regulation of metal ion transport (GO:0010959)	0.0392101	0.1173790	CXCL11;LPAR3;THY1
4	small GTPase mediated signal transduction (GO:0007264)	0.0426496	0.1233272	VAV3;RAB27B;GMIP;VAV1
4	humoral immune response (GO:0006959)	0.0444604	0.1242720	TREM2;HLA-DRB1;HLA-DQB1
4	cellular chemical homeostasis (GO:0055082)	0.0466112	0.1256537	CD52;LCK;VDR;LPAR3
4	regulation of MAP kinase activity (GO:0043405)	0.0487267	0.1299601	CD74;PTPRJ;LPAR3
4	response to other organism (GO:0051707)	0.0497948	0.1299601	CD86;ANXA3;FCGR1A;HLA-DRB1
4	cation homeostasis (GO:0055080)	0.0507729	0.1308255	CD52;LCK;VDR;LPAR3
4	dephosphorylation (GO:0016311)	0.0509330	0.1308255	LCK;DAPP1;PTPRJ
4	positive regulation of neurogenesis (GO:0050769)	0.0531875	0.1317695	COBL;LPAR3;PACSIN1
4	positive regulation of GTPase activity (GO:0043547)	0.0565161	0.1368331	VAV3;THY1;GMIP;VAV1
4	positive regulation of GTP catabolic process (GO:0033126)	0.0568645	0.1372389	VAV3;THY1;GMIP;VAV1
4	regulation of multi-organism process (GO:0043900)	0.0641671	0.1464700	LCK;AP1S3;AP1M2
4	positive regulation of nervous system development (GO:0051962)	0.0677026	0.1480452	COBL;LPAR3;PACSIN1
4	regulation of cell growth (GO:0001558)	0.0723772	0.1540413	SLC44A4;PTPRJ;LPAR3
4	defense response to other organism (GO:0098542)	0.0755728	0.1579082	CD86;ANXA3;FCGR1A
4	regulation of cell adhesion (GO:0030155)	0.0799303	0.1625177	VAV3;PTPRJ;VAV1
4	response to drug (GO:0042493)	0.0901266	0.1741466	CD86;VAV3;LCK
4	regulation of apoptotic signaling pathway (GO:2001233)	0.0912922	0.1741466	CD74;LCK;OSM
4	negative regulation of transport (GO:0051051)	0.0942338	0.1771670	CD74;OSM;PACSIN1
4	regulation of intracellular transport (GO:0032386)	0.1146023	0.2004467	CXCL11;STXBP2;THY1
4	regulation of protein serine/threonine kinase activity (GO:0071900)	0.1290376	0.2143678	CD74;PTPRJ;LPAR3
4	gene expression (GO:0010467)	0.1423936	0.2265684	VDR;RORC;ESRRG;NR2F6
4	negative regulation of phosphorus metabolic process (GO:0010563)	0.1582634	0.2415327	PTPRJ;THY1;GMIP
4	negative regulation of phosphate metabolic process (GO:0045936)	0.1582634	0.2415327	PTPRJ;THY1;GMIP
4	negative regulation of cellular component organization (GO:0051129)	0.1699050	0.2543389	OSM;THY1;PACSIN1
4	positive regulation of kinase activity (GO:0033674)	0.1743351	0.2592818	VAV3;CD74;LPAR3
4	Allograft rejection Homo sapiens hsa05330	0.0000000	0.0000000	CD86;HLA-DMA;HLA-DRB5;HLA-DMB;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Staphylococcus aureus infection Homo sapiens hsa05150	0.0000000	0.0000000	HLA-DRB5;FCGR3A;HLA-DMA;HLA-DMB;HLA-DPB1;HLA-DRA;HLA-DOA;FCGR1A;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Graft-versus-host disease Homo sapiens hsa05332	0.0000000	0.0000000	CD86;HLA-DMA;HLA-DRB5;HLA-DMB;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Type I diabetes mellitus Homo sapiens hsa04940	0.0000000	0.0000000	CD86;HLA-DMA;HLA-DRB5;HLA-DMB;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Asthma Homo sapiens hsa05310	0.0000000	0.0000000	HLA-DMA;HLA-DRB5;HLA-DMB;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Intestinal immune network for IgA production Homo sapiens hsa04672	0.0000000	0.0000000	CD86;HLA-DMA;HLA-DRB5;HLA-DMB;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Leishmaniasis Homo sapiens hsa05140	0.0000000	0.0000000	HLA-DRB5;FCGR3A;HLA-DMA;HLA-DMB;HLA-DPB1;HLA-DRA;HLA-DOA;FCGR1A;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Autoimmune thyroid disease Homo sapiens hsa05320	0.0000000	0.0000000	CD86;HLA-DMA;HLA-DRB5;HLA-DMB;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Antigen processing and presentation Homo sapiens hsa04612	0.0000000	0.0000000	CD74;HLA-DRB5;CTSS;HLA-DMA;HLA-DMB;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Tuberculosis Homo sapiens hsa05152	0.0000000	0.0000000	CD74;HLA-DRB5;VDR;CTSS;FCGR3A;HLA-DMA;HLA-DMB;HLA-DPB1;HLA-DRA;HLA-DOA;FCGR1A;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Viral myocarditis Homo sapiens hsa05416	0.0000000	0.0000000	CD86;HLA-DMA;HLA-DRB5;HLA-DMB;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Inflammatory bowel disease (IBD) Homo sapiens hsa05321	0.0000000	0.0000000	HLA-DMA;HLA-DRB5;HLA-DMB;RORC;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Systemic lupus erythematosus Homo sapiens hsa05322	0.0000000	0.0000000	CD86;HLA-DRB5;FCGR3A;HLA-DMA;HLA-DMB;HLA-DPB1;HLA-DRA;HLA-DOA;FCGR1A;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Phagosome Homo sapiens hsa04145	0.0000000	0.0000000	HLA-DRB5;CTSS;FCGR3A;HLA-DMA;HLA-DMB;HLA-DPB1;HLA-DRA;HLA-DOA;FCGR1A;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Rheumatoid arthritis Homo sapiens hsa05323	0.0000000	0.0000000	CD86;HLA-DMA;HLA-DRB5;HLA-DMB;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Cell adhesion molecules (CAMs) Homo sapiens hsa04514	0.0000000	0.0000000	CD86;HLA-DMA;HLA-DRB5;HLA-DMB;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Toxoplasmosis Homo sapiens hsa05145	0.0000000	0.0000000	HLA-DMA;HLA-DRB5;HLA-DMB;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Herpes simplex infection Homo sapiens hsa05168	0.0000000	0.0000000	CD74;HLA-DMA;HLA-DRB5;HLA-DMB;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	HTLV-I infection Homo sapiens hsa05166	0.0000000	0.0000000	HLA-DRB5;CD3E;HLA-DMA;HLA-DMB;LCK;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Influenza A Homo sapiens hsa05164	0.0000000	0.0000000	HLA-DMA;HLA-DRB5;HLA-DMB;HLA-DPB1;HLA-DRA;HLA-DOA;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Epstein-Barr virus infection Homo sapiens hsa05169	0.0000002	0.0000005	HLA-DRB5;HLA-DPB1;HLA-DRA;HLA-DQA2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Hematopoietic cell lineage Homo sapiens hsa04640	0.0000066	0.0000190	HLA-DRB5;HLA-DRA;CD3E;FCGR1A;HLA-DRB1
4	Fc gamma R-mediated phagocytosis Homo sapiens hsa04666	0.0000087	0.0000238	VAV3;FCGR3A;WAS;FCGR1A;VAV1
4	T cell receptor signaling pathway Homo sapiens hsa04660	0.0002690	0.0007061	VAV3;LCK;CD3E;VAV1
4	Lysosome Homo sapiens hsa04142	0.0005091	0.0012829	SORT1;AP1S3;CTSS;AP1M2
4	Osteoclast differentiation Homo sapiens hsa04380	0.0006641	0.0016091	FCGR3A;LCK;TREM2;FCGR1A
4	Natural killer cell mediated cytotoxicity Homo sapiens hsa04650	0.0007224	0.0016857	VAV3;FCGR3A;LCK;VAV1
4	B cell receptor signaling pathway Homo sapiens hsa04662	0.0013751	0.0030940	VAV3;DAPP1;VAV1
4	Chemokine signaling pathway Homo sapiens hsa04062	0.0023993	0.0052123	VAV3;CXCL11;WAS;VAV1
4	Leukocyte transendothelial migration Homo sapiens hsa04670	0.0053646	0.0111969	VAV3;THY1;VAV1
4	Regulation of actin cytoskeleton Homo sapiens hsa04810	0.0264561	0.0490215	VAV3;WAS;VAV1
4	Phosphorylation of CD3 and TCR zeta chains Homo sapiens R-HSA-202427	0.0000000	0.0000000	HLA-DRB5;TRAC;PTPRJ;CD3E;LCK;HLA-DPB1;HLA-DRA;HLA-DQA2;HLA-DQA1;HLA-DQB2;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Translocation of ZAP-70 to Immunological synapse Homo sapiens R-HSA-202430	0.0000000	0.0000000	HLA-DRB5;LCK;TRAC;HLA-DPB1;HLA-DRA;CD3E;HLA-DQA2;HLA-DQA1;HLA-DQB2;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Generation of second messenger molecules Homo sapiens R-HSA-202433	0.0000000	0.0000000	HLA-DRB5;TRAC;WAS;CD3E;LCK;HLA-DPB1;HLA-DRA;HLA-DQA2;HLA-DQA1;HLA-DQB2;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	PD-1 signaling Homo sapiens R-HSA-389948	0.0000000	0.0000000	HLA-DRB5;LCK;TRAC;HLA-DPB1;HLA-DRA;CD3E;HLA-DQA2;HLA-DQA1;HLA-DQB2;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	MHC class II antigen presentation Homo sapiens R-HSA-2132295	0.0000000	0.0000000	CD74;HLA-DRB5;CTSS;HLA-DMA;HLA-DMB;HLA-DPB1;HLA-DRA;AP1S3;HLA-DOA;HLA-DQA2;HLA-DQB2;AP1M2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Adaptive Immune System Homo sapiens R-HSA-1280218	0.0000000	0.0000000	CD86;TRAC;WAS;DAPP1;PTPRJ;TREM2;CD3E;CTSS;FCGR3A;HLA-DMA;HLA-DMB;AP1S3;HLA-DOA;FCGR1A;HLA-DQA2;AP1M2;HLA-DQA1;HLA-DPA1;CD74;HLA-DRB5;VAV1;LCK;HLA-DPB1;HLA-DRA;HLA-DQB2;HLA-DRB1;HLA-DQB1
4	Costimulation by the CD28 family Homo sapiens R-HSA-388841	0.0000000	0.0000000	CD86;HLA-DRB5;TRAC;CD3E;VAV1;LCK;HLA-DPB1;HLA-DRA;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	TCR signaling Homo sapiens R-HSA-202403	0.0000000	0.0000000	HLA-DRB5;TRAC;WAS;PTPRJ;CD3E;LCK;HLA-DPB1;HLA-DRA;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Immune System Homo sapiens R-HSA-168256	0.0000000	0.0000000	CD86;TRAC;WAS;DAPP1;PTPRJ;TREM2;CD3E;CTSS;FCGR3A;HLA-DMA;HLA-DMB;AP1S3;HLA-DOA;FCGR1A;HLA-DQA2;AP1M2;HLA-DQA1;HAVCR2;HLA-DPA1;VAV3;CD74;HLA-DRB5;OSM;VAV1;LCK;HLA-DPB1;HLA-DRA;HLA-DQB2;HLA-DRB1;HLA-DQB1
4	Downstream TCR signaling Homo sapiens R-HSA-202424	0.0000000	0.0000000	HLA-DRB5;LCK;TRAC;HLA-DPB1;HLA-DRA;CD3E;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Interferon gamma signaling Homo sapiens R-HSA-877300	0.0000000	0.0000000	HLA-DRB5;HLA-DPB1;HLA-DRA;FCGR1A;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Interferon Signaling Homo sapiens R-HSA-913531	0.0000000	0.0000000	HLA-DRB5;HLA-DPB1;HLA-DRA;FCGR1A;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HLA-DPA1;HLA-DQB1
4	Cytokine Signaling in Immune system Homo sapiens R-HSA-1280215	0.0000000	0.0000000	HLA-DRB5;OSM;VAV1;LCK;HLA-DPB1;HLA-DRA;FCGR1A;HLA-DQA2;HLA-DQB2;HLA-DQA1;HLA-DRB1;HAVCR2;HLA-DPA1;HLA-DQB1
4	Golgi Associated Vesicle Biogenesis Homo sapiens R-HSA-432722	0.0000006	0.0000058	TPD52;VAMP8;SORT1;AP1S3;AP1M2
4	trans-Golgi Network Vesicle Budding Homo sapiens R-HSA-199992	0.0000021	0.0000188	TPD52;VAMP8;SORT1;AP1S3;AP1M2
4	Clathrin derived vesicle budding Homo sapiens R-HSA-421837	0.0000021	0.0000188	TPD52;VAMP8;SORT1;AP1S3;AP1M2
4	CD28 dependent Vav1 pathway Homo sapiens R-HSA-389359	0.0000055	0.0000459	CD86;LCK;VAV1
4	Regulation of actin dynamics for phagocytic cup formation Homo sapiens R-HSA-2029482	0.0000107	0.0000838	VAV3;FCGR3A;WAS;FCGR1A;VAV1
4	Nuclear Receptor transcription pathway Homo sapiens R-HSA-383280	0.0000165	0.0001221	VDR;RORC;ESRRG;NR2F6
4	Fcgamma receptor (FCGR) dependent phagocytosis Homo sapiens R-HSA-2029480	0.0000300	0.0002115	VAV3;FCGR3A;WAS;FCGR1A;VAV1
4	Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters Homo sapiens R-HSA-164938	0.0000328	0.0002206	LCK;AP1S3;AP1M2
4	The role of Nef in HIV-1 replication and disease pathogenesis Homo sapiens R-HSA-164952	0.0000797	0.0005109	LCK;AP1S3;AP1M2
4	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Homo sapiens R-HSA-198933	0.0001078	0.0006610	FCGR3A;TRAC;TREM2;CD3E;FCGR1A
4	CD28 co-stimulation Homo sapiens R-HSA-389356	0.0001313	0.0007717	CD86;LCK;VAV1
4	Lysosome Vesicle Biogenesis Homo sapiens R-HSA-432720	0.0001569	0.0008849	VAMP8;AP1S3;AP1M2
4	GPVI-mediated activation cascade Homo sapiens R-HSA-114604	0.0005404	0.0028222	VAV3;LCK;VAV1
4	Innate Immune System Homo sapiens R-HSA-168249	0.0006323	0.0031841	CD86;VAV3;FCGR3A;LCK;WAS;TREM2;FCGR1A;CTSS;VAV1
4	Constitutive Signaling by Aberrant PI3K in Cancer Homo sapiens R-HSA-2219530	0.0008163	0.0039687	CD86;LCK;VAV1
4	PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Homo sapiens R-HSA-6811558	0.0019887	0.0084973	CD86;LCK;VAV1
4	PI3K/AKT Signaling in Cancer Homo sapiens R-HSA-2219528	0.0022011	0.0091280	CD86;LCK;VAV1
4	Negative regulation of the PI3K/AKT network Homo sapiens R-HSA-199418	0.0025053	0.0100930	CD86;LCK;VAV1
4	DAP12 signaling Homo sapiens R-HSA-2424491	0.0036830	0.0140352	CD86;VAV3;LCK;TREM2;VAV1
4	DAP12 interactions Homo sapiens R-HSA-2172127	0.0044119	0.0163703	CD86;VAV3;LCK;TREM2;VAV1
4	Signaling by the B Cell Receptor (BCR) Homo sapiens R-HSA-983705	0.0052560	0.0180355	CD86;LCK;DAPP1;VAV1
4	Rho GTPase cycle Homo sapiens R-HSA-194840	0.0058839	0.0180355	VAV3;GMIP;VAV1
4	PI-3K cascade:FGFR1 Homo sapiens R-HSA-5654689	0.0058839	0.0180355	CD86;LCK;VAV1
4	PI-3K cascade:FGFR3 Homo sapiens R-HSA-5654710	0.0058839	0.0180355	CD86;LCK;VAV1
4	PI3K events in ERBB4 signaling Homo sapiens R-HSA-1250342	0.0058839	0.0180355	CD86;LCK;VAV1
4	PIP3 activates AKT signaling Homo sapiens R-HSA-1257604	0.0058839	0.0180355	CD86;LCK;VAV1
4	PI-3K cascade:FGFR4 Homo sapiens R-HSA-5654720	0.0058839	0.0180355	CD86;LCK;VAV1
4	PI-3K cascade:FGFR2 Homo sapiens R-HSA-5654695	0.0058839	0.0180355	CD86;LCK;VAV1
4	Hemostasis Homo sapiens R-HSA-109582	0.0061011	0.0181071	VAV3;CD74;LCK;PCDH7;VAV1;SH2B2
4	GAB1 signalosome Homo sapiens R-HSA-180292	0.0062925	0.0181071	CD86;LCK;VAV1
4	PI3K/AKT activation Homo sapiens R-HSA-198203	0.0062925	0.0181071	CD86;LCK;VAV1
4	Host Interactions of HIV factors Homo sapiens R-HSA-162909	0.0068632	0.0193542	LCK;AP1S3;AP1M2
4	Platelet activation, signaling and aggregation Homo sapiens R-HSA-76002	0.0070049	0.0193665	VAV3;LCK;PCDH7;VAV1
4	Membrane Trafficking Homo sapiens R-HSA-199991	0.0084548	0.0224931	TPD52;VAMP8;SORT1;AP1S3;AP1M2
4	Role of LAT2/NTAL/LAB on calcium mobilization Homo sapiens R-HSA-2730905	0.0127406	0.0320790	CD86;LCK;VAV1
4	Vesicle-mediated transport Homo sapiens R-HSA-5653656	0.0159044	0.0373754	TPD52;VAMP8;SORT1;AP1S3;AP1M2
4	Signaling by SCF-KIT Homo sapiens R-HSA-1433557	0.0163622	0.0378207	CD86;LCK;VAV1;SH2B2
4	Downstream signaling events of B Cell Receptor (BCR) Homo sapiens R-HSA-1168372	0.0199744	0.0454256	CD86;LCK;VAV1
4	Signaling by Rho GTPases Homo sapiens R-HSA-194315	0.0243145	0.0527437	VAV3;WAS;GMIP;VAV1
4	HIV Infection Homo sapiens R-HSA-162906	0.0290609	0.0593853	LCK;AP1S3;AP1M2
4	Signaling by Interleukins Homo sapiens R-HSA-449147	0.0299940	0.0604166	LCK;OSM;VAV1;HAVCR2
4	Fc epsilon receptor (FCERI) signaling Homo sapiens R-HSA-2454202	0.0307242	0.0610157	CD86;VAV3;LCK;VAV1
4	Signalling by NGF Homo sapiens R-HSA-166520	0.0459887	0.0842130	CD86;VAV3;LCK;VAV1
4	Diseases of signal transduction Homo sapiens R-HSA-5663202	0.0554898	0.0978380	CD86;LCK;VAV1
4	Disease Homo sapiens R-HSA-1643685	0.0659492	0.1120343	CD86;LCK;AP1S3;VAV1;AP1M2
4	Downstream signaling of activated FGFR2 Homo sapiens R-HSA-5654696	0.0761115	0.1212962	CD86;LCK;VAV1
4	Downstream signaling of activated FGFR4 Homo sapiens R-HSA-5654716	0.0761115	0.1212962	CD86;LCK;VAV1
4	Downstream signaling of activated FGFR3 Homo sapiens R-HSA-5654708	0.0761115	0.1212962	CD86;LCK;VAV1
4	Signaling by ERBB4 Homo sapiens R-HSA-1236394	0.0766519	0.1212962	CD86;LCK;VAV1
4	Signaling by FGFR4 Homo sapiens R-HSA-5654743	0.0777378	0.1212962	CD86;LCK;VAV1
4	Downstream signaling of activated FGFR1 Homo sapiens R-HSA-5654687	0.0777378	0.1212962	CD86;LCK;VAV1
4	Signaling by FGFR3 Homo sapiens R-HSA-5654741	0.0782834	0.1212962	CD86;LCK;VAV1
4	Signaling by FGFR1 Homo sapiens R-HSA-5654736	0.0799303	0.1225018	CD86;LCK;VAV1
4	Downstream signal transduction Homo sapiens R-HSA-186763	0.0827088	0.1253972	CD86;LCK;VAV1
4	Infectious disease Homo sapiens R-HSA-5663205	0.0866687	0.1286346	LCK;AP1S3;AP1M2
4	Signaling by EGFR Homo sapiens R-HSA-177929	0.0907086	0.1332283	CD86;LCK;VAV1
4	Signaling by FGFR2 Homo sapiens R-HSA-5654738	0.0942338	0.1369791	CD86;LCK;VAV1
4	Signaling by PDGF Homo sapiens R-HSA-186797	0.0960177	0.1381479	CD86;LCK;VAV1
4	Signaling by FGFR Homo sapiens R-HSA-190236	0.0972147	0.1384573	CD86;LCK;VAV1
4	NGF signalling via TRKA from the plasma membrane Homo sapiens R-HSA-187037	0.1020641	0.1432378	CD86;LCK;VAV1
4	Generic Transcription Pathway Homo sapiens R-HSA-212436	0.2261138	0.2872256	VDR;RORC;ESRRG;NR2F6
4	Signal Transduction Homo sapiens R-HSA-162582	0.3176954	0.3671726	CD86;VAV3;CXCL11;LCK;WAS;LPAR3;GMIP;VAV1;SH2B2
4	GPCR downstream signaling Homo sapiens R-HSA-388396	0.3409682	0.3906412	VAV3;CXCL11;LPAR3;VAV1
4	Signaling by GPCR Homo sapiens R-HSA-372790	0.5487149	0.5817203	VAV3;CXCL11;LPAR3;VAV1
4	Gene Expression Homo sapiens R-HSA-74160	0.7318058	0.7477146	VDR;RORC;ESRRG;NR2F6
4	The Co-Stimulatory Signal During T-cell Activation Homo sapiens h ctla4Pathway	0.0000000	0.0000001	CD86;LCK;HLA-DRA;CD3E;HLA-DRB1
4	Lck and Fyn tyrosine kinases in initiation of TCR Activation Homo sapiens h tcraPathway	0.0000001	0.0000005	LCK;HLA-DRA;CD3E;HLA-DRB1
4	T Cell Receptor Signaling Pathway Homo sapiens h tcrPathway	0.0000006	0.0000038	LCK;HLA-DRA;CD3E;VAV1;HLA-DRB1
4	Role of MEF2D in T-cell Apoptosis Homo sapiens h mef2dPathway	0.0000019	0.0000085	LCK;HLA-DRA;CD3E;HLA-DRB1
4	Antigen Processing and Presentation Homo sapiens h mhcPathway	0.0000055	0.0000199	CD74;HLA-DRA;HLA-DRB1
4	Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor Homo sapiens h CSKPathway	0.0000083	0.0000248	LCK;HLA-DRA;CD3E;HLA-DRB1
5	DNA repair (GO:0006281)	0.0000000	0.0000006	RAD51AP1;POLQ;BLM;FEN1;RAD51;EXO1;XRCC2;RBBP8;DTL
5	DNA recombination (GO:0006310)	0.0000000	0.0000011	RAD51AP1;BLM;FEN1;RAD51;EXO1;XRCC2;RBBP8
5	double-strand break repair (GO:0006302)	0.0000000	0.0000011	RAD51AP1;BLM;FEN1;RAD51;XRCC2;RBBP8
5	double-strand break repair via homologous recombination (GO:0000724)	0.0000000	0.0000017	RAD51AP1;BLM;RAD51;XRCC2;RBBP8
5	recombinational repair (GO:0000725)	0.0000000	0.0000017	RAD51AP1;BLM;RAD51;XRCC2;RBBP8
5	DNA catabolic process, exonucleolytic (GO:0000738)	0.0000000	0.0000018	FEN1;BLM;EXO1;RBBP8
5	DNA replication (GO:0006260)	0.0000001	0.0000092	CDT1;POLQ;BLM;FEN1;RMI2;DTL
5	mitotic cell cycle (GO:0000278)	0.0000006	0.0000420	CDT1;CCNA1;ERCC6L;FEN1;XRCC2;E2F3;MYBL2
5	response to radiation (GO:0009314)	0.0000011	0.0000681	RAD51AP1;BLM;FEN1;RAD51;CDK5;XRCC2;DTL
5	DNA integrity checkpoint (GO:0031570)	0.0000044	0.0002419	CDT1;BLM;RBBP8;DTL
5	DNA catabolic process (GO:0006308)	0.0000087	0.0004340	BLM;FEN1;EXO1;RBBP8
5	G2 DNA damage checkpoint (GO:0031572)	0.0000114	0.0005170	BLM;RBBP8;DTL
5	response to ionizing radiation (GO:0010212)	0.0000208	0.0008736	RAD51AP1;BLM;RAD51;XRCC2
5	cellular response to ionizing radiation (GO:0071479)	0.0000267	0.0010408	RAD51AP1;BLM;RAD51
5	nuclear division (GO:0000280)	0.0000361	0.0013151	CCNA1;ERCC6L;RAD51;XRCC2;RBBP8
5	regulation of DNA recombination (GO:0000018)	0.0000413	0.0014099	RAD51AP1;BLM;RAD51
5	cell cycle checkpoint (GO:0000075)	0.0000466	0.0014959	CDT1;BLM;RBBP8;DTL
5	organelle fission (GO:0048285)	0.0000546	0.0015881	CCNA1;ERCC6L;RAD51;XRCC2;RBBP8
5	meiotic nuclear division (GO:0007126)	0.0000771	0.0020041	CCNA1;RAD51;XRCC2
5	DNA catabolic process, endonucleolytic (GO:0000737)	0.0000807	0.0020041	FEN1;EXO1;RBBP8
5	DNA damage checkpoint (GO:0000077)	0.0001338	0.0030448	BLM;RBBP8;DTL
5	nucleic acid phosphodiester bond hydrolysis (GO:0090305)	0.0002088	0.0045598	BLM;FEN1;EXO1;RBBP8
5	regulation of cell cycle process (GO:0010564)	0.0003413	0.0071665	CDT1;CCNA1;BLM;CDK5;GIPC1
5	regulation of DNA metabolic process (GO:0051052)	0.0003580	0.0072038	RAD51AP1;CDT1;BLM;RAD51
5	response to alkaloid (GO:0043279)	0.0003941	0.0072945	BLM;RAD51;CDK5
5	mitotic cell cycle phase transition (GO:0044772)	0.0004233	0.0072945	CDT1;CCNA1;RBBP8;MYBL2
5	cell cycle phase transition (GO:0044770)	0.0004409	0.0072945	CDT1;CCNA1;RBBP8;MYBL2
5	cellular response to radiation (GO:0071478)	0.0005709	0.0084252	RAD51AP1;BLM;RAD51
5	ATP catabolic process (GO:0006200)	0.0007893	0.0099017	POLQ;BLM;RAD51;XRCC2
5	purine ribonucleoside monophosphate catabolic process (GO:0009169)	0.0008352	0.0099017	POLQ;BLM;RAD51;XRCC2
5	ribonucleoside monophosphate catabolic process (GO:0009158)	0.0008352	0.0099017	POLQ;BLM;RAD51;XRCC2
5	purine nucleoside monophosphate catabolic process (GO:0009128)	0.0008446	0.0099017	POLQ;BLM;RAD51;XRCC2
5	nucleoside monophosphate catabolic process (GO:0009125)	0.0008637	0.0099017	POLQ;BLM;RAD51;XRCC2
5	cell cycle G1/S phase transition (GO:0044843)	0.0009842	0.0103341	CDT1;CCNA1;RBBP8
5	G1/S transition of mitotic cell cycle (GO:0000082)	0.0009842	0.0103341	CDT1;CCNA1;RBBP8
5	ATP metabolic process (GO:0046034)	0.0013376	0.0132790	POLQ;BLM;RAD51;XRCC2
5	purine ribonucleoside monophosphate metabolic process (GO:0009167)	0.0016933	0.0160861	POLQ;BLM;RAD51;XRCC2
5	purine nucleoside monophosphate metabolic process (GO:0009126)	0.0017088	0.0160861	POLQ;BLM;RAD51;XRCC2
5	ribonucleoside monophosphate metabolic process (GO:0009161)	0.0019190	0.0168993	POLQ;BLM;RAD51;XRCC2
5	nucleoside monophosphate metabolic process (GO:0009123)	0.0021104	0.0177270	POLQ;BLM;RAD51;XRCC2
5	regulation of binding (GO:0051098)	0.0027599	0.0206425	BLM;CDK5;ADD2
5	negative regulation of cellular component organization (GO:0051129)	0.0030788	0.0218312	CDK5;SEMA3A;CAPG;ADD2
5	cellular response to abiotic stimulus (GO:0071214)	0.0032895	0.0230263	RAD51AP1;BLM;RAD51
5	regulation of cell division (GO:0051302)	0.0033699	0.0232815	BLM;GIPC1;CABLES1
5	mitotic nuclear division (GO:0007067)	0.0036183	0.0240924	CCNA1;ERCC6L;RBBP8
5	regulation of actin cytoskeleton organization (GO:0032956)	0.0036183	0.0240924	CDK5;CAPG;ADD2
5	regulation of actin filament-based process (GO:0032970)	0.0043822	0.0288272	CDK5;CAPG;ADD2
5	response to light stimulus (GO:0009416)	0.0081708	0.0463734	FEN1;CDK5;DTL
5	regulation of cytoskeleton organization (GO:0051493)	0.0102520	0.0518675	CDK5;CAPG;ADD2
5	Homologous recombination Homo sapiens hsa03440	0.0000070	0.0002717	BLM;RAD51;XRCC2
5	Fanconi anemia pathway Homo sapiens hsa03460	0.0000438	0.0008533	BLM;RMI2;RAD51
5	Pathways in cancer Homo sapiens hsa05200	0.0016174	0.0210267	CCNA1;RAD51;SLC2A1;E2F3
5	HTLV-I infection Homo sapiens hsa05166	0.0044299	0.0345533	SLC2A1;E2F3;MYBL2
5	Homology Directed Repair Homo sapiens R-HSA-5693538	0.0000000	0.0000000	RAD51AP1;POLQ;CCNA1;BLM;FEN1;RMI2;RAD51;EXO1;XRCC2;RBBP8
5	DNA Double-Strand Break Repair Homo sapiens R-HSA-5693532	0.0000000	0.0000000	RAD51AP1;POLQ;CCNA1;BLM;FEN1;RMI2;RAD51;EXO1;XRCC2;RBBP8
5	Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Homo sapiens R-HSA-5693554	0.0000000	0.0000000	RAD51AP1;BLM;RMI2;RAD51;EXO1;XRCC2;RBBP8
5	Resolution of D-loop Structures through Holliday Junction Intermediates Homo sapiens R-HSA-5693568	0.0000000	0.0000000	RAD51AP1;BLM;RMI2;RAD51;EXO1;XRCC2;RBBP8
5	Resolution of D-Loop Structures Homo sapiens R-HSA-5693537	0.0000000	0.0000000	RAD51AP1;BLM;RMI2;RAD51;EXO1;XRCC2;RBBP8
5	DNA Repair Homo sapiens R-HSA-73894	0.0000000	0.0000000	RAD51AP1;POLQ;CCNA1;BLM;FEN1;RMI2;RAD51;EXO1;XRCC2;RBBP8;DTL
5	Homologous DNA Pairing and Strand Exchange Homo sapiens R-HSA-5693579	0.0000000	0.0000000	RAD51AP1;BLM;RMI2;RAD51;EXO1;XRCC2;RBBP8
5	HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) Homo sapiens R-HSA-5693567	0.0000000	0.0000000	RAD51AP1;CCNA1;BLM;RMI2;RAD51;EXO1;XRCC2;RBBP8
5	HDR through Homologous Recombination (HRR) Homo sapiens R-HSA-5685942	0.0000000	0.0000000	RAD51AP1;BLM;RMI2;RAD51;EXO1;XRCC2;RBBP8
5	Presynaptic phase of homologous DNA pairing and strand exchange Homo sapiens R-HSA-5693616	0.0000000	0.0000000	BLM;RMI2;RAD51;EXO1;XRCC2;RBBP8
5	Cell Cycle Homo sapiens R-HSA-1640170	0.0000000	0.0000000	CDT1;CCNA1;BLM;ERCC6L;FEN1;RMI2;RAD51;EXO1;RBBP8;E2F3;MYBL2
5	HDR through Single Strand Annealing (SSA) Homo sapiens R-HSA-5685938	0.0000000	0.0000000	BLM;RMI2;RAD51;EXO1;RBBP8
5	Regulation of TP53 Activity through Phosphorylation Homo sapiens R-HSA-6804756	0.0000000	0.0000000	CCNA1;BLM;RMI2;CDK5;EXO1;RBBP8
5	Regulation of TP53 Activity Homo sapiens R-HSA-5633007	0.0000000	0.0000004	CCNA1;BLM;RMI2;CDK5;EXO1;RBBP8
5	Processing of DNA double-strand break ends Homo sapiens R-HSA-5693607	0.0000001	0.0000006	CCNA1;BLM;RMI2;EXO1;RBBP8
5	HDR through MMEJ (alt-NHEJ) Homo sapiens R-HSA-5685939	0.0000002	0.0000022	POLQ;FEN1;RBBP8
5	G2/M DNA damage checkpoint Homo sapiens R-HSA-69473	0.0000030	0.0000266	BLM;RMI2;EXO1;RBBP8
5	Cell Cycle Checkpoints Homo sapiens R-HSA-69620	0.0000033	0.0000279	CCNA1;BLM;RMI2;EXO1;RBBP8
5	Transcriptional Regulation by TP53 Homo sapiens R-HSA-3700989	0.0000046	0.0000362	CCNA1;BLM;RMI2;CDK5;EXO1;RBBP8
5	DNA Replication Homo sapiens R-HSA-69306	0.0000098	0.0000741	CDT1;CCNA1;FEN1;E2F3
5	Cell Cycle, Mitotic Homo sapiens R-HSA-69278	0.0000229	0.0001569	CDT1;CCNA1;ERCC6L;FEN1;E2F3;MYBL2
5	Mitotic G1-G1/S phases Homo sapiens R-HSA-453279	0.0000272	0.0001787	CDT1;CCNA1;E2F3;MYBL2
5	G2/M Checkpoints Homo sapiens R-HSA-69481	0.0000400	0.0002514	BLM;RMI2;EXO1;RBBP8
5	Meiotic recombination Homo sapiens R-HSA-912446	0.0000463	0.0002796	BLM;RAD51;RBBP8
5	Regulation of DNA replication Homo sapiens R-HSA-69304	0.0001238	0.0007188	CDT1;CCNA1;E2F3
5	Meiosis Homo sapiens R-HSA-1500620	0.0001795	0.0009679	BLM;RAD51;RBBP8
5	Synthesis of DNA Homo sapiens R-HSA-69239	0.0002652	0.0012916	CDT1;CCNA1;FEN1
5	Generic Transcription Pathway Homo sapiens R-HSA-212436	0.0005039	0.0023056	CCNA1;BLM;RMI2;CDK5;EXO1;RBBP8
5	S Phase Homo sapiens R-HSA-69242	0.0005449	0.0024200	CDT1;CCNA1;FEN1
5	Mitotic G2-G2/M phases Homo sapiens R-HSA-453274	0.0014764	0.0061928	CCNA1;E2F3;MYBL2
5	Gene Expression Homo sapiens R-HSA-74160	0.0039060	0.0141214	CCNA1;BLM;RMI2;CDK5;EXO1;RBBP8;LSM4
5	Signal Transduction Homo sapiens R-HSA-162582	0.6377346	0.6506616	ERCC6L;CDK5;E2F3
6	regulation of dephosphorylation (GO:0035303)	0.0000171	0.0052806	SH3RF2;CDCA2;LMTK3;ARFGEF3
6	negative regulation of phosphatase activity (GO:0010923)	0.0000716	0.0091741	SH3RF2;LMTK3;ARFGEF3
6	negative regulation of dephosphorylation (GO:0035305)	0.0000894	0.0091741	SH3RF2;LMTK3;ARFGEF3
6	mitotic nuclear division (GO:0007067)	0.0002098	0.0161549	ANLN;CDCA2;MISP;CIT
6	regulation of phosphatase activity (GO:0010921)	0.0002730	0.0168162	SH3RF2;LMTK3;ARFGEF3
6	nuclear division (GO:0000280)	0.0004773	0.0244563	ANLN;CDCA2;MISP;CIT
6	organelle fission (GO:0048285)	0.0006611	0.0254541	ANLN;CDCA2;MISP;CIT
6	neuron projection guidance (GO:0097485)	0.0010399	0.0291175	UNC5A;UNC5B;B3GNT2;NTN1
6	axon guidance (GO:0007411)	0.0010399	0.0291175	UNC5A;UNC5B;B3GNT2;NTN1
6	negative regulation of phosphorus metabolic process (GO:0010563)	0.0023439	0.0487768	SH3RF2;PPP1R1B;LMTK3;ARFGEF3
6	negative regulation of phosphate metabolic process (GO:0045936)	0.0023439	0.0487768	SH3RF2;PPP1R1B;LMTK3;ARFGEF3
6	negative regulation of hydrolase activity (GO:0051346)	0.0094747	0.1167282	SH3RF2;LMTK3;ARFGEF3
6	regulation of cell projection organization (GO:0031344)	0.0123954	0.1240428	PPP1R16B;NTN1;CIT
6	positive regulation of GTPase activity (GO:0043547)	0.0215850	0.1266520	RABIF;IQGAP3;ARFGEF3
6	positive regulation of GTP catabolic process (GO:0033126)	0.0217021	0.1266520	RABIF;IQGAP3;ARFGEF3
6	Axon guidance Homo sapiens hsa04360	0.0005192	0.0067501	UNC5A;UNC5B;NTN1
6	Netrin mediated repulsion signals Homo sapiens R-HSA-418886	0.0000002	0.0000097	UNC5A;UNC5B;NTN1
6	Netrin-1 signaling Homo sapiens R-HSA-373752	0.0000192	0.0004507	UNC5A;UNC5B;NTN1
6	Axon guidance Homo sapiens R-HSA-422475	0.0256384	0.0547730	UNC5A;UNC5B;NTN1
6	Developmental Biology Homo sapiens R-HSA-1266738	0.0732483	0.1121911	UNC5A;UNC5B;NTN1
6	Signal Transduction Homo sapiens R-HSA-162582	0.3718796	0.4263010	PPP1R1B;IQGAP3;CIT;PPP1CA
6	Metabolism Homo sapiens R-HSA-1430728	0.4314027	0.4715332	B3GNT3;B3GNT2;PPP1CA
7	cellular response to type I interferon (GO:0071357)	0.0000000	0.0000002	IFI27;MX2;ISG15;IFIT1;IFIT3;OASL
7	type I interferon signaling pathway (GO:0060337)	0.0000000	0.0000002	IFI27;MX2;ISG15;IFIT1;IFIT3;OASL
7	response to type I interferon (GO:0034340)	0.0000000	0.0000002	IFI27;MX2;ISG15;IFIT1;IFIT3;OASL
7	defense response to virus (GO:0051607)	0.0000000	0.0000005	RSAD2;MX2;ISG15;IFIT1;IFI44L;IFIT3;OASL
7	negative regulation of viral genome replication (GO:0045071)	0.0000000	0.0000006	RSAD2;SLPI;ISG15;IFIT1;OASL
7	regulation of viral genome replication (GO:0045069)	0.0000000	0.0000032	RSAD2;SLPI;ISG15;IFIT1;OASL
7	actin filament-based movement (GO:0030048)	0.0000001	0.0000039	TPM3;TNNT1;TNNC1;TNNI1;MYH14
7	negative regulation of viral process (GO:0048525)	0.0000002	0.0000092	RSAD2;SLPI;ISG15;IFIT1;OASL
7	response to virus (GO:0009615)	0.0000002	0.0000092	RSAD2;MX2;ISG15;IFIT1;IFI44L;IFIT3;OASL
7	muscle filament sliding (GO:0030049)	0.0000005	0.0000210	TPM3;TNNT1;TNNC1;TNNI1
7	actin-myosin filament sliding (GO:0033275)	0.0000005	0.0000210	TPM3;TNNT1;TNNC1;TNNI1
7	actin-mediated cell contraction (GO:0070252)	0.0000011	0.0000397	TPM3;TNNT1;TNNC1;TNNI1
7	defense response to other organism (GO:0098542)	0.0000011	0.0000397	RSAD2;MX2;ISG15;IFIT1;IFI44L;IFIT3;OASL
7	negative regulation of multi-organism process (GO:0043901)	0.0000029	0.0000963	RSAD2;SLPI;ISG15;IFIT1;OASL
7	regulation of viral process (GO:0050792)	0.0000055	0.0001714	RSAD2;SLPI;ISG15;IFIT1;OASL
7	skeletal muscle contraction (GO:0003009)	0.0000058	0.0001714	TNNT1;TNNC1;MYH14
7	response to other organism (GO:0051707)	0.0000105	0.0002781	RSAD2;MX2;ISG15;IFIT1;IFI44L;IFIT3;OASL
7	regulation of symbiosis, encompassing mutualism through parasitism (GO:0043903)	0.0000107	0.0002781	RSAD2;SLPI;ISG15;IFIT1;OASL
7	cytokine-mediated signaling pathway (GO:0019221)	0.0000215	0.0005302	IFI27;MX2;ISG15;IFIT1;IFIT3;OASL
7	regulation of DNA replication (GO:0006275)	0.0000466	0.0010920	PIF1;PCNA;DSCC1;ESCO2
7	cellular response to cytokine stimulus (GO:0071345)	0.0001269	0.0028345	IFI27;MX2;ISG15;IFIT1;IFIT3;OASL
7	actin filament-based process (GO:0030029)	0.0001498	0.0031943	TPM3;TNNT1;TNNC1;TNNI1;MYH14
7	regulation of multi-organism process (GO:0043900)	0.0001569	0.0031991	RSAD2;SLPI;ISG15;IFIT1;OASL
7	striated muscle contraction (GO:0006941)	0.0002371	0.0046324	TNNT1;TNNC1;MYH14
7	muscle contraction (GO:0006936)	0.0003232	0.0060630	TPM3;TNNT1;TNNC1;MYH14
7	muscle system process (GO:0003012)	0.0006743	0.0117128	TPM3;TNNT1;TNNC1;MYH14
7	regulation of muscle contraction (GO:0006937)	0.0009488	0.0153451	TNNT1;TNNC1;TNNI1
7	regulation of DNA metabolic process (GO:0051052)	0.0010220	0.0159772	PIF1;PCNA;DSCC1;ESCO2
7	regulation of muscle system process (GO:0090257)	0.0018574	0.0261780	TNNT1;TNNC1;TNNI1
7	regulation of endopeptidase activity (GO:0052548)	0.0029425	0.0383344	EGLN3;IFI27;SLPI;CD109
7	regulation of peptidase activity (GO:0052547)	0.0035147	0.0422666	EGLN3;IFI27;SLPI;CD109
7	DNA replication (GO:0006260)	0.0038312	0.0449210	CDC45;DSCC1;CDC25C
7	mitotic cell cycle (GO:0000278)	0.0047118	0.0526156	PCNA;CDC45;ESCO2;CDC25C
7	mitotic cell cycle phase transition (GO:0044772)	0.0114555	0.1067763	PCNA;CDC45;CDC25C
7	cell cycle phase transition (GO:0044770)	0.0117924	0.1067763	PCNA;CDC45;CDC25C
7	negative regulation of hydrolase activity (GO:0051346)	0.0219398	0.1182732	SLPI;CD109;IFIT1
7	regulation of system process (GO:0044057)	0.0247776	0.1231483	TNNT1;TNNC1;TNNI1
7	regulation of intracellular transport (GO:0032386)	0.0289205	0.1291782	MX2;TNNC1;TACC3
7	DNA repair (GO:0006281)	0.0306365	0.1330418	PIF1;PCNA;ESCO2
7	monocarboxylic acid metabolic process (GO:0032787)	0.0457838	0.1491153	LDHA;EGLN3;PKM
7	Cell cycle Homo sapiens hsa04110	0.0012096	0.0430737	PCNA;CDC45;CDC25C
7	Metabolic pathways Homo sapiens hsa01100	0.3529239	0.3660628	LDHA;PKM;ALPL
7	Interferon alpha/beta signaling Homo sapiens R-HSA-909733	0.0000000	0.0000000	RSAD2;IFI27;MX2;ISG15;IFIT1;IFIT3;OASL
7	Interferon Signaling Homo sapiens R-HSA-913531	0.0000000	0.0000020	RSAD2;IFI27;MX2;ISG15;IFIT1;IFIT3;OASL
7	Striated Muscle Contraction Homo sapiens R-HSA-390522	0.0000003	0.0000123	TPM3;TNNT1;TNNC1;TNNI1
7	Termination of translesion DNA synthesis Homo sapiens R-HSA-5656169	0.0000177	0.0005254	PCNA;USP43;ISG15
7	Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template Homo sapiens R-HSA-110313	0.0000335	0.0007979	PCNA;USP43;ISG15
7	DNA Damage Bypass Homo sapiens R-HSA-73893	0.0000648	0.0011729	PCNA;USP43;ISG15
7	Cytokine Signaling in Immune system Homo sapiens R-HSA-1280215	0.0000690	0.0011729	RSAD2;IFI27;MX2;ISG15;IFIT1;IFIT3;OASL
7	ISG15 antiviral mechanism Homo sapiens R-HSA-1169408	0.0002471	0.0032669	MX2;ISG15;IFIT1
7	Antiviral mechanism by IFN-stimulated genes Homo sapiens R-HSA-1169410	0.0002471	0.0032669	MX2;ISG15;IFIT1
7	Muscle contraction Homo sapiens R-HSA-397014	0.0003295	0.0039214	TPM3;TNNT1;TNNC1;TNNI1
7	S Phase Homo sapiens R-HSA-69242	0.0012096	0.0110728	PCNA;CDC45;ESCO2
7	Cell Cycle, Mitotic Homo sapiens R-HSA-69278	0.0075330	0.0471801	PCNA;CDC45;ESCO2;CDC25C
7	DNA Repair Homo sapiens R-HSA-73894	0.0123666	0.0668920	PCNA;USP43;ISG15
7	Immune System Homo sapiens R-HSA-168256	0.0137998	0.0684240	RSAD2;IFI27;MX2;ISG15;IFIT1;IFIT3;OASL
7	Cell Cycle Homo sapiens R-HSA-1640170	0.0150261	0.0710097	PCNA;CDC45;ESCO2;CDC25C
8	cell junction organization (GO:0034330)	0.0000000	0.0000000	CDH6;DSP;LAMA5;CDH2;JUP;LAMB3;ITGB4;CDH1;PERP;LAMC2;PKP3
8	cell junction assembly (GO:0034329)	0.0000000	0.0000000	CDH6;LAMA5;CDH2;JUP;LAMB3;ITGB4;CDH1;LAMC2;PKP3
8	single organism cell adhesion (GO:0098602)	0.0000000	0.0000000	DSP;LAMA5;CDH2;JUP;CDH1;PERP;ITGB7;CTNNA2;PKP3;DSC2
8	single organismal cell-cell adhesion (GO:0016337)	0.0000000	0.0000001	DSP;CDH2;JUP;CDH1;PERP;ITGB7;CTNNA2;PKP3;DSC2
8	bundle of His cell to Purkinje myocyte communication (GO:0086069)	0.0000000	0.0000001	DSP;JUP;DSG2;DSC2
8	desmosome organization (GO:0002934)	0.0000000	0.0000001	DSP;JUP;PERP;PKP3
8	cell-cell junction organization (GO:0045216)	0.0000000	0.0000001	CDH6;DSP;LAMA5;CDH2;JUP;CDH1;PERP;PKP3
8	adherens junction organization (GO:0034332)	0.0000000	0.0000005	CDH6;DSP;LAMA5;CDH2;JUP;CDH1
8	homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)	0.0000000	0.0000011	CDH6;CDH2;CDH1;DSG2;PCDH19;DSC2;DSC3
8	extracellular matrix organization (GO:0030198)	0.0000000	0.0000024	LAMA5;LAMB3;ITGB4;CDH1;ITGA3;HAS2;LAMC2;ITGB7;AGRN
8	extracellular structure organization (GO:0043062)	0.0000000	0.0000024	LAMA5;LAMB3;ITGB4;CDH1;ITGA3;HAS2;LAMC2;ITGB7;AGRN
8	ventricular cardiac muscle cell action potential (GO:0086005)	0.0000001	0.0000033	DSP;JUP;DSG2;DSC2
8	regulation of heart rate by cardiac conduction (GO:0086091)	0.0000001	0.0000047	DSP;JUP;DSG2;DSC2
8	cell-cell adhesion via plasma-membrane adhesion molecules (GO:0098742)	0.0000001	0.0000051	CDH6;CDH2;CDH1;DSG2;PCDH19;DSC2;DSC3
8	cell-cell adhesion (GO:0098609)	0.0000001	0.0000051	CDH6;CDH2;CDH1;DSG2;PCDH19;DSC2;DSC3
8	cell communication involved in cardiac conduction (GO:0086065)	0.0000001	0.0000056	DSP;JUP;DSG2;DSC2
8	cardiac conduction (GO:0061337)	0.0000002	0.0000089	DSP;JUP;DSG2;DSC2
8	cardiac muscle cell action potential involved in contraction (GO:0086002)	0.0000003	0.0000133	DSP;JUP;DSG2;DSC2
8	cardiac muscle cell action potential (GO:0086001)	0.0000004	0.0000146	DSP;JUP;DSG2;DSC2
8	integrin-mediated signaling pathway (GO:0007229)	0.0000008	0.0000266	LAMA5;TEC;ITGB4;ITGA3;ITGB7
8	cell-substrate junction assembly (GO:0007044)	0.0000015	0.0000479	LAMA5;LAMB3;ITGB4;LAMC2
8	multicellular organismal signaling (GO:0035637)	0.0000016	0.0000505	DSP;JUP;DSG2;DSC2
8	hemidesmosome assembly (GO:0031581)	0.0000017	0.0000522	LAMB3;ITGB4;LAMC2
8	cell morphogenesis (GO:0000902)	0.0000035	0.0001006	LAMA5;JUP;CDH1;HAS2;SHROOM3;ITGB7
8	establishment of protein localization to plasma membrane (GO:0090002)	0.0000068	0.0001885	LAMA5;JUP;CDH1;PKP3
8	cell-substrate adhesion (GO:0031589)	0.0000096	0.0002544	LAMA5;BCAM;ITGB4;ITGA3;ITGB7
8	action potential (GO:0001508)	0.0000119	0.0003053	DSP;JUP;DSG2;DSC2
8	regulation of heart rate (GO:0002027)	0.0000141	0.0003488	DSP;JUP;DSG2;DSC2
8	cellular component morphogenesis (GO:0032989)	0.0000268	0.0006387	LAMA5;JUP;CDH1;HAS2;SHROOM3;ITGB7;CTNNA2
8	odontogenesis (GO:0042476)	0.0000440	0.0010146	LAMA5;ITGB4;PERP;AQP5
8	skin development (GO:0043588)	0.0000500	0.0011145	JUP;ITGB4;ITGA3
8	cell-matrix adhesion (GO:0007160)	0.0000517	0.0011162	BCAM;ITGB4;ITGA3;ITGB7
8	receptor clustering (GO:0043113)	0.0000545	0.0011405	DOK7;ITGB7;AGRN
8	water homeostasis (GO:0030104)	0.0000642	0.0013042	CDH1;AQP9;SFN
8	cellular component disassembly (GO:0022411)	0.0000738	0.0014566	DSP;LAMA5;LAMB3;CDH1;LAMC2;DSG2
8	water transport (GO:0006833)	0.0000807	0.0015498	AQP9;HAS2;AQP5
8	extracellular matrix disassembly (GO:0022617)	0.0000922	0.0017215	LAMA5;LAMB3;CDH1;LAMC2
8	epidermis development (GO:0008544)	0.0001051	0.0019117	DSP;LAMA5;LAMB3;LAMC2
8	fluid transport (GO:0042044)	0.0001142	0.0020228	AQP9;HAS2;AQP5
8	cellular component disassembly involved in execution phase of apoptosis (GO:0006921)	0.0001744	0.0030134	DSP;CDH1;DSG2
8	regulation of heart contraction (GO:0008016)	0.0001905	0.0032103	DSP;JUP;DSG2;DSC2
8	cell morphogenesis involved in differentiation (GO:0000904)	0.0002296	0.0037779	LAMA5;CDH1;HAS2;ITGB7
8	odontogenesis of dentin-containing tooth (GO:0042475)	0.0003814	0.0059892	LAMA5;ITGB4;PERP
8	cell-cell junction assembly (GO:0007043)	0.0005264	0.0080837	JUP;CDH1;PKP3
8	regulation of cell adhesion (GO:0030155)	0.0005925	0.0089010	LAMA5;DMTN;CDH1;ITGA3;HAS2
8	regulation of blood circulation (GO:1903522)	0.0007921	0.0111698	DSP;JUP;DSG2;DSC2
8	regulation of cell-cell adhesion (GO:0022407)	0.0009417	0.0123396	DMTN;CDH1;HAS2
8	positive regulation of nucleocytoplasmic transport (GO:0046824)	0.0009417	0.0123396	JUP;CDH1;SFN
8	regulation of Wnt signaling pathway (GO:0030111)	0.0009465	0.0123396	CDH2;JUP;CDH1;ITGA3
8	regulation of intracellular protein transport (GO:0033157)	0.0010311	0.0131943	DMTN;JUP;CDH1;SFN
8	regulation of intracellular transport (GO:0032386)	0.0012096	0.0147433	DMTN;JUP;CDH1;CD300A;SFN
8	establishment of protein localization to membrane (GO:0090150)	0.0012162	0.0147433	LAMA5;JUP;CDH1;PKP3
8	organ morphogenesis (GO:0009887)	0.0013664	0.0160324	LAMA5;ITGB4;PERP;AQP5;CTNNA2
8	epithelial cell development (GO:0002064)	0.0013689	0.0160324	CDH1;SHROOM3;SFN
8	synapse organization (GO:0050808)	0.0015212	0.0169535	CDH1;DOK7;AGRN
8	epithelium development (GO:0060429)	0.0018304	0.0197628	DSP;LAMA5;LAMB3;LAMC2
8	regulation of establishment of protein localization (GO:0070201)	0.0020056	0.0209979	DMTN;JUP;CDH1;ITGA3;SFN
8	regulation of membrane potential (GO:0042391)	0.0021043	0.0213835	DSP;JUP;DSG2;DSC2
8	negative regulation of Wnt signaling pathway (GO:0030178)	0.0021853	0.0217819	CDH2;JUP;CDH1
8	protein localization to membrane (GO:0072657)	0.0024054	0.0227688	CDH1;DOK7;ITGB7;AGRN
8	positive regulation of intracellular protein transport (GO:0090316)	0.0024408	0.0227918	JUP;CDH1;SFN
8	cellular response to organic cyclic compound (GO:0071407)	0.0029109	0.0261225	DMTN;JUP;CDH1;AQP9
8	regulation of canonical Wnt signaling pathway (GO:0060828)	0.0037131	0.0324780	CDH2;JUP;CDH1
8	regulation of protein targeting (GO:1903533)	0.0048298	0.0412024	DMTN;JUP;CDH1
8	positive regulation of cell adhesion (GO:0045785)	0.0051582	0.0434674	DMTN;ITGA3;HAS2
8	detection of external stimulus (GO:0009581)	0.0054998	0.0457877	JUP;LRP2;AGRN
8	regulation of nucleocytoplasmic transport (GO:0046822)	0.0057648	0.0468642	JUP;CDH1;SFN
8	detection of abiotic stimulus (GO:0009582)	0.0057648	0.0468642	JUP;LRP2;AGRN
8	regulation of peptidyl-tyrosine phosphorylation (GO:0050730)	0.0068014	0.0545519	DMTN;CD300A;DOK7
8	regulation of system process (GO:0044057)	0.0068683	0.0545519	DSP;JUP;DSG2;DSC2
8	regulation of protein transport (GO:0051223)	0.0073954	0.0580710	DMTN;JUP;CDH1;SFN
8	regulation of cysteine-type endopeptidase activity (GO:2000116)	0.0076207	0.0585641	CDH1;PERP;SFN
8	cellular response to organonitrogen compound (GO:0071417)	0.0097709	0.0718269	DMTN;JUP;CDH1;AQP9
8	positive regulation of intracellular transport (GO:0032388)	0.0099164	0.0721285	JUP;CDH1;SFN
8	positive regulation of protein transport (GO:0051222)	0.0117387	0.0819337	JUP;CDH1;SFN
8	cellular response to nitrogen compound (GO:1901699)	0.0121250	0.0829544	DMTN;JUP;CDH1;AQP9
8	response to metal ion (GO:0010038)	0.0152859	0.0945654	DMTN;CDH1;AQP9
8	negative regulation of protein phosphorylation (GO:0001933)	0.0160931	0.0945654	DMTN;CD300A;SFN
8	single-organism cellular localization (GO:1902580)	0.0183472	0.0967782	CDH1;DOK7;ITGB7;AGRN
8	positive regulation of cell migration (GO:0030335)	0.0195600	0.0999759	DMTN;ITGA3;HAS2
8	positive regulation of cell motility (GO:2000147)	0.0208638	0.0999759	DMTN;ITGA3;HAS2
8	positive regulation of cellular component movement (GO:0051272)	0.0226093	0.0999759	DMTN;ITGA3;HAS2
8	positive regulation of locomotion (GO:0040017)	0.0242262	0.0999759	DMTN;ITGA3;HAS2
8	negative regulation of phosphorylation (GO:0042326)	0.0287633	0.1062859	DMTN;CD300A;SFN
8	regulation of endopeptidase activity (GO:0052548)	0.0357230	0.1199462	CDH1;PERP;SFN
8	tissue morphogenesis (GO:0048729)	0.0367457	0.1209107	DSP;LAMA5;JUP
8	response to inorganic substance (GO:0010035)	0.0399042	0.1259078	DMTN;CDH1;AQP9
8	regulation of peptidase activity (GO:0052547)	0.0404438	0.1264554	CDH1;PERP;SFN
8	regulation of cell projection organization (GO:0031344)	0.0457552	0.1334988	DMTN;ITGA3;AGRN
8	negative regulation of protein modification process (GO:0031400)	0.0504857	0.1341754	DMTN;CD300A;SFN
8	regulation of cell activation (GO:0050865)	0.0544998	0.1379463	DMTN;TEC;CD300A
8	negative regulation of phosphorus metabolic process (GO:0010563)	0.0670867	0.1523060	DMTN;CD300A;SFN
8	negative regulation of phosphate metabolic process (GO:0045936)	0.0670867	0.1523060	DMTN;CD300A;SFN
8	negative regulation of cellular component organization (GO:0051129)	0.0727553	0.1585187	DMTN;CD300A;ITGA3
8	Arrhythmogenic right ventricular cardiomyopathy (ARVC) Homo sapiens hsa05412	0.0000000	0.0000000	DSP;CDH2;JUP;ITGB4;ITGA3;ITGB7;DSG2;CTNNA2;DSC2
8	ECM-receptor interaction Homo sapiens hsa04512	0.0000000	0.0000000	LAMA5;LAMB3;ITGB4;ITGA3;LAMC2;ITGB7;AGRN
8	Focal adhesion Homo sapiens hsa04510	0.0000033	0.0000451	LAMA5;LAMB3;ITGB4;ITGA3;LAMC2;ITGB7
8	Pathways in cancer Homo sapiens hsa05200	0.0000145	0.0001483	LAMA5;JUP;LAMB3;CDH1;ITGA3;LAMC2;CTNNA2
8	Small cell lung cancer Homo sapiens hsa05222	0.0000286	0.0002343	LAMA5;LAMB3;ITGA3;LAMC2
8	PI3K-Akt signaling pathway Homo sapiens hsa04151	0.0000639	0.0004366	LAMA5;LAMB3;ITGB4;ITGA3;LAMC2;ITGB7
8	Hypertrophic cardiomyopathy (HCM) Homo sapiens hsa05410	0.0006556	0.0038401	ITGB4;ITGA3;ITGB7
8	Dilated cardiomyopathy Homo sapiens hsa05414	0.0008300	0.0042538	ITGB4;ITGA3;ITGB7
8	Amoebiasis Homo sapiens hsa05146	0.0011263	0.0051310	LAMA5;LAMB3;LAMC2
8	Toxoplasmosis Homo sapiens hsa05145	0.0018124	0.0074308	LAMA5;LAMB3;LAMC2
8	Cell adhesion molecules (CAMs) Homo sapiens hsa04514	0.0030662	0.0114286	CDH2;CDH1;ITGB7
8	Regulation of actin cytoskeleton Homo sapiens hsa04810	0.0095491	0.0275753	ITGB4;ITGA3;ITGB7
8	Cell junction organization Homo sapiens R-HSA-446728	0.0000000	0.0000000	CDH6;CDH2;JUP;LAMB3;ITGB4;CDH1;LAMC2
8	Laminin interactions Homo sapiens R-HSA-3000157	0.0000000	0.0000000	LAMA5;LAMB3;ITGB4;ITGA3;LAMC2
8	Cell-Cell communication Homo sapiens R-HSA-1500931	0.0000000	0.0000003	CDH6;CDH2;JUP;LAMB3;ITGB4;CDH1;LAMC2
8	Non-integrin membrane-ECM interactions Homo sapiens R-HSA-3000171	0.0000000	0.0000005	LAMA5;LAMB3;ITGB4;LAMC2;AGRN
8	Extracellular matrix organization Homo sapiens R-HSA-1474244	0.0000001	0.0000018	LAMA5;LAMB3;ITGB4;CDH1;ITGA3;LAMC2;ITGB7;AGRN
8	Adherens junctions interactions Homo sapiens R-HSA-418990	0.0000005	0.0000074	CDH6;CDH2;JUP;CDH1
8	Type I hemidesmosome assembly Homo sapiens R-HSA-446107	0.0000007	0.0000092	LAMB3;ITGB4;LAMC2
8	Apoptotic cleavage of cell adhesion proteins Homo sapiens R-HSA-351906	0.0000013	0.0000158	DSP;CDH1;DSG2
8	Cell-cell junction organization Homo sapiens R-HSA-421270	0.0000073	0.0000785	CDH6;CDH2;JUP;CDH1
8	Integrin cell surface interactions Homo sapiens R-HSA-216083	0.0000106	0.0001029	CDH1;ITGA3;ITGB7;AGRN
8	Apoptotic cleavage of cellular proteins Homo sapiens R-HSA-111465	0.0000592	0.0005219	DSP;CDH1;DSG2
8	Degradation of the extracellular matrix Homo sapiens R-HSA-1474228	0.0000649	0.0005247	LAMA5;LAMB3;CDH1;LAMC2
8	Apoptotic execution phase Homo sapiens R-HSA-75153	0.0001555	0.0010775	DSP;CDH1;DSG2
8	Assembly of collagen fibrils and other multimeric structures Homo sapiens R-HSA-2022090	0.0001844	0.0011927	LAMB3;ITGB4;LAMC2
8	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Homo sapiens R-HSA-198933	0.0002952	0.0016842	CD96;CDH1;CD300A;ITGB7
8	Apoptosis Homo sapiens R-HSA-109581	0.0003404	0.0018344	DSP;CDH1;SFN;DSG2
8	Programmed Cell Death Homo sapiens R-HSA-5357801	0.0003648	0.0018624	DSP;CDH1;SFN;DSG2
8	Collagen formation Homo sapiens R-HSA-1474290	0.0007028	0.0034085	LAMB3;ITGB4;LAMC2
8	Adaptive Immune System Homo sapiens R-HSA-1280218	0.0191071	0.0597868	CD96;CDH1;CD300A;BLNK;ITGB7
8	Immune System Homo sapiens R-HSA-168256	0.0361104	0.0789546	CD96;TEC;CDH1;CD300A;TXK;BLNK;ITGB7
8	Transmembrane transport of small molecules Homo sapiens R-HSA-382551	0.1215623	0.1708919	DMTN;AQP9;AQP5
8	Developmental Biology Homo sapiens R-HSA-1266738	0.2173670	0.2635575	CDH2;CTNNA2;AGRN
8	Signal Transduction Homo sapiens R-HSA-162582	0.2357497	0.2823175	TEC;JUP;CDH1;SH2D2A;SFN;LRP2;AGRN
8	Metabolism Homo sapiens R-HSA-1430728	0.7634781	0.7795513	HAS2;LRP2;AGRN
8	Agrin in Postsynaptic Differentiation Homo sapiens h agrPathway	0.0000025	0.0000254	LAMA5;LAMB3;LAMC2;AGRN
8	Prion Pathway Homo sapiens h prionPathway	0.0000064	0.0000319	LAMA5;LAMB3;LAMC2
10	Phenylalanine metabolism Homo sapiens hsa00360	0.0000000	0.0000000	ALDH3A1;ALDH3B2;ALDH3B1
10	Histidine metabolism Homo sapiens hsa00340	0.0000000	0.0000000	ALDH3A1;ALDH3B2;ALDH3B1
10	beta-Alanine metabolism Homo sapiens hsa00410	0.0000000	0.0000000	ALDH3A1;ALDH3B2;ALDH3B1
10	Tyrosine metabolism Homo sapiens hsa00350	0.0000000	0.0000000	ALDH3A1;ALDH3B2;ALDH3B1
10	Glycolysis / Gluconeogenesis Homo sapiens hsa00010	0.0000000	0.0000001	ALDH3A1;ALDH3B2;ALDH3B1
10	Drug metabolism - cytochrome P450 Homo sapiens hsa00982	0.0000000	0.0000001	ALDH3A1;ALDH3B2;ALDH3B1
10	Metabolism of xenobiotics by cytochrome P450 Homo sapiens hsa00980	0.0000000	0.0000001	ALDH3A1;ALDH3B2;ALDH3B1
10	Chemical carcinogenesis Homo sapiens hsa05204	0.0000001	0.0000001	ALDH3A1;ALDH3B2;ALDH3B1
10	Metabolic pathways Homo sapiens hsa01100	0.0002372	0.0002372	ALDH3A1;ALDH3B2;ALDH3B1
10	Metabolism Homo sapiens R-HSA-1430728	0.0008670	0.0017340	ALDH3A1;ALDH3B2;ALDH3B1
13	regulation of leukocyte differentiation (GO:1902105)	0.0000006	0.0004512	LEF1;MYB;NRARP;IKZF3;FOXP3;LTF
13	leukocyte activation (GO:0045321)	0.0000010	0.0004512	SELPLG;ITGA4;LEF1;TCF7;MYB;IKZF3;FOXP3
13	leukocyte differentiation (GO:0002521)	0.0000017	0.0004894	ITGA4;LEF1;TCF7;MYB;FOXP3;MMP9
13	lymphocyte activation (GO:0046649)	0.0000051	0.0009192	ITGA4;LEF1;TCF7;MYB;IKZF3;FOXP3
13	lymphocyte differentiation (GO:0030098)	0.0000053	0.0009192	ITGA4;LEF1;TCF7;MYB;FOXP3
13	regulation of cell growth (GO:0001558)	0.0000071	0.0010271	ESM1;SOX17;LEF1;NRCAM;SEMA3F;MSX1
13	alpha-beta T cell differentiation (GO:0046632)	0.0000177	0.0021822	LEF1;TCF7;FOXP3
13	angiogenesis (GO:0001525)	0.0000246	0.0026553	ESM1;SOX17;ANPEP;LEF1;NRCAM
13	alpha-beta T cell activation (GO:0046631)	0.0000290	0.0027854	LEF1;TCF7;FOXP3
13	regulation of lymphocyte differentiation (GO:0045619)	0.0000340	0.0029449	MYB;NRARP;IKZF3;FOXP3
13	B cell activation (GO:0042113)	0.0000386	0.0030318	ITGA4;LEF1;MYB;IKZF3
13	cell morphogenesis involved in differentiation (GO:0000904)	0.0000662	0.0047691	SOX17;ITGA4;LEF1;MSX1
13	neuron projection guidance (GO:0097485)	0.0001977	0.0106509	KCNQ3;NRCAM;SEMA3F;RUNX3;SPTBN2
13	axon guidance (GO:0007411)	0.0001977	0.0106509	KCNQ3;NRCAM;SEMA3F;RUNX3;SPTBN2
13	cell morphogenesis (GO:0000902)	0.0002340	0.0106509	SOX17;ITGA4;LEF1;MSX1
13	canonical Wnt signaling pathway (GO:0060070)	0.0002673	0.0110117	SOX17;LEF1;TCF7
13	regulation of binding (GO:0051098)	0.0003013	0.0114623	ITGA4;LEF1;MSX1;MMP9
13	embryonic morphogenesis (GO:0048598)	0.0003048	0.0114623	SOX17;LEF1;TCF7;MSX1;FOXP4
13	negative regulation of binding (GO:0051100)	0.0003841	0.0129385	ITGA4;LEF1;MSX1
13	single organismal cell-cell adhesion (GO:0016337)	0.0004005	0.0129385	SELPLG;ITGA4;LEF1;NRCAM
13	regulation of T cell differentiation (GO:0045580)	0.0004083	0.0129385	MYB;NRARP;FOXP3
13	T cell differentiation (GO:0030217)	0.0004083	0.0129385	LEF1;TCF7;FOXP3
13	cellular component morphogenesis (GO:0032989)	0.0004418	0.0129385	SOX17;ITGA4;LEF1;NRCAM;MSX1
13	response to other organism (GO:0051707)	0.0005691	0.0133874	ANPEP;HP;LYZ;FOXP3;LTF
13	single organism cell adhesion (GO:0098602)	0.0005777	0.0133874	SELPLG;ITGA4;LEF1;NRCAM
13	transcription from RNA polymerase II promoter (GO:0006366)	0.0006152	0.0136449	SOX17;LEF1;MSX1;FOXP3;RUNX3
13	positive regulation of leukocyte differentiation (GO:1902107)	0.0007236	0.0146626	LEF1;MYB;FOXP3
13	ameboidal-type cell migration (GO:0001667)	0.0008163	0.0153492	SOX17;LEF1;SEMA3F
13	regulation of protein binding (GO:0043393)	0.0009162	0.0168612	ITGA4;LEF1;MMP9
13	epithelial cell differentiation (GO:0030855)	0.0010373	0.0181487	SOX17;LEF1;FOXP4;MUC5B
13	anterior/posterior pattern specification (GO:0009952)	0.0014471	0.0208617	SOX17;LEF1;MSX1
13	negative regulation of cell growth (GO:0030308)	0.0014471	0.0208617	SOX17;SEMA3F;MSX1
13	regulation of canonical Wnt signaling pathway (GO:0060828)	0.0015031	0.0213142	SOX17;LEF1;NRARP
13	regulation of lymphocyte activation (GO:0051249)	0.0016553	0.0223725	MYB;NRARP;IKZF3;FOXP3
13	tube development (GO:0035295)	0.0018679	0.0241158	SOX17;TCF7;MYB
13	tissue morphogenesis (GO:0048729)	0.0019149	0.0243593	SOX17;LEF1;NRARP;MSX1
13	heart development (GO:0007507)	0.0019670	0.0246591	VCAN;ITGA4;FOXP4
13	defense response to bacterium (GO:0042742)	0.0023960	0.0283914	HP;LYZ;LTF
13	pattern specification process (GO:0007389)	0.0024934	0.0286223	SOX17;LEF1;NRARP;MSX1
13	regulation of leukocyte activation (GO:0002694)	0.0026124	0.0286467	MYB;NRARP;IKZF3;FOXP3
13	negative regulation of cytokine production (GO:0001818)	0.0026306	0.0286467	LEF1;FOXP3;LTF
13	T cell activation (GO:0042110)	0.0031866	0.0332093	LEF1;TCF7;FOXP3
13	response to bacterium (GO:0009617)	0.0033243	0.0342325	HP;LYZ;LTF
13	regulation of cell activation (GO:0050865)	0.0034098	0.0347001	MYB;NRARP;IKZF3;FOXP3
13	regulation of Wnt signaling pathway (GO:0030111)	0.0039634	0.0381687	SOX17;LEF1;NRARP
13	negative regulation of response to external stimulus (GO:0032102)	0.0040154	0.0381687	SEMA3F;FOXP3;LTF
13	gland development (GO:0048732)	0.0042819	0.0402594	LEF1;MYB;MSX1
13	negative regulation of growth (GO:0045926)	0.0043365	0.0403339	SOX17;SEMA3F;MSX1
13	leukocyte migration (GO:0050900)	0.0046156	0.0424251	SELPLG;ITGA4;MMP9
13	Wnt signaling pathway (GO:0016055)	0.0050846	0.0448794	SOX17;LEF1;TCF7
13	regulation of cytokine production (GO:0001817)	0.0055561	0.0471180	LEF1;IGF2BP2;FOXP3;LTF
13	regionalization (GO:0003002)	0.0059063	0.0487390	SOX17;LEF1;MSX1
13	regulation of cell morphogenesis involved in differentiation (GO:0010769)	0.0059726	0.0487390	LEF1;NRCAM;SEMA3F
13	epithelium development (GO:0060429)	0.0065193	0.0508038	SOX17;TCF7;MSX1
13	regulation of T cell activation (GO:0050863)	0.0067318	0.0519913	MYB;NRARP;FOXP3
13	cellular response to organic cyclic compound (GO:0071407)	0.0092578	0.0646696	LEF1;MSX1;MUC5B
13	morphogenesis of an epithelium (GO:0002009)	0.0096962	0.0660409	SOX17;LEF1;NRARP
13	negative regulation of immune system process (GO:0002683)	0.0110836	0.0701297	NRARP;FOXP3;LTF
13	defense response to other organism (GO:0098542)	0.0127890	0.0702417	HP;LYZ;LTF
13	positive regulation of organelle organization (GO:0010638)	0.0140789	0.0724187	MYB;MSX1;FOXP3
13	extracellular matrix organization (GO:0030198)	0.0162686	0.0739884	VCAN;ITGA4;MMP9
13	extracellular structure organization (GO:0043062)	0.0163889	0.0739884	VCAN;ITGA4;MMP9
13	organ morphogenesis (GO:0009887)	0.0223283	0.0763400	LEF1;TCF7;MSX1
13	regulation of cell morphogenesis (GO:0022604)	0.0227611	0.0773233	LEF1;NRCAM;SEMA3F
13	posttranscriptional regulation of gene expression (GO:0010608)	0.0273425	0.0816549	SOX17;IGF2BP2;MSX1
13	cellular response to cytokine stimulus (GO:0071345)	0.0329145	0.0859597	SELPLG;LEF1;TCF7
13	coagulation (GO:0050817)	0.0330920	0.0859597	SELPLG;ITGA4;MYB
13	blood coagulation (GO:0007596)	0.0330920	0.0859597	SELPLG;ITGA4;MYB
13	negative regulation of cellular component organization (GO:0051129)	0.0334486	0.0861318	SEMA3F;FOXP3;SPTBN2
13	chromatin modification (GO:0016568)	0.0336277	0.0861318	LEF1;MYB;FOXP3
13	hemostasis (GO:0007599)	0.0341679	0.0864187	SELPLG;ITGA4;MYB
13	Cell adhesion molecules (CAMs) Homo sapiens hsa04514	0.0000578	0.0022551	VCAN;SELPLG;ITGA4;NRCAM
13	Arrhythmogenic right ventricular cardiomyopathy (ARVC) Homo sapiens hsa05412	0.0001837	0.0035826	ITGA4;LEF1;TCF7
13	Wnt signaling pathway Homo sapiens hsa04310	0.0012362	0.0119464	SOX17;LEF1;TCF7
13	Hippo signaling pathway Homo sapiens hsa04390	0.0015316	0.0119464	TEAD4;LEF1;TCF7
13	Pathways in cancer Homo sapiens hsa05200	0.0211969	0.0516674	LEF1;TCF7;MMP9
13	Interaction between L1 and Ankyrins Homo sapiens R-HSA-445095	0.0000108	0.0015173	KCNQ3;NRCAM;SPTBN2
13	Deactivation of the beta-catenin transactivating complex Homo sapiens R-HSA-3769402	0.0000336	0.0021216	SOX17;LEF1;TCF7
13	L1CAM interactions Homo sapiens R-HSA-373760	0.0003960	0.0110892	KCNQ3;NRCAM;SPTBN2
13	TCF dependent signaling in response to WNT Homo sapiens R-HSA-201681	0.0032321	0.0659311	SOX17;LEF1;TCF7
13	Axon guidance Homo sapiens R-HSA-422475	0.0070031	0.0731803	KCNQ3;NRCAM;MMP9;SPTBN2
13	Extracellular matrix organization Homo sapiens R-HSA-1474244	0.0085812	0.0731803	VCAN;ITGA4;MMP9
13	Signaling by Wnt Homo sapiens R-HSA-195721	0.0096075	0.0731803	SOX17;LEF1;TCF7
13	Metabolism of proteins Homo sapiens R-HSA-392499	0.0205815	0.1164969	ANPEP;LYZ;MUC5B;SPTBN2;LTF
13	Developmental Biology Homo sapiens R-HSA-1266738	0.0288128	0.1218412	KCNQ3;NRCAM;MMP9;SPTBN2
13	Hemostasis Homo sapiens R-HSA-109582	0.0489250	0.1700405	SELPLG;ITGA4;MYB
13	Disease Homo sapiens R-HSA-1643685	0.0935234	0.2484567	VCAN;MUC5B;LTF
13	Signal Transduction Homo sapiens R-HSA-162582	0.3079595	0.4675686	SOX17;LEF1;TCF7;MMP9;SPTBN2
13	Immune System Homo sapiens R-HSA-168256	0.4127921	0.4692040	ITGA4;SPTBN2;LTF
14	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)	0.0000000	0.0000000	CLDN6;CLDN10;CLDN4;CLDN3;CLDN9;CLDN7;CLDN16;CLDN1
14	cell-cell junction organization (GO:0045216)	0.0000000	0.0000000	CLDN6;GJB2;OCLN;CXADR;GJB1;CLDN9;MARVELD3;CLDN1;CRB3
14	cell junction organization (GO:0034330)	0.0000000	0.0000000	CLDN6;GJB2;OCLN;CXADR;GJB1;CLDN9;MARVELD3;CLDN1;CRB3
14	cell-cell adhesion via plasma-membrane adhesion molecules (GO:0098742)	0.0000000	0.0000000	CLDN6;CLDN10;CLDN4;CXADR;CLDN3;CLDN9;CLDN7;CLDN16;CLDN1
14	cell-cell adhesion (GO:0098609)	0.0000000	0.0000000	CLDN6;CLDN10;CLDN4;CXADR;CLDN3;CLDN9;CLDN7;CLDN16;CLDN1
14	cell-cell junction assembly (GO:0007043)	0.0000000	0.0000001	GJB2;OCLN;GJB1;CLDN9;MARVELD3;CRB3
14	cell junction assembly (GO:0034329)	0.0000001	0.0000036	GJB2;OCLN;GJB1;CLDN9;MARVELD3;CRB3
14	tight junction assembly (GO:0070830)	0.0000002	0.0000108	OCLN;CLDN9;MARVELD3;CRB3
14	coagulation (GO:0050817)	0.0034942	0.0836724	APBB1IP;NRAS;CXADR;PRKCZ
14	blood coagulation (GO:0007596)	0.0034942	0.0836724	APBB1IP;NRAS;CXADR;PRKCZ
14	hemostasis (GO:0007599)	0.0036556	0.0836724	APBB1IP;NRAS;CXADR;PRKCZ
14	actin cytoskeleton organization (GO:0030036)	0.0046750	0.0970680	NRAS;CXADR;PRKCZ
14	actin filament-based process (GO:0030029)	0.0076943	0.1378288	NRAS;CXADR;PRKCZ
14	response to peptide hormone (GO:0043434)	0.0126532	0.1434880	NRAS;STC2;PRKCZ
14	response to peptide (GO:1901652)	0.0145991	0.1434880	NRAS;STC2;PRKCZ
14	positive regulation of MAPK cascade (GO:0043410)	0.0157382	0.1434880	NRAS;KSR2;PRKCZ
14	Tight junction Homo sapiens hsa04530	0.0000000	0.0000000	CGN;CLDN1;PRKCZ;CLDN6;CLDN10;NRAS;CLDN4;OCLN;CLDN3;CLDN9;CLDN7;CLDN16;TJP3;CRB3;LLGL2
14	Hepatitis C Homo sapiens hsa05160	0.0000000	0.0000000	CLDN6;CLDN10;NRAS;CLDN4;OCLN;CLDN3;CLDN9;CLDN7;CLDN16;CLDN1
14	Leukocyte transendothelial migration Homo sapiens hsa04670	0.0000000	0.0000000	CLDN6;CLDN10;CLDN4;OCLN;CLDN3;CLDN9;CLDN7;CLDN16;CLDN1
14	Cell adhesion molecules (CAMs) Homo sapiens hsa04514	0.0000000	0.0000000	CLDN6;CLDN10;CLDN4;OCLN;CLDN3;CLDN9;CLDN7;CLDN16;CLDN1
14	Rap1 signaling pathway Homo sapiens hsa04015	0.0028091	0.0299642	APBB1IP;NRAS;PRKCZ
14	Ras signaling pathway Homo sapiens hsa04014	0.0034516	0.0315571	NRAS;RASAL1;KSR2
14	Tight junction interactions Homo sapiens R-HSA-420029	0.0000000	0.0000000	CLDN6;CLDN10;CLDN4;CLDN3;CLDN9;CLDN7;CLDN16;CLDN1;CRB3
14	Cell-cell junction organization Homo sapiens R-HSA-421270	0.0000000	0.0000000	CLDN6;CLDN10;CLDN4;CLDN3;CLDN9;CLDN7;CLDN16;CLDN1;CRB3
14	Cell junction organization Homo sapiens R-HSA-446728	0.0000000	0.0000000	CLDN6;CLDN10;CLDN4;CLDN3;CLDN9;CLDN7;CLDN16;CLDN1;CRB3
14	Cell-Cell communication Homo sapiens R-HSA-1500931	0.0000000	0.0000000	CLDN6;CLDN10;CLDN4;CLDN3;CLDN9;CLDN7;CLDN16;CLDN1;CRB3
14	MAP2K and MAPK activation Homo sapiens R-HSA-5674135	0.0000002	0.0000048	APBB1IP;CNKSR1;NRAS;KSR2
14	VEGFR2 mediated cell proliferation Homo sapiens R-HSA-5218921	0.0000008	0.0000172	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2;PRKCZ
14	Gap junction assembly Homo sapiens R-HSA-190861	0.0000021	0.0000380	GJB2;GJB1;GJB3
14	VEGFA-VEGFR2 Pathway Homo sapiens R-HSA-4420097	0.0000036	0.0000567	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2;PRKCZ
14	Signaling by VEGF Homo sapiens R-HSA-194138	0.0000041	0.0000580	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2;PRKCZ
14	Gap junction trafficking Homo sapiens R-HSA-190828	0.0000070	0.0000793	GJB2;GJB1;GJB3
14	Gap junction trafficking and regulation Homo sapiens R-HSA-157858	0.0000087	0.0000793	GJB2;GJB1;GJB3
14	GRB2 events in EGFR signaling Homo sapiens R-HSA-179812	0.0000140	0.0000793	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	SHC1 events in EGFR signaling Homo sapiens R-HSA-180336	0.0000140	0.0000793	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	SOS-mediated signalling Homo sapiens R-HSA-112412	0.0000140	0.0000793	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	SHC1 events in ERBB4 signaling Homo sapiens R-HSA-1250347	0.0000140	0.0000793	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	RAF/MAP kinase cascade Homo sapiens R-HSA-5673001	0.0000140	0.0000793	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	FRS-mediated FGFR2 signaling Homo sapiens R-HSA-5654700	0.0000143	0.0000793	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	FRS-mediated FGFR4 signaling Homo sapiens R-HSA-5654712	0.0000143	0.0000793	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	FRS-mediated FGFR3 signaling Homo sapiens R-HSA-5654706	0.0000143	0.0000793	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	FRS-mediated FGFR1 signaling Homo sapiens R-HSA-5654693	0.0000143	0.0000793	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	ARMS-mediated activation Homo sapiens R-HSA-170984	0.0000152	0.0000793	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Signalling to p38 via RIT and RIN Homo sapiens R-HSA-187706	0.0000152	0.0000793	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Frs2-mediated activation Homo sapiens R-HSA-170968	0.0000155	0.0000793	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	MAPK1/MAPK3 signaling Homo sapiens R-HSA-5684996	0.0000158	0.0000793	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Prolonged ERK activation events Homo sapiens R-HSA-169893	0.0000162	0.0000793	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Signaling by Leptin Homo sapiens R-HSA-2586552	0.0000165	0.0000793	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Interleukin receptor SHC signaling Homo sapiens R-HSA-912526	0.0000172	0.0000793	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Signalling to RAS Homo sapiens R-HSA-167044	0.0000175	0.0000793	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Interleukin-2 signaling Homo sapiens R-HSA-451927	0.0000196	0.0000847	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Signalling to ERKs Homo sapiens R-HSA-187687	0.0000200	0.0000847	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Interleukin-3, 5 and GM-CSF signaling Homo sapiens R-HSA-512988	0.0000232	0.0000952	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	NCAM signaling for neurite out-growth Homo sapiens R-HSA-375165	0.0000255	0.0001010	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	IRS-mediated signalling Homo sapiens R-HSA-112399	0.0000348	0.0001233	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	MAPK family signaling cascades Homo sapiens R-HSA-5683057	0.0000348	0.0001233	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Insulin receptor signalling cascade Homo sapiens R-HSA-74751	0.0000366	0.0001233	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	IGF1R signaling cascade Homo sapiens R-HSA-2428924	0.0000372	0.0001233	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) Homo sapiens R-HSA-2404192	0.0000372	0.0001233	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	IRS-related events triggered by IGF1R Homo sapiens R-HSA-2428928	0.0000372	0.0001233	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	FCERI mediated MAPK activation Homo sapiens R-HSA-2871796	0.0000378	0.0001233	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Axon guidance Homo sapiens R-HSA-422475	0.0000529	0.0001662	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2;EPHA1
14	Signaling by Insulin receptor Homo sapiens R-HSA-74752	0.0000537	0.0001662	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Signaling by SCF-KIT Homo sapiens R-HSA-1433557	0.0000661	0.0001922	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Downstream signaling of activated FGFR2 Homo sapiens R-HSA-5654696	0.0000700	0.0001922	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Downstream signaling of activated FGFR4 Homo sapiens R-HSA-5654716	0.0000700	0.0001922	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Downstream signaling of activated FGFR3 Homo sapiens R-HSA-5654708	0.0000700	0.0001922	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Signaling by ERBB4 Homo sapiens R-HSA-1236394	0.0000711	0.0001922	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Signaling by FGFR4 Homo sapiens R-HSA-5654743	0.0000731	0.0001922	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Downstream signaling of activated FGFR1 Homo sapiens R-HSA-5654687	0.0000731	0.0001922	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Signaling by FGFR3 Homo sapiens R-HSA-5654741	0.0000742	0.0001922	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Signaling by FGFR1 Homo sapiens R-HSA-5654736	0.0000774	0.0001965	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Downstream signal transduction Homo sapiens R-HSA-186763	0.0000830	0.0002066	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	DAP12 signaling Homo sapiens R-HSA-2424491	0.0000865	0.0002111	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Signaling by EGFR Homo sapiens R-HSA-177929	0.0001003	0.0002402	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	DAP12 interactions Homo sapiens R-HSA-2172127	0.0001057	0.0002485	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Signaling by FGFR2 Homo sapiens R-HSA-5654738	0.0001085	0.0002505	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Signaling by PDGF Homo sapiens R-HSA-186797	0.0001128	0.0002557	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Signaling by FGFR Homo sapiens R-HSA-190236	0.0001157	0.0002578	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	NGF signalling via TRKA from the plasma membrane Homo sapiens R-HSA-187037	0.0001280	0.0002804	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Signaling by Interleukins Homo sapiens R-HSA-449147	0.0001595	0.0003433	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Fc epsilon receptor (FCERI) signaling Homo sapiens R-HSA-2454202	0.0001653	0.0003498	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Gastrin-CREB signalling pathway via PKC and MAPK Homo sapiens R-HSA-881907	0.0002505	0.0005130	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Signalling by NGF Homo sapiens R-HSA-166520	0.0003024	0.0006096	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Developmental Biology Homo sapiens R-HSA-1266738	0.0005269	0.0010455	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2;EPHA1
14	Cytokine Signaling in Immune system Homo sapiens R-HSA-1280215	0.0012909	0.0024840	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Innate Immune System Homo sapiens R-HSA-168249	0.0040710	0.0074929	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Hemostasis Homo sapiens R-HSA-109582	0.0060835	0.0108817	APBB1IP;NRAS;CXADR;PRKCZ
14	Immune System Homo sapiens R-HSA-168256	0.0153073	0.0246080	APBB1IP;CNKSR1;NRAS;CXADR;RASAL1;KSR2
14	Membrane Trafficking Homo sapiens R-HSA-199991	0.0185110	0.0286694	GJB2;GJB1;GJB3
14	Signaling by GPCR Homo sapiens R-HSA-372790	0.0274960	0.0366390	APBB1IP;CNKSR1;NRAS;RASAL1;KSR2
14	Vesicle-mediated transport Homo sapiens R-HSA-5653656	0.0279378	0.0366390	GJB2;GJB1;GJB3
14	Signal Transduction Homo sapiens R-HSA-162582	0.0410415	0.0501180	APBB1IP;CNKSR1;NRAS;RASAL1;CGN;KSR2;PRKCZ
15	synaptic transmission (GO:0007268)	0.0000000	0.0000021	GNGT1;GRIN2A;KCNJ12;CACNA1B;GRIK3;CACNA1A;HTR3A;CACNG4;GRIN2D
15	inorganic cation transmembrane transport (GO:0098662)	0.0000000	0.0000021	RYR1;GRIN2A;KCNJ12;SCNN1A;CACNA1B;CACNA1A;HTR3A;CACNA1F;CACNG4
15	calcium ion transport (GO:0006816)	0.0000000	0.0000036	RYR1;GRIN2A;CACNA1B;CACNA1A;CACNA1F;JPH1;CACNG4
15	calcium ion transmembrane transport (GO:0070588)	0.0000000	0.0000036	RYR1;GRIN2A;CACNA1B;CACNA1A;CACNA1F;CACNG4
15	divalent metal ion transport (GO:0070838)	0.0000000	0.0000036	RYR1;GRIN2A;CACNA1B;CACNA1A;CACNA1F;JPH1;CACNG4
15	divalent inorganic cation transport (GO:0072511)	0.0000000	0.0000036	RYR1;GRIN2A;CACNA1B;CACNA1A;CACNA1F;JPH1;CACNG4
15	synaptic transmission, glutamatergic (GO:0035249)	0.0000002	0.0000164	GRIN2A;GRIK3;CACNA1A;GRIN2D
15	membrane depolarization (GO:0051899)	0.0000004	0.0000288	GRIN2A;CACNA1B;CACNA1A;CACNA1F;CACNG4
15	neuron differentiation (GO:0030182)	0.0000007	0.0000420	WNT10A;WNT11;FZD2;CABP4;WNT7B;CACNA1A
15	neuron-neuron synaptic transmission (GO:0007270)	0.0000014	0.0000808	GRIN2A;GRIK3;CACNA1A;GRIN2D
15	regulation of membrane potential (GO:0042391)	0.0000019	0.0000985	GRIN2A;CACNA1B;GRIK3;CACNA1A;CACNA1F;CACNG4
15	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger (GO:0007187)	0.0000025	0.0001181	GNA15;FZD2;RGS1;APLP1;GRIK3
15	regulation of ion transmembrane transport (GO:0034765)	0.0000050	0.0002170	KCNJ12;CACNA1B;CACNA1A;CACNA1F;JPH1;CACNG4
15	ionotropic glutamate receptor signaling pathway (GO:0035235)	0.0000054	0.0002189	GRIN2A;GRIK3;GRIN2D
15	regulation of transmembrane transport (GO:0034762)	0.0000063	0.0002373	KCNJ12;CACNA1B;CACNA1A;CACNA1F;JPH1;CACNG4
15	calcium ion import (GO:0070509)	0.0000132	0.0004658	CACNA1B;CACNA1A;CACNA1F
15	membrane depolarization during action potential (GO:0086010)	0.0000223	0.0006820	CACNA1B;CACNA1A;CACNA1F
15	regulation of synaptic transmission (GO:0050804)	0.0000247	0.0006820	GRIN2A;GRIK3;CACNA1A;SHISA9;LRP8
15	outflow tract morphogenesis (GO:0003151)	0.0000261	0.0006820	RYR1;WNT11;FZD2
15	glutamate receptor signaling pathway (GO:0007215)	0.0000261	0.0006820	GRIN2A;GRIK3;GRIN2D
15	metal ion homeostasis (GO:0055065)	0.0000268	0.0006820	RYR1;GNA15;SCNN1A;CACNA1A;CACNA1F;JPH1
15	detection of light stimulus (GO:0009583)	0.0000269	0.0006820	GNGT1;CABP4;CACNA1F;LRP8
15	adenylate cyclase-modulating G-protein coupled receptor signaling pathway (GO:0007188)	0.0000278	0.0006820	GNA15;RGS1;APLP1;GRIK3
15	cellular calcium ion homeostasis (GO:0006874)	0.0000335	0.0007866	RYR1;GNA15;CACNA1A;CACNA1F;JPH1
15	cellular divalent inorganic cation homeostasis (GO:0072503)	0.0000401	0.0009035	RYR1;GNA15;CACNA1A;CACNA1F;JPH1
15	calcium ion homeostasis (GO:0055074)	0.0000422	0.0009156	RYR1;GNA15;CACNA1A;CACNA1F;JPH1
15	cation homeostasis (GO:0055080)	0.0000461	0.0009633	RYR1;GNA15;SCNN1A;CACNA1A;CACNA1F;JPH1
15	divalent inorganic cation homeostasis (GO:0072507)	0.0000562	0.0011317	RYR1;GNA15;CACNA1A;CACNA1F;JPH1
15	positive regulation of cytosolic calcium ion concentration (GO:0007204)	0.0000657	0.0012774	RYR1;GNA15;CACNA1A;JPH1
15	response to light stimulus (GO:0009416)	0.0000906	0.0017042	GNGT1;GRIN2A;CABP4;CACNA1F;LRP8
15	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway (GO:0007193)	0.0000979	0.0017805	RGS1;APLP1;GRIK3
15	detection of external stimulus (GO:0009581)	0.0001134	0.0018676	GNGT1;CABP4;CACNA1F;LRP8
15	neuron projection morphogenesis (GO:0048812)	0.0001134	0.0018676	FZD2;WNT7B;CACNA1A;CACNA1F
15	cytosolic calcium ion homeostasis (GO:0051480)	0.0001159	0.0018676	RYR1;GNA15;CACNA1A;JPH1
15	detection of abiotic stimulus (GO:0009582)	0.0001211	0.0018966	GNGT1;CABP4;CACNA1F;LRP8
15	cellular metal ion homeostasis (GO:0006875)	0.0001549	0.0022991	RYR1;GNA15;CACNA1A;CACNA1F;JPH1
15	neuromuscular process (GO:0050905)	0.0002013	0.0029106	GRIN2A;CACNA1A;GRIN2D
15	cellular cation homeostasis (GO:0030003)	0.0002192	0.0030914	RYR1;GNA15;CACNA1A;CACNA1F;JPH1
15	canonical Wnt signaling pathway (GO:0060070)	0.0002413	0.0033198	WNT11;FZD2;WNT7B
15	cellular ion homeostasis (GO:0006873)	0.0002553	0.0034279	RYR1;GNA15;CACNA1A;CACNA1F;JPH1
15	cell projection morphogenesis (GO:0048858)	0.0003123	0.0040033	FZD2;WNT7B;CACNA1A;CACNA1F
15	Wnt signaling pathway (GO:0016055)	0.0003447	0.0043199	WNT10A;WNT11;FZD2;WNT7B
15	cellular component morphogenesis (GO:0032989)	0.0003749	0.0045960	FZD2;CABP4;WNT7B;CACNA1A;CACNA1F
15	response to radiation (GO:0009314)	0.0003949	0.0047388	GNGT1;GRIN2A;CABP4;CACNA1F;LRP8
15	cell part morphogenesis (GO:0032990)	0.0004294	0.0050351	FZD2;WNT7B;CACNA1A;CACNA1F
15	cellular chemical homeostasis (GO:0055082)	0.0004374	0.0050351	RYR1;GNA15;CACNA1A;CACNA1F;JPH1
15	detection of visible light (GO:0009584)	0.0004523	0.0050867	GNGT1;CACNA1F;LRP8
15	sensory perception (GO:0007600)	0.0004600	0.0050867	GRIN2A;FZD2;CABP4;SCNN1A;CACNA1F
15	phototransduction (GO:0007602)	0.0005189	0.0054200	GNGT1;CABP4;LRP8
15	neuron development (GO:0048666)	0.0007036	0.0072151	GNGT1;FZD2;CABP4
15	cell fate commitment (GO:0045165)	0.0009459	0.0093596	WNT10A;WNT11;WNT7B
15	regulation of G-protein coupled receptor protein signaling pathway (GO:0008277)	0.0010084	0.0094793	GNGT1;RGS19;RGS1
15	regulation of calcium ion transport (GO:0051924)	0.0019056	0.0154479	FKBP1C;CACNA1B;JPH1
15	regulation of system process (GO:0044057)	0.0019173	0.0154479	GRIN2A;KCNJ12;CACNA1B;GRIN2D
15	locomotory behavior (GO:0007626)	0.0023113	0.0181049	CACNA1B;CACNA1A;GRIN2D
15	behavior (GO:0007610)	0.0053516	0.0382063	GRIN2A;CACNA1B;CACNA1A;GRIN2D
15	regulation of metal ion transport (GO:0010959)	0.0055465	0.0391030	FKBP1C;CACNA1B;JPH1
15	epithelium development (GO:0060429)	0.0059227	0.0412395	WNT10A;WNT11;WNT7B
15	response to alcohol (GO:0097305)	0.0071420	0.0483014	GRIN2A;HTR3A;LRP8
15	cellular response to organic cyclic compound (GO:0071407)	0.0084213	0.0545309	RYR1;APLP1;LRP8
15	cellular response to lipid (GO:0071396)	0.0104447	0.0632074	WNT11;WNT7B;LRP8
15	tissue morphogenesis (GO:0048729)	0.0147255	0.0692824	WNT10A;WNT11;WNT7B
15	single-organism behavior (GO:0044708)	0.0151673	0.0692824	GRIN2A;CACNA1A;GRIN2D
15	monovalent inorganic cation transport (GO:0015672)	0.0177323	0.0702830	KCNJ12;SCNN1A;HTR3A
15	organ morphogenesis (GO:0009887)	0.0203948	0.0728017	WNT10A;WNT7B;APLP1
15	positive regulation of protein kinase activity (GO:0045860)	0.0277384	0.0877180	WNT11;WNT7B;LRP8
15	positive regulation of kinase activity (GO:0033674)	0.0316250	0.0903528	WNT11;WNT7B;LRP8
15	positive regulation of GTPase activity (GO:0043547)	0.0319613	0.0903528	RGS19;WNT11;RGS1
15	positive regulation of GTP catabolic process (GO:0033126)	0.0321302	0.0903528	RGS19;WNT11;RGS1
15	Calcium signaling pathway Homo sapiens hsa04020	0.0000000	0.0000003	RYR1;GNA15;GRIN2A;CACNA1B;CACNA1A;CACNA1F;GRIN2D
15	Nicotine addiction Homo sapiens hsa05033	0.0000003	0.0000067	GRIN2A;CACNA1B;CACNA1A;GRIN2D
15	Cholinergic synapse Homo sapiens hsa04725	0.0000005	0.0000067	GNGT1;KCNJ12;CACNA1B;CACNA1A;CACNA1F
15	Serotonergic synapse Homo sapiens hsa04726	0.0000005	0.0000067	GNGT1;CACNA1B;CACNA1A;HTR3A;CACNA1F
15	Glutamatergic synapse Homo sapiens hsa04724	0.0000006	0.0000067	GNGT1;GRIN2A;GRIK3;CACNA1A;GRIN2D
15	Basal cell carcinoma Homo sapiens hsa05217	0.0000012	0.0000110	WNT10A;WNT11;FZD2;WNT7B
15	GABAergic synapse Homo sapiens hsa04727	0.0000076	0.0000622	GNGT1;CACNA1B;CACNA1A;CACNA1F
15	Circadian entrainment Homo sapiens hsa04713	0.0000104	0.0000738	RYR1;GNGT1;GRIN2A;GRIN2D
15	Melanogenesis Homo sapiens hsa04916	0.0000127	0.0000753	WNT10A;WNT11;FZD2;WNT7B
15	Retrograde endocannabinoid signaling Homo sapiens hsa04723	0.0000132	0.0000753	GNGT1;CACNA1B;CACNA1A;CACNA1F
15	Dopaminergic synapse Homo sapiens hsa04728	0.0000346	0.0001794	GNGT1;GRIN2A;CACNA1B;CACNA1A
15	Wnt signaling pathway Homo sapiens hsa04310	0.0000504	0.0002089	WNT10A;WNT11;FZD2;WNT7B
15	Signaling pathways regulating pluripotency of stem cells Homo sapiens hsa04550	0.0000504	0.0002089	WNT10A;WNT11;FZD2;WNT7B
15	Hedgehog signaling pathway Homo sapiens hsa04340	0.0000513	0.0002089	WNT10A;WNT11;WNT7B
15	Hippo signaling pathway Homo sapiens hsa04390	0.0000674	0.0002560	WNT10A;WNT11;FZD2;WNT7B
15	Oxytocin signaling pathway Homo sapiens hsa04921	0.0000763	0.0002720	RYR1;KCNJ12;CACNA1F;CACNG4
15	Proteoglycans in cancer Homo sapiens hsa05205	0.0002006	0.0006725	WNT10A;WNT11;FZD2;WNT7B
15	Taste transduction Homo sapiens hsa04742	0.0002329	0.0007228	SCNN1A;CACNA1A;HTR3A
15	Pathways in cancer Homo sapiens hsa05200	0.0002409	0.0007228	GNGT1;WNT10A;WNT11;FZD2;WNT7B
15	Morphine addiction Homo sapiens hsa05032	0.0003056	0.0008710	GNGT1;CACNA1B;CACNA1A
15	MAPK signaling pathway Homo sapiens hsa04010	0.0004770	0.0012915	CACNA1B;CACNA1A;CACNA1F;CACNG4
15	HTLV-I infection Homo sapiens hsa05166	0.0004985	0.0012915	WNT10A;WNT11;FZD2;WNT7B
15	Alzheimer’s disease Homo sapiens hsa05010	0.0018118	0.0044901	GRIN2A;CACNA1F;GRIN2D
15	Alcoholism Homo sapiens hsa05034	0.0021706	0.0050095	GNGT1;GRIN2A;GRIN2D
15	cAMP signaling pathway Homo sapiens hsa04024	0.0029301	0.0059649	GRIN2A;CACNA1F;GRIN2D
15	Neuroactive ligand-receptor interaction Homo sapiens hsa04080	0.0073586	0.0115741	GRIN2A;GRIK3;GRIN2D
15	Neuronal System Homo sapiens R-HSA-112316	0.0000000	0.0000000	GNGT1;GRIN2A;LRFN4;KCNJ12;LRFN1;CACNA1B;GRIK3;CACNA1A;PTPRF;CACNG4;GRIN2D
15	SALM protein interactions at the synapse Homo sapiens R-HSA-8849932	0.0000000	0.0000000	GRIN2A;LRFN4;LRFN1;PTPRF;GRIN2D
15	Transmission across Chemical Synapses Homo sapiens R-HSA-112315	0.0000000	0.0000000	GNGT1;GRIN2A;KCNJ12;CACNA1B;GRIK3;CACNA1A;CACNG4;GRIN2D
15	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Homo sapiens R-HSA-112314	0.0000000	0.0000019	GNGT1;GRIN2A;KCNJ12;GRIK3;CACNG4;GRIN2D
15	Class B/2 (Secretin family receptors) Homo sapiens R-HSA-373080	0.0000001	0.0000040	GNGT1;WNT10A;WNT11;FZD2;WNT7B
15	Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels Homo sapiens R-HSA-112308	0.0000008	0.0000206	CACNA1B;CACNA1A;CACNG4
15	WNT ligand biogenesis and trafficking Homo sapiens R-HSA-3238698	0.0000070	0.0001576	WNT10A;WNT11;WNT7B
15	Signaling by GPCR Homo sapiens R-HSA-372790	0.0000079	0.0001576	GNGT1;GNA15;GRIN2A;WNT10A;RGS19;WNT11;FZD2;RGS1;WNT7B;GRIN2D
15	Cardiac conduction Homo sapiens R-HSA-5576891	0.0000414	0.0007307	RYR1;KCNJ12;CACNA1F;CACNG4
15	Signaling by Wnt Homo sapiens R-HSA-195721	0.0000599	0.0009531	GNGT1;WNT10A;WNT11;FZD2;WNT7B
15	Ca2+ pathway Homo sapiens R-HSA-4086398	0.0000932	0.0013474	GNGT1;WNT11;FZD2
15	Muscle contraction Homo sapiens R-HSA-397014	0.0001753	0.0023233	RYR1;KCNJ12;CACNA1F;CACNG4
15	Regulation of insulin secretion Homo sapiens R-HSA-422356	0.0002089	0.0023927	GNGT1;GNA15;CACNA1A
15	Gastrin-CREB signalling pathway via PKC and MAPK Homo sapiens R-HSA-881907	0.0003556	0.0033257	GNGT1;GNA15;GRIN2A;RGS19;GRIN2D
15	Signal Transduction Homo sapiens R-HSA-162582	0.0004015	0.0033317	GNGT1;GNA15;GRIN2A;WNT10A;RGS19;WNT11;FZD2;RGS1;WNT7B;LRP8;GRIN2D
15	GPCR ligand binding Homo sapiens R-HSA-500792	0.0004158	0.0033317	GNGT1;WNT10A;WNT11;FZD2;WNT7B
15	Integration of energy metabolism Homo sapiens R-HSA-163685	0.0005330	0.0036481	GNGT1;GNA15;CACNA1A
15	Beta-catenin independent WNT signaling Homo sapiens R-HSA-3858494	0.0011644	0.0053268	GNGT1;WNT11;FZD2
15	G alpha (q) signalling events Homo sapiens R-HSA-416476	0.0026093	0.0101190	GNGT1;GNA15;RGS19
15	Ion channel transport Homo sapiens R-HSA-983712	0.0030993	0.0114602	RYR1;SCNN1A;HTR3A
15	G alpha (i) signalling events Homo sapiens R-HSA-418594	0.0049525	0.0178965	GNGT1;RGS19;RGS1
15	Transmembrane transport of small molecules Homo sapiens R-HSA-382551	0.0101450	0.0322612	RYR1;GNGT1;SCNN1A;HTR3A
15	Hemostasis Homo sapiens R-HSA-109582	0.0449227	0.0866530	GNGT1;GNA15;LRP8
15	GPCR downstream signaling Homo sapiens R-HSA-388396	0.0518632	0.0866530	GNGT1;GNA15;RGS19;RGS1
15	Developmental Biology Homo sapiens R-HSA-1266738	0.1039179	0.1188701	GRIN2A;CACNG4;GRIN2D
15	Metabolism Homo sapiens R-HSA-1430728	0.2977192	0.3093944	GNGT1;GNA15;CACNA1A;LRP8
16	electron transport chain (GO:0022900)	0.0000000	0.0000000	NDUFB9;COX7B;NDUFB7;NDUFB11;NDUFA3;NDUFB3;COX5B;COX5A;COX6B1;NDUFS8;WDR93;UQCRFS1;CYC1
16	respiratory electron transport chain (GO:0022904)	0.0000000	0.0000000	NDUFB9;COX7B;NDUFB7;NDUFS8;NDUFB11;NDUFA3;NDUFB3;UQCRFS1;CYC1;COX5B;COX5A;COX6B1
16	generation of precursor metabolites and energy (GO:0006091)	0.0000000	0.0000000	CEBPA;NDUFB9;COX7B;NDUFB7;NDUFB11;NDUFA3;NDUFB3;COX5B;COX5A;COX6B1;NDUFS8;WDR93;UQCRFS1;CYC1
16	mitochondrial electron transport, NADH to ubiquinone (GO:0006120)	0.0000000	0.0000002	NDUFB9;NDUFB7;NDUFS8;NDUFA3;NDUFB3
16	hydrogen ion transmembrane transport (GO:1902600)	0.0000003	0.0000149	COX7B;UQCRFS1;COX5B;COX5A;COX6B1
16	proton transport (GO:0015992)	0.0000007	0.0000300	COX7B;UQCRFS1;COX5B;COX5A;COX6B1
16	hydrogen transport (GO:0006818)	0.0000007	0.0000300	COX7B;UQCRFS1;COX5B;COX5A;COX6B1
16	inflammatory response (GO:0006954)	0.0001086	0.0033809	CEBPA;CIITA;CXCR3;CHI3L1;PTGS1
16	monovalent inorganic cation transport (GO:0015672)	0.0001199	0.0033809	COX7B;UQCRFS1;COX5B;COX5A;COX6B1
16	inorganic cation transmembrane transport (GO:0098662)	0.0002262	0.0055795	COX7B;UQCRFS1;COX5B;COX5A;COX6B1
16	cellular response to cytokine stimulus (GO:0071345)	0.0030093	0.0556711	CEBPA;CIITA;CXCR3;CHI3L1
16	cellular response to organic cyclic compound (GO:0071407)	0.0061872	0.0963893	CEBPA;CIITA;KLF5
16	cytokine-mediated signaling pathway (GO:0019221)	0.0096288	0.1247250	CEBPA;CIITA;CXCR3
16	Non-alcoholic fatty liver disease (NAFLD) Homo sapiens hsa04932	0.0000000	0.0000000	CEBPA;NDUFB9;COX7B;NDUFB7;NDUFB11;NDUFA3;NDUFB3;NDUFA4L2;COX5B;COX5A;COX6B1;NDUFS8;UQCRFS1;CYC1
16	Oxidative phosphorylation Homo sapiens hsa00190	0.0000000	0.0000000	NDUFB9;COX7B;NDUFB7;NDUFB11;NDUFA3;NDUFB3;NDUFA4L2;COX5B;COX5A;COX6B1;NDUFS8;UQCRFS1;CYC1
16	Parkinson’s disease Homo sapiens hsa05012	0.0000000	0.0000000	NDUFB9;COX7B;NDUFB7;NDUFB11;NDUFA3;NDUFB3;NDUFA4L2;COX5B;COX5A;COX6B1;NDUFS8;UQCRFS1;CYC1
16	Alzheimer’s disease Homo sapiens hsa05010	0.0000000	0.0000000	NDUFB9;COX7B;NDUFB7;NDUFB11;NDUFA3;NDUFB3;NDUFA4L2;COX5B;COX5A;COX6B1;NDUFS8;UQCRFS1;CYC1
16	Huntington’s disease Homo sapiens hsa05016	0.0000000	0.0000000	NDUFB9;COX7B;NDUFB7;NDUFB11;NDUFA3;NDUFB3;NDUFA4L2;COX5B;COX5A;COX6B1;NDUFS8;UQCRFS1;CYC1
16	Metabolic pathways Homo sapiens hsa01100	0.0000000	0.0000000	NDUFB9;COX7B;NDUFB7;NDUFB11;NDUFA3;NDUFB3;NDUFA4L2;COX5B;COX5A;PTGS1;COX6B1;NDUFS8;UQCRFS1;CYC1
16	Cardiac muscle contraction Homo sapiens hsa04260	0.0000000	0.0000000	COX7B;UQCRFS1;CYC1;COX5B;COX5A;COX6B1
16	Respiratory electron transport Homo sapiens R-HSA-611105	0.0000000	0.0000000	NDUFB9;COX7B;NDUFB7;NDUFS8;NDUFB11;NDUFA3;NDUFB3;UQCRFS1;CYC1;COX5B;COX5A;COX6B1
16	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Homo sapiens R-HSA-163200	0.0000000	0.0000000	NDUFB9;COX7B;NDUFB7;NDUFS8;NDUFB11;NDUFA3;NDUFB3;UQCRFS1;CYC1;COX5B;COX5A;COX6B1
16	The citric acid (TCA) cycle and respiratory electron transport Homo sapiens R-HSA-1428517	0.0000000	0.0000000	NDUFB9;COX7B;NDUFB7;NDUFS8;NDUFB11;NDUFA3;NDUFB3;UQCRFS1;CYC1;COX5B;COX5A;COX6B1
16	Complex I biogenesis Homo sapiens R-HSA-6799198	0.0000000	0.0000000	NDUFB9;NDUFB7;NDUFS8;NDUFB11;NDUFA3;NDUFB3
16	Metabolism Homo sapiens R-HSA-1430728	0.0000002	0.0000012	NDUFB9;COX7B;NDUFB7;NDUFB11;NDUFA3;NDUFB3;COX5B;COX5A;PTGS1;COX6B1;NDUFS8;UQCRFS1;CYC1
16	TP53 Regulates Metabolic Genes Homo sapiens R-HSA-5628897	0.0000040	0.0000235	COX7B;COX5B;COX5A;COX6B1
16	Transcriptional Regulation by TP53 Homo sapiens R-HSA-3700989	0.0009950	0.0049748	COX7B;COX5B;COX5A;COX6B1
16	Generic Transcription Pathway Homo sapiens R-HSA-212436	0.0197901	0.0629685	COX7B;COX5B;COX5A;COX6B1
16	Gene Expression Homo sapiens R-HSA-74160	0.1576757	0.2759326	COX7B;COX5B;COX5A;COX6B1
17	microtubule-based movement (GO:0007018)	0.0000000	0.0000000	KIF14;KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF9;KIF18B;RACGAP1;KIFC1;KIF26B;KIF2C;KIF1A;KIF20A
17	microtubule-based process (GO:0007017)	0.0000000	0.0000000	PLK4;KIF14;KIF12;KIF23;KIF11;KIF6;KNSTRN;KIF15;CENPE;KIF18A;KIF9;KIF18B;RACGAP1;KIFC1;KIF26B;KIF2C;KIF1A;KIF20A
17	ATP catabolic process (GO:0006200)	0.0000000	0.0000000	KIF14;KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF9;KIF18B;KIFC1;KIF2C;KIF1A;KIF20A
17	purine ribonucleoside monophosphate catabolic process (GO:0009169)	0.0000000	0.0000000	KIF14;KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF9;KIF18B;KIFC1;KIF2C;KIF1A;KIF20A
17	ribonucleoside monophosphate catabolic process (GO:0009158)	0.0000000	0.0000000	KIF14;KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF9;KIF18B;KIFC1;KIF2C;KIF1A;KIF20A
17	purine nucleoside monophosphate catabolic process (GO:0009128)	0.0000000	0.0000000	KIF14;KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF9;KIF18B;KIFC1;KIF2C;KIF1A;KIF20A
17	nucleoside monophosphate catabolic process (GO:0009125)	0.0000000	0.0000000	KIF14;KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF9;KIF18B;KIFC1;KIF2C;KIF1A;KIF20A
17	ATP metabolic process (GO:0046034)	0.0000000	0.0000000	KIF14;KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF9;KIF18B;KIFC1;KIF2C;KIF1A;KIF20A
17	purine ribonucleoside monophosphate metabolic process (GO:0009167)	0.0000000	0.0000000	KIF14;KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF9;KIF18B;KIFC1;KIF2C;KIF1A;KIF20A
17	purine nucleoside monophosphate metabolic process (GO:0009126)	0.0000000	0.0000000	KIF14;KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF9;KIF18B;KIFC1;KIF2C;KIF1A;KIF20A
17	mitotic cell cycle (GO:0000278)	0.0000000	0.0000000	PLK4;BUB1B;NCAPG;KIF23;SMC4;NCAPH;CENPE;CENPF;KIF18A;KIF18B;MCM4;KIF2C;NCAPD2;KIF20A
17	ribonucleoside monophosphate metabolic process (GO:0009161)	0.0000000	0.0000000	KIF14;KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF9;KIF18B;KIFC1;KIF2C;KIF1A;KIF20A
17	nucleoside monophosphate metabolic process (GO:0009123)	0.0000000	0.0000000	KIF14;KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF9;KIF18B;KIFC1;KIF2C;KIF1A;KIF20A
17	chromosome organization (GO:0051276)	0.0000000	0.0000000	CENPE;CENPF;KIF18B;KIFC1;NCAPG;NCAPD2;TRIP13;SMC4;KNSTRN;NCAPH;REC8
17	chromosome segregation (GO:0007059)	0.0000000	0.0000000	CENPF;KIF18B;KIFC1;KIF2C;KIF11;SMC4;KNSTRN
17	antigen processing and presentation of exogenous peptide antigen via MHC class II (GO:0019886)	0.0000000	0.0000000	CENPE;KIF18A;RACGAP1;KIF23;KIF2C;KIF11;KIF15
17	antigen processing and presentation of peptide antigen via MHC class II (GO:0002495)	0.0000000	0.0000000	CENPE;KIF18A;RACGAP1;KIF23;KIF2C;KIF11;KIF15
17	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II (GO:0002504)	0.0000000	0.0000000	CENPE;KIF18A;RACGAP1;KIF23;KIF2C;KIF11;KIF15
17	regulation of chromosome segregation (GO:0051983)	0.0000000	0.0000000	CENPF;RACGAP1;BUB1B;KIF2C;ECT2;KNSTRN
17	mitotic chromosome condensation (GO:0007076)	0.0000000	0.0000001	NCAPG;NCAPD2;SMC4;NCAPH
17	antigen processing and presentation of exogenous peptide antigen (GO:0002478)	0.0000000	0.0000004	CENPE;KIF18A;RACGAP1;KIF23;KIF2C;KIF11;KIF15
17	antigen processing and presentation of exogenous antigen (GO:0019884)	0.0000000	0.0000004	CENPE;KIF18A;RACGAP1;KIF23;KIF2C;KIF11;KIF15
17	antigen processing and presentation of peptide antigen (GO:0048002)	0.0000000	0.0000006	CENPE;KIF18A;RACGAP1;KIF23;KIF2C;KIF11;KIF15
17	mitotic sister chromatid segregation (GO:0000070)	0.0000000	0.0000007	KIF18B;KIFC1;SMC4;KNSTRN
17	nuclear division (GO:0000280)	0.0000000	0.0000007	CENPF;BUB1B;KIF2C;KIF11;TRIP13;MKI67;REC8;KIF15
17	sister chromatid segregation (GO:0000819)	0.0000001	0.0000011	KIF18B;KIFC1;SMC4;KNSTRN
17	organelle fission (GO:0048285)	0.0000001	0.0000013	CENPF;BUB1B;KIF2C;KIF11;TRIP13;MKI67;REC8;KIF15
17	coagulation (GO:0050817)	0.0000001	0.0000015	CENPE;KIF18A;KIF9;RACGAP1;KIFC1;KIF23;KIF2C;KIF11;KIF15
17	blood coagulation (GO:0007596)	0.0000001	0.0000015	CENPE;KIF18A;KIF9;RACGAP1;KIFC1;KIF23;KIF2C;KIF11;KIF15
17	hemostasis (GO:0007599)	0.0000001	0.0000016	CENPE;KIF18A;KIF9;RACGAP1;KIFC1;KIF23;KIF2C;KIF11;KIF15
17	antigen processing and presentation (GO:0019882)	0.0000001	0.0000016	CENPE;KIF18A;RACGAP1;KIF23;KIF2C;KIF11;KIF15
17	regulation of cell division (GO:0051302)	0.0000002	0.0000020	CENPE;CENPF;KIF18B;RACGAP1;BUB1B;KIF23;ECT2
17	chromosome condensation (GO:0030261)	0.0000002	0.0000023	NCAPG;NCAPD2;SMC4;NCAPH
17	microtubule cytoskeleton organization (GO:0000226)	0.0000002	0.0000026	KIF18A;KIF18B;KIFC1;KIF2C;KIF11;KIF20A;KNSTRN
17	microtubule depolymerization (GO:0007019)	0.0000003	0.0000032	KIF18A;KIF18B;KIF2C
17	DNA packaging (GO:0006323)	0.0000005	0.0000053	NCAPG;NCAPD2;SMC4;NCAPH
17	regulation of attachment of spindle microtubules to kinetochore (GO:0051988)	0.0000009	0.0000090	RACGAP1;ECT2;KNSTRN
17	DNA conformation change (GO:0071103)	0.0000009	0.0000090	NCAPG;MCM4;NCAPD2;SMC4;NCAPH
17	kinetochore organization (GO:0051383)	0.0000015	0.0000147	CENPE;CENPF;SMC4
17	microtubule polymerization or depolymerization (GO:0031109)	0.0000019	0.0000183	KIF18A;KIF18B;KIF2C
17	metaphase plate congression (GO:0051310)	0.0000036	0.0000332	CENPE;CENPF;KIF18A
17	protein depolymerization (GO:0051261)	0.0000060	0.0000541	KIF18A;KIF18B;KIF2C
17	establishment of chromosome localization (GO:0051303)	0.0000106	0.0000933	CENPE;CENPF;KIF18A
17	cytokinesis (GO:0000910)	0.0000121	0.0001042	RACGAP1;KIF23;KIF20A;ECT2
17	regulation of cell cycle process (GO:0010564)	0.0000203	0.0001716	PLK4;CENPE;CENPF;RACGAP1;BUB1B;KIF23;ECT2
17	positive regulation of cytokinesis (GO:0032467)	0.0000210	0.0001737	RACGAP1;KIF23;ECT2
17	regulation of microtubule cytoskeleton organization (GO:0070507)	0.0000306	0.0002478	PLK4;RACGAP1;ECT2;KNSTRN
17	mitotic nuclear division (GO:0007067)	0.0000664	0.0005229	CENPF;BUB1B;KIF2C;KIF11;KIF15
17	regulation of mitotic metaphase/anaphase transition (GO:0030071)	0.0000674	0.0005229	CENPE;CENPF;BUB1B
17	regulation of microtubule-based process (GO:0032886)	0.0000711	0.0005376	PLK4;RACGAP1;ECT2;KNSTRN
17	regulation of metaphase/anaphase transition of cell cycle (GO:1902099)	0.0000721	0.0005376	CENPE;CENPF;BUB1B
17	regulation of cytokinesis (GO:0032465)	0.0000876	0.0006403	RACGAP1;KIF23;ECT2
17	organelle assembly (GO:0070925)	0.0001326	0.0009507	PLK4;CENPE;CENPF;KIFC1;KIF11
17	meiotic nuclear division (GO:0007126)	0.0002069	0.0014296	TRIP13;MKI67;REC8
17	spindle organization (GO:0007051)	0.0003180	0.0021200	KIFC1;KIF11;KNSTRN
17	meiotic cell cycle process (GO:1903046)	0.0006218	0.0039382	TRIP13;SMC4;REC8
17	positive regulation of cell cycle process (GO:0090068)	0.0006367	0.0039663	PLK4;RACGAP1;KIF23;ECT2
17	regulation of mitosis (GO:0007088)	0.0010669	0.0062745	CENPE;CENPF;BUB1B
17	cellular protein complex disassembly (GO:0043624)	0.0010946	0.0062745	KIF18A;KIF18B;KIF2C
17	cellular protein complex assembly (GO:0043623)	0.0011192	0.0062745	CENPE;CENPF;RACGAP1;KIF23
17	double-strand break repair (GO:0006302)	0.0011228	0.0062745	TONSL;TRIP13;REC8
17	regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032434)	0.0011806	0.0065018	CENPE;CENPF;BUB1B
17	positive regulation of cell division (GO:0051781)	0.0013017	0.0070663	RACGAP1;KIF23;ECT2
17	mitotic cell cycle phase transition (GO:0044772)	0.0014963	0.0078927	PLK4;CENPF;BUB1B;MCM4
17	positive regulation of cell cycle (GO:0045787)	0.0015162	0.0078927	PLK4;RACGAP1;KIF23;ECT2
17	cell cycle phase transition (GO:0044770)	0.0015566	0.0079933	PLK4;CENPF;BUB1B;MCM4
17	protein complex disassembly (GO:0043241)	0.0017111	0.0081275	KIF18A;KIF18B;KIF2C
17	regulation of proteasomal protein catabolic process (GO:0061136)	0.0018246	0.0084554	CENPE;CENPF;BUB1B
17	regulation of nuclear division (GO:0051783)	0.0019427	0.0085841	CENPE;CENPF;BUB1B
17	macromolecular complex disassembly (GO:0032984)	0.0021075	0.0092052	KIF18A;KIF18B;KIF2C
17	regulation of proteolysis involved in cellular protein catabolic process (GO:1903050)	0.0023706	0.0101216	CENPE;CENPF;BUB1B
17	regulation of cellular protein catabolic process (GO:1903362)	0.0027023	0.0109241	CENPE;CENPF;BUB1B
17	establishment of organelle localization (GO:0051656)	0.0033914	0.0134243	CENPE;CENPF;KIF18A
17	regulation of cytoskeleton organization (GO:0051493)	0.0034909	0.0135361	PLK4;RACGAP1;ECT2;KNSTRN
17	cellular component disassembly (GO:0022411)	0.0034909	0.0135361	KIF18A;KIF9;KIF18B;KIF2C
17	DNA recombination (GO:0006310)	0.0052168	0.0192463	TONSL;TRIP13;REC8
17	small GTPase mediated signal transduction (GO:0007264)	0.0077418	0.0265034	ARL11;RACGAP1;ECT2;RAB6B
17	regulation of mitotic cell cycle phase transition (GO:1901990)	0.0102765	0.0342550	CENPE;CENPF;BUB1B
17	regulation of small GTPase mediated signal transduction (GO:0051056)	0.0108390	0.0358158	RACGAP1;KIF14;ECT2
17	regulation of protein catabolic process (GO:0042176)	0.0113017	0.0370227	CENPE;CENPF;BUB1B
17	regulation of cell cycle phase transition (GO:1901987)	0.0117757	0.0382458	CENPE;CENPF;BUB1B
17	spermatogenesis (GO:0007283)	0.0253272	0.0677770	RACGAP1;TRIP13;REC8
17	male gamete generation (GO:0048232)	0.0255126	0.0677957	RACGAP1;TRIP13;REC8
17	gamete generation (GO:0007276)	0.0326791	0.0796031	RACGAP1;TRIP13;REC8
17	regulation of mitotic cell cycle (GO:0007346)	0.0328919	0.0796108	CENPE;CENPF;BUB1B
17	DNA repair (GO:0006281)	0.0355014	0.0827640	TONSL;TRIP13;REC8
17	negative regulation of cellular component organization (GO:0051129)	0.0530650	0.1084124	CENPF;KIF14;BUB1B
17	multicellular organismal reproductive process (GO:0048609)	0.0577957	0.1137947	RACGAP1;TRIP13;REC8
17	Kinesins Homo sapiens R-HSA-983189	0.0000000	0.0000000	KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF9;KIF18B;RACGAP1;KIFC1;KIF26B;KIF2C;KIF1A;KIF20A
17	Factors involved in megakaryocyte development and platelet production Homo sapiens R-HSA-983231	0.0000000	0.0000000	KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF9;KIF18B;RACGAP1;KIFC1;KIF26B;KIF2C;KIF1A;KIF20A
17	Golgi-to-ER retrograde transport Homo sapiens R-HSA-8856688	0.0000000	0.0000000	KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF18B;RACGAP1;KIF26B;KIF2C;KIF1A;KIF20A;RAB6B
17	COPI-dependent Golgi-to-ER retrograde traffic Homo sapiens R-HSA-6811434	0.0000000	0.0000000	KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF18B;RACGAP1;KIF26B;KIF2C;KIF1A;KIF20A
17	Intra-Golgi and retrograde Golgi-to-ER traffic Homo sapiens R-HSA-6811442	0.0000000	0.0000000	KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF18B;RACGAP1;KIF26B;KIF2C;KIF1A;KIF20A;RAB6B
17	Membrane Trafficking Homo sapiens R-HSA-199991	0.0000000	0.0000000	KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF18B;RACGAP1;KIF26B;KIF2C;KIF1A;KIF20A;RAB6B
17	Hemostasis Homo sapiens R-HSA-109582	0.0000000	0.0000000	KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF9;KIF18B;RACGAP1;KIFC1;KIF26B;KIF2C;KIF1A;KIF20A
17	Vesicle-mediated transport Homo sapiens R-HSA-5653656	0.0000000	0.0000000	KIF12;KIF23;KIF11;KIF6;KIF15;CENPE;KIF18A;KIF18B;RACGAP1;KIF26B;KIF2C;KIF1A;KIF20A;RAB6B
17	Mitotic Prometaphase Homo sapiens R-HSA-68877	0.0000000	0.0000000	CENPE;CENPF;KIF18A;BUB1B;NCAPG;KIF2C;NCAPD2;SMC4;NCAPH
17	Cell Cycle Homo sapiens R-HSA-1640170	0.0000000	0.0000000	PLK4;BUB1B;NCAPG;KIF23;SMC4;NCAPH;REC8;CENPE;CENPF;KIF18A;MCM4;KIF2C;NCAPD2;KIF20A
17	Cell Cycle, Mitotic Homo sapiens R-HSA-69278	0.0000000	0.0000000	PLK4;BUB1B;NCAPG;KIF23;SMC4;NCAPH;CENPE;CENPF;KIF18A;MCM4;KIF2C;NCAPD2;KIF20A
17	M Phase Homo sapiens R-HSA-68886	0.0000000	0.0000000	CENPE;CENPF;KIF18A;BUB1B;NCAPG;KIF23;KIF2C;NCAPD2;KIF20A;SMC4;NCAPH
17	MHC class II antigen presentation Homo sapiens R-HSA-2132295	0.0000000	0.0000000	CENPE;KIF18A;RACGAP1;KIF23;KIF2C;KIF11;KIF20A;KIF15
17	Condensation of Prometaphase Chromosomes Homo sapiens R-HSA-2514853	0.0000000	0.0000000	NCAPG;NCAPD2;SMC4;NCAPH
17	Signaling by Rho GTPases Homo sapiens R-HSA-194315	0.0000002	0.0000012	CENPE;CENPF;KIF18A;RACGAP1;KIF14;BUB1B;KIF2C;ECT2
17	Resolution of Sister Chromatid Cohesion Homo sapiens R-HSA-2500257	0.0000009	0.0000045	CENPE;CENPF;KIF18A;BUB1B;KIF2C
17	RHO GTPases Activate Formins Homo sapiens R-HSA-5663220	0.0000018	0.0000086	CENPE;CENPF;KIF18A;BUB1B;KIF2C
17	RHO GTPase Effectors Homo sapiens R-HSA-195258	0.0000057	0.0000258	CENPE;CENPF;KIF18A;KIF14;BUB1B;KIF2C
17	Separation of Sister Chromatids Homo sapiens R-HSA-2467813	0.0000101	0.0000430	CENPE;CENPF;KIF18A;BUB1B;KIF2C
17	Mitotic Anaphase Homo sapiens R-HSA-68882	0.0000139	0.0000550	CENPE;CENPF;KIF18A;BUB1B;KIF2C
17	Mitotic Metaphase and Anaphase Homo sapiens R-HSA-2555396	0.0000143	0.0000550	CENPE;CENPF;KIF18A;BUB1B;KIF2C
17	Adaptive Immune System Homo sapiens R-HSA-1280218	0.0000502	0.0001848	CENPE;KIF18A;RACGAP1;KIF23;KIF2C;KIF11;KIF20A;KIF15
17	Immune System Homo sapiens R-HSA-168256	0.0053840	0.0181710	CENPE;KIF18A;RACGAP1;KIF23;KIF2C;KIF11;KIF20A;KIF15
17	Signal Transduction Homo sapiens R-HSA-162582	0.0679021	0.1375017	CENPE;CENPF;KIF18A;RACGAP1;KIF14;BUB1B;KIF2C;ECT2
19	DNA replication-independent nucleosome organization (GO:0034724)	0.0000000	0.0000000	CENPU;CENPW;CENPK;HJURP;CENPN;CENPA;ASF1B
19	DNA replication-independent nucleosome assembly (GO:0006336)	0.0000000	0.0000000	CENPU;CENPW;CENPK;HJURP;CENPN;CENPA;ASF1B
19	CENP-A containing nucleosome assembly (GO:0034080)	0.0000000	0.0000000	CENPU;CENPW;CENPK;HJURP;CENPN;CENPA
19	chromatin remodeling at centromere (GO:0031055)	0.0000000	0.0000000	CENPU;CENPW;CENPK;HJURP;CENPN;CENPA
19	chromatin assembly or disassembly (GO:0006333)	0.0000000	0.0000000	CENPU;CENPW;CENPK;HJURP;CENPN;CENPA;ASF1B
19	histone exchange (GO:0043486)	0.0000000	0.0000000	CENPU;CENPW;CENPK;HJURP;CENPN;CENPA
19	nucleosome assembly (GO:0006334)	0.0000000	0.0000000	CENPU;CENPW;CENPK;HJURP;CENPN;CENPA;ASF1B
19	ATP-dependent chromatin remodeling (GO:0043044)	0.0000000	0.0000000	CENPU;CENPW;CENPK;HJURP;CENPN;CENPA
19	protein-DNA complex assembly (GO:0065004)	0.0000000	0.0000000	CENPU;CENPW;CENPK;HJURP;CENPN;CENPA;ASF1B
19	nucleosome organization (GO:0034728)	0.0000000	0.0000000	CENPU;CENPW;CENPK;HJURP;CENPN;CENPA;ASF1B
19	protein-DNA complex subunit organization (GO:0071824)	0.0000000	0.0000000	CENPU;CENPW;CENPK;HJURP;CENPN;CENPA;ASF1B
19	mitotic cell cycle (GO:0000278)	0.0000000	0.0000000	CENPU;CENPW;CENPK;NUF2;CENPL;CENPM;CENPN;CENPA;TUBB4A
19	chromatin remodeling (GO:0006338)	0.0000000	0.0000000	CENPU;CENPW;CENPK;HJURP;CENPN;CENPA
19	chromatin modification (GO:0016568)	0.0000004	0.0000032	CENPU;CENPW;CENPK;HJURP;CENPN;CENPA;ASF1B
19	chromosome segregation (GO:0007059)	0.0000021	0.0000177	CENPW;NUF2;HJURP;CENPN
19	chromosome organization (GO:0051276)	0.0012144	0.0086360	CENPW;CENPN;CENPA
19	mitotic nuclear division (GO:0007067)	0.0019344	0.0130317	CENPW;NUF2;CENPN
19	cellular protein complex assembly (GO:0043623)	0.0023243	0.0148753	CENPW;CENPA;TUBB4A
19	nuclear division (GO:0000280)	0.0035698	0.0217587	CENPW;NUF2;CENPN
19	organelle fission (GO:0048285)	0.0045510	0.0264786	CENPW;NUF2;CENPN
19	Deposition of new CENPA-containing nucleosomes at the centromere Homo sapiens R-HSA-606279	0.0000000	0.0000000	CENPU;CENPW;CENPK;HJURP;CENPL;CENPM;CENPN;CENPA
19	Nucleosome assembly Homo sapiens R-HSA-774815	0.0000000	0.0000000	CENPU;CENPW;CENPK;HJURP;CENPL;CENPM;CENPN;CENPA
19	Chromosome Maintenance Homo sapiens R-HSA-73886	0.0000000	0.0000000	CENPU;CENPW;CENPK;HJURP;CENPL;CENPM;CENPN;CENPA
19	Resolution of Sister Chromatid Cohesion Homo sapiens R-HSA-2500257	0.0000000	0.0000000	CENPU;CENPK;NUF2;CENPL;CENPM;CENPN;CENPA
19	Mitotic Prometaphase Homo sapiens R-HSA-68877	0.0000000	0.0000000	CENPU;CENPK;NUF2;CENPL;CENPM;CENPN;CENPA
19	RHO GTPases Activate Formins Homo sapiens R-HSA-5663220	0.0000000	0.0000000	CENPU;CENPK;NUF2;CENPL;CENPM;CENPN;CENPA
19	Cell Cycle Homo sapiens R-HSA-1640170	0.0000000	0.0000000	CENPU;CENPW;CENPK;NUF2;HJURP;CENPL;CENPM;CENPN;CENPA;TUBB4A
19	Separation of Sister Chromatids Homo sapiens R-HSA-2467813	0.0000000	0.0000000	CENPU;CENPK;NUF2;CENPL;CENPM;CENPN;CENPA
19	Mitotic Anaphase Homo sapiens R-HSA-68882	0.0000000	0.0000000	CENPU;CENPK;NUF2;CENPL;CENPM;CENPN;CENPA
19	Mitotic Metaphase and Anaphase Homo sapiens R-HSA-2555396	0.0000000	0.0000000	CENPU;CENPK;NUF2;CENPL;CENPM;CENPN;CENPA
19	RHO GTPase Effectors Homo sapiens R-HSA-195258	0.0000000	0.0000000	CENPU;CENPK;NUF2;CENPL;CENPM;CENPN;CENPA
19	M Phase Homo sapiens R-HSA-68886	0.0000000	0.0000000	CENPU;CENPK;NUF2;CENPL;CENPM;CENPN;CENPA
19	Cell Cycle, Mitotic Homo sapiens R-HSA-69278	0.0000000	0.0000000	CENPU;CENPK;NUF2;CENPL;CENPM;CENPN;CENPA;TUBB4A
19	Signaling by Rho GTPases Homo sapiens R-HSA-194315	0.0000001	0.0000002	CENPU;CENPK;NUF2;CENPL;CENPM;CENPN;CENPA
19	Signal Transduction Homo sapiens R-HSA-162582	0.0103621	0.0214862	CENPU;CENPK;NUF2;CENPL;CENPM;CENPN;CENPA
20	mitotic cell cycle (GO:0000278)	0.0000000	0.0000000	TOP2A;GINS1;GINS2;BORA;GINS4;PLK1;MCM10;CCNB1;ORC6;ORC1;PSMB3;BIRC5;MCM2
20	cell cycle phase transition (GO:0044770)	0.0000000	0.0000000	CCNB1;ORC6;BORA;MELK;ORC1;PSMB3;PLK1;TIMELESS;BIRC5;MCM10;MCM2
20	mitotic cell cycle phase transition (GO:0044772)	0.0000000	0.0000001	CCNB1;ORC6;BORA;MELK;ORC1;PSMB3;PLK1;BIRC5;MCM10;MCM2
20	DNA replication (GO:0006260)	0.0000000	0.0000007	GINS2;ORC6;ORC1;GINS3;GINS4;MCM10;CLSPN;MCM2
20	regulation of mitotic cell cycle (GO:0007346)	0.0000001	0.0000133	TOP2A;CCNB1;BORA;PSMB3;PLK1;BIRC5;CLSPN;BRCA2;GTSE1
20	regulation of cell cycle process (GO:0010564)	0.0000007	0.0000515	TOP2A;CCNB1;BORA;PSMB3;PLK1;BIRC5;CLSPN;BRCA2;GTSE1
20	DNA strand elongation involved in DNA replication (GO:0006271)	0.0000007	0.0000515	GINS1;GINS2;GINS4;MCM2
20	cell cycle G1/S phase transition (GO:0044843)	0.0000008	0.0000515	CCNB1;ORC6;ORC1;PSMB3;MCM10;MCM2
20	G1/S transition of mitotic cell cycle (GO:0000082)	0.0000008	0.0000515	CCNB1;ORC6;ORC1;PSMB3;MCM10;MCM2
20	DNA strand elongation (GO:0022616)	0.0000009	0.0000515	GINS1;GINS2;GINS4;MCM2
20	nuclear division (GO:0000280)	0.0000031	0.0001527	ASPM;BORA;PLK1;PBK;TIMELESS;BIRC5;BRCA2
20	negative regulation of mitotic cell cycle phase transition (GO:1901991)	0.0000033	0.0001527	TOP2A;CCNB1;PSMB3;PLK1;CLSPN;GTSE1
20	negative regulation of cell cycle phase transition (GO:1901988)	0.0000042	0.0001784	TOP2A;CCNB1;PSMB3;PLK1;CLSPN;GTSE1
20	organelle fission (GO:0048285)	0.0000055	0.0002180	ASPM;BORA;PLK1;PBK;TIMELESS;BIRC5;BRCA2
20	negative regulation of mitotic cell cycle (GO:0045930)	0.0000070	0.0002603	TOP2A;CCNB1;PSMB3;PLK1;CLSPN;GTSE1
20	G2/M transition of mitotic cell cycle (GO:0000086)	0.0000117	0.0003656	CCNB1;BORA;MELK;PLK1;BIRC5
20	cell cycle G2/M phase transition (GO:0044839)	0.0000117	0.0003656	CCNB1;BORA;MELK;PLK1;BIRC5
20	mitotic nuclear division (GO:0007067)	0.0000118	0.0003656	ASPM;BORA;PLK1;PBK;TIMELESS;BIRC5
20	regulation of mitotic cell cycle phase transition (GO:1901990)	0.0000152	0.0004465	TOP2A;CCNB1;PSMB3;PLK1;CLSPN;GTSE1
20	negative regulation of cell cycle process (GO:0010948)	0.0000163	0.0004537	TOP2A;CCNB1;PSMB3;PLK1;CLSPN;GTSE1
20	regulation of cell cycle phase transition (GO:1901987)	0.0000202	0.0005204	TOP2A;CCNB1;PSMB3;PLK1;CLSPN;GTSE1
20	cell cycle checkpoint (GO:0000075)	0.0000205	0.0005204	TOP2A;CCNB1;PLK1;BIRC5;CLSPN
20	positive regulation of cell cycle (GO:0045787)	0.0000270	0.0006562	CCNB1;PSMB3;PLK1;BIRC5;BRCA2;GTSE1
20	positive regulation of mitotic cell cycle (GO:0045931)	0.0000702	0.0015658	CCNB1;PLK1;BIRC5;BRCA2
20	mitotic cell cycle checkpoint (GO:0007093)	0.0000702	0.0015658	TOP2A;CCNB1;PLK1;CLSPN
20	spindle checkpoint (GO:0031577)	0.0000932	0.0020004	CCNB1;PLK1;BIRC5
20	regulation of cell division (GO:0051302)	0.0001407	0.0028042	ASPM;BORA;PLK1;BIRC5;BRCA2
20	cell division (GO:0051301)	0.0001780	0.0034245	TOP2A;ASPM;CCNB1;BIRC5
20	negative regulation of cell cycle (GO:0045786)	0.0002965	0.0050128	TOP2A;CCNB1;PSMB3;PLK1;CLSPN;GTSE1
20	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)	0.0004979	0.0079373	CCNB1;PSMB3;PLK1
20	nucleotide-excision repair (GO:0006289)	0.0005612	0.0086980	NEIL3;POLR2F;BRCA2
20	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)	0.0006294	0.0092421	CCNB1;PSMB3;PLK1
20	cytokinesis (GO:0000910)	0.0006533	0.0093466	PLK1;BIRC5;BRCA2
20	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031145)	0.0007283	0.0101599	CCNB1;PSMB3;PLK1
20	DNA integrity checkpoint (GO:0031570)	0.0008366	0.0113862	TOP2A;PLK1;CLSPN
20	positive regulation of ubiquitin-protein transferase activity (GO:0051443)	0.0008652	0.0114949	CCNB1;PSMB3;PLK1
20	chromosome segregation (GO:0007059)	0.0009242	0.0119935	TOP2A;PLK1;BIRC5
20	DNA damage response, signal transduction by p53 class mediator (GO:0030330)	0.0009857	0.0125010	PSMB3;BRCA2;GTSE1
20	positive regulation of ligase activity (GO:0051351)	0.0010175	0.0126164	CCNB1;PSMB3;PLK1
20	meiotic cell cycle process (GO:1903046)	0.0010498	0.0127345	TOP2A;PLK1;BRCA2
20	positive regulation of cell cycle process (GO:0090068)	0.0012562	0.0140191	PSMB3;PLK1;BIRC5;GTSE1
20	regulation of ubiquitin-protein transferase activity (GO:0051438)	0.0014095	0.0154218	CCNB1;PSMB3;PLK1
20	signal transduction in response to DNA damage (GO:0042770)	0.0015307	0.0164259	PSMB3;BRCA2;GTSE1
20	regulation of ligase activity (GO:0051340)	0.0016151	0.0170038	CCNB1;PSMB3;PLK1
20	DNA repair (GO:0006281)	0.0016616	0.0171704	NEIL3;UHRF1;POLR2F;CLSPN;BRCA2
20	regulation of mitosis (GO:0007088)	0.0017923	0.0181840	BORA;PLK1;BIRC5
20	signal transduction by p53 class mediator (GO:0072331)	0.0028598	0.0266616	PSMB3;BRCA2;GTSE1
20	regulation of nuclear division (GO:0051783)	0.0032419	0.0287141	BORA;PLK1;BIRC5
20	positive regulation of protein ubiquitination (GO:0031398)	0.0037982	0.0326060	CCNB1;PSMB3;PLK1
20	positive regulation of protein modification by small protein conjugation or removal (GO:1903322)	0.0047361	0.0400419	CCNB1;PSMB3;PLK1
20	proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161)	0.0096902	0.0667547	CCNB1;PSMB3;PLK1
20	proteasomal protein catabolic process (GO:0010498)	0.0106118	0.0672882	CCNB1;PSMB3;PLK1
20	regulation of protein ubiquitination (GO:0031396)	0.0106118	0.0672882	CCNB1;PSMB3;PLK1
20	cellular process involved in reproduction in multicellular organism (GO:0022412)	0.0129043	0.0782675	ASPM;CCNB1;BRCA2
20	regulation of protein modification by small protein conjugation or removal (GO:1903320)	0.0129043	0.0782675	CCNB1;PSMB3;PLK1
20	regulation of DNA metabolic process (GO:0051052)	0.0192193	0.0983885	TOP2A;CCNB1;BRCA2
20	protein catabolic process (GO:0030163)	0.0199879	0.1004798	CCNB1;PSMB3;PLK1
20	histone modification (GO:0016570)	0.0249550	0.1106289	UHRF1;BRCA2;HDAC9
20	covalent chromatin modification (GO:0016569)	0.0256187	0.1125608	UHRF1;BRCA2;HDAC9
20	RNA splicing (GO:0008380)	0.0295595	0.1183449	ESRP2;ESRP1;POLR2F
20	positive regulation of organelle organization (GO:0010638)	0.0364434	0.1309456	CCNB1;PLK1;BIRC5
20	cellular component disassembly (GO:0022411)	0.0391859	0.1341456	CCNB1;PLK1;CLSPN
20	spermatogenesis (GO:0007283)	0.0400288	0.1355061	ASPM;CCNB1;BRCA2
20	male gamete generation (GO:0048232)	0.0403118	0.1355061	ASPM;CCNB1;BRCA2
20	ubiquitin-dependent protein catabolic process (GO:0006511)	0.0405959	0.1356438	CCNB1;PSMB3;PLK1
20	modification-dependent protein catabolic process (GO:0019941)	0.0431986	0.1396676	CCNB1;PSMB3;PLK1
20	modification-dependent macromolecule catabolic process (GO:0043632)	0.0443818	0.1399156	CCNB1;PSMB3;PLK1
20	gamete generation (GO:0007276)	0.0511786	0.1496872	ASPM;CCNB1;BRCA2
20	proteolysis involved in cellular protein catabolic process (GO:0051603)	0.0514991	0.1496872	CCNB1;PSMB3;PLK1
20	mRNA processing (GO:0006397)	0.0534425	0.1496872	ESRP2;ESRP1;POLR2F
20	negative regulation of protein modification process (GO:0031400)	0.0567600	0.1522696	CCNB1;PSMB3;PLK1
20	microtubule-based process (GO:0007017)	0.0672892	0.1639623	PLK1;BIRC5;GTSE1
20	chromatin modification (GO:0016568)	0.0818186	0.1797431	UHRF1;BRCA2;HDAC9
20	multicellular organismal reproductive process (GO:0048609)	0.0883154	0.1835476	ASPM;CCNB1;BRCA2
20	Cell cycle Homo sapiens hsa04110	0.0000067	0.0001953	CCNB1;ORC6;ORC1;PLK1;MCM2
20	Pathways in cancer Homo sapiens hsa05200	0.0534425	0.2163984	LPAR5;BIRC5;BRCA2
20	Cell Cycle Homo sapiens R-HSA-1640170	0.0000000	0.0000000	TOP2A;GINS1;GINS2;BORA;GINS3;GINS4;PLK1;MCM10;HMMR;BRCA2;CCNB1;ORC6;ORC1;PSMB3;BIRC5;CLSPN;GTSE1;MCM2
20	Cell Cycle, Mitotic Homo sapiens R-HSA-69278	0.0000000	0.0000000	TOP2A;GINS1;GINS2;BORA;GINS3;GINS4;PLK1;MCM10;HMMR;CCNB1;ORC6;ORC1;PSMB3;BIRC5;GTSE1;MCM2
20	DNA Replication Homo sapiens R-HSA-69306	0.0000000	0.0000000	GINS1;GINS2;ORC6;ORC1;PSMB3;GINS3;GINS4;MCM10;MCM2
20	Unwinding of DNA Homo sapiens R-HSA-176974	0.0000000	0.0000000	GINS1;GINS2;GINS3;GINS4;MCM2
20	Synthesis of DNA Homo sapiens R-HSA-69239	0.0000000	0.0000000	GINS1;GINS2;ORC6;ORC1;PSMB3;GINS3;GINS4;MCM2
20	S Phase Homo sapiens R-HSA-69242	0.0000000	0.0000000	GINS1;GINS2;ORC6;ORC1;PSMB3;GINS3;GINS4;MCM2
20	G2/M Checkpoints Homo sapiens R-HSA-69481	0.0000000	0.0000000	CCNB1;ORC6;ORC1;PSMB3;MCM10;CLSPN;GTSE1;MCM2
20	Cell Cycle Checkpoints Homo sapiens R-HSA-69620	0.0000000	0.0000002	CCNB1;ORC6;ORC1;PSMB3;MCM10;CLSPN;GTSE1;MCM2
20	DNA strand elongation Homo sapiens R-HSA-69190	0.0000000	0.0000003	GINS1;GINS2;GINS3;GINS4;MCM2
20	Activation of ATR in response to replication stress Homo sapiens R-HSA-176187	0.0000000	0.0000005	ORC6;ORC1;MCM10;CLSPN;MCM2
20	Mitotic G1-G1/S phases Homo sapiens R-HSA-453279	0.0000000	0.0000005	TOP2A;CCNB1;ORC6;ORC1;PSMB3;MCM10;MCM2
20	G1/S Transition Homo sapiens R-HSA-69206	0.0000001	0.0000039	CCNB1;ORC6;ORC1;PSMB3;MCM10;MCM2
20	Removal of licensing factors from origins Homo sapiens R-HSA-69300	0.0000005	0.0000117	ORC6;ORC1;PSMB3;MCM10;MCM2
20	Activation of the pre-replicative complex Homo sapiens R-HSA-68962	0.0000005	0.0000117	ORC6;ORC1;MCM10;MCM2
20	Regulation of DNA replication Homo sapiens R-HSA-69304	0.0000006	0.0000125	ORC6;ORC1;PSMB3;MCM10;MCM2
20	DNA Replication Pre-Initiation Homo sapiens R-HSA-69002	0.0000009	0.0000172	ORC6;ORC1;PSMB3;MCM10;MCM2
20	M/G1 Transition Homo sapiens R-HSA-68874	0.0000009	0.0000172	ORC6;ORC1;PSMB3;MCM10;MCM2
20	E2F-enabled inhibition of pre-replication complex formation Homo sapiens R-HSA-113507	0.0000011	0.0000205	CCNB1;ORC6;ORC1
20	G2/M Transition Homo sapiens R-HSA-69275	0.0000018	0.0000318	CCNB1;BORA;PSMB3;PLK1;HMMR;GTSE1
20	Mitotic G2-G2/M phases Homo sapiens R-HSA-453274	0.0000019	0.0000322	CCNB1;BORA;PSMB3;PLK1;HMMR;GTSE1
20	The role of GTSE1 in G2/M progression after G2 checkpoint Homo sapiens R-HSA-8852276	0.0000077	0.0001237	CCNB1;PSMB3;PLK1;GTSE1
20	Assembly of the pre-replicative complex Homo sapiens R-HSA-68867	0.0000129	0.0001965	ORC6;ORC1;PSMB3;MCM2
20	Switching of origins to a post-replicative state Homo sapiens R-HSA-69052	0.0000153	0.0002144	ORC6;ORC1;PSMB3;MCM2
20	Orc1 removal from chromatin Homo sapiens R-HSA-68949	0.0000153	0.0002144	ORC6;ORC1;PSMB3;MCM2
20	FGFR2 alternative splicing Homo sapiens R-HSA-6803529	0.0000233	0.0003125	ESRP2;ESRP1;POLR2F
20	E2F mediated regulation of DNA replication Homo sapiens R-HSA-113510	0.0000483	0.0006240	CCNB1;ORC6;ORC1
20	CDT1 association with the CDC6:ORC:origin complex Homo sapiens R-HSA-68827	0.0002630	0.0028509	ORC6;ORC1;PSMB3
20	Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins Homo sapiens R-HSA-176814	0.0005612	0.0055456	CCNB1;PSMB3;PLK1
20	Regulation of APC/C activators between G1/S and early anaphase Homo sapiens R-HSA-176408	0.0006533	0.0061377	CCNB1;PSMB3;PLK1
20	APC/C-mediated degradation of cell cycle proteins Homo sapiens R-HSA-174143	0.0008086	0.0067926	CCNB1;PSMB3;PLK1
20	Regulation of mitotic cell cycle Homo sapiens R-HSA-453276	0.0008086	0.0067926	CCNB1;PSMB3;PLK1
20	Regulation of PLK1 Activity at G2/M Transition Homo sapiens R-HSA-2565942	0.0008652	0.0069217	CCNB1;BORA;PLK1
20	Resolution of Sister Chromatid Cohesion Homo sapiens R-HSA-2500257	0.0012576	0.0096034	CCNB1;PLK1;BIRC5
20	Mitotic Prometaphase Homo sapiens R-HSA-68877	0.0015725	0.0114863	CCNB1;PLK1;BIRC5
20	HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) Homo sapiens R-HSA-5693567	0.0017923	0.0128132	TIMELESS;CLSPN;BRCA2
20	Homology Directed Repair Homo sapiens R-HSA-5693538	0.0020803	0.0145621	TIMELESS;CLSPN;BRCA2
20	M Phase Homo sapiens R-HSA-68886	0.0025805	0.0176952	CCNB1;PSMB3;PLK1;BIRC5
20	DNA Repair Homo sapiens R-HSA-73894	0.0032188	0.0216304	TIMELESS;POLR2F;CLSPN;BRCA2
20	DNA Double-Strand Break Repair Homo sapiens R-HSA-5693532	0.0037257	0.0240736	TIMELESS;CLSPN;BRCA2
20	Separation of Sister Chromatids Homo sapiens R-HSA-2467813	0.0050772	0.0315913	PSMB3;PLK1;BIRC5
20	Mitotic Anaphase Homo sapiens R-HSA-68882	0.0060903	0.0364761	PSMB3;PLK1;BIRC5
20	Mitotic Metaphase and Anaphase Homo sapiens R-HSA-2555396	0.0061879	0.0364761	PSMB3;PLK1;BIRC5
20	Signaling by FGFR2 Homo sapiens R-HSA-5654738	0.0073998	0.0428678	PSMB3;ESRP2;ESRP1;POLR2F
20	Signaling by FGFR Homo sapiens R-HSA-190236	0.0077600	0.0440611	PSMB3;ESRP2;ESRP1;POLR2F
20	Disease Homo sapiens R-HSA-1643685	0.0190547	0.0901742	MUC16;PSMB3;POLR2F;HDAC9;MUC4
20	Diseases of signal transduction Homo sapiens R-HSA-5663202	0.0238699	0.1028242	PSMB3;POLR2F;HDAC9
20	Post-translational protein modification Homo sapiens R-HSA-597592	0.0252196	0.1032445	TOP2A;MUC16;BIRC5;MUC4
20	Transcriptional Regulation by TP53 Homo sapiens R-HSA-3700989	0.0386291	0.1395633	CCNB1;POLR2F;BIRC5
20	Signal Transduction Homo sapiens R-HSA-162582	0.1528028	0.2336588	LPAR5;PSMB3;ESRP2;ESRP1;PLK1;POLR2F;BIRC5;HDAC9
20	Metabolism of proteins Homo sapiens R-HSA-392499	0.1983363	0.2765187	TOP2A;MUC16;BIRC5;MUC4
20	Generic Transcription Pathway Homo sapiens R-HSA-212436	0.2533669	0.3327388	CCNB1;POLR2F;BIRC5
20	Gene Expression Homo sapiens R-HSA-74160	0.2715095	0.3489151	CCNB1;UHRF1;PSMB3;POLR2F;BIRC5
20	CDK Regulation of DNA Replication Homo sapiens h mcmPathway	0.0000074	0.0001108	ORC6;ORC1;MCM2
22	cell chemotaxis (GO:0060326)	0.0000000	0.0000000	CX3CR1;CCR1;CXCL10;CXCL9;CCL8;SYK;CCL2;CXCL1;CCR5;CXCL14;PIK3CG;CXCL16
22	taxis (GO:0042330)	0.0000000	0.0000000	CX3CR1;CCR1;CXCL9;SYK;CXCL17;CXCL1;CXCL14;PIK3CG;CXCL16;CXCL10;CCL8;CCL2;CCR5
22	chemotaxis (GO:0006935)	0.0000000	0.0000000	CX3CR1;CCR1;CXCL9;SYK;CXCL17;CXCL1;CXCL14;PIK3CG;CXCL16;CXCL10;CCL8;CCL2;CCR5
22	leukocyte chemotaxis (GO:0030595)	0.0000000	0.0000000	CX3CR1;CCR1;CXCL10;SYK;CCL2;CCR5;PIK3CG;CXCL16
22	leukocyte migration (GO:0050900)	0.0000000	0.0000000	CX3CR1;CCR1;CD2;CXCL10;SYK;CCL2;CCR5;PIK3CG;CXCL16
22	cytokine-mediated signaling pathway (GO:0019221)	0.0000000	0.0000002	CX3CR1;CCR1;CXCL10;STAT1;CCL2;IL2RG;CCR5;IFIT2;IL27RA
22	chemokine-mediated signaling pathway (GO:0070098)	0.0000000	0.0000003	CX3CR1;CCR1;CXCL10;CCL2;CCR5
22	inflammatory response (GO:0006954)	0.0000000	0.0000004	CCR1;CXCL10;CXCL9;CCL8;IL23A;CCL2;CXCL1;CCR5;PIK3CG
22	lymphocyte chemotaxis (GO:0048247)	0.0000000	0.0000008	CXCL10;CCL2;PIK3CG;CXCL16
22	response to other organism (GO:0051707)	0.0000000	0.0000020	CXCL10;CXCL9;CCL8;SYK;STAT1;IL23A;CCL2;IFIT2;IL27RA
22	cellular response to cytokine stimulus (GO:0071345)	0.0000000	0.0000021	CX3CR1;CCR1;CXCL10;STAT1;CCL2;IL2RG;CCR5;IFIT2;IL27RA
22	cellular response to biotic stimulus (GO:0071216)	0.0000000	0.0000035	CX3CR1;CXCL10;SYK;STAT1;CCL2;CCR5
22	lymphocyte migration (GO:0072676)	0.0000001	0.0000064	CXCL10;CCL2;PIK3CG;CXCL16
22	regulation of calcium ion transport (GO:0051924)	0.0000002	0.0000140	CCR1;CXCL10;CXCL9;UBASH3B;CCL2;ATP2B2
22	positive regulation of calcium ion transport (GO:0051928)	0.0000003	0.0000160	CCR1;CXCL10;CXCL9;CCL2;ATP2B2
22	defense response to other organism (GO:0098542)	0.0000006	0.0000312	CXCL10;CXCL9;SYK;STAT1;IL23A;IFIT2;IL27RA
22	cellular response to lipopolysaccharide (GO:0071222)	0.0000007	0.0000364	CX3CR1;CXCL10;STAT1;CCL2;CCR5
22	cellular response to molecule of bacterial origin (GO:0071219)	0.0000009	0.0000448	CX3CR1;CXCL10;STAT1;CCL2;CCR5
22	T cell migration (GO:0072678)	0.0000012	0.0000568	CXCL10;CCL2;PIK3CG
22	positive regulation of leukocyte chemotaxis (GO:0002690)	0.0000016	0.0000729	CCR1;CXCL10;IL23A;CCL2
22	dendritic cell chemotaxis (GO:0002407)	0.0000019	0.0000788	CCR1;CCR5;PIK3CG
22	regulation of metal ion transport (GO:0010959)	0.0000020	0.0000788	CCR1;CXCL10;CXCL9;UBASH3B;CCL2;ATP2B2
22	response to virus (GO:0009615)	0.0000020	0.0000788	CXCL10;CXCL9;CCL8;STAT1;IL23A;IFIT2
22	cellular ion homeostasis (GO:0006873)	0.0000022	0.0000809	CCR1;SLC34A2;CCL8;CCL2;ATP2B2;CCR5;PIK3CG
22	cellular calcium ion homeostasis (GO:0006874)	0.0000026	0.0000929	CCR1;CCL8;CCL2;ATP2B2;CCR5;PIK3CG
22	negative regulation of angiogenesis (GO:0016525)	0.0000028	0.0000962	CX3CR1;CXCL10;STAT1;CCL2
22	defense response to virus (GO:0051607)	0.0000029	0.0000962	CXCL10;CXCL9;STAT1;IL23A;IFIT2
22	negative regulation of blood vessel morphogenesis (GO:2000181)	0.0000032	0.0000995	CX3CR1;CXCL10;STAT1;CCL2
22	cellular divalent inorganic cation homeostasis (GO:0072503)	0.0000032	0.0000995	CCR1;CCL8;CCL2;ATP2B2;CCR5;PIK3CG
22	calcium ion homeostasis (GO:0055074)	0.0000035	0.0001025	CCR1;CCL8;CCL2;ATP2B2;CCR5;PIK3CG
22	regulation of leukocyte chemotaxis (GO:0002688)	0.0000036	0.0001030	CCR1;CXCL10;IL23A;CCL2
22	positive regulation of cell migration (GO:0030335)	0.0000039	0.0001087	CCR1;TFAP2A;CXCL10;IL23A;CCL2;CXCL16
22	negative regulation of vasculature development (GO:1901343)	0.0000040	0.0001087	CX3CR1;CXCL10;STAT1;CCL2
22	dendritic cell migration (GO:0036336)	0.0000044	0.0001147	CCR1;CCR5;PIK3CG
22	positive regulation of cell motility (GO:2000147)	0.0000045	0.0001147	CCR1;TFAP2A;CXCL10;IL23A;CCL2;CXCL16
22	cellular chemical homeostasis (GO:0055082)	0.0000047	0.0001168	CCR1;SLC34A2;CCL8;CCL2;ATP2B2;CCR5;PIK3CG
22	divalent inorganic cation homeostasis (GO:0072507)	0.0000049	0.0001175	CCR1;CCL8;CCL2;ATP2B2;CCR5;PIK3CG
22	positive regulation of cellular component movement (GO:0051272)	0.0000054	0.0001262	CCR1;TFAP2A;CXCL10;IL23A;CCL2;CXCL16
22	myeloid leukocyte migration (GO:0097529)	0.0000056	0.0001279	CX3CR1;SYK;CCL2;PIK3CG
22	positive regulation of leukocyte migration (GO:0002687)	0.0000062	0.0001362	CCR1;CXCL10;IL23A;CCL2
22	positive regulation of locomotion (GO:0040017)	0.0000063	0.0001362	CCR1;TFAP2A;CXCL10;IL23A;CCL2;CXCL16
22	positive regulation of ion transport (GO:0043270)	0.0000092	0.0001950	CCR1;CXCL10;CXCL9;CCL2;ATP2B2
22	positive regulation of chemotaxis (GO:0050921)	0.0000110	0.0002275	CCR1;CXCL10;IL23A;CCL2
22	positive regulation of response to external stimulus (GO:0032103)	0.0000134	0.0002710	CCR1;CXCL10;IL23A;CCL2;PIK3CG
22	cellular metal ion homeostasis (GO:0006875)	0.0000167	0.0003298	CCR1;CCL8;CCL2;ATP2B2;CCR5;PIK3CG
22	myeloid cell activation involved in immune response (GO:0002275)	0.0000213	0.0004127	CX3CR1;SYK;PIK3CG
22	positive regulation of behavior (GO:0048520)	0.0000218	0.0004127	CCR1;CXCL10;IL23A;CCL2
22	regulation of leukocyte migration (GO:0002685)	0.0000243	0.0004465	CCR1;CXCL10;IL23A;CCL2
22	response to lipopolysaccharide (GO:0032496)	0.0000246	0.0004465	CX3CR1;CXCL10;STAT1;CCL2;CCR5
22	cellular cation homeostasis (GO:0030003)	0.0000254	0.0004523	CCR1;CCL8;CCL2;ATP2B2;CCR5;PIK3CG
22	response to molecule of bacterial origin (GO:0002237)	0.0000334	0.0005820	CX3CR1;CXCL10;STAT1;CCL2;CCR5
22	regulation of chemotaxis (GO:0050920)	0.0000342	0.0005855	CCR1;CXCL10;IL23A;CCL2
22	regulation of cell activation (GO:0050865)	0.0000390	0.0006555	CD2;UBASH3B;SYK;IL23A;CCL2;IL27RA
22	metal ion homeostasis (GO:0055065)	0.0000401	0.0006607	CCR1;CCL8;CCL2;ATP2B2;CCR5;PIK3CG
22	neutrophil chemotaxis (GO:0030593)	0.0000428	0.0006921	SYK;CCL2;PIK3CG
22	neutrophil migration (GO:1990266)	0.0000458	0.0007276	SYK;CCL2;PIK3CG
22	cation homeostasis (GO:0055080)	0.0000687	0.0010366	CCR1;CCL8;CCL2;ATP2B2;CCR5;PIK3CG
22	positive regulation of interferon-gamma production (GO:0032729)	0.0000708	0.0010498	CD2;IL23A;IL27RA
22	granulocyte chemotaxis (GO:0071621)	0.0000749	0.0010934	SYK;CCL2;PIK3CG
22	regulation of release of sequestered calcium ion into cytosol (GO:0051279)	0.0000838	0.0011647	CXCL10;CXCL9;UBASH3B
22	granulocyte migration (GO:0097530)	0.0000838	0.0011647	SYK;CCL2;PIK3CG
22	regulation of ion homeostasis (GO:2000021)	0.0001049	0.0014143	CXCL10;CXCL9;UBASH3B;CCR5
22	cellular defense response (GO:0006968)	0.0001087	0.0014436	CX3CR1;CXCL9;CCR5
22	regulation of homeostatic process (GO:0032844)	0.0001123	0.0014695	CXCL10;CXCL9;UBASH3B;SYK;CCR5
22	cellular response to lipid (GO:0071396)	0.0001140	0.0014699	CX3CR1;CXCL10;STAT1;CCL2;CCR5
22	regulation of behavior (GO:0050795)	0.0001209	0.0015372	CCR1;CXCL10;IL23A;CCL2
22	cytosolic calcium ion homeostasis (GO:0051480)	0.0001514	0.0018529	CCR1;ATP2B2;CCR5;PIK3CG
22	response to mechanical stimulus (GO:0009612)	0.0001514	0.0018529	CXCL10;STAT1;CCL2;ATP2B2
22	regulation of angiogenesis (GO:0045765)	0.0001616	0.0019437	CX3CR1;CXCL10;STAT1;CCL2
22	regulation of lymphocyte activation (GO:0051249)	0.0001720	0.0020408	CD2;SYK;IL23A;CCL2;IL27RA
22	regulation of calcium ion transport into cytosol (GO:0010522)	0.0001870	0.0021341	CXCL10;CXCL9;UBASH3B
22	regulation of vasculature development (GO:1901342)	0.0002333	0.0025949	CX3CR1;CXCL10;STAT1;CCL2
22	regulation of interferon-gamma production (GO:0032649)	0.0002462	0.0026684	CD2;IL23A;IL27RA
22	leukocyte activation (GO:0045321)	0.0002503	0.0026684	CX3CR1;CD2;SYK;IL23A;PIK3CG
22	response to bacterium (GO:0009617)	0.0002518	0.0026684	SYK;IL23A;CCL2;IL27RA
22	regulation of leukocyte differentiation (GO:1902105)	0.0002976	0.0030794	CCR1;CD2;SYK;IL23A
22	regulation of leukocyte activation (GO:0002694)	0.0003074	0.0031452	CD2;SYK;IL23A;CCL2;IL27RA
22	myeloid leukocyte activation (GO:0002274)	0.0003163	0.0031987	CX3CR1;SYK;PIK3CG
22	regulation of intracellular transport (GO:0032386)	0.0003222	0.0032177	CXCL10;CXCL9;UBASH3B;SYK;IL23A
22	calcium ion transport (GO:0006816)	0.0003254	0.0032177	CCR1;CCL8;ATP2B2;CCR5
22	positive regulation of intracellular transport (GO:0032388)	0.0003370	0.0032962	CXCL10;CXCL9;SYK;IL23A
22	secretion by cell (GO:0032940)	0.0004088	0.0039550	CCR1;CXCL10;CCL8;SYK;PIK3CG
22	divalent metal ion transport (GO:0070838)	0.0004483	0.0042198	CCR1;CCL8;ATP2B2;CCR5
22	regulation of T cell differentiation (GO:0045580)	0.0004504	0.0042198	CD2;SYK;IL23A
22	angiogenesis (GO:0001525)	0.0004630	0.0042920	SYK;CXCL17;CCL2;PIK3CG
22	divalent inorganic cation transport (GO:0072511)	0.0004779	0.0043095	CCR1;CCL8;ATP2B2;CCR5
22	response to interferon-gamma (GO:0034341)	0.0006166	0.0053797	STAT1;CCL2;CXCL16
22	regulation of T cell activation (GO:0050863)	0.0006566	0.0056190	CD2;SYK;IL23A;CCL2
22	response to tumor necrosis factor (GO:0034612)	0.0006678	0.0056491	STAT1;CCL2;CXCL16
22	cell activation involved in immune response (GO:0002263)	0.0006854	0.0056491	CX3CR1;SYK;PIK3CG
22	leukocyte activation involved in immune response (GO:0002366)	0.0006854	0.0056491	CX3CR1;SYK;PIK3CG
22	positive regulation of leukocyte activation (GO:0002696)	0.0006855	0.0056491	CD2;SYK;IL23A;CCL2
22	regulation of immune effector process (GO:0002697)	0.0007053	0.0057587	SYK;IL23A;CCL2;IL27RA
22	positive regulation of cell activation (GO:0050867)	0.0007884	0.0062167	CD2;SYK;IL23A;CCL2
22	positive regulation of leukocyte differentiation (GO:1902107)	0.0007977	0.0062167	CCR1;SYK;IL23A
22	regulation of cytokine production (GO:0001817)	0.0008060	0.0062167	CD2;SYK;IL23A;CCL2;IL27RA
22	response to alcohol (GO:0097305)	0.0008103	0.0062167	SLC34A2;CXCL10;CCL2;CCR5
22	regulation of leukocyte mediated immunity (GO:0002703)	0.0008376	0.0063711	SYK;IL23A;IL27RA
22	regulation of lymphocyte differentiation (GO:0045619)	0.0009210	0.0068883	CD2;SYK;IL23A
22	positive regulation of homeostatic process (GO:0032846)	0.0010558	0.0077661	CXCL10;CXCL9;SYK
22	positive regulation of immune effector process (GO:0002699)	0.0011277	0.0081597	SYK;IL23A;CCL2
22	positive regulation of cytokine production (GO:0001819)	0.0015579	0.0109175	CD2;SYK;IL23A;IL27RA
22	positive regulation of cytosolic calcium ion concentration (GO:0007204)	0.0016549	0.0115068	CCR1;CCR5;PIK3CG
22	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger (GO:0007187)	0.0016862	0.0116338	CCR1;GPR37;CCL2
22	regulation of response to wounding (GO:1903034)	0.0019354	0.0129508	UBASH3B;SYK;IL23A;PIK3CG
22	response to nutrient (GO:0007584)	0.0020202	0.0134178	CXCL10;STAT1;CCL2
22	response to wounding (GO:0009611)	0.0021645	0.0139596	CX3CR1;CCR1;CCL2
22	defense response to bacterium (GO:0042742)	0.0026354	0.0165179	SYK;IL23A;IL27RA
22	positive regulation of T cell activation (GO:0050870)	0.0030728	0.0189800	SYK;IL23A;CCL2
22	positive regulation of MAPK cascade (GO:0043410)	0.0030922	0.0189800	CCR1;GPR37;SYK;PIK3CG
22	T cell activation (GO:0042110)	0.0035025	0.0212056	CD2;IL23A;PIK3CG
22	positive regulation of protein transport (GO:0051222)	0.0053853	0.0304507	CD2;SYK;IL23A
22	exocytosis (GO:0006887)	0.0055155	0.0307075	CCR1;CCL8;PIK3CG
22	single organismal cell-cell adhesion (GO:0016337)	0.0056476	0.0310271	CD2;SYK;PIK3CG
22	coagulation (GO:0050817)	0.0058171	0.0314117	CD2;SYK;ATP2B2;PIK3CG
22	blood coagulation (GO:0007596)	0.0058171	0.0314117	CD2;SYK;ATP2B2;PIK3CG
22	hemostasis (GO:0007599)	0.0060801	0.0320196	CD2;SYK;ATP2B2;PIK3CG
22	positive regulation of lymphocyte activation (GO:0051251)	0.0061950	0.0324328	SYK;IL23A;CCL2
22	single organism cell adhesion (GO:0098602)	0.0073827	0.0363019	CD2;SYK;PIK3CG
22	response to nutrient levels (GO:0031667)	0.0101411	0.0465238	CXCL10;STAT1;CCL2
22	lymphocyte activation (GO:0046649)	0.0114117	0.0515741	CD2;IL23A;PIK3CG
22	response to extracellular stimulus (GO:0009991)	0.0123430	0.0515741	CXCL10;STAT1;CCL2
22	regulation of cell adhesion (GO:0030155)	0.0149181	0.0559270	UBASH3B;SYK;PIK3CG
22	response to steroid hormone (GO:0048545)	0.0191095	0.0609586	SLC34A2;CITED4;CCL2
22	regulation of protein transport (GO:0051223)	0.0204964	0.0626866	CD2;SYK;IL23A
22	organ morphogenesis (GO:0009887)	0.0243583	0.0669485	TFAP2A;SYK;CCL2
22	regulation of establishment of protein localization (GO:0070201)	0.0304924	0.0737129	CD2;SYK;IL23A
22	positive regulation of protein kinase activity (GO:0045860)	0.0330084	0.0766036	SYK;CCL2;PIK3CG
22	transcription from RNA polymerase II promoter (GO:0006366)	0.0356310	0.0779155	TFAP2A;TFAP2C;STAT1
22	positive regulation of kinase activity (GO:0033674)	0.0375692	0.0795149	SYK;CCL2;PIK3CG
22	Chemokine signaling pathway Homo sapiens hsa04062	0.0000000	0.0000000	CX3CR1;CCR1;CXCL9;STAT1;CCL4L2;CXCL1;CXCL14;PIK3CG;CXCL16;CXCL10;CCL8;CCL2;CCR5
22	Cytokine-cytokine receptor interaction Homo sapiens hsa04060	0.0000000	0.0000000	CX3CR1;CCR1;CXCL9;CCL4L2;CXCL1;IL2RG;CXCL14;CXCL16;CXCL10;CCL8;IL23A;CCL2;CCR5
22	Toll-like receptor signaling pathway Homo sapiens hsa04620	0.0000006	0.0000193	CXCL10;CXCL9;STAT1;CCL4L2;PIK3CG
22	Jak-STAT signaling pathway Homo sapiens hsa04630	0.0000042	0.0001039	STAT1;IL23A;IL2RG;PIK3CG;IL27RA
22	TNF signaling pathway Homo sapiens hsa04668	0.0000243	0.0004861	CXCL10;CCL2;CXCL1;PIK3CG
22	Inflammatory bowel disease (IBD) Homo sapiens hsa05321	0.0001380	0.0021167	STAT1;IL23A;IL2RG
22	Influenza A Homo sapiens hsa05164	0.0001482	0.0021167	CXCL10;STAT1;CCL2;PIK3CG
22	Rheumatoid arthritis Homo sapiens hsa05323	0.0003615	0.0045193	IL23A;CCL2;CXCL1
22	AGE-RAGE signaling pathway in diabetic complications Homo sapiens hsa04933	0.0005070	0.0056332	STAT1;CCL2;PIK3CG
22	Toxoplasmosis Homo sapiens hsa05145	0.0007977	0.0079769	STAT1;CCR5;PIK3CG
22	Osteoclast differentiation Homo sapiens hsa04380	0.0011034	0.0100214	SYK;STAT1;PIK3CG
22	Measles Homo sapiens hsa05162	0.0012026	0.0100214	STAT1;IL2RG;PIK3CG
22	Tuberculosis Homo sapiens hsa05152	0.0025940	0.0199537	SYK;STAT1;IL23A
22	Viral carcinogenesis Homo sapiens hsa05203	0.0038610	0.0257399	SYK;CCR5;PIK3CG
22	PI3K-Akt signaling pathway Homo sapiens hsa04151	0.0155153	0.0554119	SYK;IL2RG;PIK3CG
22	Chemokine receptors bind chemokines Homo sapiens R-HSA-380108	0.0000000	0.0000000	CX3CR1;CCR1;CXCL10;CXCL9;CCL2;CXCL1;CCR5;CXCL16
22	Peptide ligand-binding receptors Homo sapiens R-HSA-375276	0.0000000	0.0000000	CX3CR1;CCR1;CXCL10;CXCL9;GPR37;CCL2;CXCL1;CCR5;CXCL16
22	Class A/1 (Rhodopsin-like receptors) Homo sapiens R-HSA-373076	0.0000000	0.0000000	CX3CR1;CCR1;CXCL10;CXCL9;GPR37;CCL2;CXCL1;CCR5;CXCL16
22	GPCR ligand binding Homo sapiens R-HSA-500792	0.0000000	0.0000006	CX3CR1;CCR1;CXCL10;CXCL9;GPR37;CCL2;CXCL1;CCR5;CXCL16
22	G alpha (i) signalling events Homo sapiens R-HSA-418594	0.0000016	0.0000424	CCR1;CXCL10;CXCL9;CXCL1;CCR5;CXCL16
22	Signaling by GPCR Homo sapiens R-HSA-372790	0.0000020	0.0000441	CX3CR1;CCR1;CXCL10;CXCL9;GPR37;CCL2;CXCL1;IL2RG;CCR5;PIK3CG;CXCL16
22	Signal Transduction Homo sapiens R-HSA-162582	0.0000349	0.0006581	CX3CR1;CCR1;CXCL9;GPR37;SYK;STAT1;CXCL1;IL2RG;PIK3CG;CXCL16;CXCL10;CCL2;CCR5
22	GPVI-mediated activation cascade Homo sapiens R-HSA-114604	0.0000749	0.0012366	SYK;IL2RG;PIK3CG
22	GPCR downstream signaling Homo sapiens R-HSA-388396	0.0000949	0.0013924	CCR1;CXCL10;CXCL9;CXCL1;IL2RG;CCR5;PIK3CG;CXCL16
22	Signaling by Interleukins Homo sapiens R-HSA-449147	0.0003148	0.0039488	SYK;STAT1;IL23A;IL2RG;IL27RA
22	Cytokine Signaling in Immune system Homo sapiens R-HSA-1280215	0.0003291	0.0039488	SYK;STAT1;IL23A;IL2RG;IFIT2;IL27RA
22	Hemostasis Homo sapiens R-HSA-109582	0.0014751	0.0149781	CD2;SYK;ATP2B2;IL2RG;PIK3CG
22	Immune System Homo sapiens R-HSA-168256	0.0019820	0.0186872	CD200R1;SIGLEC14;SYK;STAT1;IL23A;IL2RG;IFIT2;IL27RA
22	Platelet activation, signaling and aggregation Homo sapiens R-HSA-76002	0.0069227	0.0507663	SYK;IL2RG;PIK3CG
22	DAP12 interactions Homo sapiens R-HSA-2172127	0.0177771	0.1014593	SIGLEC14;SYK;IL2RG
22	Innate Immune System Homo sapiens R-HSA-168249	0.1280526	0.2726282	SIGLEC14;SYK;IL2RG
23	DNA repair (GO:0006281)	0.0000000	0.0000001	EME1;CDCA5;UBE2T;FANCA;HMGA1;CDK1;FAAP24;HMGA2;RAD54L
23	nuclear division (GO:0000280)	0.0000006	0.0001816	CDCA5;FANCA;CDK1;HMGA2;RAD54L;FAM83D
23	organelle fission (GO:0048285)	0.0000011	0.0002008	CDCA5;FANCA;CDK1;HMGA2;RAD54L;FAM83D
23	chromosome organization (GO:0051276)	0.0000024	0.0003437	CDCA5;CDK1;CDCA8;HMGA2;RAD54L
23	DNA conformation change (GO:0071103)	0.0000039	0.0003950	CDCA5;HMGA1;CDK1;HMGA2
23	chromosome condensation (GO:0030261)	0.0000041	0.0003950	CDCA5;CDK1;HMGA2
23	DNA packaging (GO:0006323)	0.0000081	0.0006583	CDCA5;CDK1;HMGA2
23	cell aging (GO:0007569)	0.0000419	0.0026622	HMGA1;CDK1;HMGA2
23	negative regulation of mitotic cell cycle phase transition (GO:1901991)	0.0000526	0.0030079	RGCC;CDK1;CHMP4C;HMGA2
23	negative regulation of cell cycle phase transition (GO:1901988)	0.0000616	0.0032050	RGCC;CDK1;CHMP4C;HMGA2
23	negative regulation of cell cycle (GO:0045786)	0.0000874	0.0036540	RGCC;CDK1;CHMP4C;HMGA2;CDKN3
23	negative regulation of mitotic cell cycle (GO:0045930)	0.0000876	0.0036540	RGCC;CDK1;CHMP4C;HMGA2
23	mitotic nuclear division (GO:0007067)	0.0001248	0.0040435	CDCA5;CDK1;HMGA2;FAM83D
23	regulation of cell cycle process (GO:0010564)	0.0001479	0.0040435	RGCC;CDCA5;CDK1;CHMP4C;HMGA2
23	regulation of mitotic cell cycle phase transition (GO:1901990)	0.0001483	0.0040435	RGCC;CDK1;CHMP4C;HMGA2
23	negative regulation of cell cycle process (GO:0010948)	0.0001552	0.0040435	RGCC;CDK1;CHMP4C;HMGA2
23	regulation of cell cycle phase transition (GO:1901987)	0.0001800	0.0044763	RGCC;CDK1;CHMP4C;HMGA2
23	mitotic cell cycle checkpoint (GO:0007093)	0.0001902	0.0045340	CDK1;CHMP4C;HMGA2
23	cell cycle G1/S phase transition (GO:0044843)	0.0005961	0.0106547	CDCA5;CDK1;CDKN3
23	G1/S transition of mitotic cell cycle (GO:0000082)	0.0005961	0.0106547	CDCA5;CDK1;CDKN3
23	cell cycle checkpoint (GO:0000075)	0.0006429	0.0108153	CDK1;CHMP4C;HMGA2
23	regulation of mitotic cell cycle (GO:0007346)	0.0007960	0.0126474	RGCC;CDK1;CHMP4C;HMGA2
23	aging (GO:0007568)	0.0013957	0.0204701	HMGA1;CDK1;HMGA2
23	nucleic acid phosphodiester bond hydrolysis (GO:0090305)	0.0019669	0.0267878	EME1;HMGA1;HMGA2
23	regulation of DNA metabolic process (GO:0051052)	0.0029395	0.0357743	RGCC;CDK1;HMGA2
23	mitotic cell cycle phase transition (GO:0044772)	0.0033303	0.0384869	CDCA5;CDK1;CDKN3
23	positive regulation of cell cycle (GO:0045787)	0.0033642	0.0384869	RGCC;CDK1;HMGA2
23	cell cycle phase transition (GO:0044770)	0.0034328	0.0385007	CDCA5;CDK1;CDKN3
23	cellular component disassembly (GO:0022411)	0.0063930	0.0580444	HMGA1;CDK1;LMNB1
23	response to drug (GO:0042493)	0.0065966	0.0587234	SMAD1;CDK1;RAD54L
23	mitotic cell cycle (GO:0000278)	0.0094731	0.0662010	CDCA5;CDK1;CDCA8
23	cellular response to organonitrogen compound (GO:0071417)	0.0099259	0.0662010	CDK1;LAMTOR2;ATP6V0E2
23	regulation of protein serine/threonine kinase activity (GO:0071900)	0.0102570	0.0662010	RGCC;CDK1;CDKN3
23	cellular response to nitrogen compound (GO:1901699)	0.0117907	0.0662010	CDK1;LAMTOR2;ATP6V0E2
23	positive regulation of protein kinase activity (GO:0045860)	0.0131397	0.0702421	RGCC;CDK1;LAMTOR2
23	chromatin modification (GO:0016568)	0.0146566	0.0722722	HMGA1;CDK1;HMGA2
23	positive regulation of kinase activity (GO:0033674)	0.0150718	0.0729070	RGCC;CDK1;LAMTOR2
23	Fanconi anemia pathway Homo sapiens hsa03460	0.0000261	0.0006528	EME1;UBE2T;FANCA
23	Formation of Senescence-Associated Heterochromatin Foci (SAHF) Homo sapiens R-HSA-2559584	0.0000008	0.0001446	HMGA1;HMGA2;LMNB1
23	Fanconi Anemia Pathway Homo sapiens R-HSA-6783310	0.0000074	0.0006872	EME1;UBE2T;FANCA
23	DNA Damage/Telomere Stress Induced Senescence Homo sapiens R-HSA-2559586	0.0000361	0.0019169	HMGA1;HMGA2;LMNB1
23	Cellular responses to stress Homo sapiens R-HSA-2262752	0.0000412	0.0019169	HMGA1;CHMP4C;HMGA2;LAMTOR2;LMNB1
23	Resolution of Sister Chromatid Cohesion Homo sapiens R-HSA-2500257	0.0001692	0.0049499	CDCA5;CDK1;CDCA8
23	M Phase Homo sapiens R-HSA-68886	0.0001907	0.0049499	CDCA5;CDK1;CDCA8;LMNB1
23	Mitotic Prometaphase Homo sapiens R-HSA-68877	0.0002129	0.0049499	CDCA5;CDK1;CDCA8
23	Cellular Senescence Homo sapiens R-HSA-2559583	0.0007046	0.0145618	HMGA1;HMGA2;LMNB1
23	Mitotic Anaphase Homo sapiens R-HSA-68882	0.0008679	0.0149220	CDCA5;CDCA8;LMNB1
23	Mitotic Metaphase and Anaphase Homo sapiens R-HSA-2555396	0.0008825	0.0149220	CDCA5;CDCA8;LMNB1
23	Cell Cycle, Mitotic Homo sapiens R-HSA-69278	0.0014774	0.0196281	CDCA5;CDK1;CDCA8;LMNB1
23	Cell Cycle Homo sapiens R-HSA-1640170	0.0030941	0.0359691	CDCA5;CDK1;CDCA8;LMNB1
23	DNA Repair Homo sapiens R-HSA-73894	0.0036078	0.0394735	EME1;UBE2T;FANCA
23	Transcriptional Regulation by TP53 Homo sapiens R-HSA-3700989	0.0062927	0.0532015	RGCC;CDK1;LAMTOR2
23	Generic Transcription Pathway Homo sapiens R-HSA-212436	0.0578435	0.1397259	RGCC;CDK1;LAMTOR2
23	Signal Transduction Homo sapiens R-HSA-162582	0.1254747	0.2201726	SMAD1;CDK1;CDCA8;LAMTOR2;ATP6V0E2
23	Gene Expression Homo sapiens R-HSA-74160	0.2651792	0.3399245	RGCC;CDK1;LAMTOR2
24	regulation of chromosome segregation (GO:0051983)	0.0000000	0.0000000	ESPL1;UBE2C;TTK;NEK2;BUB1;AURKB;MAD2L1
24	mitotic cell cycle (GO:0000278)	0.0000000	0.0000000	ESPL1;PTTG1;UBE2C;NEK2;TYMS;BUB1;AURKB;MAD2L1;SPC25
24	chromosome segregation (GO:0007059)	0.0000000	0.0000000	ESPL1;PTTG1;NEK2;BUB1;MAD2L1;SPC25
24	negative regulation of chromosome segregation (GO:0051985)	0.0000000	0.0000000	ESPL1;UBE2C;TTK;BUB1;MAD2L1
24	spindle checkpoint (GO:0031577)	0.0000000	0.0000000	UBE2C;TTK;BUB1;AURKB;MAD2L1
24	regulation of mitotic sister chromatid separation (GO:0010965)	0.0000000	0.0000000	ESPL1;UBE2C;TTK;BUB1;MAD2L1
24	regulation of sister chromatid segregation (GO:0033045)	0.0000000	0.0000000	ESPL1;UBE2C;TTK;BUB1;MAD2L1
24	regulation of mitotic sister chromatid segregation (GO:0033047)	0.0000000	0.0000000	ESPL1;UBE2C;TTK;BUB1;MAD2L1
24	regulation of mitotic metaphase/anaphase transition (GO:0030071)	0.0000000	0.0000000	ESPL1;UBE2C;TTK;BUB1;MAD2L1
24	regulation of metaphase/anaphase transition of cell cycle (GO:1902099)	0.0000000	0.0000000	ESPL1;UBE2C;TTK;BUB1;MAD2L1
24	regulation of mitosis (GO:0007088)	0.0000000	0.0000000	ESPL1;UBE2C;TTK;NEK2;BUB1;MAD2L1
24	regulation of mitotic cell cycle (GO:0007346)	0.0000000	0.0000000	ESPL1;UBE2C;EIF4EBP1;TTK;NEK2;BUB1;AURKB;MAD2L1
24	regulation of cell division (GO:0051302)	0.0000000	0.0000000	ESPL1;UBE2C;TTK;NEK2;BUB1;AURKB;MAD2L1
24	negative regulation of organelle organization (GO:0010639)	0.0000000	0.0000000	ESPL1;UBE2C;TTK;NEK2;BUB1;AURKB;MAD2L1
24	regulation of nuclear division (GO:0051783)	0.0000000	0.0000001	ESPL1;UBE2C;TTK;NEK2;BUB1;MAD2L1
24	negative regulation of cell division (GO:0051782)	0.0000000	0.0000001	UBE2C;TTK;BUB1;AURKB;MAD2L1
24	negative regulation of cellular component organization (GO:0051129)	0.0000000	0.0000001	ESPL1;UBE2C;EIF4EBP1;TTK;NEK2;BUB1;AURKB;MAD2L1
24	negative regulation of chromosome organization (GO:2001251)	0.0000000	0.0000002	ESPL1;UBE2C;TTK;BUB1;MAD2L1
24	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031145)	0.0000000	0.0000002	PTTG1;UBE2C;UBE2S;AURKB;MAD2L1
24	mitotic spindle assembly checkpoint (GO:0007094)	0.0000000	0.0000004	UBE2C;TTK;BUB1;MAD2L1
24	spindle assembly checkpoint (GO:0071173)	0.0000000	0.0000004	UBE2C;TTK;BUB1;MAD2L1
24	negative regulation of mitotic metaphase/anaphase transition (GO:0045841)	0.0000000	0.0000004	UBE2C;TTK;BUB1;MAD2L1
24	negative regulation of sister chromatid segregation (GO:0033046)	0.0000000	0.0000004	UBE2C;TTK;BUB1;MAD2L1
24	negative regulation of mitotic sister chromatid separation (GO:2000816)	0.0000000	0.0000004	UBE2C;TTK;BUB1;MAD2L1
24	negative regulation of mitotic sister chromatid segregation (GO:0033048)	0.0000000	0.0000004	UBE2C;TTK;BUB1;MAD2L1
24	negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)	0.0000000	0.0000004	UBE2C;TTK;BUB1;MAD2L1
24	mitotic spindle checkpoint (GO:0071174)	0.0000000	0.0000005	UBE2C;TTK;BUB1;MAD2L1
24	mitotic cell cycle checkpoint (GO:0007093)	0.0000000	0.0000005	UBE2C;TTK;BUB1;AURKB;MAD2L1
24	regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032434)	0.0000000	0.0000008	ESPL1;UBE2C;TTK;BUB1;MAD2L1
24	regulation of mitotic cell cycle phase transition (GO:1901990)	0.0000001	0.0000009	ESPL1;UBE2C;TTK;BUB1;AURKB;MAD2L1
24	negative regulation of mitosis (GO:0045839)	0.0000001	0.0000009	UBE2C;TTK;BUB1;MAD2L1
24	negative regulation of cell cycle process (GO:0010948)	0.0000001	0.0000010	ESPL1;UBE2C;TTK;BUB1;AURKB;MAD2L1
24	regulation of cell cycle phase transition (GO:1901987)	0.0000001	0.0000012	ESPL1;UBE2C;TTK;BUB1;AURKB;MAD2L1
24	regulation of proteasomal protein catabolic process (GO:0061136)	0.0000001	0.0000015	ESPL1;UBE2C;TTK;BUB1;MAD2L1
24	regulation of cell cycle process (GO:0010564)	0.0000001	0.0000015	ESPL1;UBE2C;TTK;NEK2;BUB1;AURKB;MAD2L1
24	negative regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032435)	0.0000001	0.0000016	UBE2C;TTK;BUB1;MAD2L1
24	negative regulation of nuclear division (GO:0051784)	0.0000001	0.0000018	UBE2C;TTK;BUB1;MAD2L1
24	negative regulation of proteasomal protein catabolic process (GO:1901799)	0.0000002	0.0000019	UBE2C;TTK;BUB1;MAD2L1
24	regulation of proteolysis involved in cellular protein catabolic process (GO:1903050)	0.0000002	0.0000020	ESPL1;UBE2C;TTK;BUB1;MAD2L1
24	regulation of cellular protein catabolic process (GO:1903362)	0.0000002	0.0000025	ESPL1;UBE2C;TTK;BUB1;MAD2L1
24	cell cycle checkpoint (GO:0000075)	0.0000002	0.0000025	UBE2C;TTK;BUB1;AURKB;MAD2L1
24	negative regulation of proteolysis involved in cellular protein catabolic process (GO:1903051)	0.0000002	0.0000027	UBE2C;TTK;BUB1;MAD2L1
24	negative regulation of cellular protein catabolic process (GO:1903363)	0.0000003	0.0000031	UBE2C;TTK;BUB1;MAD2L1
24	regulation of chromosome organization (GO:0033044)	0.0000003	0.0000038	ESPL1;UBE2C;TTK;BUB1;MAD2L1
24	spindle organization (GO:0007051)	0.0000005	0.0000054	ESPL1;TTK;NEK2;SPC25
24	negative regulation of mitotic cell cycle phase transition (GO:1901991)	0.0000006	0.0000063	UBE2C;TTK;BUB1;AURKB;MAD2L1
24	mitotic sister chromatid segregation (GO:0000070)	0.0000007	0.0000071	ESPL1;NEK2;MAD2L1
24	negative regulation of cell cycle phase transition (GO:1901988)	0.0000007	0.0000073	UBE2C;TTK;BUB1;AURKB;MAD2L1
24	proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161)	0.0000008	0.0000081	PTTG1;UBE2C;UBE2S;AURKB;MAD2L1
24	proteasomal protein catabolic process (GO:0010498)	0.0000010	0.0000094	PTTG1;UBE2C;UBE2S;AURKB;MAD2L1
24	sister chromatid segregation (GO:0000819)	0.0000011	0.0000101	ESPL1;NEK2;MAD2L1
24	negative regulation of mitotic cell cycle (GO:0045930)	0.0000011	0.0000106	UBE2C;TTK;BUB1;AURKB;MAD2L1
24	negative regulation of cell cycle (GO:0045786)	0.0000014	0.0000129	ESPL1;UBE2C;TTK;BUB1;AURKB;MAD2L1
24	negative regulation of protein catabolic process (GO:0042177)	0.0000015	0.0000134	UBE2C;TTK;BUB1;MAD2L1
24	mitotic nuclear division (GO:0007067)	0.0000018	0.0000157	PTTG1;NEK2;BUB1;AURKB;SPC25
24	positive regulation of mitotic cell cycle (GO:0045931)	0.0000019	0.0000165	ESPL1;UBE2C;EIF4EBP1;MAD2L1
24	microtubule cytoskeleton organization (GO:0000226)	0.0000020	0.0000168	ESPL1;TTK;NEK2;AURKB;SPC25
24	regulation of protein catabolic process (GO:0042176)	0.0000027	0.0000220	ESPL1;UBE2C;TTK;BUB1;MAD2L1
24	mitotic spindle organization (GO:0007052)	0.0000027	0.0000220	TTK;NEK2;SPC25
24	protein catabolic process (GO:0030163)	0.0000031	0.0000252	PTTG1;UBE2C;UBE2S;AURKB;MAD2L1
24	positive regulation of cell cycle (GO:0045787)	0.0000037	0.0000291	ESPL1;UBE2C;EIF4EBP1;AURKB;MAD2L1
24	nuclear division (GO:0000280)	0.0000052	0.0000402	PTTG1;NEK2;BUB1;AURKB;SPC25
24	negative regulation of proteolysis (GO:0045861)	0.0000055	0.0000422	PTTG1;UBE2C;TTK;BUB1;MAD2L1
24	negative regulation of protein processing (GO:0010955)	0.0000069	0.0000510	PTTG1;UBE2C;TTK;BUB1;MAD2L1
24	negative regulation of protein maturation (GO:1903318)	0.0000069	0.0000510	PTTG1;UBE2C;TTK;BUB1;MAD2L1
24	negative regulation of cellular catabolic process (GO:0031330)	0.0000075	0.0000545	UBE2C;TTK;BUB1;MAD2L1
24	organelle fission (GO:0048285)	0.0000079	0.0000567	PTTG1;NEK2;BUB1;AURKB;SPC25
24	ubiquitin-dependent protein catabolic process (GO:0006511)	0.0000121	0.0000857	PTTG1;UBE2C;UBE2S;AURKB;MAD2L1
24	modification-dependent protein catabolic process (GO:0019941)	0.0000137	0.0000953	PTTG1;UBE2C;UBE2S;AURKB;MAD2L1
24	modification-dependent macromolecule catabolic process (GO:0043632)	0.0000144	0.0000990	PTTG1;UBE2C;UBE2S;AURKB;MAD2L1
24	proteolysis involved in cellular protein catabolic process (GO:0051603)	0.0000193	0.0001307	PTTG1;UBE2C;UBE2S;AURKB;MAD2L1
24	negative regulation of catabolic process (GO:0009895)	0.0000218	0.0001450	UBE2C;TTK;BUB1;MAD2L1
24	chromosome organization (GO:0051276)	0.0000287	0.0001890	ESPL1;PTTG1;NEK2;MAD2L1
24	microtubule-based process (GO:0007017)	0.0000330	0.0002138	ESPL1;TTK;NEK2;AURKB;SPC25
24	positive regulation of cell cycle process (GO:0090068)	0.0000386	0.0002439	ESPL1;UBE2C;AURKB;MAD2L1
24	regulation of ubiquitin-protein transferase activity (GO:0051438)	0.0001023	0.0006297	UBE2C;UBE2S;MAD2L1
24	regulation of ligase activity (GO:0051340)	0.0001178	0.0007157	UBE2C;UBE2S;MAD2L1
24	response to organophosphorus (GO:0046683)	0.0001531	0.0009188	KCNJ11;KCNQ1;TYMS
24	positive regulation of cell division (GO:0051781)	0.0001609	0.0009537	ESPL1;UBE2C;AURKB
24	cellular potassium ion transport (GO:0071804)	0.0001993	0.0011387	KCNJ11;KCNQ1;KCNN4
24	potassium ion transmembrane transport (GO:0071805)	0.0001993	0.0011387	KCNJ11;KCNQ1;KCNN4
24	potassium ion transport (GO:0006813)	0.0003168	0.0017680	KCNJ11;KCNQ1;KCNN4
24	inorganic cation transmembrane transport (GO:0098662)	0.0005535	0.0029519	KCNJ11;TRPV6;KCNQ1;KCNN4
24	regulation of protein ubiquitination (GO:0031396)	0.0008519	0.0044448	UBE2C;UBE2S;MAD2L1
24	regulation of protein modification by small protein conjugation or removal (GO:1903320)	0.0010513	0.0054260	UBE2C;UBE2S;MAD2L1
24	cellular protein complex assembly (GO:0043623)	0.0014670	0.0073349	UBE2C;UBE2S;AURKB
24	regulation of membrane potential (GO:0042391)	0.0016372	0.0079379	KCNJ11;KCNQ1;KCNN4
24	response to alcohol (GO:0097305)	0.0017819	0.0085533	KCNJ11;EIF4EBP1;TYMS
24	mitotic cell cycle phase transition (GO:0044772)	0.0018382	0.0087361	EIF4EBP1;NEK2;TYMS
24	cell cycle phase transition (GO:0044770)	0.0018956	0.0088339	EIF4EBP1;NEK2;TYMS
24	response to drug (GO:0042493)	0.0036828	0.0156436	KCNJ11;KCNQ1;TYMS
24	monovalent inorganic cation transport (GO:0015672)	0.0046250	0.0188136	KCNJ11;KCNQ1;KCNN4
24	cellular response to organonitrogen compound (GO:0071417)	0.0055882	0.0221679	KCNJ11;KCNQ1;EIF4EBP1
24	synaptic transmission (GO:0007268)	0.0064977	0.0251524	KCNJ11;KCNQ1;KCNN4
24	cellular response to nitrogen compound (GO:1901699)	0.0066644	0.0255914	KCNJ11;KCNQ1;EIF4EBP1
24	Cell cycle Homo sapiens hsa04110	0.0000001	0.0000019	ESPL1;PTTG1;TTK;BUB1;MAD2L1
24	Oocyte meiosis Homo sapiens hsa04114	0.0000039	0.0000546	ESPL1;PTTG1;BUB1;MAD2L1
24	Separation of Sister Chromatids Homo sapiens R-HSA-2467813	0.0000000	0.0000000	ESPL1;PTTG1;UBE2C;BUB1;AURKB;MAD2L1;SPC25
24	Cell Cycle, Mitotic Homo sapiens R-HSA-69278	0.0000000	0.0000000	ESPL1;PTTG1;UBE2C;NEK2;TYMS;BUB1;AURKB;MAD2L1;SPC25
24	Mitotic Anaphase Homo sapiens R-HSA-68882	0.0000000	0.0000000	ESPL1;PTTG1;UBE2C;BUB1;AURKB;MAD2L1;SPC25
24	Mitotic Metaphase and Anaphase Homo sapiens R-HSA-2555396	0.0000000	0.0000000	ESPL1;PTTG1;UBE2C;BUB1;AURKB;MAD2L1;SPC25
24	Cell Cycle Homo sapiens R-HSA-1640170	0.0000000	0.0000000	ESPL1;PTTG1;UBE2C;NEK2;TYMS;BUB1;AURKB;MAD2L1;SPC25
24	M Phase Homo sapiens R-HSA-68886	0.0000000	0.0000000	ESPL1;PTTG1;UBE2C;BUB1;AURKB;MAD2L1;SPC25
24	APC/C-mediated degradation of cell cycle proteins Homo sapiens R-HSA-174143	0.0000000	0.0000001	PTTG1;UBE2C;NEK2;AURKB;MAD2L1
24	Regulation of mitotic cell cycle Homo sapiens R-HSA-453276	0.0000000	0.0000001	PTTG1;UBE2C;NEK2;AURKB;MAD2L1
24	APC/C:Cdc20 mediated degradation of mitotic proteins Homo sapiens R-HSA-176409	0.0000005	0.0000058	PTTG1;UBE2C;NEK2;MAD2L1
24	Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins Homo sapiens R-HSA-176814	0.0000005	0.0000058	PTTG1;UBE2C;NEK2;MAD2L1
24	APC-Cdc20 mediated degradation of Nek2A Homo sapiens R-HSA-179409	0.0000014	0.0000137	UBE2C;NEK2;MAD2L1
24	Resolution of Sister Chromatid Cohesion Homo sapiens R-HSA-2500257	0.0000016	0.0000147	BUB1;AURKB;MAD2L1;SPC25
24	Mitotic Prometaphase Homo sapiens R-HSA-68877	0.0000022	0.0000186	BUB1;AURKB;MAD2L1;SPC25
24	RHO GTPases Activate Formins Homo sapiens R-HSA-5663220	0.0000029	0.0000222	BUB1;AURKB;MAD2L1;SPC25
24	APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Homo sapiens R-HSA-174178	0.0000337	0.0002370	PTTG1;UBE2C;AURKB
24	APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint Homo sapiens R-HSA-179419	0.0000351	0.0002370	UBE2C;NEK2;MAD2L1
24	RHO GTPase Effectors Homo sapiens R-HSA-195258	0.0000686	0.0004359	BUB1;AURKB;MAD2L1;SPC25
24	Potassium Channels Homo sapiens R-HSA-1296071	0.0000910	0.0005457	KCNJ11;KCNQ1;KCNN4
24	Signaling by Rho GTPases Homo sapiens R-HSA-194315	0.0002784	0.0013666	BUB1;AURKB;MAD2L1;SPC25
24	Neuronal System Homo sapiens R-HSA-112316	0.0023290	0.0096743	KCNJ11;KCNQ1;KCNN4
24	Transmembrane transport of small molecules Homo sapiens R-HSA-382551	0.0152531	0.0457593	KCNJ11;TRPV6;FTH1
24	Signal Transduction Homo sapiens R-HSA-162582	0.0613867	0.1052343	EIF4EBP1;BUB1;AURKB;MAD2L1;SPC25
25	superoxide anion generation (GO:0042554)	0.0000000	0.0000030	NCF1;CYBB;NOX4;CYBA
25	positive regulation of cellular component biogenesis (GO:0044089)	0.0000001	0.0000345	BAIAP2L1;MYO3B;RAC2;EPS8L1;NOX4;ESPN;MPP7
25	superoxide metabolic process (GO:0006801)	0.0000002	0.0000355	NCF1;CYBB;NOX4;CYBA
25	hydrogen peroxide biosynthetic process (GO:0050665)	0.0000003	0.0000426	NCF1;CYBB;CYBA
25	reactive oxygen species biosynthetic process (GO:1903409)	0.0000005	0.0000486	NCF1;CYBB;CYBA
25	positive regulation of cell projection organization (GO:0031346)	0.0000007	0.0000588	PRKCI;MYO3B;RAC2;EPS8L1;ESPN;SHANK1
25	respiratory burst (GO:0045730)	0.0000023	0.0001610	NCF1;CYBB;CYBA
25	reactive oxygen species metabolic process (GO:0072593)	0.0000108	0.0006734	NCF1;CYBB;NOX4;CYBA
25	establishment or maintenance of cell polarity (GO:0007163)	0.0000215	0.0010772	PARD6B;PRKCI;WWC1;MPP7
25	hydrogen peroxide metabolic process (GO:0042743)	0.0000216	0.0010772	NCF1;CYBB;CYBA
25	tight junction assembly (GO:0070830)	0.0000359	0.0014609	PARD6B;PRKCI;MPP7
25	phagosome maturation (GO:0090382)	0.0000359	0.0014609	NCF1;CYBB;CYBA
25	regulation of cell projection organization (GO:0031344)	0.0000381	0.0014609	PRKCI;MYO3B;RAC2;EPS8L1;ESPN;SHANK1
25	regulation of cell projection assembly (GO:0060491)	0.0000441	0.0015712	MYO3B;RAC2;EPS8L1;ESPN
25	neuromuscular process controlling balance (GO:0050885)	0.0000554	0.0018244	CLIC5;RAC3;SHANK1
25	regulation of small GTPase mediated signal transduction (GO:0051056)	0.0000585	0.0018244	DEPDC1B;RAC2;EPS8L1;RAC3;RHOV
25	establishment of cell polarity (GO:0030010)	0.0000716	0.0021016	PRKCI;WWC1;MPP7
25	regulation of cytoskeleton organization (GO:0051493)	0.0002530	0.0057806	BAIAP2L1;NOX4;ESPN;S100A9;SHANK1
25	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:0002479)	0.0002549	0.0057806	NCF1;CYBB;CYBA
25	cell-cell junction assembly (GO:0007043)	0.0002755	0.0059306	PARD6B;PRKCI;MPP7
25	antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)	0.0002971	0.0059306	NCF1;CYBB;CYBA
25	neuromuscular process (GO:0050905)	0.0002971	0.0059306	CLIC5;RAC3;SHANK1
25	inflammatory response (GO:0006954)	0.0003518	0.0067526	NCF1;CYBB;NOX4;CYBA;S100A9
25	interaction with host (GO:0051701)	0.0004650	0.0085941	NCF1;CYBB;CYBA
25	antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)	0.0006653	0.0114477	NCF1;CYBB;CYBA
25	small GTPase mediated signal transduction (GO:0007264)	0.0007118	0.0114655	DEPDC1B;RAC2;EPS8L1;RAC3;RHOV
25	tissue homeostasis (GO:0001894)	0.0012416	0.0193610	HOMER2;RAC2;NOX4
25	adult behavior (GO:0030534)	0.0016029	0.0228524	HOMER2;SHANK2;SHANK1
25	regulation of ion transmembrane transport (GO:0034765)	0.0017031	0.0235249	CLIC5;CYBB;PTPN3;SHANK1
25	actin filament organization (GO:0007015)	0.0019129	0.0235249	PRKCI;RAC2;ESPN
25	regulation of transmembrane transport (GO:0034762)	0.0019748	0.0235249	CLIC5;CYBB;PTPN3;SHANK1
25	cell junction assembly (GO:0034329)	0.0022987	0.0259434	PARD6B;PRKCI;MPP7
25	cell-cell junction organization (GO:0045216)	0.0023397	0.0259434	PARD6B;PRKCI;MPP7
25	antigen processing and presentation of exogenous peptide antigen (GO:0002478)	0.0027751	0.0282612	NCF1;CYBB;CYBA
25	antigen processing and presentation of exogenous antigen (GO:0019884)	0.0028678	0.0286209	NCF1;CYBB;CYBA
25	antigen processing and presentation of peptide antigen (GO:0048002)	0.0034641	0.0326152	NCF1;CYBB;CYBA
25	cell junction organization (GO:0034330)	0.0036785	0.0339923	PARD6B;PRKCI;MPP7
25	anatomical structure homeostasis (GO:0060249)	0.0048072	0.0420842	HOMER2;RAC2;NOX4
25	cell projection assembly (GO:0030031)	0.0051353	0.0441813	BAIAP2L1;RAC2;RAC3
25	antigen processing and presentation (GO:0019882)	0.0059770	0.0505514	NCF1;CYBB;CYBA
25	regulation of actin cytoskeleton organization (GO:0032956)	0.0071395	0.0575494	BAIAP2L1;NOX4;SHANK1
25	actin cytoskeleton organization (GO:0030036)	0.0082486	0.0643132	DIAPH3;RAC2;RAC3
25	behavior (GO:0007610)	0.0085333	0.0650906	HOMER2;ESPN;SHANK2;SHANK1
25	regulation of actin filament-based process (GO:0032970)	0.0086092	0.0650906	BAIAP2L1;NOX4;SHANK1
25	actin filament-based process (GO:0030029)	0.0134283	0.0906210	DIAPH3;RAC2;RAC3
25	positive regulation of cell development (GO:0010720)	0.0208674	0.0946726	PRKCI;RAC3;SHANK1
25	single-organism behavior (GO:0044708)	0.0214812	0.0946726	HOMER2;SHANK2;SHANK1
25	cellular response to organonitrogen compound (GO:0071417)	0.0298064	0.1040099	PRKCI;NOX4;CYBA
25	cellular component morphogenesis (GO:0032989)	0.0348281	0.1148594	PARD6B;NOX4;SHANK1
25	cellular response to nitrogen compound (GO:1901699)	0.0350295	0.1148594	PRKCI;NOX4;CYBA
25	sensory perception (GO:0007600)	0.0389735	0.1164537	CLIC5;MYO3B;ESPN
25	response to other organism (GO:0051707)	0.0400479	0.1180881	BAIAP2L1;NCF1;S100A9
25	Leukocyte transendothelial migration Homo sapiens hsa04670	0.0000413	0.0016510	NCF1;RAC2;CYBB;CYBA
25	Rap1 signaling pathway Homo sapiens hsa04015	0.0003876	0.0054512	PARD6B;PRKCI;RAC2;RAC3
25	Regulation of actin cytoskeleton Homo sapiens hsa04810	0.0004088	0.0054512	DIAPH3;RAC2;PAK6;RAC3
25	Glutamatergic synapse Homo sapiens hsa04724	0.0008687	0.0086871	HOMER2;SHANK2;SHANK1
25	Axon guidance Homo sapiens hsa04360	0.0011869	0.0088433	RAC2;PAK6;RAC3
25	Osteoclast differentiation Homo sapiens hsa04380	0.0013265	0.0088433	NCF1;CYBB;CYBA
25	Wnt signaling pathway Homo sapiens hsa04310	0.0016356	0.0091641	VANGL1;RAC2;RAC3
25	Hippo signaling pathway Homo sapiens hsa04390	0.0020240	0.0091641	PARD6B;PRKCI;WWC1
25	Phagosome Homo sapiens hsa04145	0.0020619	0.0091641	NCF1;CYBB;CYBA
25	Focal adhesion Homo sapiens hsa04510	0.0044308	0.0139388	RAC2;PAK6;RAC3
25	Ras signaling pathway Homo sapiens hsa04014	0.0061249	0.0139388	RAC2;PAK6;RAC3
25	RHO GTPases Activate NADPH Oxidases Homo sapiens R-HSA-5668599	0.0000000	0.0000002	NCF1;RAC2;CYBB;CYBA
25	Signaling by Rho GTPases Homo sapiens R-HSA-194315	0.0000001	0.0000024	DEPDC1B;DIAPH3;NCF1;RAC2;RAC3;CYBB;CYBA;RHOV
25	Cross-presentation of particulate exogenous antigens (phagosomes) Homo sapiens R-HSA-1236973	0.0000002	0.0000033	NCF1;CYBB;CYBA
25	Detoxification of Reactive Oxygen Species Homo sapiens R-HSA-3299685	0.0000216	0.0002034	CYBB;NOX4;CYBA
25	ROS, RNS production in response to bacteria Homo sapiens R-HSA-1222556	0.0000236	0.0002034	NCF1;CYBB;CYBA
25	Rho GTPase cycle Homo sapiens R-HSA-194840	0.0000470	0.0003370	DEPDC1B;RAC2;RAC3;RHOV
25	RHO GTPase Effectors Homo sapiens R-HSA-195258	0.0000574	0.0003527	DIAPH3;NCF1;RAC2;CYBB;CYBA
25	Antigen processing-Cross presentation Homo sapiens R-HSA-1236975	0.0003316	0.0017825	NCF1;CYBB;CYBA
25	Signal Transduction Homo sapiens R-HSA-162582	0.0050185	0.0196177	PRKCI;DEPDC1B;DIAPH3;NCF1;WWC1;RAC2;RAC3;CYBB;CYBA;RHOV
25	Class I MHC mediated antigen processing & presentation Homo sapiens R-HSA-983169	0.0136664	0.0419753	NCF1;CYBB;CYBA
25	VEGFA-VEGFR2 Pathway Homo sapiens R-HSA-4420097	0.0155297	0.0445184	NCF1;CYBB;CYBA
25	Signaling by VEGF Homo sapiens R-HSA-194138	0.0165796	0.0445576	NCF1;CYBB;CYBA
25	Cellular responses to stress Homo sapiens R-HSA-2262752	0.0222624	0.0481059	CYBB;NOX4;CYBA
25	Adaptive Immune System Homo sapiens R-HSA-1280218	0.1297126	0.1743013	NCF1;CYBB;CYBA
25	Immune System Homo sapiens R-HSA-168256	0.2495130	0.3065446	IL32;NCF1;CYBB;CYBA
26	positive regulation of release of cytochrome c from mitochondria (GO:0090200)	0.0000002	0.0000536	BIK;PMAIP1;BAK1
26	regulation of release of cytochrome c from mitochondria (GO:0090199)	0.0000007	0.0001095	BIK;PMAIP1;BAK1
26	apoptotic mitochondrial changes (GO:0008637)	0.0000022	0.0002130	BIK;PMAIP1;BAK1
26	positive regulation of mitochondrion organization (GO:0010822)	0.0000026	0.0002130	BIK;PMAIP1;BAK1
26	intrinsic apoptotic signaling pathway in response to DNA damage (GO:0008630)	0.0000049	0.0003223	BCL2A1;PMAIP1;BAK1
26	regulation of mitochondrion organization (GO:0010821)	0.0000091	0.0004987	BIK;PMAIP1;BAK1
26	regulation of apoptotic signaling pathway (GO:2001233)	0.0000116	0.0005447	BCL2A1;BIK;PMAIP1;BAK1
26	positive regulation of apoptotic signaling pathway (GO:2001235)	0.0000471	0.0014404	BIK;PMAIP1;BAK1
26	intrinsic apoptotic signaling pathway (GO:0097193)	0.0000488	0.0014404	BCL2A1;PMAIP1;BAK1
26	mitochondrion organization (GO:0007005)	0.0000569	0.0014404	BIK;PMAIP1;BAK1
26	negative regulation of neurogenesis (GO:0050768)	0.0000701	0.0014933	RTN4R;LINGO1;MYCN
26	negative regulation of nervous system development (GO:0051961)	0.0000928	0.0015264	RTN4R;LINGO1;MYCN
26	protein maturation (GO:0051604)	0.0001079	0.0015423	PMAIP1;BAK1;TSPAN33
26	negative regulation of cell development (GO:0010721)	0.0001342	0.0017664	RTN4R;LINGO1;MYCN
26	apoptotic signaling pathway (GO:0097190)	0.0003381	0.0034765	BCL2A1;PMAIP1;BAK1
26	positive regulation of organelle organization (GO:0010638)	0.0003791	0.0037796	BIK;PMAIP1;BAK1
26	Apoptosis Homo sapiens hsa04210	0.0000273	0.0002734	BCL2A1;PMAIP1;BAK1
27	response to other organism (GO:0051707)	0.0000006	0.0002708	SPN;CD4;FCER1G;CARD9;CLEC5A;ITGB6;TREM1
27	regulation of cytokine production (GO:0001817)	0.0000008	0.0002708	LYN;SPN;CD4;FCER1G;CARD9;CLEC5A;CD24
27	T cell costimulation (GO:0031295)	0.0000016	0.0002848	LYN;SPN;CD4;CD24
27	lymphocyte costimulation (GO:0031294)	0.0000017	0.0002848	LYN;SPN;CD4;CD24
27	embryonic skeletal system morphogenesis (GO:0048704)	0.0000021	0.0002848	HOXB4;HOXB7;HOXB6;HOXB5
27	homeostasis of number of cells (GO:0048872)	0.0000041	0.0004684	LYN;CD7;MAP7;HOXB6
27	skeletal system morphogenesis (GO:0048705)	0.0000061	0.0005959	HOXB4;HOXB7;HOXB6;HOXB5
27	positive regulation of leukocyte activation (GO:0002696)	0.0000103	0.0007836	LYN;SPN;CD4;FCER1G;CD24
27	embryonic organ morphogenesis (GO:0048562)	0.0000103	0.0007836	HOXB4;HOXB7;HOXB6;HOXB5
27	positive regulation of cell activation (GO:0050867)	0.0000123	0.0008433	LYN;SPN;CD4;FCER1G;CD24
27	positive regulation of tumor necrosis factor production (GO:0032760)	0.0000171	0.0010593	SPN;FCER1G;CARD9
27	positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557)	0.0000195	0.0011113	SPN;FCER1G;CARD9
27	anterior/posterior pattern specification (GO:0009952)	0.0000241	0.0012655	HOXB4;HOXB7;HOXB6;HOXB5
27	positive regulation of cytokine production (GO:0001819)	0.0000299	0.0013829	SPN;CD4;FCER1G;CARD9;CLEC5A
27	defense response to other organism (GO:0098542)	0.0000304	0.0013829	SPN;CD4;FCER1G;CARD9;TREM1
27	defense response to bacterium (GO:0042742)	0.0000481	0.0019323	SPN;CD4;FCER1G;CARD9
27	positive regulation of T cell activation (GO:0050870)	0.0000594	0.0022550	LYN;SPN;CD4;CD24
27	regulation of leukocyte activation (GO:0002694)	0.0000692	0.0023636	LYN;SPN;CD4;FCER1G;CD24
27	response to bacterium (GO:0009617)	0.0000755	0.0024547	SPN;CD4;FCER1G;CARD9
27	regulation of tumor necrosis factor production (GO:0032680)	0.0000955	0.0027942	SPN;FCER1G;CARD9
27	regulation of cell activation (GO:0050865)	0.0000982	0.0027942	LYN;SPN;CD4;FCER1G;CD24
27	regulation of tumor necrosis factor superfamily cytokine production (GO:1903555)	0.0001030	0.0028144	SPN;FCER1G;CARD9
27	leukocyte migration (GO:0050900)	0.0001187	0.0030131	LYN;SPN;FCER1G;TREM1
27	integrin-mediated signaling pathway (GO:0007229)	0.0001191	0.0030131	FCER1G;ITGB8;ITGB6
27	positive regulation of lymphocyte activation (GO:0051251)	0.0001570	0.0036684	LYN;SPN;CD4;CD24
27	regulation of cytokine biosynthetic process (GO:0042035)	0.0001611	0.0036684	SPN;CD4;CARD9
27	regionalization (GO:0003002)	0.0001671	0.0036820	HOXB4;HOXB7;HOXB6;HOXB5
27	regulation of T cell activation (GO:0050863)	0.0002004	0.0040910	LYN;SPN;CD4;CD24
27	regulation of immune effector process (GO:0002697)	0.0002156	0.0040910	LYN;SPN;CD4;FCER1G
27	positive regulation of leukocyte proliferation (GO:0070665)	0.0003334	0.0058351	LYN;SPN;CD24
27	regulation of leukocyte mediated immunity (GO:0002703)	0.0003417	0.0058351	LYN;SPN;FCER1G
27	positive regulation of peptidyl-tyrosine phosphorylation (GO:0050731)	0.0005254	0.0075215	LYN;CD4;CD24
27	regulation of lymphocyte activation (GO:0051249)	0.0005880	0.0080318	LYN;SPN;CD4;CD24
27	leukocyte activation (GO:0045321)	0.0007961	0.0106611	CD4;FCER1G;BANK1;CD7
27	pattern specification process (GO:0007389)	0.0008958	0.0115438	HOXB4;HOXB7;HOXB6;HOXB5
27	regulation of lymphocyte proliferation (GO:0050670)	0.0009429	0.0119089	LYN;SPN;CD24
27	regulation of mononuclear cell proliferation (GO:0032944)	0.0009590	0.0119089	LYN;SPN;CD24
27	regulation of leukocyte proliferation (GO:0070663)	0.0010422	0.0127113	LYN;SPN;CD24
27	embryonic morphogenesis (GO:0048598)	0.0010615	0.0127194	HOXB4;HOXB7;HOXB6;HOXB5
27	organ morphogenesis (GO:0009887)	0.0010812	0.0127316	HOXB4;HOXB7;HOXB6;HOXB5
27	secretion by cell (GO:0032940)	0.0011833	0.0133876	LYN;FCER1G;TRPV4;TREM1
27	regulation of peptidyl-tyrosine phosphorylation (GO:0050730)	0.0012796	0.0138730	LYN;CD4;CD24
27	immune response-activating signal transduction (GO:0002757)	0.0014682	0.0156689	LYN;CD4;FCER1G;CARD9
27	immune response-regulating cell surface receptor signaling pathway (GO:0002768)	0.0015179	0.0159498	LYN;CD4;FCER1G;CD24
27	coagulation (GO:0050817)	0.0018991	0.0175284	LYN;SPN;FCER1G;TREM1
27	blood coagulation (GO:0007596)	0.0018991	0.0175284	LYN;SPN;FCER1G;TREM1
27	hemostasis (GO:0007599)	0.0019887	0.0181108	LYN;SPN;FCER1G;TREM1
27	activation of immune response (GO:0002253)	0.0021286	0.0188273	LYN;CD4;FCER1G;CARD9
27	response to molecule of bacterial origin (GO:0002237)	0.0026213	0.0215704	LYN;CARD9;CD24
27	regulation of inflammatory response (GO:0050727)	0.0027452	0.0220586	LYN;SPN;FCER1G
27	response to virus (GO:0009615)	0.0028405	0.0223566	CARD9;CLEC5A;ITGB6
27	taxis (GO:0042330)	0.0032770	0.0243282	SPN;FCER1G;TREM1
27	chemotaxis (GO:0006935)	0.0032770	0.0243282	SPN;FCER1G;TREM1
27	regulation of neuron projection development (GO:0010975)	0.0037147	0.0251204	LYN;TRPV4;NGEF
27	protein localization to membrane (GO:0072657)	0.0037527	0.0251287	FCER1G;MAP7;CD24
27	lymphocyte activation (GO:0046649)	0.0049157	0.0313779	CD4;BANK1;CD7
27	negative regulation of immune system process (GO:0002683)	0.0052369	0.0328145	LYN;SPN;FCER1G
27	immune response-activating cell surface receptor signaling pathway (GO:0002429)	0.0058664	0.0348416	LYN;CD4;FCER1G
27	apoptotic signaling pathway (GO:0097190)	0.0060179	0.0354331	SPN;CD24;NGEF
27	regulation of response to wounding (GO:1903034)	0.0070881	0.0387296	LYN;SPN;FCER1G
27	regulation of cell projection organization (GO:0031344)	0.0098226	0.0459511	LYN;TRPV4;NGEF
27	regulation of neuron differentiation (GO:0045664)	0.0108054	0.0482357	LYN;TRPV4;NGEF
27	nitrogen compound transport (GO:0071705)	0.0155641	0.0557036	LYN;FCER1G;TRPV4
27	positive regulation of kinase activity (GO:0033674)	0.0170297	0.0573105	LYN;CD4;CD24
27	single-organism cellular localization (GO:1902580)	0.0185711	0.0589955	FCER1G;MAP7;CD24
27	Cell adhesion molecules (CAMs) Homo sapiens hsa04514	0.0000194	0.0006408	SPN;CD4;CD6;ITGB8
27	Hematopoietic cell lineage Homo sapiens hsa04640	0.0001368	0.0022567	CD4;CD7;CD24
27	Cell surface interactions at the vascular wall Homo sapiens R-HSA-202733	0.0000050	0.0011337	LYN;SPN;FCER1G;TREM1
27	C-type lectin receptors (CLRs) Homo sapiens R-HSA-5621481	0.0000110	0.0012395	LYN;FCER1G;CARD9;PSMB9
27	Innate Immune System Homo sapiens R-HSA-168249	0.0000236	0.0017697	LYN;CD4;FCER1G;CARD9;CLEC5A;TREM1;PSMB9
27	Immune System Homo sapiens R-HSA-168256	0.0013267	0.0323636	LYN;CD4;FCER1G;CARD9;CLEC5A;TREM1;PSMB9
27	Developmental Biology Homo sapiens R-HSA-1266738	0.0017261	0.0323636	LYN;HOXB4;CD24;NGEF;PSMB9
27	Axon guidance Homo sapiens R-HSA-422475	0.0026075	0.0429547	LYN;CD24;NGEF;PSMB9
27	Hemostasis Homo sapiens R-HSA-109582	0.0033483	0.0470853	LYN;SPN;FCER1G;TREM1
27	DAP12 interactions Homo sapiens R-HSA-2172127	0.0077815	0.0823621	CLEC5A;TREM1;PSMB9
27	Signaling by Interleukins Homo sapiens R-HSA-449147	0.0098910	0.0834739	LYN;CD4;PSMB9
27	Fc epsilon receptor (FCERI) signaling Homo sapiens R-HSA-2454202	0.0100978	0.0834739	LYN;FCER1G;PSMB9
27	Adaptive Immune System Homo sapiens R-HSA-1280218	0.0103879	0.0834739	LYN;CD4;TREM1;PSMB9
27	Cytokine Signaling in Immune system Homo sapiens R-HSA-1280215	0.0331137	0.1599993	LYN;CD4;PSMB9
27	Signal Transduction Homo sapiens R-HSA-162582	0.5518913	0.5618802	LYN;NGEF;PSMB9
28	regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0000079)	0.0000000	0.0000000	CCNB2;CDKN2B;CCND1;CCNE1;CDKN2A;CKS2;CDC6;PKMYT1;CCNO;CKS1B
28	regulation of cell cycle process (GO:0010564)	0.0000000	0.0000000	CDKN2B;CDKN2A;CCNF;CDC6;FOXM1;PKMYT1;TNF;CDC20;BTC;CCND1;E2F1;E2F7;E2F8;TP73
28	mitotic cell cycle (GO:0000278)	0.0000000	0.0000000	CDKN2B;CDKN2A;CDC6;FOXM1;PKMYT1;CKS1B;CDC20;CCNB2;CCND1;CCNE1;E2F1;E2F2;E2F8
28	regulation of protein serine/threonine kinase activity (GO:0071900)	0.0000000	0.0000000	CDKN2B;CDKN2A;TNFSF15;CDC6;PKMYT1;TNF;CKS1B;CCNB2;CCND1;CCNE1;CKS2;CCNO;TP73
28	mitotic cell cycle phase transition (GO:0044772)	0.0000000	0.0000003	CCNB2;CDKN2B;CCND1;CCNE1;CDKN2A;E2F1;CDC6;FOXM1;PKMYT1;CKS1B
28	cell cycle phase transition (GO:0044770)	0.0000000	0.0000003	CCNB2;CDKN2B;CCND1;CCNE1;CDKN2A;E2F1;CDC6;FOXM1;PKMYT1;CKS1B
28	regulation of mitotic cell cycle (GO:0007346)	0.0000000	0.0000004	CDC20;BTC;CDKN2B;CCND1;CDKN2A;E2F1;CDC6;PKMYT1;TNF;E2F7;TP73
28	negative regulation of cell cycle (GO:0045786)	0.0000001	0.0000110	CDC20;CDKN2B;CCND1;CDKN2A;CCNF;LILRB1;GATA3;E2F7;E2F8;TP73
28	G1/S transition of mitotic cell cycle (GO:0000082)	0.0000001	0.0000110	CCND1;CCNE1;CDKN2A;E2F1;CDC6;PKMYT1;CKS1B
28	cell cycle G1/S phase transition (GO:0044843)	0.0000001	0.0000110	CCND1;CCNE1;CDKN2A;E2F1;CDC6;PKMYT1;CKS1B
28	regulation of mitotic cell cycle phase transition (GO:1901990)	0.0000002	0.0000190	CDC20;CDKN2B;CCND1;CDKN2A;E2F1;CDC6;E2F7;TP73
28	regulation of cell cycle phase transition (GO:1901987)	0.0000002	0.0000256	CDC20;CDKN2B;CCND1;CDKN2A;E2F1;CDC6;E2F7;TP73
28	regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)	0.0000005	0.0000461	CCNE1;E2F1;CDC6;E2F7
28	regulation of G1/S transition of mitotic cell cycle (GO:2000045)	0.0000007	0.0000641	CDKN2B;CCND1;E2F1;CDC6;E2F7;TP73
28	cell division (GO:0051301)	0.0000008	0.0000641	CCNB2;CCND1;CCNE1;CDKN2A;CCNO;CKS1B
28	regulation of cell cycle G1/S phase transition (GO:1902806)	0.0000008	0.0000641	CDKN2B;CCND1;E2F1;CDC6;E2F7;TP73
28	positive regulation of cell cycle process (GO:0090068)	0.0000010	0.0000793	BTC;CCND1;CDKN2A;CDC6;TNF;E2F7;E2F8
28	regulation of cell division (GO:0051302)	0.0000016	0.0001131	CDC20;BTC;CDC6;PKMYT1;TNF;E2F7;E2F8
28	cell cycle checkpoint (GO:0000075)	0.0000022	0.0001497	CDC20;CDKN2B;CCND1;E2F1;CDC6;TP73
28	negative regulation of cell cycle process (GO:0010948)	0.0000027	0.0001754	CDC20;CDKN2B;CCND1;CCNF;E2F7;E2F8;TP73
28	regulation of cytokine biosynthetic process (GO:0042035)	0.0000032	0.0001977	PRKCQ;LILRB1;LTB;GATA3;TNF
28	regulation of DNA metabolic process (GO:0051052)	0.0000035	0.0002110	SPI1;CDKN2A;CDC6;FOXM1;KPNA2;E2F7;E2F8
28	positive regulation of cell cycle (GO:0045787)	0.0000048	0.0002765	BTC;CCND1;CDKN2A;CDC6;TNF;E2F7;E2F8
28	regulation of cytokine secretion (GO:0050707)	0.0000060	0.0003293	TNFSF15;LILRB1;GATA3;TNF;TNFRSF21
28	regulation of mitosis (GO:0007088)	0.0000079	0.0004139	CDC20;BTC;CDC6;PKMYT1;TNF
28	regulation of T cell proliferation (GO:0042129)	0.0000135	0.0006794	CDKN2A;PRKCQ;LILRB1;TNFRSF21;TNFSF13B
28	gland development (GO:0048732)	0.0000156	0.0007576	CCNB2;CDKN2B;CCND1;TK1;GATA3;FOXM1
28	signal transduction by p53 class mediator (GO:0072331)	0.0000175	0.0008214	E2F1;E2F2;FOXM1;E2F7;TP73
28	regulation of cytokine production (GO:0001817)	0.0000203	0.0009196	TNFSF15;PRKCQ;LILRB1;LTB;GATA3;TNF;IKBKE;TNFRSF21
28	regulation of nuclear division (GO:0051783)	0.0000217	0.0009502	CDC20;BTC;CDC6;PKMYT1;TNF
28	regulation of T cell activation (GO:0050863)	0.0000390	0.0016518	CDKN2A;PRKCQ;LILRB1;GATA3;TNFRSF21;TNFSF13B
28	intrinsic apoptotic signaling pathway in response to DNA damage (GO:0008630)	0.0000417	0.0017110	E2F1;TNF;IKBKE;TP73
28	regulation of protein secretion (GO:0050708)	0.0000455	0.0018090	TNFSF15;LILRB1;GATA3;TNF;TNFRSF21
28	activation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0006919)	0.0000507	0.0019333	CDKN2A;TNFSF15;TNFSF10;TNF
28	negative regulation of protein modification process (GO:0031400)	0.0000564	0.0019333	CDC20;CDKN2B;SPI1;CDKN2A;DNMT3B;PTK6;TP73
28	DNA integrity checkpoint (GO:0031570)	0.0000582	0.0019333	CCND1;E2F1;CDC6;TP73
28	cell-type specific apoptotic process (GO:0097285)	0.0000582	0.0019333	E2F1;E2F2;TNF;TNFRSF21
28	liver development (GO:0001889)	0.0000582	0.0019333	CDKN2B;CCND1;TK1;FOXM1
28	regulation of lymphocyte proliferation (GO:0050670)	0.0000589	0.0019333	CDKN2A;PRKCQ;LILRB1;TNFRSF21;TNFSF13B
28	intrinsic apoptotic signaling pathway (GO:0097193)	0.0000589	0.0019333	E2F1;E2F2;TNF;IKBKE;TP73
28	regulation of mononuclear cell proliferation (GO:0032944)	0.0000606	0.0019394	CDKN2A;PRKCQ;LILRB1;TNFRSF21;TNFSF13B
28	activation of cysteine-type endopeptidase activity (GO:0097202)	0.0000637	0.0019894	CDKN2A;TNFSF15;TNFSF10;TNF
28	negative regulation of cytokine secretion (GO:0050710)	0.0000652	0.0019894	LILRB1;TNF;TNFRSF21
28	regulation of leukocyte proliferation (GO:0070663)	0.0000695	0.0020718	CDKN2A;PRKCQ;LILRB1;TNFRSF21;TNFSF13B
28	nuclear division (GO:0000280)	0.0000849	0.0024756	CDC20;CCNB2;CCNF;CKS2;CDC6;PKMYT1
28	negative regulation of cytokine production (GO:0001818)	0.0000879	0.0025084	LILRB1;GATA3;TNF;IKBKE;TNFRSF21
28	placenta development (GO:0001890)	0.0000932	0.0025855	CCNF;E2F7;E2F8
28	regulation of establishment of protein localization (GO:0070201)	0.0000946	0.0025855	CDKN2A;TNFSF15;E2F1;LILRB1;GATA3;TNF;TNFRSF21
28	negative regulation of G1/S transition of mitotic cell cycle (GO:2000134)	0.0001009	0.0026468	CDKN2B;CCND1;E2F7;TP73
28	negative regulation of cell cycle G1/S phase transition (GO:1902807)	0.0001009	0.0026468	CDKN2B;CCND1;E2F7;TP73
28	negative regulation of mitotic cell cycle phase transition (GO:1901991)	0.0001048	0.0026949	CDC20;CDKN2B;CCND1;E2F7;TP73
28	zymogen activation (GO:0031638)	0.0001133	0.0027158	CDKN2A;TNFSF15;TNFSF10;TNF
28	mitotic cell cycle checkpoint (GO:0007093)	0.0001176	0.0027158	CDC20;CDKN2B;CCND1;TP73
28	positive regulation of mitotic cell cycle (GO:0045931)	0.0001176	0.0027158	BTC;CCND1;CDC6;TNF
28	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002822)	0.0001176	0.0027158	PRKCQ;LILRB1;TNF;TNFSF13B
28	negative regulation of phosphorus metabolic process (GO:0010563)	0.0001180	0.0027158	CDKN2B;CDKN2A;PTK6;FOXM1;PKMYT1;TNF;TP73
28	negative regulation of phosphate metabolic process (GO:0045936)	0.0001180	0.0027158	CDKN2B;CDKN2A;PTK6;FOXM1;PKMYT1;TNF;TP73
28	negative regulation of cell cycle phase transition (GO:1901988)	0.0001269	0.0028700	CDC20;CDKN2B;CCND1;E2F7;TP73
28	organelle fission (GO:0048285)	0.0001365	0.0030355	CDC20;CCNB2;CCNF;CKS2;CDC6;PKMYT1
28	apoptotic signaling pathway (GO:0097190)	0.0001411	0.0030862	TNFSF10;E2F1;E2F2;TNF;IKBKE;TP73
28	negative regulation of cellular component organization (GO:0051129)	0.0001459	0.0031380	CDC20;SPI1;CCNF;DNMT3B;TACSTD2;LILRB1;TNF
28	negative regulation of T cell proliferation (GO:0042130)	0.0001483	0.0031389	CDKN2A;LILRB1;TNFRSF21
28	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043280)	0.0001571	0.0032423	CDKN2A;TNFSF15;TNFSF10;TNF
28	regulation of adaptive immune response (GO:0002819)	0.0001626	0.0032423	PRKCQ;LILRB1;TNF;TNFSF13B
28	negative regulation of protein secretion (GO:0050709)	0.0001824	0.0035718	LILRB1;TNF;TNFRSF21
28	regulation of lymphocyte activation (GO:0051249)	0.0001858	0.0035851	CDKN2A;PRKCQ;LILRB1;GATA3;TNFRSF21;TNFSF13B
28	negative regulation of mitotic cell cycle (GO:0045930)	0.0001938	0.0036841	CDC20;CDKN2B;CCND1;E2F7;TP73
28	positive regulation of cysteine-type endopeptidase activity (GO:2001056)	0.0002053	0.0038153	CDKN2A;TNFSF15;TNFSF10;TNF
28	response to drug (GO:0042493)	0.0002169	0.0038692	CCND1;DNMT3B;TNFRSF11B;GATA3;TNF;CCNO
28	regulation of cytokinesis (GO:0032465)	0.0002212	0.0038692	CDC6;E2F7;E2F8
28	intrinsic apoptotic signaling pathway by p53 class mediator (GO:0072332)	0.0002212	0.0038692	E2F1;E2F2;TP73
28	response to ionizing radiation (GO:0010212)	0.0002633	0.0045462	CCND1;DNMT3B;GATA3;TP73
28	positive regulation of endopeptidase activity (GO:0010950)	0.0002714	0.0046236	CDKN2A;TNFSF15;TNFSF10;TNF
28	negative regulation of organelle organization (GO:0010639)	0.0002792	0.0046971	CDC20;SPI1;CCNF;DNMT3B;TACSTD2
28	mitotic nuclear division (GO:0007067)	0.0002959	0.0048108	CDC20;CCNB2;CCNF;CDC6;PKMYT1
28	negative regulation of lymphocyte proliferation (GO:0050672)	0.0002970	0.0048108	CDKN2A;LILRB1;TNFRSF21
28	negative regulation of mononuclear cell proliferation (GO:0032945)	0.0002970	0.0048108	CDKN2A;LILRB1;TNFRSF21
28	regulation of protein transport (GO:0051223)	0.0003128	0.0049625	CDKN2A;TNFSF15;LILRB1;GATA3;TNF;TNFRSF21
28	regulation of B cell proliferation (GO:0030888)	0.0003139	0.0049625	CDKN2A;TNFRSF21;TNFSF13B
28	negative regulation of leukocyte proliferation (GO:0070664)	0.0003496	0.0052214	CDKN2A;LILRB1;TNFRSF21
28	regulation of leukocyte activation (GO:0002694)	0.0003643	0.0052214	CDKN2A;PRKCQ;LILRB1;GATA3;TNFRSF21;TNFSF13B
28	positive regulation of response to DNA damage stimulus (GO:2001022)	0.0003684	0.0052214	CDKN2A;FOXM1;TP73
28	positive regulation of peptidase activity (GO:0010952)	0.0003714	0.0052214	CDKN2A;TNFSF15;TNFSF10;TNF
28	cell cycle G2/M phase transition (GO:0044839)	0.0003714	0.0052214	CCNB2;CDKN2B;FOXM1;PKMYT1
28	G2/M transition of mitotic cell cycle (GO:0000086)	0.0003714	0.0052214	CCNB2;CDKN2B;FOXM1;PKMYT1
28	positive regulation of cytokine biosynthetic process (GO:0042108)	0.0004079	0.0055177	PRKCQ;LTB;TNF
28	cellular response to acid chemical (GO:0071229)	0.0004590	0.0060834	DNMT3B;E2F1;PTK6;TNF
28	reproductive structure development (GO:0048608)	0.0004658	0.0061112	CCNF;TNFSF10;GATA3;E2F7;E2F8
28	regulation of alpha-beta T cell activation (GO:0046634)	0.0004949	0.0063724	PRKCQ;LILRB1;GATA3
28	regulation of organ morphogenesis (GO:2000027)	0.0004954	0.0063724	TACSTD2;TNFRSF11B;GATA3;TNF
28	regulation of cell activation (GO:0050865)	0.0005392	0.0067374	CDKN2A;PRKCQ;LILRB1;GATA3;TNFRSF21;TNFSF13B
28	myeloid cell differentiation (GO:0030099)	0.0005471	0.0067712	CDKN2B;SPI1;GATA3;TNF
28	negative regulation of cell division (GO:0051782)	0.0005674	0.0069567	CDC20;E2F7;E2F8
28	protein secretion (GO:0009306)	0.0005929	0.0070241	LILRB1;GATA3;TNFSF13B
28	negative regulation of transferase activity (GO:0051348)	0.0006376	0.0073385	CDC20;CDKN2B;CDKN2A;PTK6;TP73
28	positive regulation of cytokine secretion (GO:0050715)	0.0006463	0.0073730	TNFSF15;GATA3;TNF
28	regulation of leukocyte apoptotic process (GO:2000106)	0.0007026	0.0077460	CDKN2A;PRKCQ;LILRB1
28	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002824)	0.0007026	0.0077460	PRKCQ;TNF;TNFSF13B
28	immune response-regulating cell surface receptor signaling pathway (GO:0002768)	0.0007214	0.0078870	BTC;NRG4;PRKCQ;LILRB1;GATA3;TNFRSF21
28	negative regulation of T cell activation (GO:0050868)	0.0007619	0.0082614	CDKN2A;LILRB1;TNFRSF21
28	positive regulation of adaptive immune response (GO:0002821)	0.0007927	0.0085253	PRKCQ;TNF;TNFSF13B
28	regulation of chromosome organization (GO:0033044)	0.0008277	0.0088285	CDC20;SPI1;DNMT3B;GATA3
28	hematopoietic or lymphoid organ development (GO:0048534)	0.0008827	0.0092651	CCNB2;CDKN2B;LTB;GATA3
28	DNA damage checkpoint (GO:0000077)	0.0008900	0.0092670	CCND1;E2F1;TP73
28	regulation of interferon-gamma production (GO:0032649)	0.0009588	0.0099052	LILRB1;GATA3;TNF
28	negative regulation of chromosome organization (GO:2001251)	0.0009945	0.0101932	CDC20;SPI1;DNMT3B
28	myeloid leukocyte differentiation (GO:0002573)	0.0011064	0.0110009	SPI1;GATA3;TNF
28	regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043281)	0.0011068	0.0110009	CDKN2A;TNFSF15;TNFSF10;TNF
28	negative regulation of phosphorylation (GO:0042326)	0.0011663	0.0113958	CDKN2B;CDKN2A;PTK6;FOXM1;TP73
28	positive regulation of T cell activation (GO:0050870)	0.0011742	0.0113958	PRKCQ;LILRB1;GATA3;TNFSF13B
28	negative regulation of protein kinase activity (GO:0006469)	0.0011742	0.0113958	CDKN2B;CDKN2A;PTK6;TP73
28	positive regulation of cytokine production (GO:0001819)	0.0011985	0.0113958	TNFSF15;PRKCQ;LTB;GATA3;TNF
28	cellular response to tumor necrosis factor (GO:0071356)	0.0013535	0.0127755	GATA3;TNF;TNFRSF21
28	regulation of cysteine-type endopeptidase activity (GO:2000116)	0.0013681	0.0128213	CDKN2A;TNFSF15;TNFSF10;TNF
28	positive regulation of organelle organization (GO:0010638)	0.0014239	0.0132388	BTC;DNMT3B;TNFSF10;E2F1;TNF
28	DNA damage response, signal transduction by p53 class mediator (GO:0030330)	0.0014430	0.0132388	FOXM1;E2F7;TP73
28	protein processing (GO:0016485)	0.0014730	0.0134207	CDKN2A;TNFSF15;TNFSF10;TNF
28	regulation of B cell activation (GO:0050864)	0.0014890	0.0134732	CDKN2A;TNFRSF21;TNFSF13B
28	negative regulation of kinase activity (GO:0033673)	0.0015001	0.0134802	CDKN2B;CDKN2A;PTK6;TP73
28	regulation of leukocyte differentiation (GO:1902105)	0.0017293	0.0148635	CDKN2A;LILRB1;GATA3;TNF
28	regulation of histone modification (GO:0031056)	0.0017333	0.0148635	SPI1;DNMT3B;GATA3
28	T cell receptor signaling pathway (GO:0050852)	0.0018376	0.0155798	PRKCQ;GATA3;TNFRSF21
28	negative regulation of lymphocyte activation (GO:0051250)	0.0020013	0.0166184	CDKN2A;LILRB1;TNFRSF21
28	regulation of chromatin modification (GO:1903308)	0.0020013	0.0166184	SPI1;DNMT3B;GATA3
28	response to steroid hormone (GO:0048545)	0.0020381	0.0168177	CCND1;TNFRSF11B;TK1;GATA3;TNF
28	protein maturation (GO:0051604)	0.0021172	0.0173613	CDKN2A;TNFSF15;TNFSF10;TNF
28	regulation of cell cycle arrest (GO:0071156)	0.0021738	0.0176050	CCND1;CDKN2A;FOXM1
28	inflammatory response (GO:0006954)	0.0022116	0.0176510	OLR1;PRKCQ;GATA3;TNF;TP73
28	positive regulation of protein secretion (GO:0050714)	0.0022333	0.0176510	TNFSF15;GATA3;TNF
28	signal transduction in response to DNA damage (GO:0042770)	0.0022333	0.0176510	FOXM1;E2F7;TP73
28	hematopoietic progenitor cell differentiation (GO:0002244)	0.0022333	0.0176510	CDKN2B;SPI1;GATA3
28	regulation of chromatin organization (GO:1902275)	0.0022938	0.0179132	SPI1;DNMT3B;GATA3
28	positive regulation of proteolysis (GO:0045862)	0.0023321	0.0181050	CDKN2A;TNFSF15;TNFSF10;TNF
28	regulation of epithelial cell differentiation (GO:0030856)	0.0024178	0.0186596	CDKN2B;CCND1;GATA3
28	response to tumor necrosis factor (GO:0034612)	0.0025459	0.0193075	GATA3;TNF;TNFRSF21
28	positive regulation of protein processing (GO:0010954)	0.0028063	0.0205687	CDKN2A;TNFSF15;TNFSF10;TNF
28	positive regulation of protein maturation (GO:1903319)	0.0028063	0.0205687	CDKN2A;TNFSF15;TNFSF10;TNF
28	positive regulation of lymphocyte activation (GO:0051251)	0.0029344	0.0213884	PRKCQ;LILRB1;GATA3;TNFSF13B
28	regulation of DNA replication (GO:0006275)	0.0030270	0.0218213	CDC6;E2F7;E2F8
28	negative regulation of protein serine/threonine kinase activity (GO:0071901)	0.0030270	0.0218213	CDKN2B;CDKN2A;TP73
28	regulation of neuron differentiation (GO:0045664)	0.0030472	0.0218465	CDC20;DNMT3B;PTK6;GATA3;TP73
28	positive regulation of cell division (GO:0051781)	0.0031741	0.0221510	BTC;CDC6;TNF
28	negative regulation of leukocyte activation (GO:0002695)	0.0031741	0.0221510	CDKN2A;LILRB1;TNFRSF21
28	leukocyte differentiation (GO:0002521)	0.0032956	0.0228427	SPI1;LILRB1;GATA3;TNF
28	negative regulation of protein transport (GO:0051224)	0.0033254	0.0228427	LILRB1;TNF;TNFRSF21
28	positive regulation of DNA metabolic process (GO:0051054)	0.0034811	0.0235135	FOXM1;E2F7;E2F8
28	regulation of response to DNA damage stimulus (GO:2001020)	0.0034811	0.0235135	CDKN2A;FOXM1;TP73
28	positive regulation of protein serine/threonine kinase activity (GO:0071902)	0.0035856	0.0238797	CCND1;TNFSF15;TNF;TP73
28	regulation of epithelial cell proliferation (GO:0050678)	0.0036356	0.0240903	CDKN2B;CCND1;TACSTD2;GATA3
28	antigen receptor-mediated signaling pathway (GO:0050851)	0.0037230	0.0243924	PRKCQ;GATA3;TNFRSF21
28	negative regulation of protein phosphorylation (GO:0001933)	0.0037369	0.0243924	CDKN2B;CDKN2A;PTK6;TP73
28	positive regulation of leukocyte activation (GO:0002696)	0.0038402	0.0249424	PRKCQ;LILRB1;GATA3;TNFSF13B
28	response to glucocorticoid (GO:0051384)	0.0039749	0.0256898	CCND1;TK1;TNF
28	positive regulation of cell activation (GO:0050867)	0.0043858	0.0274784	PRKCQ;LILRB1;GATA3;TNFSF13B
28	negative regulation of secretion by cell (GO:1903531)	0.0044173	0.0274784	LILRB1;TNF;TNFRSF21
28	negative regulation of cell activation (GO:0050866)	0.0044173	0.0274784	CDKN2A;LILRB1;TNFRSF21
28	response to radiation (GO:0009314)	0.0044192	0.0274784	CCND1;DNMT3B;PRKCQ;GATA3;TP73
28	inositol lipid-mediated signaling (GO:0048017)	0.0045093	0.0276837	BTC;NRG4;GATA3
28	phosphatidylinositol-mediated signaling (GO:0048015)	0.0045093	0.0276837	BTC;NRG4;GATA3
28	response to acid chemical (GO:0001101)	0.0045592	0.0276929	DNMT3B;E2F1;PTK6;TNF
28	response to corticosteroid (GO:0031960)	0.0048886	0.0291537	CCND1;TK1;TNF
28	cell cycle arrest (GO:0007050)	0.0048886	0.0291537	CDKN2B;CDKN2A;TP73
28	response to nutrient levels (GO:0031667)	0.0055625	0.0315932	CDKN2B;CCND1;TNFRSF11B;TK1
28	negative regulation of secretion (GO:0051048)	0.0061401	0.0344632	LILRB1;TNF;TNFRSF21
28	epithelial cell differentiation (GO:0030855)	0.0064054	0.0354216	PTK6;CCNO;E2F7;E2F8
28	regulation of myeloid cell differentiation (GO:0045637)	0.0065960	0.0362088	SPI1;LILRB1;TNF
28	negative regulation of immune system process (GO:0002683)	0.0070122	0.0380166	CDKN2A;LILRB1;TNF;TNFRSF21
28	positive regulation of nervous system development (GO:0051962)	0.0071697	0.0385517	CDC20;DNMT3B;PTK6;TP73
28	response to extracellular stimulus (GO:0009991)	0.0071697	0.0385517	CDKN2B;CCND1;TNFRSF11B;TK1
28	cellular response to lipid (GO:0071396)	0.0073295	0.0390904	E2F1;LILRB1;PTK6;TNF
28	response to nutrient (GO:0007584)	0.0074412	0.0395260	CDKN2B;CCND1;TNFRSF11B
28	response to estrogen (GO:0043627)	0.0078223	0.0408877	CCND1;TNFRSF11B;GATA3
28	positive regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043123)	0.0080826	0.0417494	TNFSF10;TNF;IKBKE
28	positive regulation of apoptotic signaling pathway (GO:2001235)	0.0080826	0.0417494	TNFSF10;E2F1;TP73
28	regulation of stress-activated MAPK cascade (GO:0032872)	0.0083480	0.0429512	FOXM1;TNF;TP73
28	regulation of stress-activated protein kinase signaling cascade (GO:0070302)	0.0084826	0.0434733	FOXM1;TNF;TP73
28	regulation of cell adhesion (GO:0030155)	0.0091514	0.0465373	CDKN2A;TACSTD2;PRKCQ;TNF
28	regulation of endopeptidase activity (GO:0052548)	0.0109308	0.0543039	CDKN2A;TNFSF15;TNFSF10;TNF
28	regulation of neuron apoptotic process (GO:0043523)	0.0109684	0.0543039	GATA3;TNF;TP73
28	regulation of apoptotic signaling pathway (GO:2001233)	0.0111413	0.0547468	TNFSF10;E2F1;TNF;TP73
28	response to inorganic substance (GO:0010035)	0.0126890	0.0618885	CCND1;OLR1;TNFRSF11B;TK1
28	regulation of peptidase activity (GO:0052547)	0.0129208	0.0625540	CDKN2A;TNFSF15;TNFSF10;TNF
28	regulation of cell projection organization (GO:0031344)	0.0152593	0.0710118	CDC20;TACSTD2;PTK6;GATA3
28	regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043122)	0.0153173	0.0710118	TNFSF10;TNF;IKBKE
28	negative regulation of growth (GO:0045926)	0.0168869	0.0766631	CDKN2A;PTK6;TNF
28	regulation of cellular response to stress (GO:0080135)	0.0170045	0.0769305	CDKN2A;FOXM1;TNF;TP73
28	regulation of neuron death (GO:1901214)	0.0177044	0.0792771	GATA3;TNF;TP73
28	positive regulation of protein transport (GO:0051222)	0.0189717	0.0814696	TNFSF15;GATA3;TNF
28	Wnt signaling pathway (GO:0016055)	0.0196238	0.0819949	CCND1;CCNE1;GATA3
28	negative regulation of cell development (GO:0010721)	0.0207381	0.0855319	TACSTD2;LILRB1;TP73
28	immune response-activating signal transduction (GO:0002757)	0.0224755	0.0872421	PRKCQ;GATA3;IKBKE;TNFRSF21
28	positive regulation of secretion by cell (GO:1903532)	0.0225925	0.0874376	TNFSF15;GATA3;TNF
28	response to virus (GO:0009615)	0.0233106	0.0888234	LILRB1;GATA3;TNF
28	activation of protein kinase activity (GO:0032147)	0.0237962	0.0888234	TNFSF15;TNF;TP73
28	response to metal ion (GO:0010038)	0.0245349	0.0896653	CCND1;TNFRSF11B;TK1
28	positive regulation of protein kinase activity (GO:0045860)	0.0252166	0.0919005	CCND1;TNFSF15;TNF;TP73
28	regulation of protein catabolic process (GO:0042176)	0.0257937	0.0924255	CDC20;CDC6;TNF
28	humoral immune response (GO:0006959)	0.0265655	0.0924255	GATA3;TNF;TNFRSF21
28	cellular response to cytokine stimulus (GO:0071345)	0.0279634	0.0942261	GATA3;KPNA2;TNF;TNFRSF21
28	positive regulation of secretion (GO:0051047)	0.0292273	0.0946819	TNFSF15;GATA3;TNF
28	response to alcohol (GO:0097305)	0.0295010	0.0946904	CCND1;TK1;GATA3
28	positive regulation of kinase activity (GO:0033674)	0.0296947	0.0946904	CCND1;TNFSF15;TNF;TP73
28	regulation of neuron projection development (GO:0010975)	0.0297761	0.0946904	CDC20;PTK6;GATA3
28	embryo development (GO:0009790)	0.0300525	0.0946904	CCNB2;GATA3;CCNO
28	activation of immune response (GO:0002253)	0.0310847	0.0946904	PRKCQ;GATA3;IKBKE;TNFRSF21
28	positive regulation of neurogenesis (GO:0050769)	0.0320261	0.0961515	DNMT3B;PTK6;TP73
28	Fc-epsilon receptor signaling pathway (GO:0038095)	0.0355645	0.0977605	BTC;NRG4;PRKCQ
28	lymphocyte activation (GO:0046649)	0.0383463	0.1012313	SPI1;LILRB1;GATA3
28	regulation of homeostatic process (GO:0032844)	0.0415648	0.1050733	SPI1;TNFRSF11B;TNF
28	response to light stimulus (GO:0009416)	0.0442354	0.1078753	CCND1;PRKCQ;TP73
28	regulation of cell growth (GO:0001558)	0.0442354	0.1078753	CDKN2A;PRKCQ;FOXM1
28	immune response-activating cell surface receptor signaling pathway (GO:0002429)	0.0449163	0.1084781	PRKCQ;GATA3;TNFRSF21
28	regulation of sequence-specific DNA binding transcription factor activity (GO:0051090)	0.0498292	0.1144198	CDKN2A;PRKCQ;TNF
28	regulation of response to wounding (GO:1903034)	0.0531216	0.1175305	PRKCQ;GATA3;TNF
28	Fc receptor signaling pathway (GO:0038093)	0.0549955	0.1188701	BTC;NRG4;PRKCQ
28	positive regulation of cell development (GO:0010720)	0.0572860	0.1204475	DNMT3B;PTK6;TP73
28	extracellular matrix organization (GO:0030198)	0.0576722	0.1210654	POSTN;TNFRSF11B;TNF
28	extracellular structure organization (GO:0043062)	0.0580596	0.1214407	POSTN;TNFRSF11B;TNF
28	negative regulation of transport (GO:0051051)	0.0584483	0.1214407	LILRB1;TNF;TNFRSF21
28	leukocyte activation (GO:0045321)	0.0632091	0.1250116	SPI1;LILRB1;GATA3
28	regulation of intracellular transport (GO:0032386)	0.0719625	0.1341120	CDKN2A;E2F1;TNF
28	DNA repair (GO:0006281)	0.0758741	0.1371168	FOXM1;CCNO;TP73
28	secretion by cell (GO:0032940)	0.0812346	0.1426771	LILRB1;GATA3;TNFSF13B
28	posttranscriptional regulation of gene expression (GO:0010608)	0.0919577	0.1517592	CDKN2A;E2F1;TNF
28	response to other organism (GO:0051707)	0.1037464	0.1612741	LILRB1;GATA3;TNF
28	transcription from RNA polymerase II promoter (GO:0006366)	0.1078056	0.1654280	SPI1;GATA3;FOXM1
28	coagulation (GO:0050817)	0.1088302	0.1655790	OLR1;PRKCQ;GATA3
28	blood coagulation (GO:0007596)	0.1088302	0.1655790	OLR1;PRKCQ;GATA3
28	chromatin modification (GO:0016568)	0.1103743	0.1674117	SPI1;CDKN2A;DNMT3B
28	hemostasis (GO:0007599)	0.1119271	0.1685974	OLR1;PRKCQ;GATA3
28	Cell cycle Homo sapiens hsa04110	0.0000000	0.0000000	CDC20;CCNB2;CDKN2B;CCND1;CCNE1;CDKN2A;E2F1;E2F2;CDC6;PKMYT1
28	Small cell lung cancer Homo sapiens hsa05222	0.0000000	0.0000001	CDKN2B;CCND1;CCNE1;CKS2;E2F1;E2F2;CKS1B
28	HTLV-I infection Homo sapiens hsa05166	0.0000000	0.0000004	CDC20;CCNB2;CDKN2B;SPI1;CCND1;CDKN2A;E2F1;E2F2;TNF
28	Pathways in cancer Homo sapiens hsa05200	0.0000004	0.0000109	CDKN2B;SPI1;CCND1;CCNE1;CDKN2A;CKS2;E2F1;E2F2;CKS1B
28	p53 signaling pathway Homo sapiens hsa04115	0.0000007	0.0000140	CCNB2;CCND1;CCNE1;CDKN2A;TP73
28	Measles Homo sapiens hsa05162	0.0000010	0.0000159	CCND1;CCNE1;TNFSF10;PRKCQ;IKBKE;TP73
28	Hepatitis B Homo sapiens hsa05161	0.0000015	0.0000206	CCND1;CCNE1;E2F1;E2F2;TNF;IKBKE
28	Bladder cancer Homo sapiens hsa05219	0.0000030	0.0000369	CCND1;CDKN2A;E2F1;E2F2
28	Cytokine-cytokine receptor interaction Homo sapiens hsa04060	0.0000035	0.0000385	TNFSF15;TNFSF10;TNFRSF11B;LTB;TNF;TNFRSF21;TNFSF13B
28	Non-small cell lung cancer Homo sapiens hsa05223	0.0000106	0.0001042	CCND1;CDKN2A;E2F1;E2F2
28	Glioma Homo sapiens hsa05214	0.0000193	0.0001673	CCND1;CDKN2A;E2F1;E2F2
28	Pancreatic cancer Homo sapiens hsa05212	0.0000205	0.0001673	CCND1;CDKN2A;E2F1;E2F2
28	Melanoma Homo sapiens hsa05218	0.0000274	0.0002064	CCND1;CDKN2A;E2F1;E2F2
28	Chronic myeloid leukemia Homo sapiens hsa05220	0.0000306	0.0002139	CCND1;CDKN2A;E2F1;E2F2
28	Prostate cancer Homo sapiens hsa05215	0.0000666	0.0004352	CCND1;CCNE1;E2F1;E2F2
28	NF-kappa B signaling pathway Homo sapiens hsa04064	0.0000791	0.0004805	PRKCQ;LTB;TNF;TNFSF13B
28	MicroRNAs in cancer Homo sapiens hsa05206	0.0000834	0.0004805	CCND1;CCNE1;CDKN2A;DNMT3B;E2F1;E2F2
28	Viral carcinogenesis Homo sapiens hsa05203	0.0001424	0.0007754	CDC20;CDKN2B;CCND1;CCNE1;CDKN2A
28	Oocyte meiosis Homo sapiens hsa04114	0.0002330	0.0012018	CDC20;CCNB2;CCNE1;PKMYT1
28	Osteoclast differentiation Homo sapiens hsa04380	0.0003051	0.0014655	SPI1;TNFRSF11B;LILRB1;TNF
28	FoxO signaling pathway Homo sapiens hsa04068	0.0003140	0.0014655	CCNB2;CDKN2B;CCND1;TNFSF10
28	Influenza A Homo sapiens hsa05164	0.0008827	0.0039322	TNFSF10;KPNA2;TNF;IKBKE
28	Rheumatoid arthritis Homo sapiens hsa05323	0.0013978	0.0059557	LTB;TNF;TNFSF13B
28	Mitotic G1-G1/S phases Homo sapiens R-HSA-453279	0.0000000	0.0000000	CDKN2B;CCND1;CCNE1;CDKN2A;E2F1;E2F2;PTK6;CDC6;PKMYT1;CKS1B
28	Cell Cycle, Mitotic Homo sapiens R-HSA-69278	0.0000000	0.0000000	CDKN2B;CDKN2A;PTK6;CDC6;FOXM1;PKMYT1;CKS1B;CDC20;CCNB2;CCND1;CCNE1;E2F1;E2F2
28	G1 Phase Homo sapiens R-HSA-69236	0.0000000	0.0000000	CDKN2B;CCND1;CDKN2A;E2F1;E2F2;CKS1B
28	Cyclin D associated events in G1 Homo sapiens R-HSA-69231	0.0000000	0.0000000	CDKN2B;CCND1;CDKN2A;E2F1;E2F2;CKS1B
28	Cell Cycle Homo sapiens R-HSA-1640170	0.0000000	0.0000000	CDKN2B;CDKN2A;PTK6;CDC6;FOXM1;PKMYT1;CKS1B;CDC20;CCNB2;CCND1;CCNE1;E2F1;E2F2
28	G1/S Transition Homo sapiens R-HSA-69206	0.0000000	0.0000005	CCND1;CCNE1;E2F1;PTK6;CDC6;PKMYT1;CKS1B
28	PTK6 Regulates Cell Cycle Homo sapiens R-HSA-8849470	0.0000003	0.0000118	CCND1;CCNE1;PTK6
28	Signaling by PTK6 Homo sapiens R-HSA-8848021	0.0000006	0.0000222	BTC;CCND1;CCNE1;NRG4;PTK6
28	Cyclin E associated events during G1/S transition Homo sapiens R-HSA-69202	0.0000007	0.0000222	CCND1;CCNE1;PTK6;PKMYT1;CKS1B
28	Oncogene Induced Senescence Homo sapiens R-HSA-2559585	0.0000011	0.0000327	CDKN2B;CDKN2A;E2F1;E2F2
28	CDC6 association with the ORC:origin complex Homo sapiens R-HSA-68689	0.0000022	0.0000615	E2F1;E2F2;CDC6
28	TNFR2 non-canonical NF-kB pathway Homo sapiens R-HSA-5668541	0.0000035	0.0000835	TNFSF15;TNFRSF11B;LTB;TNF;TNFSF13B
28	TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest Homo sapiens R-HSA-6804116	0.0000039	0.0000835	CCNE1;E2F1;E2F7
28	ERBB2 Activates PTK6 Signaling Homo sapiens R-HSA-8847993	0.0000039	0.0000835	BTC;NRG4;PTK6
28	Signaling by ERBB2 Homo sapiens R-HSA-1227986	0.0000044	0.0000883	BTC;NRG4;MATK;PTK6
28	Association of licensing factors with the pre-replicative complex Homo sapiens R-HSA-69298	0.0000062	0.0001159	E2F1;E2F2;CDC6
28	Polo-like kinase mediated events Homo sapiens R-HSA-156711	0.0000076	0.0001340	CCNB2;PKMYT1;FOXM1
28	G1/S-Specific Transcription Homo sapiens R-HSA-69205	0.0000092	0.0001534	CCNE1;E2F1;CDC6
28	S Phase Homo sapiens R-HSA-69242	0.0000129	0.0001972	CCND1;CCNE1;PTK6;CDC6;CKS1B
28	SCF(Skp2)-mediated degradation of p27/p21 Homo sapiens R-HSA-187577	0.0000131	0.0001972	CCND1;CCNE1;PTK6;CKS1B
28	Cyclin A/B1 associated events during G2/M transition Homo sapiens R-HSA-69273	0.0000206	0.0002952	CCNB2;PKMYT1;FOXM1
28	Cyclin A:Cdk2-associated events at S phase entry Homo sapiens R-HSA-69656	0.0000244	0.0003345	CCND1;CCNE1;PTK6;CKS1B
28	TNFs bind their physiological receptors Homo sapiens R-HSA-5669034	0.0000270	0.0003530	TNFSF15;TNFRSF11B;TNFSF13B
28	G0 and Early G1 Homo sapiens R-HSA-1538133	0.0000306	0.0003838	CCNE1;E2F1;CDC6
28	Cellular Senescence Homo sapiens R-HSA-2559583	0.0000455	0.0005478	CDKN2B;CCNE1;CDKN2A;E2F1;E2F2
28	E2F mediated regulation of DNA replication Homo sapiens R-HSA-113510	0.0000716	0.0007810	CCNE1;E2F1;CDC6
28	Oxidative Stress Induced Senescence Homo sapiens R-HSA-2559580	0.0000727	0.0007810	CDKN2B;CDKN2A;E2F1;E2F2
28	Cell Cycle Checkpoints Homo sapiens R-HSA-69620	0.0000814	0.0008451	CDC20;CCNB2;CCNE1;CDC6;PKMYT1
28	Cytokine Signaling in Immune system Homo sapiens R-HSA-1280215	0.0001197	0.0012006	BTC;NRG4;TNFSF15;TNFRSF11B;LTB;KPNA2;TNF;TNFSF13B
28	TP53 Regulates Transcription of Cell Cycle Genes Homo sapiens R-HSA-6791312	0.0002212	0.0020805	CCNE1;E2F1;E2F7
28	Cellular responses to stress Homo sapiens R-HSA-2262752	0.0002633	0.0024018	CDKN2B;CCNE1;CDKN2A;E2F1;E2F2;TNFRSF21
28	Immune System Homo sapiens R-HSA-168256	0.0002742	0.0024279	CDC20;BTC;NRG4;TNFSF15;PRKCQ;TNFRSF11B;LILRB1;LTB;KPNA2;TNF;IKBKE;TNFSF13B
28	Assembly of the pre-replicative complex Homo sapiens R-HSA-68867	0.0005929	0.0050582	E2F1;E2F2;CDC6
28	Apoptosis Homo sapiens R-HSA-109581	0.0006771	0.0053278	TNFSF10;E2F1;PRKCQ;TP73
28	Programmed Cell Death Homo sapiens R-HSA-5357801	0.0007249	0.0054550	TNFSF10;E2F1;PRKCQ;TP73
28	Regulation of DNA replication Homo sapiens R-HSA-69304	0.0008244	0.0059079	E2F1;E2F2;CDC6
28	Mitotic G2-G2/M phases Homo sapiens R-HSA-453274	0.0008827	0.0060387	CCNB2;E2F1;FOXM1;PKMYT1
28	DNA Replication Pre-Initiation Homo sapiens R-HSA-69002	0.0010682	0.0069901	E2F1;E2F2;CDC6
28	M/G1 Transition Homo sapiens R-HSA-68874	0.0010682	0.0069901	E2F1;E2F2;CDC6
28	Transcriptional Regulation by TP53 Homo sapiens R-HSA-3700989	0.0015774	0.0101018	CCNE1;CDKN2A;E2F1;E2F7;TP73
28	DNA Replication Homo sapiens R-HSA-69306	0.0021738	0.0136315	E2F1;E2F2;CDC6
28	G2/M Checkpoints Homo sapiens R-HSA-69481	0.0059195	0.0336183	CCNB2;CDC6;PKMYT1
28	G2/M Transition Homo sapiens R-HSA-69275	0.0087557	0.0470616	CCNB2;FOXM1;PKMYT1
28	Generic Transcription Pathway Homo sapiens R-HSA-212436	0.0139081	0.0656344	CDKN2B;CCNE1;CDKN2A;E2F1;E2F7;TP73
28	Signal Transduction Homo sapiens R-HSA-162582	0.0139555	0.0656344	CDC20;BTC;CDKN2B;CCND1;CCNE1;NRG4;TNFSF10;MATK;E2F1;PRKCQ;PTK6;TNF
28	Adaptive Immune System Homo sapiens R-HSA-1280218	0.0380162	0.1093307	CDC20;BTC;NRG4;PRKCQ;LILRB1
28	Fc epsilon receptor (FCERI) signaling Homo sapiens R-HSA-2454202	0.0723925	0.1702354	BTC;NRG4;PRKCQ
28	Gastrin-CREB signalling pathway via PKC and MAPK Homo sapiens R-HSA-881907	0.0891048	0.1875563	BTC;NRG4;PRKCQ
28	Gene Expression Homo sapiens R-HSA-74160	0.1010112	0.2013534	CDKN2B;CCNE1;CDKN2A;DNMT3B;E2F1;E2F7;TP73
28	Developmental Biology Homo sapiens R-HSA-1266738	0.1256931	0.2090256	BTC;NRG4;PRKCQ;TNF
28	Axon guidance Homo sapiens R-HSA-422475	0.1317581	0.2137474	BTC;NRG4;PRKCQ
28	Innate Immune System Homo sapiens R-HSA-168249	0.1347240	0.2137474	BTC;NRG4;PRKCQ;IKBKE
28	Hemostasis Homo sapiens R-HSA-109582	0.1527438	0.2291586	OLR1;PRKCQ;GATA3
28	Disease Homo sapiens R-HSA-1643685	0.2617927	0.2907734	BTC;NRG4;KPNA2
28	Signaling by GPCR Homo sapiens R-HSA-372790	0.6218944	0.6345431	BTC;NRG4;PRKCQ
28	Metabolism Homo sapiens R-HSA-1430728	0.6999576	0.7117812	DDAH1;TK1;SLC5A1;TNFRSF21
28	Cyclins and Cell Cycle Regulation Homo sapiens h cellcyclePathway	0.0000000	0.0000001	CDKN2B;CCND1;CDKN2A;CCNE1;E2F1
28	Cell Cycle: G1/S Check Point Homo sapiens h g1Pathway	0.0000000	0.0000001	CDKN2B;CCND1;CDKN2A;CCNE1;E2F1
28	p53 Signaling Pathway Homo sapiens h p53Pathway	0.0000039	0.0000379	CCND1;CCNE1;E2F1
28	Regulation of p27 Phosphorylation during Cell Cycle Progression Homo sapiens h p27Pathway	0.0000039	0.0000379	CCNE1;E2F1;CKS1B
28	Influence of Ras and Rho proteins on G1 to S Transition Homo sapiens h RacCycDPathway	0.0000434	0.0003382	CCND1;CCNE1;E2F1
28	IL-2 Receptor Beta Chain in T cell Activation Homo sapiens h il2rbPathway	0.0002352	0.0012739	CCND1;CCNE1;E2F1
30	positive regulation of cytokine production (GO:0001819)	0.0000003	0.0002161	ZBP1;RIPK3;IL1B;IL18;TNFRSF8;TNFRSF13C;CARD11
30	regulation of T cell proliferation (GO:0042129)	0.0000008	0.0002775	RIPK3;IL1B;IL18;TNFRSF13C;CARD11
30	regulation of T cell activation (GO:0050863)	0.0000013	0.0002775	RIPK3;IL1B;IL18;TNFRSF13C;TNFAIP8L2;CARD11
30	positive regulation of cytokine biosynthetic process (GO:0042108)	0.0000013	0.0002775	IL1B;TNFRSF8;TNFRSF13C;CARD11
30	positive regulation of defense response (GO:0031349)	0.0000018	0.0002937	ZBP1;CASP8;RIPK3;IL1B;ITGB2;IL18
30	positive regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043123)	0.0000033	0.0002996	CASP8;IL1B;IL18;LGALS9;CARD11
30	lymphocyte activation (GO:0046649)	0.0000033	0.0002996	CASP8;RIPK3;CD8A;IL18;CXCR4;CD48
30	regulation of cytokine production (GO:0001817)	0.0000035	0.0002996	ZBP1;RIPK3;IL1B;IL18;TNFRSF8;TNFRSF13C;CARD11
30	regulation of lymphocyte proliferation (GO:0050670)	0.0000035	0.0002996	RIPK3;IL1B;IL18;TNFRSF13C;CARD11
30	regulation of mononuclear cell proliferation (GO:0032944)	0.0000036	0.0002996	RIPK3;IL1B;IL18;TNFRSF13C;CARD11
30	regulation of leukocyte proliferation (GO:0070663)	0.0000042	0.0002996	RIPK3;IL1B;IL18;TNFRSF13C;CARD11
30	regulation of interferon-gamma production (GO:0032649)	0.0000043	0.0002996	RIPK3;IL1B;IL18;TNFRSF13C
30	positive regulation of T cell proliferation (GO:0042102)	0.0000052	0.0003369	IL1B;IL18;TNFRSF13C;CARD11
30	regulation of lymphocyte activation (GO:0051249)	0.0000068	0.0003829	RIPK3;IL1B;IL18;TNFRSF13C;TNFAIP8L2;CARD11
30	regulation of response to wounding (GO:1903034)	0.0000071	0.0003829	TNFRSF12A;PLAU;IL1B;IL18;TNFAIP8L2;KLK8
30	T cell activation (GO:0042110)	0.0000074	0.0003829	CASP8;RIPK3;CD8A;CXCR4;CD48
30	extrinsic apoptotic signaling pathway (GO:0097191)	0.0000079	0.0003829	CASP8;TNFRSF12A;IL1B;BCL2L1
30	regulation of cytokine biosynthetic process (GO:0042035)	0.0000082	0.0003829	IL1B;TNFRSF8;TNFRSF13C;CARD11
30	regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043122)	0.0000105	0.0004488	CASP8;IL1B;IL18;LGALS9;CARD11
30	leukocyte activation (GO:0045321)	0.0000108	0.0004488	CASP8;RIPK3;CD8A;IL18;CXCR4;CD48
30	inflammatory response (GO:0006954)	0.0000113	0.0004488	IL1RN;IL1B;ITGB2;IL18;CXCR4;IL1RAP
30	regulation of leukocyte activation (GO:0002694)	0.0000139	0.0005272	RIPK3;IL1B;IL18;TNFRSF13C;TNFAIP8L2;CARD11
30	positive regulation of lymphocyte proliferation (GO:0050671)	0.0000191	0.0006889	IL1B;IL18;TNFRSF13C;CARD11
30	positive regulation of mononuclear cell proliferation (GO:0032946)	0.0000198	0.0006889	IL1B;IL18;TNFRSF13C;CARD11
30	regulation of cell activation (GO:0050865)	0.0000211	0.0007032	RIPK3;IL1B;IL18;TNFRSF13C;TNFAIP8L2;CARD11
30	positive regulation of leukocyte proliferation (GO:0070665)	0.0000218	0.0007032	IL1B;IL18;TNFRSF13C;CARD11
30	regulation of innate immune response (GO:0045088)	0.0000246	0.0007620	ZBP1;CASP8;RIPK3;ITGB2;USP18
30	taxis (GO:0042330)	0.0000290	0.0008382	PLAU;IL1B;ITGB2;CXCR4;MET
30	chemotaxis (GO:0006935)	0.0000290	0.0008382	PLAU;IL1B;ITGB2;CXCR4;MET
30	positive regulation of interferon-gamma production (GO:0032729)	0.0000519	0.0014471	IL1B;IL18;TNFRSF13C
30	regulation of extrinsic apoptotic signaling pathway (GO:2001236)	0.0000712	0.0017727	CASP8;TNFRSF12A;IL1B;BCL2L1
30	regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001239)	0.0000720	0.0017727	CASP8;IL1B;BCL2L1
30	apoptotic signaling pathway (GO:0097190)	0.0000817	0.0019107	CASP8;RIPK3;TNFRSF12A;IL1B;BCL2L1
30	positive regulation of apoptotic signaling pathway (GO:2001235)	0.0000840	0.0019107	CASP8;RIPK3;TNFRSF12A;BCL2L1
30	cellular response to mechanical stimulus (GO:0071260)	0.0001109	0.0024419	CASP8;IL1B;TNFRSF8
30	regulation of apoptotic signaling pathway (GO:2001233)	0.0001219	0.0025877	CASP8;RIPK3;TNFRSF12A;IL1B;BCL2L1
30	positive regulation of T cell activation (GO:0050870)	0.0001324	0.0026934	IL1B;IL18;TNFRSF13C;CARD11
30	positive regulation of innate immune response (GO:0045089)	0.0001352	0.0026934	ZBP1;CASP8;RIPK3;ITGB2
30	positive regulation of MAP kinase activity (GO:0043406)	0.0001553	0.0029548	IL1RN;IL1B;CXCR4;MET
30	protein heterooligomerization (GO:0051291)	0.0001949	0.0035705	CASP8;RIPK3;PCBD1
30	regulation of cellular response to stress (GO:0080135)	0.0002198	0.0039138	IL1RN;IL1B;KLK8;MET;BCL2L1
30	leukocyte migration (GO:0050900)	0.0002627	0.0044871	IL1B;ITGB2;CXCR4;CD48
30	response to lipopolysaccharide (GO:0032496)	0.0002717	0.0045474	IL1RN;CASP8;IL1B;IL18
30	cellular response to abiotic stimulus (GO:0071214)	0.0002902	0.0045836	CASP8;IL1B;TNFRSF8;BCL2L1
30	regulation of cytokine-mediated signaling pathway (GO:0001959)	0.0003120	0.0048365	ZBP1;IL1RN;USP18
30	toll-like receptor 4 signaling pathway (GO:0034142)	0.0003318	0.0049586	CASP8;RIPK3;ITGB2
30	positive regulation of lymphocyte activation (GO:0051251)	0.0003461	0.0049940	IL1B;IL18;TNFRSF13C;CARD11
30	response to molecule of bacterial origin (GO:0002237)	0.0003461	0.0049940	IL1RN;CASP8;IL1B;IL18
30	leukocyte chemotaxis (GO:0030595)	0.0003628	0.0051471	IL1B;ITGB2;CXCR4
30	regulation of response to cytokine stimulus (GO:0060759)	0.0003736	0.0052114	ZBP1;IL1RN;USP18
30	positive regulation of protein kinase activity (GO:0045860)	0.0003840	0.0052691	IL1RN;RIPK3;IL1B;CXCR4;MET
30	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002822)	0.0003957	0.0052765	RIPK3;IL1B;TNFRSF13C
30	activation of protein kinase activity (GO:0032147)	0.0003972	0.0052765	RIPK3;IL1B;CXCR4;MET
30	positive regulation of protein serine/threonine kinase activity (GO:0071902)	0.0004278	0.0055255	IL1RN;IL1B;CXCR4;MET
30	positive regulation of leukocyte activation (GO:0002696)	0.0004600	0.0058341	IL1B;IL18;TNFRSF13C;CARD11
30	positive regulation of kinase activity (GO:0033674)	0.0004855	0.0059753	IL1RN;RIPK3;IL1B;CXCR4;MET
30	regulation of adaptive immune response (GO:0002819)	0.0005057	0.0061343	RIPK3;IL1B;TNFRSF13C
30	positive regulation of cell activation (GO:0050867)	0.0005297	0.0063317	IL1B;IL18;TNFRSF13C;CARD11
30	regulation of MAP kinase activity (GO:0043405)	0.0005371	0.0063317	IL1RN;IL1B;CXCR4;MET
30	toll-like receptor signaling pathway (GO:0002224)	0.0006490	0.0074435	CASP8;RIPK3;ITGB2
30	positive regulation of NF-kappaB transcription factor activity (GO:0051092)	0.0007128	0.0080624	RIPK3;IL1B;CARD11
30	activation of MAPK activity (GO:0000187)	0.0008339	0.0090648	IL1B;CXCR4;MET
30	negative regulation of response to wounding (GO:1903035)	0.0009280	0.0097089	PLAU;TNFAIP8L2;KLK8
30	pattern recognition receptor signaling pathway (GO:0002221)	0.0010079	0.0104147	CASP8;RIPK3;ITGB2
30	innate immune response-activating signal transduction (GO:0002758)	0.0010494	0.0107117	CASP8;RIPK3;ITGB2
30	regulation of cell adhesion (GO:0030155)	0.0011649	0.0109552	IL1RN;PLAU;IL1B;IL18
30	activation of innate immune response (GO:0002218)	0.0012033	0.0111907	CASP8;RIPK3;ITGB2
30	cytokine-mediated signaling pathway (GO:0019221)	0.0012436	0.0114298	IL1B;CXCR4;IL1RAP;USP18
30	cell chemotaxis (GO:0060326)	0.0012973	0.0114298	IL1B;ITGB2;CXCR4
30	response to mechanical stimulus (GO:0009612)	0.0018667	0.0147303	CASP8;IL1B;TNFRSF8
30	positive regulation of MAPK cascade (GO:0043410)	0.0021080	0.0160401	IL1RN;IL1B;CXCR4;MET
30	cellular response to external stimulus (GO:0071496)	0.0021516	0.0160795	CASP8;IL1B;TNFRSF8
30	regulation of protein serine/threonine kinase activity (GO:0071900)	0.0025435	0.0185125	IL1RN;IL1B;CXCR4;MET
30	positive regulation of response to external stimulus (GO:0032103)	0.0027222	0.0193090	IL1B;IL18;MET
30	immune response-activating signal transduction (GO:0002757)	0.0031132	0.0211852	CASP8;RIPK3;ITGB2;CARD11
30	regulation of establishment of protein localization (GO:0070201)	0.0031643	0.0213593	CASP8;IL1B;IL18;BCL2L1
30	positive regulation of sequence-specific DNA binding transcription factor activity (GO:0051091)	0.0032486	0.0217526	RIPK3;IL1B;CARD11
30	negative regulation of response to external stimulus (GO:0032102)	0.0032915	0.0218650	PLAU;TNFAIP8L2;KLK8
30	positive regulation of intracellular transport (GO:0032388)	0.0033783	0.0222651	CASP8;IL1B;IL18
30	response to other organism (GO:0051707)	0.0037075	0.0242436	CD8A;CXCR4;ROMO1;BCL2L1
30	cellular process involved in reproduction in multicellular organism (GO:0022412)	0.0038812	0.0251826	IL1B;CXCR4;BCL2L1
30	cellular response to cytokine stimulus (GO:0071345)	0.0039715	0.0255703	IL1B;CXCR4;IL1RAP;USP18
30	angiogenesis (GO:0001525)	0.0042742	0.0273089	CASP8;TNFRSF12A;IL18
30	activation of immune response (GO:0002253)	0.0044720	0.0279331	CASP8;RIPK3;ITGB2;CARD11
30	regulation of inflammatory response (GO:0050727)	0.0048529	0.0296486	IL1B;IL18;TNFAIP8L2
30	response to virus (GO:0009615)	0.0050185	0.0299111	CD8A;CXCR4;BCL2L1
30	leukocyte differentiation (GO:0002521)	0.0050745	0.0299111	CASP8;RIPK3;CD8A
30	cellular response to organic cyclic compound (GO:0071407)	0.0076311	0.0394273	CASP8;IL1B;IL18
30	regulation of sequence-specific DNA binding transcription factor activity (GO:0051090)	0.0114628	0.0533022	RIPK3;IL1B;CARD11
30	negative regulation of intracellular signal transduction (GO:1902532)	0.0121130	0.0535169	CASP8;IL1B;BCL2L1
30	single-organism behavior (GO:0044708)	0.0137796	0.0554617	IL1RN;KLK8;MET
30	protein oligomerization (GO:0051259)	0.0141899	0.0560261	CASP8;RIPK3;PCBD1
30	regulation of intracellular transport (GO:0032386)	0.0172579	0.0614676	CASP8;IL1B;IL18
30	cellular component morphogenesis (GO:0032989)	0.0226439	0.0701883	KLK8;MET;BCL2L1
30	coagulation (GO:0050817)	0.0276359	0.0751221	PLAU;ITGB2;CD48
30	blood coagulation (GO:0007596)	0.0276359	0.0751221	PLAU;ITGB2;CD48
30	hemostasis (GO:0007599)	0.0285466	0.0753980	PLAU;ITGB2;CD48
30	behavior (GO:0007610)	0.0310535	0.0769699	IL1RN;KLK8;MET
30	Cytokine-cytokine receptor interaction Homo sapiens hsa04060	0.0000000	0.0000002	TNFRSF12A;IL1B;IL18;CXCR4;TNFRSF8;IL1RAP;TNFRSF13C;MET
30	NF-kappa B signaling pathway Homo sapiens hsa04064	0.0000002	0.0000065	PLAU;IL1B;TNFRSF13C;CARD11;BCL2L1
30	Malaria Homo sapiens hsa05144	0.0000006	0.0000154	IL1B;ITGB2;IL18;MET
30	Legionellosis Homo sapiens hsa05134	0.0000010	0.0000185	CASP8;IL1B;ITGB2;IL18
30	Cytosolic DNA-sensing pathway Homo sapiens hsa04623	0.0000018	0.0000273	ZBP1;RIPK3;IL1B;IL18
30	NOD-like receptor signaling pathway Homo sapiens hsa04621	0.0000684	0.0008430	CASP8;IL1B;IL18
30	Tuberculosis Homo sapiens hsa05152	0.0001051	0.0011109	CASP8;IL1B;ITGB2;IL18
30	Rheumatoid arthritis Homo sapiens hsa05323	0.0002661	0.0024612	IL1B;ITGB2;IL18
30	TNF signaling pathway Homo sapiens hsa04668	0.0004797	0.0039446	CASP8;RIPK3;IL1B
30	Transcriptional misregulation in cancer Homo sapiens hsa05202	0.0019902	0.0113488	PLAU;MET;BCL2L1
30	Pathways in cancer Homo sapiens hsa05200	0.0021471	0.0113488	CASP8;CXCR4;MET;BCL2L1
30	HTLV-I infection Homo sapiens hsa05166	0.0054770	0.0202648	ITGB2;TNFRSF13C;BCL2L1
30	Immune System Homo sapiens R-HSA-168256	0.0000000	0.0000000	ZBP1;IL1RN;RIPK3;TNFRSF12A;ITGB2;IL18;IL1RAP;TNFRSF13C;USP18;CASP8;CD8A;IL1B;LGALS9;CARD11;BCL2L1
30	Cytokine Signaling in Immune system Homo sapiens R-HSA-1280215	0.0000015	0.0000688	IL1RN;TNFRSF12A;IL1B;IL18;IL1RAP;TNFRSF13C;LGALS9;USP18
30	Interleukin-1 signaling Homo sapiens R-HSA-446652	0.0000313	0.0007359	IL1RN;IL1B;IL1RAP
30	Innate Immune System Homo sapiens R-HSA-168249	0.0000955	0.0012829	ZBP1;CASP8;RIPK3;IL1B;ITGB2;CARD11;BCL2L1
30	Signaling by Interleukins Homo sapiens R-HSA-449147	0.0001911	0.0021062	IL1RN;IL1B;IL18;IL1RAP;LGALS9
30	CLEC7A (Dectin-1) signaling Homo sapiens R-HSA-5607764	0.0003523	0.0027594	CASP8;IL1B;CARD11
30	Toll Like Receptor 4 (TLR4) Cascade Homo sapiens R-HSA-166016	0.0006490	0.0039043	CASP8;RIPK3;ITGB2
30	C-type lectin receptors (CLRs) Homo sapiens R-HSA-5621481	0.0006646	0.0039043	CASP8;IL1B;CARD11
30	Toll-Like Receptors Cascades Homo sapiens R-HSA-168898	0.0009674	0.0053491	CASP8;RIPK3;ITGB2
30	Programmed Cell Death Homo sapiens R-HSA-5357801	0.0015793	0.0078134	CASP8;RIPK3;BCL2L1
30	Hemostasis Homo sapiens R-HSA-109582	0.0410911	0.0713927	PLAU;ITGB2;CD48
30	Adaptive Immune System Homo sapiens R-HSA-1280218	0.0892464	0.1276923	CD8A;ITGB2;CARD11
30	Signal transduction through IL1R Homo sapiens h il1rPathway	0.0000170	0.0004593	IL1RN;IL1B;IL1RAP
32	organic anion transport (GO:0015711)	0.0000989	0.0482254	CA12;CA9;EMB;SLC16A3;FOLR1
32	anion transport (GO:0006820)	0.0003990	0.0482254	CA12;CA9;EMB;SLC16A3;FOLR1
32	response to alcohol (GO:0097305)	0.0006249	0.0482254	NQO1;SPP1;CA9;BID
32	positive regulation of apoptotic signaling pathway (GO:2001235)	0.0018118	0.0680280	GZMB;BID;CTSC
32	response to steroid hormone (GO:0048545)	0.0018799	0.0680280	NQO1;SPP1;CA9;BID
32	regulation of establishment of protein localization (GO:0070201)	0.0036075	0.0896093	ERBB4;GZMB;BID;NKD2
32	positive regulation of intracellular transport (GO:0032388)	0.0037383	0.0896093	ERBB4;GZMB;BID
32	carboxylic acid transport (GO:0046942)	0.0040858	0.0896093	EMB;SLC16A3;FOLR1
32	leukocyte migration (GO:0050900)	0.0041886	0.0896093	SPP1;L1CAM;SLC16A3
32	organic acid transport (GO:0015849)	0.0041886	0.0896093	EMB;SLC16A3;FOLR1
32	positive regulation of proteolysis (GO:0045862)	0.0042930	0.0896093	BID;CTSC;NKD2
32	coagulation (GO:0050817)	0.0045566	0.0896093	SERPINA1;KIF4A;L1CAM;SLC16A3
32	blood coagulation (GO:0007596)	0.0045566	0.0896093	SERPINA1;KIF4A;L1CAM;SLC16A3
32	hemostasis (GO:0007599)	0.0047649	0.0896093	SERPINA1;KIF4A;L1CAM;SLC16A3
32	positive regulation of protein processing (GO:0010954)	0.0049525	0.0896093	BID;CTSC;NKD2
32	positive regulation of protein maturation (GO:1903319)	0.0049525	0.0896093	BID;CTSC;NKD2
32	nervous system development (GO:0007399)	0.0073586	0.1253129	ERBB4;NINJ2;L1CAM
32	positive regulation of organelle organization (GO:0010638)	0.0128296	0.1554367	TGFA;GZMB;BID
32	regulation of endopeptidase activity (GO:0052548)	0.0142911	0.1554367	SERPINA1;RPS6KA1;BID
32	response to drug (GO:0042493)	0.0142911	0.1554367	MMP7;TGFA;CA9
32	negative regulation of hydrolase activity (GO:0051346)	0.0142911	0.1554367	SERPINA1;GZMA;RPS6KA1
32	regulation of apoptotic signaling pathway (GO:2001233)	0.0145073	0.1554367	GZMB;BID;CTSC
32	neuron projection guidance (GO:0097485)	0.0157302	0.1554367	KIF4A;RPS6KA1;L1CAM
32	axon guidance (GO:0007411)	0.0157302	0.1554367	KIF4A;RPS6KA1;L1CAM
32	regulation of peptidase activity (GO:0052547)	0.0163049	0.1554367	SERPINA1;RPS6KA1;BID
32	regulation of intracellular transport (GO:0032386)	0.0189740	0.1554367	ERBB4;GZMB;BID
32	synaptic transmission (GO:0007268)	0.0244178	0.1554367	NQO1;RPS6KA1;CNIH2
32	Apoptosis Homo sapiens hsa04210	0.0010735	0.0241542	GZMB;BID;CTSC
32	Cargo concentration in the ER Homo sapiens R-HSA-5694530	0.0000000	0.0000002	SERPINA1;TGFA;CNIH2;FOLR1;CTSC
32	COPII (Coat Protein 2) Mediated Vesicle Transport Homo sapiens R-HSA-204005	0.0000000	0.0000042	SERPINA1;TGFA;CNIH2;FOLR1;CTSC
32	ER to Golgi Anterograde Transport Homo sapiens R-HSA-199977	0.0000012	0.0000752	SERPINA1;TGFA;CNIH2;FOLR1;CTSC
32	Transport to the Golgi and subsequent modification Homo sapiens R-HSA-948021	0.0000033	0.0001605	SERPINA1;TGFA;CNIH2;FOLR1;CTSC
32	Recycling pathway of L1 Homo sapiens R-HSA-437239	0.0000070	0.0002690	KIF4A;RPS6KA1;L1CAM
32	Membrane Trafficking Homo sapiens R-HSA-199991	0.0000261	0.0007784	SERPINA1;KIF4A;TGFA;CNIH2;FOLR1;CTSC
32	Asparagine N-linked glycosylation Homo sapiens R-HSA-446203	0.0000323	0.0007784	SERPINA1;TGFA;CNIH2;FOLR1;CTSC
32	Vesicle-mediated transport Homo sapiens R-HSA-5653656	0.0000631	0.0013530	SERPINA1;KIF4A;TGFA;CNIH2;FOLR1;CTSC
32	L1CAM interactions Homo sapiens R-HSA-373760	0.0003577	0.0057527	KIF4A;RPS6KA1;L1CAM
32	Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Homo sapiens R-HSA-425366	0.0004152	0.0061635	EMB;SLC16A3;CP
32	Post-translational protein modification Homo sapiens R-HSA-597592	0.0008328	0.0107153	SERPINA1;TGFA;CNIH2;FOLR1;CTSC
32	Developmental Biology Homo sapiens R-HSA-1266738	0.0050151	0.0569363	MAFB;ERBB4;KIF4A;RPS6KA1;L1CAM
32	Axon guidance Homo sapiens R-HSA-422475	0.0061931	0.0664043	ERBB4;KIF4A;RPS6KA1;L1CAM
32	SLC-mediated transmembrane transport Homo sapiens R-HSA-425407	0.0067203	0.0682637	EMB;SLC16A3;CP
32	Hemostasis Homo sapiens R-HSA-109582	0.0078838	0.0760785	SERPINA1;KIF4A;L1CAM;SLC16A3
32	Metabolism of proteins Homo sapiens R-HSA-392499	0.0179220	0.1115792	SERPINA1;TGFA;CNIH2;FOLR1;CTSC
32	Transmembrane transport of small molecules Homo sapiens R-HSA-382551	0.0537906	0.1832509	EMB;SLC16A3;CP
32	Immune System Homo sapiens R-HSA-168256	0.0691053	0.2048893	ERBB4;KIF4A;RPS6KA1;IRF6;CTSC
32	Adaptive Immune System Homo sapiens R-HSA-1280218	0.0968569	0.2465707	ERBB4;KIF4A;CTSC
32	Signal Transduction Homo sapiens R-HSA-162582	0.2827384	0.3896398	RTKN;ERBB4;RPS6KA1;SPP1;GZMB
32	Metabolism Homo sapiens R-HSA-1430728	0.2977192	0.3896398	CA12;NQO1;CA9;SLC16A3
33	regulation of bone mineralization (GO:0030500)	0.0000007	0.0001189	FBN2;GREM1;BMP7
33	regulation of biomineral tissue development (GO:0070167)	0.0000009	0.0001189	FBN2;GREM1;BMP7
33	extracellular matrix organization (GO:0030198)	0.0000015	0.0001189	FBN2;GREM1;MFAP5;BMP7
33	extracellular structure organization (GO:0043062)	0.0000015	0.0001189	FBN2;GREM1;MFAP5;BMP7
33	regulation of ossification (GO:0030278)	0.0000125	0.0007887	FBN2;GREM1;BMP7
33	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090092)	0.0000155	0.0008167	FBN2;GREM1;BMP7
33	Elastic fibre formation Homo sapiens R-HSA-1566948	0.0000000	0.0000000	FBN2;MFAP5;FBN3;BMP7
33	Extracellular matrix organization Homo sapiens R-HSA-1474244	0.0000006	0.0000009	FBN2;MFAP5;FBN3;BMP7
35	leukocyte activation (GO:0045321)	0.0000523	0.0052397	TYROBP;CADM1;MICB;ULBP3
35	complement activation, classical pathway (GO:0006958)	0.0001088	0.0052397	C1QB;C1QA;C1QC
35	complement activation (GO:0006956)	0.0001367	0.0052397	C1QB;C1QA;C1QC
35	activation of immune response (GO:0002253)	0.0001471	0.0052397	C1QB;C1QA;C1QC;MICB
35	protein activation cascade (GO:0072376)	0.0001910	0.0052946	C1QB;C1QA;C1QC
35	humoral immune response (GO:0006959)	0.0004530	0.0087878	C1QB;C1QA;C1QC
35	lymphocyte activation (GO:0046649)	0.0006910	0.0116267	CADM1;MICB;ULBP3
35	Natural killer cell mediated cytotoxicity Homo sapiens hsa04650	0.0000009	0.0000085	TYROBP;HCST;MICB;ULBP3
35	Prion diseases Homo sapiens hsa05020	0.0000011	0.0000085	C1QB;C1QA;C1QC
35	Staphylococcus aureus infection Homo sapiens hsa05150	0.0000045	0.0000240	C1QB;C1QA;C1QC
35	Pertussis Homo sapiens hsa05133	0.0000109	0.0000407	C1QB;C1QA;C1QC
35	Complement and coagulation cascades Homo sapiens hsa04610	0.0000127	0.0000407	C1QB;C1QA;C1QC
35	Chagas disease (American trypanosomiasis) Homo sapiens hsa05142	0.0000290	0.0000774	C1QB;C1QA;C1QC
35	Systemic lupus erythematosus Homo sapiens hsa05322	0.0000633	0.0001446	C1QB;C1QA;C1QC
35	Cell adhesion molecules (CAMs) Homo sapiens hsa04514	0.0000736	0.0001471	CADM3;CADM1;SELL
35	Immune System Homo sapiens R-HSA-168256	0.0000000	0.0000012	C1QB;C1QA;TYROBP;SELL;FGF18;HCST;C1QC;MICB;ULBP3
35	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Homo sapiens R-HSA-198933	0.0000000	0.0000012	TYROBP;SELL;HCST;MICB;ULBP3
35	Classical antibody-mediated complement activation Homo sapiens R-HSA-173623	0.0000020	0.0000672	C1QB;C1QA;C1QC
35	Adaptive Immune System Homo sapiens R-HSA-1280218	0.0000023	0.0000672	TYROBP;SELL;FGF18;HCST;MICB;ULBP3
35	Creation of C4 and C2 activators Homo sapiens R-HSA-166786	0.0000030	0.0000706	C1QB;C1QA;C1QC
35	Initial triggering of complement Homo sapiens R-HSA-166663	0.0000050	0.0000983	C1QB;C1QA;C1QC
35	Complement cascade Homo sapiens R-HSA-166658	0.0000132	0.0001948	C1QB;C1QA;C1QC
35	Cell-Cell communication Homo sapiens R-HSA-1500931	0.0000579	0.0007586	CADM3;TYROBP;CADM1
35	Innate Immune System Homo sapiens R-HSA-168249	0.0000660	0.0007791	C1QB;C1QA;TYROBP;FGF18;C1QC
35	Classical Complement Pathway Homo sapiens h classicPathway	0.0000001	0.0000001	C1QB;C1QA;C1QC
36	leukocyte migration (GO:0050900)	0.0000050	0.0030995	RET;GRB7;SLC7A7;PTPN6;SLC7A11
36	peptidyl-tyrosine phosphorylation (GO:0018108)	0.0000254	0.0052383	RET;ERBB3;PTPN6;FGFR3
36	peptidyl-tyrosine modification (GO:0018212)	0.0000267	0.0052383	RET;ERBB3;PTPN6;FGFR3
36	MAPK cascade (GO:0000165)	0.0000393	0.0052383	RET;DOK5;NRTN;FGFR3
36	cellular response to retinoic acid (GO:0071300)	0.0000481	0.0052383	RET;MUC1;WNT2
36	regulation of peptidyl-tyrosine phosphorylation (GO:0050730)	0.0000594	0.0052383	ERBB3;CBLC;PTPN6;FGFR3
36	signal transduction by phosphorylation (GO:0023014)	0.0000769	0.0059341	RET;DOK5;NRTN;FGFR3
36	epithelium development (GO:0060429)	0.0001917	0.0107520	RET;EPCAM;FGFR3;WNT2
36	response to retinoic acid (GO:0032526)	0.0002717	0.0139717	RET;MUC1;WNT2
36	regulation of cell adhesion (GO:0030155)	0.0005382	0.0236616	RET;ERBB3;EPCAM;PTPN6
36	cytokine-mediated signaling pathway (GO:0019221)	0.0005752	0.0236616	IL2RA;IL2RB;PTPN6;CSF2RA
36	cellular response to acid chemical (GO:0071229)	0.0006185	0.0237219	RET;MUC1;WNT2
36	response to wounding (GO:0009611)	0.0008956	0.0247015	ERBB3;CSPG5;FGFR3
36	epidermal growth factor receptor signaling pathway (GO:0007173)	0.0013590	0.0279502	GRB7;ERBB3;FGFR3
36	ERBB signaling pathway (GO:0038127)	0.0014205	0.0282728	GRB7;ERBB3;FGFR3
36	regulation of leukocyte differentiation (GO:1902105)	0.0017307	0.0292155	IL2RA;PTPN6;LILRB4
36	cellular response to cytokine stimulus (GO:0071345)	0.0018845	0.0292155	IL2RA;IL2RB;PTPN6;CSF2RA
36	coagulation (GO:0050817)	0.0018991	0.0292155	GRB7;SLC7A7;PTPN6;SLC7A11
36	blood coagulation (GO:0007596)	0.0018991	0.0292155	GRB7;SLC7A7;PTPN6;SLC7A11
36	hemostasis (GO:0007599)	0.0019887	0.0292155	GRB7;SLC7A7;PTPN6;SLC7A11
36	single organismal cell-cell adhesion (GO:0016337)	0.0023841	0.0319774	RET;PTPN6;SLC7A11
36	single organism cell adhesion (GO:0098602)	0.0031386	0.0390382	RET;PTPN6;SLC7A11
36	response to acid chemical (GO:0001101)	0.0037147	0.0440767	RET;MUC1;WNT2
36	nervous system development (GO:0007399)	0.0037910	0.0441329	DOK5;CSPG5;NRTN
36	negative regulation of immune system process (GO:0002683)	0.0052369	0.0538525	IL2RA;PTPN6;LILRB4
36	cellular response to lipid (GO:0071396)	0.0054260	0.0548824	RET;MUC1;WNT2
36	negative regulation of intracellular signal transduction (GO:1902532)	0.0069764	0.0672564	MUC1;CBLC;PTPN6
36	regulation of mitotic cell cycle (GO:0007346)	0.0098226	0.0706041	MUC1;PTPN6;FGFR3
36	immune response-regulating cell surface receptor signaling pathway (GO:0002768)	0.0138379	0.0733707	ERBB3;PTPN6;FGFR3
36	regulation of cell cycle process (GO:0010564)	0.0171238	0.0733707	MUC1;PTPN6;FGFR3
36	Endocytosis Homo sapiens hsa04144	0.0000004	0.0000138	RET;ERBB3;IL2RA;IL2RB;CBLC;FGFR3
36	Jak-STAT signaling pathway Homo sapiens hsa04630	0.0000295	0.0005463	IL2RA;IL2RB;PTPN6;CSF2RA
36	Pathways in cancer Homo sapiens hsa05200	0.0000753	0.0007255	RET;CBLC;CSF2RA;FGFR3;WNT2
36	Proteoglycans in cancer Homo sapiens hsa05205	0.0000784	0.0007255	ERBB3;CBLC;PTPN6;WNT2
36	HTLV-I infection Homo sapiens hsa05166	0.0031045	0.0176945	IL2RA;IL2RB;WNT2
36	Cytokine-cytokine receptor interaction Homo sapiens hsa04060	0.0033476	0.0176945	IL2RA;IL2RB;CSF2RA
36	PI3K-Akt signaling pathway Homo sapiens hsa04151	0.0067560	0.0227246	IL2RA;IL2RB;FGFR3
36	Signaling by SCF-KIT Homo sapiens R-HSA-1433557	0.0000000	0.0000000	RET;GRB7;ERBB3;IL2RA;IL2RB;NRTN;PTPN6;CSF2RA;FGFR3
36	Interleukin receptor SHC signaling Homo sapiens R-HSA-912526	0.0000000	0.0000000	RET;ERBB3;IL2RA;IL2RB;NRTN;PTPN6;CSF2RA;FGFR3
36	Interleukin-2 signaling Homo sapiens R-HSA-451927	0.0000000	0.0000000	RET;ERBB3;IL2RA;IL2RB;NRTN;PTPN6;CSF2RA;FGFR3
36	Interleukin-3, 5 and GM-CSF signaling Homo sapiens R-HSA-512988	0.0000000	0.0000000	RET;ERBB3;IL2RA;IL2RB;NRTN;PTPN6;CSF2RA;FGFR3
36	Downstream signal transduction Homo sapiens R-HSA-186763	0.0000000	0.0000001	RET;GRB7;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Signaling by PDGF Homo sapiens R-HSA-186797	0.0000000	0.0000001	RET;GRB7;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	GRB2 events in EGFR signaling Homo sapiens R-HSA-179812	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	SHC1 events in EGFR signaling Homo sapiens R-HSA-180336	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	SOS-mediated signalling Homo sapiens R-HSA-112412	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	SHC1 events in ERBB4 signaling Homo sapiens R-HSA-1250347	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	RAF/MAP kinase cascade Homo sapiens R-HSA-5673001	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	FRS-mediated FGFR2 signaling Homo sapiens R-HSA-5654700	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	FRS-mediated FGFR4 signaling Homo sapiens R-HSA-5654712	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	FRS-mediated FGFR3 signaling Homo sapiens R-HSA-5654706	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	FRS-mediated FGFR1 signaling Homo sapiens R-HSA-5654693	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	ARMS-mediated activation Homo sapiens R-HSA-170984	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Signalling to p38 via RIT and RIN Homo sapiens R-HSA-187706	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Frs2-mediated activation Homo sapiens R-HSA-170968	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	MAPK1/MAPK3 signaling Homo sapiens R-HSA-5684996	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Prolonged ERK activation events Homo sapiens R-HSA-169893	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Signaling by Leptin Homo sapiens R-HSA-2586552	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Signaling by Interleukins Homo sapiens R-HSA-449147	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;PTPN6;CSF2RA;FGFR3
36	Signalling to RAS Homo sapiens R-HSA-167044	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	VEGFR2 mediated cell proliferation Homo sapiens R-HSA-5218921	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Signalling to ERKs Homo sapiens R-HSA-187687	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	NCAM signaling for neurite out-growth Homo sapiens R-HSA-375165	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	IRS-mediated signalling Homo sapiens R-HSA-112399	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	MAPK family signaling cascades Homo sapiens R-HSA-5683057	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Insulin receptor signalling cascade Homo sapiens R-HSA-74751	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	IGF1R signaling cascade Homo sapiens R-HSA-2428924	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) Homo sapiens R-HSA-2404192	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	IRS-related events triggered by IGF1R Homo sapiens R-HSA-2428928	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	FCERI mediated MAPK activation Homo sapiens R-HSA-2871796	0.0000000	0.0000001	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Signaling by Insulin receptor Homo sapiens R-HSA-74752	0.0000000	0.0000002	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	VEGFA-VEGFR2 Pathway Homo sapiens R-HSA-4420097	0.0000000	0.0000002	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Signaling by VEGF Homo sapiens R-HSA-194138	0.0000001	0.0000003	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Downstream signaling of activated FGFR2 Homo sapiens R-HSA-5654696	0.0000001	0.0000003	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Downstream signaling of activated FGFR4 Homo sapiens R-HSA-5654716	0.0000001	0.0000003	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Downstream signaling of activated FGFR3 Homo sapiens R-HSA-5654708	0.0000001	0.0000003	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Signaling by ERBB4 Homo sapiens R-HSA-1236394	0.0000001	0.0000003	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Signaling by FGFR4 Homo sapiens R-HSA-5654743	0.0000001	0.0000003	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Downstream signaling of activated FGFR1 Homo sapiens R-HSA-5654687	0.0000001	0.0000003	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Signaling by FGFR3 Homo sapiens R-HSA-5654741	0.0000001	0.0000003	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Signaling by FGFR1 Homo sapiens R-HSA-5654736	0.0000001	0.0000003	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	DAP12 signaling Homo sapiens R-HSA-2424491	0.0000001	0.0000003	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Signaling by EGFR Homo sapiens R-HSA-177929	0.0000001	0.0000004	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	DAP12 interactions Homo sapiens R-HSA-2172127	0.0000001	0.0000004	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Signaling by FGFR2 Homo sapiens R-HSA-5654738	0.0000001	0.0000004	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Signaling by FGFR Homo sapiens R-HSA-190236	0.0000001	0.0000004	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	NGF signalling via TRKA from the plasma membrane Homo sapiens R-HSA-187037	0.0000001	0.0000005	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Fc epsilon receptor (FCERI) signaling Homo sapiens R-HSA-2454202	0.0000002	0.0000007	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Cytokine Signaling in Immune system Homo sapiens R-HSA-1280215	0.0000003	0.0000009	RET;ERBB3;IL2RA;IL2RB;NRTN;PTPN6;CSF2RA;FGFR3
36	Immune System Homo sapiens R-HSA-168256	0.0000003	0.0000010	RET;ERBB3;IL2RA;IL2RB;NRTN;PTPN6;CSF2RA;LILRB4;FGFR3;RAP1GAP;LAIR1
36	GPVI-mediated activation cascade Homo sapiens R-HSA-114604	0.0000004	0.0000012	IL2RA;IL2RB;PTPN6;CSF2RA
36	Gastrin-CREB signalling pathway via PKC and MAPK Homo sapiens R-HSA-881907	0.0000004	0.0000012	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Signalling by NGF Homo sapiens R-HSA-166520	0.0000005	0.0000015	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Axon guidance Homo sapiens R-HSA-422475	0.0000012	0.0000036	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	Hemostasis Homo sapiens R-HSA-109582	0.0000020	0.0000056	GRB7;SLC7A7;IL2RA;IL2RB;PTPN6;SLC7A11;CSF2RA
36	Cell surface interactions at the vascular wall Homo sapiens R-HSA-202733	0.0000050	0.0000143	GRB7;SLC7A7;PTPN6;SLC7A11
36	Developmental Biology Homo sapiens R-HSA-1266738	0.0000199	0.0000545	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	G beta:gamma signalling through PI3Kgamma Homo sapiens R-HSA-392451	0.0000222	0.0000598	IL2RA;IL2RB;CSF2RA
36	Innate Immune System Homo sapiens R-HSA-168249	0.0000236	0.0000625	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3
36	G-protein beta:gamma signalling Homo sapiens R-HSA-397795	0.0000267	0.0000696	IL2RA;IL2RB;CSF2RA
36	Signaling by GPCR Homo sapiens R-HSA-372790	0.0000610	0.0001566	RET;ERBB3;IL2RA;IL2RB;NRTN;CSF2RA;FGFR3;WNT2
36	Adaptive Immune System Homo sapiens R-HSA-1280218	0.0001736	0.0004392	ERBB3;PTPN6;LILRB4;FGFR3;RAP1GAP;LAIR1
36	Platelet activation, signaling and aggregation Homo sapiens R-HSA-76002	0.0001832	0.0004567	IL2RA;IL2RB;PTPN6;CSF2RA
36	Signal Transduction Homo sapiens R-HSA-162582	0.0001975	0.0004850	RET;GRB7;ERBB3;IL2RA;IL2RB;NRTN;PTPN6;CSF2RA;FGFR3;WNT2
36	Disease Homo sapiens R-HSA-1643685	0.0012060	0.0028188	MUC1;ERBB3;CSPG5;CSF2RA;FGFR3
36	Signaling by the B Cell Receptor (BCR) Homo sapiens R-HSA-983705	0.0023269	0.0051813	ERBB3;PTPN6;FGFR3
36	GPCR downstream signaling Homo sapiens R-HSA-388396	0.1010516	0.1088750	IL2RA;IL2RB;CSF2RA
36	IL-2 Receptor Beta Chain in T cell Activation Homo sapiens h il2rbPathway	0.0000236	0.0001892	IL2RA;IL2RB;PTPN6
37	chromosome segregation (GO:0007059)	0.0000002	0.0000127	SKA3;NDC80;SKA1;ZWINT
37	mitotic nuclear division (GO:0007067)	0.0000093	0.0003341	SKA3;NDC80;SKA1;SPC24
37	nuclear division (GO:0000280)	0.0000218	0.0005222	SKA3;NDC80;SKA1;SPC24
37	organelle fission (GO:0048285)	0.0000306	0.0005502	SKA3;NDC80;SKA1;SPC24
37	mitotic cell cycle (GO:0000278)	0.0000714	0.0008528	NDC80;SKA1;SPC24;ZWINT
37	Resolution of Sister Chromatid Cohesion Homo sapiens R-HSA-2500257	0.0000003	0.0000027	NDC80;SKA1;SPC24;ZWINT
37	Mitotic Prometaphase Homo sapiens R-HSA-68877	0.0000004	0.0000027	NDC80;SKA1;SPC24;ZWINT
37	RHO GTPases Activate Formins Homo sapiens R-HSA-5663220	0.0000005	0.0000027	NDC80;SKA1;SPC24;ZWINT
37	Separation of Sister Chromatids Homo sapiens R-HSA-2467813	0.0000020	0.0000074	NDC80;SKA1;SPC24;ZWINT
37	Mitotic Anaphase Homo sapiens R-HSA-68882	0.0000025	0.0000074	NDC80;SKA1;SPC24;ZWINT
37	Mitotic Metaphase and Anaphase Homo sapiens R-HSA-2555396	0.0000026	0.0000074	NDC80;SKA1;SPC24;ZWINT
37	RHO GTPase Effectors Homo sapiens R-HSA-195258	0.0000118	0.0000286	NDC80;SKA1;SPC24;ZWINT
37	M Phase Homo sapiens R-HSA-68886	0.0000143	0.0000305	NDC80;SKA1;SPC24;ZWINT
37	Signaling by Rho GTPases Homo sapiens R-HSA-194315	0.0000491	0.0000928	NDC80;SKA1;SPC24;ZWINT
37	Cell Cycle, Mitotic Homo sapiens R-HSA-69278	0.0001201	0.0002041	NDC80;SKA1;SPC24;ZWINT
37	Cell Cycle Homo sapiens R-HSA-1640170	0.0002621	0.0004051	NDC80;SKA1;SPC24;ZWINT
37	Signal Transduction Homo sapiens R-HSA-162582	0.0504617	0.0659884	NDC80;SKA1;SPC24;ZWINT
39	epidermis development (GO:0008544)	0.0000000	0.0000008	KRT17;KRT16;KRT15;KRT14;KRT5;EVPL
39	intermediate filament cytoskeleton organization (GO:0045104)	0.0000001	0.0000064	KRT18;KRT17;KRT16;KRT14
39	intermediate filament-based process (GO:0045103)	0.0000001	0.0000064	KRT18;KRT17;KRT16;KRT14
39	keratinization (GO:0031424)	0.0000002	0.0000115	TGM1;KRT17;EVPL;PPL
39	epithelium development (GO:0060429)	0.0000003	0.0000140	KRT17;KRT16;KRT15;KRT14;KRT5;EVPL
39	tumor necrosis factor-mediated signaling pathway (GO:0033209)	0.0000048	0.0001587	KRT18;KRT8;TNFRSF4
39	epithelial cell differentiation (GO:0030855)	0.0000208	0.0005934	TGM1;KRT16;KRT14;PROM1;EVPL
39	cellular response to tumor necrosis factor (GO:0071356)	0.0001414	0.0023572	KRT18;KRT8;TNFRSF4
39	response to tumor necrosis factor (GO:0034612)	0.0002717	0.0038819	KRT18;KRT8;TNFRSF4
39	apoptotic signaling pathway (GO:0097190)	0.0060179	0.0415029	KRT18;KRT8;CD38
39	cytokine-mediated signaling pathway (GO:0019221)	0.0068107	0.0425667	KRT18;KRT8;TNFRSF4
39	response to inorganic substance (GO:0010035)	0.0084513	0.0469516	KRT16;KRT14;KRT8
39	cellular response to cytokine stimulus (GO:0071345)	0.0161960	0.0583697	KRT18;KRT8;TNFRSF4
39	Metabolic pathways Homo sapiens hsa01100	0.1677744	0.2034878	FOLH1;CD38;RIMKLA
41	‘de novo’ posttranslational protein folding (GO:0051084)	0.0000092	0.0010531	TUBA1C;TUBA1B;TUBB4B
41	‘de novo’ protein folding (GO:0006458)	0.0000123	0.0010531	TUBA1C;TUBA1B;TUBB4B
41	protein polymerization (GO:0051258)	0.0000206	0.0011731	TUBA1C;TUBA1B;TUBB4B
41	cellular protein complex assembly (GO:0043623)	0.0000547	0.0023397	TUBA1C;TUBA1B;TEKT2;TUBB4B
41	microtubule-based process (GO:0007017)	0.0004269	0.0145984	TUBA1C;TUBA1B;TUBB4B;DLGAP5
41	protein folding (GO:0006457)	0.0008072	0.0230053	TUBA1C;TUBA1B;TUBB4B
41	GTP catabolic process (GO:0006184)	0.0010620	0.0235187	TUBA1C;TUBA1B;TUBB4B
41	guanosine-containing compound catabolic process (GO:1901069)	0.0011003	0.0235187	TUBA1C;TUBA1B;TUBB4B
41	GTP metabolic process (GO:0046039)	0.0012620	0.0239786	TUBA1C;TUBA1B;TUBB4B
41	guanosine-containing compound metabolic process (GO:1901068)	0.0014229	0.0243310	TUBA1C;TUBA1B;TUBB4B
41	Pathogenic Escherichia coli infection Homo sapiens hsa05130	0.0000130	0.0001302	TUBA1C;TUBA1B;TUBB4B
41	Gap junction Homo sapiens hsa04540	0.0000535	0.0002676	TUBA1C;TUBA1B;TUBB4B
41	Phagosome Homo sapiens hsa04145	0.0002812	0.0009375	TUBA1C;TUBA1B;TUBB4B
41	Post-chaperonin tubulin folding pathway Homo sapiens R-HSA-389977	0.0000008	0.0000186	TUBA1C;TUBA1B;TUBB4B
41	Formation of tubulin folding intermediates by CCT/TriC Homo sapiens R-HSA-389960	0.0000012	0.0000186	TUBA1C;TUBA1B;TUBB4B
41	Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Homo sapiens R-HSA-389958	0.0000025	0.0000266	TUBA1C;TUBA1B;TUBB4B
41	Chaperonin-mediated protein folding Homo sapiens R-HSA-390466	0.0000673	0.0005167	TUBA1C;TUBA1B;TUBB4B
41	Protein folding Homo sapiens R-HSA-391251	0.0000807	0.0005167	TUBA1C;TUBA1B;TUBB4B
41	Cell Cycle, Mitotic Homo sapiens R-HSA-69278	0.0065432	0.0261729	TPX2;RRM2;TUBB4B
41	Cell Cycle Homo sapiens R-HSA-1640170	0.0114046	0.0331769	TPX2;RRM2;TUBB4B
41	Metabolism of proteins Homo sapiens R-HSA-392499	0.0598037	0.1062455	TUBA1C;TUBA1B;TUBB4B
44	interferon-gamma-mediated signaling pathway (GO:0060333)	0.0000001	0.0000019	OAS1;OAS2;OAS3
44	type I interferon signaling pathway (GO:0060337)	0.0000001	0.0000019	OAS1;OAS2;OAS3
44	cellular response to type I interferon (GO:0071357)	0.0000001	0.0000019	OAS1;OAS2;OAS3
44	response to type I interferon (GO:0034340)	0.0000001	0.0000019	OAS1;OAS2;OAS3
44	cellular response to interferon-gamma (GO:0071346)	0.0000003	0.0000037	OAS1;OAS2;OAS3
44	response to interferon-gamma (GO:0034341)	0.0000006	0.0000057	OAS1;OAS2;OAS3
44	defense response to virus (GO:0051607)	0.0000015	0.0000124	OAS1;OAS2;OAS3
44	response to virus (GO:0009615)	0.0000076	0.0000535	OAS1;OAS2;OAS3
44	defense response to other organism (GO:0098542)	0.0000173	0.0001075	OAS1;OAS2;OAS3
44	cytokine-mediated signaling pathway (GO:0019221)	0.0000196	0.0001096	OAS1;OAS2;OAS3
44	response to other organism (GO:0051707)	0.0000481	0.0002040	OAS1;OAS2;OAS3
44	cellular response to cytokine stimulus (GO:0071345)	0.0000510	0.0002040	OAS1;OAS2;OAS3
44	Hepatitis C Homo sapiens hsa05160	0.0000011	0.0000024	OAS1;OAS2;OAS3
44	Measles Homo sapiens hsa05162	0.0000012	0.0000024	OAS1;OAS2;OAS3
44	Influenza A Homo sapiens hsa05164	0.0000026	0.0000031	OAS1;OAS2;OAS3
44	Herpes simplex infection Homo sapiens hsa05168	0.0000031	0.0000031	OAS1;OAS2;OAS3
44	Interferon alpha/beta signaling Homo sapiens R-HSA-909733	0.0000001	0.0000007	OAS1;OAS2;OAS3
44	Interferon gamma signaling Homo sapiens R-HSA-877300	0.0000004	0.0000010	OAS1;OAS2;OAS3
44	Interferon Signaling Homo sapiens R-HSA-913531	0.0000037	0.0000061	OAS1;OAS2;OAS3
44	Cytokine Signaling in Immune system Homo sapiens R-HSA-1280215	0.0001159	0.0001448	OAS1;OAS2;OAS3
44	Immune System Homo sapiens R-HSA-168256	0.0017408	0.0017408	OAS1;OAS2;OAS3
52	striated muscle tissue development (GO:0014706)	0.0000003	0.0000244	SIX4;EYA2;SIX1
52	muscle tissue development (GO:0060537)	0.0000004	0.0000244	SIX4;EYA2;SIX1
52	embryonic morphogenesis (GO:0048598)	0.0000320	0.0001808	SIX4;EYA4;SIX1
56	translation (GO:0006412)	0.0000000	0.0000000	RPL39L;MRPS12;MRPL14;MRPL47;MRPL15;MRPL13
56	Ribosome Homo sapiens hsa03010	0.0000003	0.0000021	MRPS12;MRPL14;MRPL15;MRPL13
56	Mitochondrial translation initiation Homo sapiens R-HSA-5368286	0.0000000	0.0000000	MRPS12;MRPL14;MRPL47;MRPL15;MRPL13
56	Mitochondrial translation termination Homo sapiens R-HSA-5419276	0.0000000	0.0000000	MRPS12;MRPL14;MRPL47;MRPL15;MRPL13
56	Mitochondrial translation elongation Homo sapiens R-HSA-5389840	0.0000000	0.0000000	MRPS12;MRPL14;MRPL47;MRPL15;MRPL13
56	Mitochondrial translation Homo sapiens R-HSA-5368287	0.0000000	0.0000000	MRPS12;MRPL14;MRPL47;MRPL15;MRPL13
56	Organelle biogenesis and maintenance Homo sapiens R-HSA-1852241	0.0000001	0.0000003	MRPS12;MRPL14;MRPL47;MRPL15;MRPL13
61	Wnt signaling pathway (GO:0016055)	0.0000000	0.0000000	RNF43;KREMEN2;RSPO1;LGR6;RSPO4
61	regulation of Wnt signaling pathway (GO:0030111)	0.0000002	0.0000025	RNF43;RSPO1;LGR6;LGR5
61	positive regulation of canonical Wnt signaling pathway (GO:0090263)	0.0000005	0.0000044	RSPO1;LGR6;LGR5
61	positive regulation of Wnt signaling pathway (GO:0030177)	0.0000015	0.0000103	RSPO1;LGR6;LGR5
61	regulation of canonical Wnt signaling pathway (GO:0060828)	0.0000085	0.0000457	RSPO1;LGR6;LGR5
61	Regulation of FZD by ubiquitination Homo sapiens R-HSA-4641263	0.0000000	0.0000000	RNF43;RSPO1;LGR6;LGR5;RSPO4
61	TCF dependent signaling in response to WNT Homo sapiens R-HSA-201681	0.0000000	0.0000000	RNF43;KREMEN2;RSPO1;LGR6;LGR5;RSPO4
61	Signaling by Wnt Homo sapiens R-HSA-195721	0.0000000	0.0000000	RNF43;KREMEN2;RSPO1;LGR6;LGR5;RSPO4
61	Signal Transduction Homo sapiens R-HSA-162582	0.0000035	0.0000087	RNF43;KREMEN2;RSPO1;LGR6;LGR5;RSPO4
70	nucleobase metabolic process (GO:0009112)	0.0000000	0.0000045	PNP;XDH;TYMP
70	Metabolic pathways Homo sapiens hsa01100	0.0002372	0.0004744	PNP;XDH;TYMP
70	Metabolism of nucleotides Homo sapiens R-HSA-15869	0.0000001	0.0000006	PNP;XDH;TYMP
70	Metabolism Homo sapiens R-HSA-1430728	0.0008670	0.0017340	PNP;XDH;TYMP

In this table the genes are ordered by their combined rank score which is a normalised score with the following contributions.

• Betweeness: 10%
• Citation score: 20%
• Degree centrality: 30%
• Druggability: 40%

Ordered by Combined Rank Score

external_gene_name	uniprot_gn_id	cluster	betweenness	degree_centrality	pocket	druggability	num_drug_pockets	struct_score	logFC	regulation	citation_score	combined_score
H2BC4	P62807	2	38282	12	0.291	0.965	1	87.82973	2.638893	up_reg	0	0.6168408
H2BC12	O60814	2	24896	11	0.241	0.937	1	88.05779	3.203629	up_reg	2	0.5548266
H2BC9	Q93079	2	24695	11	0.364	0.940	2	88.14311	4.450921	up_reg	3	0.5511852
PLK1	P53350	2	53880	14	0.175	0.953	2	85.16989	3.894749	up_reg	2971	0.5370856
LYN	P07948	2	49848	19	0.072	0.759	1	83.72670	2.498330	up_reg	3594	0.5347776
KIF9	Q9HAQ2	2	7104	13	0.202	0.885	1	75.21325	2.195679	up_reg	31	0.5074970
RAC3	P60763	2	18877	11	0.341	0.937	1	93.83371	2.514936	up_reg	299	0.4738508
H2BC11	P06899	2	72	9	0.250	0.870	2	85.69804	3.968938	up_reg	1	0.4703589
CCNB1	P14635	2	76783	14	0.078	0.699	1	77.77241	3.784353	up_reg	2285	0.4680967
KIF20A	O95235	2	24557	13	0.333	0.814	3	67.30456	5.657319	up_reg	301	0.4649268
CD3E	P07766	2	14667	11	0.191	0.884	1	73.51280	2.881956	up_reg	540	0.4380146
LCK	P06239	2	54987	19	0.188	0.471	1	84.33331	2.329222	up_reg	3794	0.4250908
KIF11	P52732	2	1046	9	0.141	0.991	1	74.76864	4.407716	up_reg	820	0.4239201
GRIK3	Q13003	2	17866	8	0.152	0.878	1	82.38048	3.473939	up_reg	66	0.4229241
SYK	P43405	2	13379	10	0.203	0.979	2	84.33036	4.407191	up_reg	5393	0.4210437
KLC3	Q6P597	11	3	3	0.212	0.991	1	76.01520	4.822387	up_reg	19	0.3819201
UBE2S	Q16763	2	77901	9	0.168	0.552	1	81.85029	2.769728	up_reg	116	0.3747951
ATP5MC1	P05496	2	3791	3	0.401	0.898	1	72.69576	2.063501	up_reg	4	0.3715486
TOP2A	P11388	2	22036	7	0.045	0.897	1	76.40832	5.212828	up_reg	1327	0.3713590
KIF15	Q9NS87	2	2175	7	0.241	0.869	1	72.02130	3.950703	up_reg	155	0.3696949
APOA1	P02647	2	9356	8	0.278	0.929	3	73.61168	3.065972	up_reg	3491	0.3696582
RAC2	P15153	2	1171	7	0.227	0.939	1	93.54571	2.156389	up_reg	917	0.3681594
CENPU	Q71F23	2	0	3	0.002	0.994	1	65.51860	3.558826	up_reg	59	0.3655807
PLPP4	Q5VZY2	45	0	1	0.383	0.993	2	92.00338	5.658002	up_reg	11	0.3575367
TGFA	P01135	2	3905	5	0.202	0.961	1	66.88685	4.466767	up_reg	481	0.3573023
NAXE	Q8NCW5	2	1521	3	0.423	0.962	1	86.87614	2.208627	up_reg	51	0.3569523
CENPE	Q02224	2	1501	4	0.135	0.997	5	72.55249	2.847355	up_reg	436	0.3536167
PKP3	Q9Y446	2	31976	3	0.070	0.881	1	69.28451	7.141531	up_reg	91	0.3532397
PPP4C	P60510	2	1521	3	0.387	0.933	1	94.87746	2.136177	up_reg	32	0.3526107
BNIPL	Q7Z465	2	0	1	0.190	0.996	1	68.65183	3.984513	up_reg	17	0.3522648
LAMA5	O15230	2	3467	4	0.086	0.946	2	79.24314	2.244719	up_reg	154	0.3522009
LRRC43	Q8N309	2	0	1	0.240	0.879	1	74.70035	2.069984	up_reg	0	0.3516000
CACNA1F	O60840	2	1139	3	0.170	0.999	5	67.32468	3.652392	up_reg	184	0.3510211
RIMKLA	Q8IXN7	2	0	1	0.297	0.938	1	81.13650	3.884952	up_reg	4	0.3495106
TPM3	P06753	2	8572	8	0.348	0.799	1	91.78888	2.201758	up_reg	485	0.3481620
FAAH2	Q6GMR7	23	0	1	0.082	0.995	1	94.18245	3.735525	up_reg	24	0.3466213
KCNK12	Q9HB15	36	0	1	0.139	0.994	1	73.78490	2.598125	up_reg	25	0.3455953
NDUFB9	Q9Y6M9	2	4536	2	-0.051	0.948	1	96.13232	2.289772	up_reg	33	0.3452091
MYO3B	Q8WXR4	2	0	2	0.144	0.942	1	75.66990	6.420588	up_reg	22	0.3434189
BAIAP2L1	Q9UHR4	2	3579	4	0.324	0.876	2	74.93578	4.062937	up_reg	46	0.3433866
LAMA5	O15230	2	3467	4	0.241	0.919	3	79.99285	2.244719	up_reg	154	0.3414009
ASPM	Q8IZT6	2	8922	4	0.434	0.949	4	62.64048	4.312243	up_reg	510	0.3411291
LAMA5	O15230	2	3467	4	0.244	0.918	2	82.41367	2.244719	up_reg	154	0.3410009
PPP1CA	P62136	2	17077	14	0.206	0.440	1	91.55269	2.763584	up_reg	98	0.3405131
FAM166B	A8MTA8	2	0	6	0.110	0.707	1	69.27333	3.014622	up_reg	4	0.3404440
ATP5MF	P56134	2	0	1	0.423	0.892	3	74.16835	2.318005	up_reg	2	0.3392643
BRCA2	P51587	2	32217	9	0.083	0.796	1	65.83808	2.245119	up_reg	14293	0.3389992
CENPE	Q02224	2	1501	4	0.126	0.960	2	70.76444	2.847355	up_reg	436	0.3388167
DNAH3	Q8TD57	24	0	1	0.164	0.960	4	85.66639	3.642484	up_reg	16	0.3387771
H4C9	P62805	2	13910	7	0.336	0.581	1	90.43752	4.248213	up_reg	1	0.3385983
TJP3	O95049	2	0	4	0.067	0.880	2	66.58409	6.724088	up_reg	60	0.3363835
AGR2	O95994	2	5272	5	0.263	0.901	1	87.41946	5.133482	up_reg	449	0.3360952
SLC35F2	Q8IXU6	2	0	1	-0.002	0.970	2	82.73241	2.149731	up_reg	26	0.3353929
TEAD4	Q15561	2	1521	3	0.243	0.986	2	76.58312	2.660133	up_reg	381	0.3347219
SULT1C2	O00338	53	0	1	0.298	0.998	1	95.75467	4.617490	up_reg	56	0.3346661
CENPE	Q02224	2	1501	4	0.416	0.949	1	70.84160	2.847355	up_reg	436	0.3344167
BRCA2	P51587	2	32217	9	0.066	0.783	2	62.08251	2.245119	up_reg	14293	0.3337992
HLA-DOA	P06340	2	7	4	0.429	0.874	1	90.25303	3.324934	up_reg	61	0.3337326
HLA-DPA1	P20036	2	40869	5	0.282	0.776	1	90.64308	3.525234	up_reg	363	0.3336560
MAPK15	Q8TD08	20	0	1	0.055	1.000	1	69.39014	4.731041	up_reg	63	0.3336172
ASPM	Q8IZT6	2	8922	4	0.335	0.927	1	64.38947	4.312243	up_reg	510	0.3323291
TNFAIP8L2	Q6P589	2	761	2	0.017	0.981	1	90.74994	2.015314	up_reg	130	0.3321947
FBN2	P35556	12	7	3	0.107	0.975	1	75.78393	2.521524	up_reg	313	0.3315720
TNFRSF12A	Q9NP84	2	1609	4	0.111	0.942	1	73.27291	3.640033	up_reg	446	0.3313896
DNAH3	Q8TD57	24	0	1	0.099	0.941	1	85.25115	3.642484	up_reg	16	0.3311771
NINJ2	Q9NZG7	2	0	1	0.185	0.987	3	67.54372	3.668185	up_reg	59	0.3294473
KRT86	O43790	2	13	5	0.408	0.788	4	75.55742	5.650357	up_reg	27	0.3286952
BUB1B	O60566	2	3360	6	0.211	0.846	2	64.72058	4.320179	up_reg	471	0.3276272
SGPP2	Q8IWX5	45	0	1	0.102	0.966	1	84.21180	5.853240	up_reg	40	0.3271251
VANGL1	Q8TAA9	2	4805	6	0.038	0.796	2	75.85692	2.706602	up_reg	163	0.3262938
MRPL47	Q9HD33	2	1164	3	0.233	0.830	1	84.37084	2.125313	up_reg	12	0.3258369
TUBB4B	P68371	2	4864	8	0.258	0.659	2	92.02804	2.059976	up_reg	44	0.3255420
CLDN10	P78369	2	8628	9	0.400	0.636	1	79.69633	6.283497	up_reg	99	0.3249343
TSPAN33	Q86UF1	2	0	1	0.034	0.951	2	89.66649	2.598895	up_reg	32	0.3245898
ZNF492	Q9P255	56	0	1	0.218	0.888	1	73.55861	2.697025	up_reg	6	0.3241400
IL4I1	Q96RQ9	10	0	1	0.511	1.000	1	86.82116	7.731687	up_reg	124	0.3229319
CNIH2	Q6PI25	2	19080	5	0.314	0.723	2	87.25387	2.690596	up_reg	37	0.3214827
SULT2B1	O00204	53	0	1	0.599	0.996	1	87.72190	4.651085	up_reg	124	0.3213319
MARVELD3	Q96A59	2	0	3	0.108	0.860	1	65.32157	3.677035	up_reg	36	0.3196970
CENPA	P49450	2	17610	6	0.140	0.815	2	82.07836	6.059723	up_reg	1089	0.3195521
LGR6	Q9HBX8	37	0	2	0.408	0.967	2	78.17419	3.761788	up_reg	191	0.3195481
RTN2	O75298	49	0	1	0.162	0.944	2	51.12613	2.365362	up_reg	37	0.3195380
FBN3	Q75N90	12	0	1	0.195	0.958	2	75.30388	5.054065	up_reg	53	0.3195291
SLC16A3	O15427	2	1520	2	0.025	0.963	1	83.58743	2.015156	up_reg	195	0.3195053
MPZL2	O60487	40	0	1	0.433	0.937	2	89.47771	3.309876	up_reg	35	0.3176010
H4C8	P62805	2	5828	7	0.336	0.581	1	90.43752	2.770586	up_reg	3	0.3175049
LY86	O95711	15	0	1	0.075	0.983	1	87.70983	3.088945	up_reg	119	0.3167835
CFAP45	Q9UL16	2	1552	5	0.131	0.728	3	74.80989	2.226990	up_reg	15	0.3155375
ATP10B	O94823	9	0	1	0.117	0.904	2	71.43291	5.180540	up_reg	18	0.3146018
CENPF	P49454	2	10672	3	0.122	0.906	1	71.41875	4.302935	up_reg	385	0.3139119
CYP4F3	Q08477	22	0	1	0.156	0.961	2	91.82752	4.018495	up_reg	84	0.3134878
RIBC2	Q9H4K1	2	2064	7	0.365	0.625	1	86.74874	3.939408	up_reg	11	0.3128981
TSPAN15	O95858	2	2277	2	0.296	0.875	2	87.94298	3.591096	up_reg	34	0.3127430
USP43	Q70EL4	2	470	2	0.025	0.846	2	61.36801	3.739775	up_reg	14	0.3124249
CACNA1B	Q00975	2	6	2	0.130	0.971	2	60.38413	4.783153	up_reg	334	0.3122707
FBN2	P35556	12	7	3	0.286	0.926	1	75.56676	2.521524	up_reg	313	0.3119720
LPAR5	Q9H1C0	2	0	1	0.250	0.967	1	83.69589	3.173233	up_reg	108	0.3119181
UNC93B1	Q9H1C4	54	0	1	0.082	0.986	1	80.17879	3.392612	up_reg	175	0.3118703
ALDH3A1	P30838	5	0	2	0.345	0.966	1	97.89977	3.119278	up_reg	316	0.3111448
MCM4	P33991	2	9512	9	0.217	0.658	3	73.74330	2.743419	up_reg	448	0.3108592
LAPTM5	Q13571	38	0	1	0.239	0.964	2	69.27503	2.290592	up_reg	113	0.3100023
DNAH3	Q8TD57	24	0	1	0.172	0.885	2	86.96104	3.642484	up_reg	16	0.3087771
AP1S3	Q96PC3	2	11076	13	0.308	0.385	0	93.25617	3.118487	up_reg	40	0.3084703
HCST	Q9UBK5	2	1076	3	0.330	0.904	2	67.31898	2.736939	up_reg	246	0.3083295
RYR1	P21817	2	1899	4	0.226	0.997	3	75.55434	3.086482	up_reg	7993	0.3077177
TUBA1C	Q9BQE3	2	861	2	0.219	0.883	1	91.65244	3.360826	up_reg	52	0.3075626
LAMA5	O15230	2	3467	4	0.204	0.833	5	78.94328	2.244719	up_reg	154	0.3070009
STC2	O76061	2	0	2	0.270	0.960	2	73.29585	3.187642	up_reg	353	0.3069827
CENPE	Q02224	2	1501	4	0.191	0.880	2	74.15316	2.847355	up_reg	436	0.3068167
CD9	P21926	2	1521	3	0.063	0.994	1	88.11915	3.619361	up_reg	2704	0.3066779
DNAH3	Q8TD57	24	0	1	0.312	0.878	4	88.06644	3.642484	up_reg	16	0.3059771
SDC4	P31431	2	4689	3	0.270	0.917	2	63.14462	2.128542	up_reg	556	0.3050335
KLHL14	Q9P2G3	6	0	1	0.483	0.887	1	88.14009	5.754363	up_reg	22	0.3047522
EPPK1	P58107	2	0	1	0.247	0.908	1	77.46931	6.941326	up_reg	38	0.3047234
RYR1	P21817	2	1899	4	0.145	0.989	2	76.51895	3.086482	up_reg	7993	0.3045177
CENPL	Q8N0S6	2	4202	4	0.229	0.746	2	83.65047	2.321809	up_reg	22	0.3035668
NRCAM	Q92823	2	1726	4	0.090	0.859	2	78.95628	2.470745	up_reg	323	0.3034715
ADGRG1	Q9Y653	2	0	1	0.294	0.960	2	78.01376	4.084734	up_reg	168	0.3021181
SVOPL	Q8N434	49	0	1	0.061	0.862	1	84.05384	3.101728	up_reg	14	0.3015749
PERP	Q96FX8	2	31898	6	0.129	0.705	1	82.35155	3.211249	up_reg	673	0.3009562
DNAH3	Q8TD57	24	0	1	0.156	0.864	1	85.29108	3.642484	up_reg	16	0.3003771
FBN3	Q75N90	12	0	1	0.138	0.909	1	70.40952	5.054065	up_reg	53	0.2999291
GPR37	O15354	2	0	1	0.097	0.945	5	61.81102	4.508915	up_reg	144	0.2985629
CTSC	P53634	2	0	3	0.338	0.892	2	90.37857	2.162863	up_reg	316	0.2982115
TTK	P33981	2	3035	3	0.087	0.956	1	63.95435	5.915254	up_reg	2047	0.2977979
CHST6	Q9GZX3	18	0	1	0.409	0.920	1	90.80083	5.468416	up_reg	84	0.2970878
ANLN	Q9NQW6	2	10469	5	0.121	0.760	1	59.87419	3.455958	up_reg	227	0.2969970
ACTR3C	Q9C0K3	2	0	1	0.040	0.786	1	88.11260	2.000050	up_reg	2	0.2968643
AQP9	O43315	2	0	1	0.470	0.998	1	91.06600	3.553111	up_reg	637	0.2961140
RSAD2	Q8WXG1	2	380	2	0.193	0.935	1	87.95684	2.536852	up_reg	393	0.2957456
ARFGEF3	Q5TH69	2	0	1	0.051	0.852	3	65.48151	3.121775	up_reg	16	0.2955771
ASPM	Q8IZT6	2	8922	4	0.121	0.835	1	67.46659	4.312243	up_reg	510	0.2955291
LAMA5	O15230	2	3467	4	0.150	0.804	1	81.67851	2.244719	up_reg	154	0.2954009
B3GNT3	Q9Y2A9	2	3789	3	0.149	0.793	1	88.42372	7.460360	up_reg	42	0.2952003
NR2F6	P10588	2	0	1	0.399	0.917	1	79.75002	3.297460	up_reg	89	0.2949754
MELK	Q14680	2	0	1	0.159	0.993	1	70.64372	5.528457	up_reg	659	0.2935729
FBN2	P35556	12	7	3	0.139	0.880	1	75.06254	2.521524	up_reg	313	0.2935720
ERBB4	Q15303	2	3810	3	0.069	0.951	1	73.09162	5.365254	up_reg	2501	0.2935637
MUC5B	Q9HC84	2	1020	3	0.112	0.930	1	82.35068	5.737039	up_reg	1207	0.2933234
TDO2	P48775	34	0	1	0.175	0.947	1	90.52437	5.860687	up_reg	223	0.2924210
AURKB	Q96GD4	2	7020	6	0.060	0.789	2	79.85404	5.582702	up_reg	1367	0.2923840
DIAPH3	Q9NSV4	2	322	2	0.164	0.866	2	71.81813	4.609425	up_reg	86	0.2921828
AIFM1	O95831	2	39	2	0.136	0.947	1	85.79458	2.212459	up_reg	647	0.2921808
CDC6	Q99741	2	761	3	0.244	0.922	2	69.83948	3.142206	up_reg	1059	0.2918882
BRCA2	P51587	2	32217	9	0.092	0.678	3	62.85491	2.245119	up_reg	14293	0.2917992
DNAH5	Q8TE73	24	0	1	0.234	0.936	1	81.69210	3.828651	up_reg	183	0.2911608
XDH	P47989	46	0	1	0.138	0.993	3	96.09594	7.452060	up_reg	800	0.2904823
KREMEN2	Q8NCW0	37	0	1	0.459	0.870	1	76.82793	7.640887	up_reg	36	0.2903636
CCNO	P22674	2	761	3	0.405	0.838	2	79.73102	2.663074	up_reg	142	0.2902623
CYP2J2	P51589	22	0	1	0.080	0.987	1	93.78906	4.606358	up_reg	707	0.2900523
CX3CR1	P49238	2	1960	6	0.114	0.832	2	80.21817	4.725471	up_reg	3143	0.2900221
DNAH5	Q8TE73	24	0	1	0.124	0.932	3	85.07114	3.828651	up_reg	183	0.2895608
ASPM	Q8IZT6	2	8922	4	0.163	0.820	2	68.83865	4.312243	up_reg	510	0.2895291
CYBA	P13498	2	0	2	0.480	0.957	1	77.02989	3.871486	up_reg	1043	0.2885199
ANPEP	P15144	2	761	2	0.232	0.886	1	93.75126	3.535249	up_reg	188	0.2883439
TIMELESS	Q9UNS1	2	2280	6	0.482	0.784	2	75.06448	2.414253	up_reg	1146	0.2873142
IFI27	P40305	2	0	1	0.066	0.942	1	52.14211	4.811702	up_reg	273	0.2872050
LRRC46	Q96FV0	2	0	1	0.095	0.800	1	64.78600	2.513569	up_reg	7	0.2868086
LAMA5	O15230	2	3467	4	0.102	0.782	2	78.13025	2.244719	up_reg	154	0.2866009
COX5A	P20674	2	14138	6	0.376	0.660	1	88.10962	2.578447	up_reg	134	0.2865819
CDC45	O75419	2	884	2	0.323	0.926	1	92.88743	4.831525	up_reg	594	0.2861914
ATP6V0E2	Q8NHE4	2	1521	3	0.416	0.712	1	94.37485	2.427263	up_reg	8	0.2849494
RMI2	Q96E14	2	2582	7	0.286	0.624	1	89.81185	2.702399	up_reg	75	0.2836784
MSR1	P21757	2	2506	6	0.363	0.749	1	71.98684	2.514585	up_reg	611	0.2836213
DNAH5	Q8TE73	24	0	1	2.178	0.916	3	87.27259	3.828651	up_reg	183	0.2831608
NOX4	Q9NPH5	2	322	2	0.046	0.993	3	86.75705	2.565399	up_reg	3755	0.2828838
FCER1G	P30273	2	1521	4	0.480	0.783	1	72.33766	3.253477	up_reg	173	0.2827403
ASPM	Q8IZT6	2	8922	4	0.163	0.803	2	63.49329	4.312243	up_reg	510	0.2827291
GRIN2D	O15399	2	0	2	0.143	0.846	3	64.00209	3.116091	up_reg	93	0.2825480
H3C8	P68431	2	11	3	0.351	0.623	1	87.28692	7.878421	up_reg	0	0.2825470
H3C10	P68431	2	0	3	0.351	0.623	1	87.28692	2.688200	up_reg	0	0.2825333
CENPF	P49454	2	10672	3	0.372	0.826	1	72.00170	4.302935	up_reg	385	0.2819119
PLEKHH1	Q9ULM0	2	0	1	0.175	0.767	2	70.18185	2.350357	up_reg	4	0.2811106
KRT8	P05787	2	4632	6	0.432	0.721	1	76.32674	6.489903	up_reg	425	0.2808425
ITGB8	P26012	2	0	1	0.085	0.896	1	76.46707	2.820420	up_reg	131	0.2804622
TMC6	Q7Z403	2	761	2	0.125	0.830	6	72.55287	2.977559	up_reg	76	0.2802766
UPK3B	Q9BT76	2	0	1	0.394	0.821	1	52.89733	4.391774	up_reg	21	0.2790617
KIF14	Q15058	2	5312	10	0.127	0.506	1	66.04636	4.471441	up_reg	163	0.2775896
DNAH3	Q8TD57	24	0	1	0.199	0.807	4	87.74512	3.642484	up_reg	16	0.2775771
P2RY2	P41231	43	0	1	0.120	0.939	1	79.19662	4.039141	up_reg	470	0.2773580
IL32	P24001	2	0	1	0.099	0.950	2	71.19002	3.002851	up_reg	626	0.2771916
CCND1	P24385	2	30015	9	0.313	0.616	2	88.55158	3.545879	up_reg	6387	0.2771224
SPTBN2	O15020	2	4273	4	0.242	0.736	3	76.77521	4.481006	up_reg	98	0.2763568
HAS2	Q92819	2	0	1	0.103	0.970	1	90.70737	2.317929	up_reg	1108	0.2760892
LRP2	P98164	2	761	2	0.255	0.887	1	81.80994	4.927297	up_reg	452	0.2747911
IDO1	P14902	34	0	1	0.277	0.991	1	93.39839	5.743478	up_reg	2039	0.2747606
ESPL1	Q14674	2	0	1	0.619	0.885	1	75.77835	4.967101	up_reg	146	0.2743442
CYBB	P04839	2	1700	2	0.295	0.952	3	90.39584	2.576950	up_reg	2670	0.2736353
KIF18B	Q86Y91	2	764	11	0.200	0.437	1	62.74387	5.536292	up_reg	74	0.2735004
CXADR	P78310	2	0	1	0.405	0.860	1	79.48562	5.200874	up_reg	83	0.2732767
CDCP1	Q9H5V8	2	0	1	0.276	0.901	1	78.35387	5.466835	up_reg	234	0.2732558
MGST1	P10620	39	0	1	0.541	0.900	1	79.02661	3.365294	up_reg	238	0.2725864
DNAH5	Q8TE73	24	0	1	0.237	0.889	1	80.09468	3.828651	up_reg	183	0.2723608
NRAS	P01111	2	8745	6	0.256	0.798	1	92.29668	2.115169	up_reg	7121	0.2717905
CDK1	P06493	2	17675	13	0.514	0.471	1	89.31551	4.500461	up_reg	5957	0.2715876
TRPV6	Q9H1D0	2	0	1	0.341	0.941	3	80.74593	3.389083	up_reg	747	0.2707750
PBK	Q96KB5	2	0	2	0.152	0.901	1	84.90700	5.819542	up_reg	782	0.2707118
IFIT1	P09914	2	0	1	0.057	0.930	1	94.17439	2.860614	up_reg	577	0.2704904
GJB2	P29033	2	1520	2	0.236	0.943	2	86.38640	5.456850	up_reg	2564	0.2704582
NDUFB11	Q9NX14	2	0	1	0.410	0.818	1	78.63169	2.037892	up_reg	35	0.2700010
ASPM	Q8IZT6	2	8922	4	0.107	0.769	2	62.01828	4.312243	up_reg	510	0.2691291
RYR1	P21817	2	1899	4	0.185	0.900	2	84.43495	3.086482	up_reg	7993	0.2689177
DNAH5	Q8TE73	24	0	1	0.179	0.880	2	80.01153	3.828651	up_reg	183	0.2687608
LRP2	P98164	2	761	2	0.153	0.871	1	76.00288	4.927297	up_reg	452	0.2683911
CACNA1A	O00555	2	4536	3	0.201	0.851	2	57.97536	2.232175	up_reg	1045	0.2683851
STAT1	P42224	2	28968	10	0.247	0.581	2	88.26074	2.024616	up_reg	12059	0.2683465
CENPF	P49454	2	10672	3	0.307	0.792	6	71.55613	4.302935	up_reg	385	0.2683119
PIPOX	Q9P0Z9	2	453	2	0.845	0.789	3	94.41585	3.104421	up_reg	59	0.2674762
PYCR1	P32322	47	0	1	0.336	0.869	2	90.06781	2.897004	up_reg	158	0.2666917
KCNJ12	Q14500	2	0	1	0.160	0.823	2	81.21053	2.050148	up_reg	50	0.2664414
HMMR	O75330	2	0	1	0.192	0.886	2	76.10490	5.098101	up_reg	249	0.2662681
FSBP	O95073	2	0	1	0.297	0.828	1	70.03120	2.914093	up_reg	58	0.2661156
CXXC5	Q7LFL8	2	0	1	0.110	0.849	1	60.75966	4.423334	up_reg	99	0.2660937
PTGS1	P23219	2	0	2	0.142	0.943	1	94.11557	5.423793	up_reg	3039	0.2658601
LGALS9	O00182	2	0	1	0.247	0.914	3	85.12848	2.655331	up_reg	533	0.2653542
NQO1	P15559	2	761	2	0.254	0.963	1	98.32853	2.893693	up_reg	5539	0.2652253
ADGRE2	Q9UHX3	2	0	1	0.306	0.819	2	79.23141	2.147655	up_reg	49	0.2651575
IL27RA	Q6UWB1	2	761	2	0.336	0.833	1	79.02110	2.953478	up_reg	214	0.2650866
ASS1	P00966	2	0	1	0.103	0.902	1	95.63537	3.299729	up_reg	402	0.2650468
SECTM1	Q8WVN6	2	0	1	0.407	0.792	1	75.41749	2.268843	up_reg	26	0.2641929
ASPM	Q8IZT6	2	8922	4	0.305	0.756	1	71.82009	4.312243	up_reg	510	0.2639291
ORC1	Q13415	2	2071	4	0.154	0.765	1	67.97461	2.787799	up_reg	375	0.2639238
BRCA2	P51587	2	32217	9	0.270	0.607	2	50.76375	2.245119	up_reg	14293	0.2633992
LAPTM4B	Q86VI4	38	0	1	0.211	0.865	1	61.67725	3.214999	up_reg	179	0.2631116
DSP	P15924	2	2832	2	0.154	0.950	1	78.56539	4.716943	up_reg	5445	0.2628685
TNFSF10	P50591	2	761	2	0.184	0.940	1	82.39667	2.187216	up_reg	3737	0.2623053
KPNA2	P52292	2	2308	5	0.024	0.711	1	86.10732	3.953899	up_reg	312	0.2622117
GJB1	P08034	2	0	1	0.333	0.890	1	80.05050	7.474133	up_reg	358	0.2620922
FAM3B	P58499	30	0	1	0.319	0.821	2	93.09627	6.055449	up_reg	64	0.2617697
RORC	P51449	2	0	1	0.252	0.940	1	75.84376	4.448796	up_reg	1288	0.2616884
FBN3	Q75N90	12	0	1	0.154	0.808	1	75.06968	5.054065	up_reg	53	0.2595291
CENPF	P49454	2	10672	3	0.416	0.769	3	73.15360	4.302935	up_reg	385	0.2591119
MRPS12	O15235	2	1743	3	0.312	0.667	1	87.35241	2.446360	up_reg	14	0.2590713
RASAL1	O95294	2	0	1	0.120	0.818	3	88.58747	6.257054	up_reg	78	0.2574562
AP1M2	Q9Y6Q5	2	7501	13	0.188	0.268	0	93.09129	8.570288	up_reg	40	0.2572337
ALDH3B2	P48448	5	0	2	0.218	0.732	2	94.98486	8.969782	up_reg	26	0.2568595
SLC7A7	Q9UM01	2	0	1	0.011	0.853	1	83.51919	2.184124	up_reg	198	0.2567099
BIK	Q13323	2	761	2	0.409	0.883	2	62.54290	6.029953	up_reg	1275	0.2566612
ASB9	Q96DX5	8	1	2	0.225	0.738	1	92.22385	2.355072	up_reg	31	0.2565489
TUBA1B	P68363	2	117	2	0.192	0.760	2	92.25708	2.287882	up_reg	57	0.2560003
CLDN6	P56747	2	4049	7	0.114	0.566	1	80.73011	12.449902	up_reg	114	0.2556876
GJB3	O75712	2	761	2	0.462	0.826	4	79.18052	6.360123	up_reg	328	0.2554962
SKA3	Q8IX90	2	4414	4	0.354	0.683	1	64.75869	5.662079	up_reg	97	0.2554939
NCAPD2	Q15021	2	0	3	0.115	0.697	1	79.98735	2.560562	up_reg	36	0.2544970
HTR3A	P46098	2	0	1	0.422	0.858	2	83.46451	10.598163	up_reg	265	0.2540779
LRP2	P98164	2	761	2	0.105	0.834	5	80.79603	4.927297	up_reg	452	0.2535911
RYR1	P21817	2	1899	4	0.108	0.861	2	81.22953	3.086482	up_reg	7993	0.2533177
FZD2	Q14332	2	1521	3	0.544	0.766	4	84.43777	2.649653	up_reg	254	0.2531729
IL2RA	P01589	2	0	1	0.000	0.936	1	72.50829	2.966958	up_reg	1993	0.2531247
BCL2L1	Q07817	2	2177	5	0.269	0.820	1	73.63605	2.256294	up_reg	8522	0.2529066
HDAC9	Q9UKV0	2	8	6	0.104	0.668	2	64.41926	2.313913	up_reg	455	0.2528179
DAPP1	Q9UN19	2	0	1	0.046	0.794	1	79.27173	3.771736	up_reg	58	0.2525156
SCARA3	Q6AZY7	50	0	1	0.222	0.790	4	71.06544	2.625480	up_reg	53	0.2523291
PTX3	P26022	2	135	2	0.266	0.891	2	79.75132	2.728436	up_reg	2010	0.2518234
CENPE	Q02224	2	1501	4	0.304	0.741	2	72.44087	2.847355	up_reg	436	0.2512167
PLPP2	O43688	45	1	2	0.205	0.694	1	85.85271	3.843634	up_reg	14	0.2510428
CACNG4	Q9UBN1	2	5285	2	0.125	0.712	1	65.72441	6.967106	up_reg	36	0.2503889
GNGT1	P63211	2	9443	6	0.318	0.524	1	88.83912	3.959000	up_reg	29	0.2503631
DNAH5	Q8TE73	24	0	1	0.335	0.834	3	83.36204	3.828651	up_reg	183	0.2503608
RTKN	Q9BST9	2	0	1	0.115	0.793	1	72.73822	2.656687	up_reg	69	0.2493868
IRF6	O14896	2	90	2	0.289	0.829	1	74.17857	3.540215	up_reg	507	0.2489293
LRP2	P98164	2	761	2	0.226	0.822	1	82.61401	4.927297	up_reg	452	0.2487911
PKMYT1	Q99640	2	16270	3	0.142	0.674	1	75.59028	5.618007	up_reg	107	0.2483895
NKG7	Q16617	2	0	1	0.270	0.797	1	86.50265	3.348089	up_reg	82	0.2482678
DNAH3	Q8TD57	24	0	1	0.165	0.733	3	84.86977	3.642484	up_reg	16	0.2479771
FUT2	Q10981	32	0	1	0.311	0.872	2	90.42101	2.453333	up_reg	560	0.2477669
NDUFA3	O95167	2	0	1	0.274	0.730	1	96.84498	2.073884	up_reg	15	0.2477448
LAMB3	Q13751	2	0	1	0.212	0.844	2	78.10768	4.685454	up_reg	288	0.2471542
LAMA5	O15230	2	3467	4	0.157	0.682	2	80.88889	2.244719	up_reg	154	0.2466009
NDUFB7	P17568	2	0	1	0.266	0.753	1	88.93270	2.055041	up_reg	31	0.2458810
LAMA5	O15230	2	3467	4	0.061	0.679	2	75.26612	2.244719	up_reg	154	0.2454009
ACOT4	Q8N9L9	3	0	1	0.140	0.740	1	96.46060	2.828725	up_reg	23	0.2452729
TYMP	P19971	46	0	1	0.402	0.833	2	93.01893	2.648306	up_reg	270	0.2437807
TXK	P42681	2	1520	2	0.210	0.743	1	80.40473	2.723460	up_reg	90	0.2437520
KIF2C	Q99661	2	8668	7	0.070	0.558	2	74.65762	4.503661	up_reg	295	0.2431291
APBB1IP	Q7Z5R6	2	5286	3	0.280	0.668	1	73.44023	2.145425	up_reg	56	0.2425592
IL23A	Q9NPF7	2	0	1	0.205	0.868	2	80.95746	2.267386	up_reg	706	0.2424748
ALG3	Q92685	6	0	1	0.084	0.800	1	89.19005	2.839320	up_reg	131	0.2420622
LAMA5	O15230	2	3467	4	0.172	0.670	2	84.35481	2.244719	up_reg	154	0.2418009
RBBP8	Q99708	2	4708	8	0.355	0.524	1	53.50791	2.260842	up_reg	287	0.2417188
VDR	P11473	2	0	1	0.284	0.966	1	84.69541	3.683154	up_reg	8882	0.2412780
SLC2A1	P11166	2	2279	3	0.190	0.839	1	89.61531	3.442262	up_reg	3562	0.2412211
DLGAP5	Q15398	2	4794	4	0.128	0.669	1	56.37102	5.302585	up_reg	180	0.2405725
HLA-DQA2	P01906	2	761	6	0.146	0.568	1	89.47761	4.305408	up_reg	88	0.2398315
SLC12A5	Q9H2X9	42	0	1	0.167	0.797	3	78.73929	2.764017	up_reg	143	0.2394734
MUC16	Q8WXI7	2	1521	3	0.180	0.798	1	55.96839	8.476038	up_reg	1352	0.2393358
SLC5A1	P13866	2	0	1	0.444	0.865	1	84.10975	6.574268	up_reg	812	0.2390450
DSP	P15924	2	2832	2	0.293	0.890	1	79.72187	4.716943	up_reg	5445	0.2388685
FCGR1A	P12314	2	26802	5	0.350	0.568	2	84.96186	3.117302	up_reg	253	0.2387424
BLNK	Q8WV28	2	80581	4	0.308	0.447	1	64.71740	2.938435	up_reg	282	0.2386891
NCAPH	Q15003	2	0	3	0.198	0.683	1	60.71979	5.188544	up_reg	71	0.2382705
EYA2	O00167	28	2	2	0.223	0.748	1	69.03617	6.536633	up_reg	130	0.2380527
TMEM102	Q8N9M5	48	0	1	0.236	0.666	1	74.64646	3.553872	up_reg	5	0.2378005
DNAH5	Q8TE73	24	0	1	0.137	0.802	1	88.53234	3.828651	up_reg	183	0.2375608
RET	P07949	2	3789	4	0.127	0.827	1	79.44206	2.801801	up_reg	11194	0.2366877
LAMA5	O15230	2	3467	4	0.026	0.656	1	82.86351	2.244719	up_reg	154	0.2362009
WNT7B	P56706	2	0	1	0.461	0.832	2	89.56172	7.353727	up_reg	427	0.2360861
KRT6A	P02538	2	969	5	0.307	0.631	1	69.50787	3.041425	up_reg	196	0.2359403
DNAH3	Q8TD57	24	0	1	0.127	0.700	3	86.03215	3.642484	up_reg	16	0.2347771
XRCC2	O43543	2	761	5	0.516	0.659	1	87.09828	3.236290	up_reg	430	0.2343857
DSC3	Q14574	2	0	1	0.135	0.793	1	74.81262	2.160385	up_reg	181	0.2341352
LMNB1	P20700	2	325	2	0.275	0.754	2	82.63466	3.288592	up_reg	199	0.2340999
KIF6	Q6ZMV9	2	0	12	0.091	0.302	0	71.56561	2.593490	up_reg	83	0.2334100
PROM1	O43490	2	335	2	0.171	0.857	2	85.89768	5.868539	up_reg	2840	0.2329564
PIK3CG	P48736	2	9360	4	0.145	0.681	2	88.42052	2.098934	up_reg	562	0.2329258
RYR1	P21817	2	1899	4	0.422	0.808	6	80.58427	3.086482	up_reg	7993	0.2321177
ASPM	Q8IZT6	2	8922	4	0.448	0.675	3	63.92800	4.312243	up_reg	510	0.2315291
WDR62	O43379	2	0	1	0.088	0.770	2	61.36502	3.041289	up_reg	124	0.2309319
CXCL16	Q9H2A7	2	40	2	0.204	0.808	2	65.97562	3.366446	up_reg	927	0.2308495
LAMC2	Q13753	2	0	1	0.153	0.822	1	74.86195	4.997825	up_reg	472	0.2304904
FGF18	O76093	2	620	2	0.380	0.771	2	87.67060	5.957364	up_reg	396	0.2303223
CIT	O14578	2	4278	2	0.129	0.882	1	70.15278	3.109393	up_reg	8634	0.2301055
BMP7	P18075	12	7	3	0.232	0.814	2	76.70694	7.157820	up_reg	3269	0.2297713
RGS19	P49795	2	0	1	0.119	0.740	2	79.47628	3.524701	up_reg	63	0.2296172
ASPM	Q8IZT6	2	8922	4	0.197	0.670	3	66.25757	4.312243	up_reg	510	0.2295291
CHAC1	Q9BUX1	17	0	1	0.391	0.775	1	86.16639	2.901424	up_reg	155	0.2293957
GPR19	Q15760	27	0	1	0.271	0.708	2	74.77012	5.197318	up_reg	30	0.2283877
DNAH3	Q8TD57	24	0	1	0.134	0.681	1	85.22852	3.642484	up_reg	16	0.2271771
DNAH5	Q8TE73	24	0	1	0.230	0.776	2	85.04038	3.828651	up_reg	183	0.2271608
PAK6	Q9NQU5	2	0	1	0.452	0.760	4	67.07498	3.389624	up_reg	123	0.2270601
NOTUM	Q6P988	2	0	1	0.466	0.800	1	84.58992	7.917860	up_reg	341	0.2268665
UNC5A	Q6ZN44	2	0	1	0.108	0.737	1	78.25560	5.877999	up_reg	71	0.2265372
MARVELD2	Q8N4S9	2	3133	5	0.305	0.564	1	67.20563	5.592913	up_reg	78	0.2264109
RAB27B	O00194	2	0	1	0.070	0.777	1	86.79901	2.886397	up_reg	230	0.2239298
FUT1	P19526	32	0	1	0.333	0.788	1	88.46001	2.677239	up_reg	317	0.2232279
CENPE	Q02224	2	1501	4	0.308	0.670	2	71.07051	2.847355	up_reg	436	0.2228167
RYR1	P21817	2	1899	4	0.176	0.784	3	82.30215	3.086482	up_reg	7993	0.2225177
KIF1A	Q12756	2	0	11	0.106	0.373	0	71.01825	4.710262	up_reg	351	0.2222732
CD109	Q6YHK3	2	761	2	0.287	0.734	2	81.37547	2.781852	up_reg	265	0.2220890
DNAH3	Q8TD57	24	0	1	0.115	0.668	1	84.68082	3.642484	up_reg	16	0.2219771
FOLR1	P15328	2	608	4	0.090	0.662	1	91.11366	9.610444	up_reg	357	0.2216913
TRIP13	Q15645	2	1521	3	0.249	0.677	2	86.97940	3.848280	up_reg	197	0.2216112
FBN2	P35556	12	7	3	0.177	0.700	2	74.88673	2.521524	up_reg	313	0.2215720
CLDN3	O15551	2	669	5	0.271	0.631	1	81.42759	10.441852	up_reg	485	0.2211545
GZMB	P10144	2	2279	3	0.347	0.774	1	92.52045	4.083414	up_reg	2459	0.2211340
LRP2	P98164	2	761	2	0.224	0.752	1	87.38054	4.927297	up_reg	452	0.2207911
PARD6B	Q9BYG5	2	3192	2	0.345	0.647	1	71.24402	3.304514	up_reg	40	0.2201530
POLQ	O75417	2	0	2	0.104	0.717	1	59.48627	3.988411	up_reg	184	0.2201409
RACGAP1	Q9H0H5	2	1421	5	0.133	0.584	2	69.86318	3.466668	up_reg	173	0.2196828
DNAH3	Q8TD57	24	0	1	0.199	0.662	1	78.29482	3.642484	up_reg	16	0.2195771
CBLC	Q9ULV8	2	102	2	0.215	0.744	1	81.16177	8.008650	up_reg	381	0.2194943
SMC4	Q9NTJ3	2	4021	6	0.294	0.533	3	81.89970	2.074392	up_reg	175	0.2189937
TMEM63C	Q9P1W3	2	0	1	0.125	0.649	1	74.57350	3.490019	up_reg	12	0.2186591
CD180	Q99467	15	0	1	0.355	0.747	1	93.23928	3.301753	up_reg	151	0.2186104
CYC1	P08574	2	0	1	0.109	0.817	1	86.38440	2.331383	up_reg	883	0.2185086
MGST2	Q99735	39	0	1	0.330	0.715	1	93.94066	2.026180	up_reg	69	0.2181868
SHCBP1	Q8NEM2	2	0	1	0.180	0.711	1	73.69646	2.980451	up_reg	65	0.2175260
TREM2	Q9NZC2	2	0	2	0.411	0.799	1	77.04992	3.818614	up_reg	1706	0.2174719
POSTN	Q15063	2	0	1	0.152	0.839	2	80.24478	2.937741	up_reg	1643	0.2174055
LRP2	P98164	2	761	2	0.346	0.742	1	82.33059	4.927297	up_reg	452	0.2167911
GRIN2A	Q12879	2	4542	3	0.064	0.686	1	60.41927	3.737127	up_reg	429	0.2165816
RAB6B	Q9NRW1	2	0	1	0.239	0.683	1	86.02474	2.332450	up_reg	35	0.2160010
TRPV4	Q9HBA0	2	761	2	0.132	0.803	5	72.00033	3.177434	up_reg	2211	0.2158796
CCR1	P32246	2	719	3	0.143	0.752	1	83.11436	2.538960	up_reg	1807	0.2153133
CMPK2	Q5EBM0	21	0	1	0.064	0.706	2	87.31019	3.113808	up_reg	67	0.2150495
SHISA9	B4DS77	2	0	1	0.277	0.654	1	56.95488	5.720736	up_reg	18	0.2146018
SYNE4	Q8N205	11	0	1	0.168	0.628	1	57.78246	4.109102	up_reg	9	0.2144468
CSPG5	O95196	2	0	1	0.081	0.686	1	52.88670	4.429149	up_reg	42	0.2143649
H2AC8	P04908	2	12365	8	0.384	0.231	0	91.08903	2.068346	up_reg	1	0.2133477
GINS4	Q9BRT9	2	0	2	0.324	0.635	1	90.74832	2.575322	up_reg	36	0.2130303
ACKR2	O00590	2	3092	3	0.220	0.621	2	80.01695	4.237197	up_reg	100	0.2119053
TNFSF15	O95150	2	0	1	0.272	0.775	2	82.11392	4.283946	up_reg	467	0.2118600
WAS	P42768	2	2279	3	0.258	0.437	1	70.12989	2.016246	up_reg	0	0.2109615
UNC5B	Q8IZJ1	2	6797	4	0.216	0.597	1	77.98145	2.185793	up_reg	231	0.2102958
CENPK	Q9BS16	2	0	3	0.253	0.599	1	81.70731	3.365918	up_reg	50	0.2101747
CD8A	P01732	2	558	3	0.263	0.692	1	79.23665	2.123590	up_reg	573	0.2094271
CXCR4	P61073	2	10567	8	0.122	0.585	1	82.80839	3.415298	up_reg	15921	0.2093435
FOXM1	Q08050	2	1527	4	0.173	0.701	1	51.07629	5.310591	up_reg	2251	0.2090775
SPC25	Q9HBM1	2	0	1	0.390	0.708	1	90.25548	4.349788	up_reg	106	0.2086137
MUC16	Q8WXI7	2	1521	3	0.177	0.720	2	77.36666	8.476038	up_reg	1352	0.2081358
RYR1	P21817	2	1899	4	0.194	0.748	1	75.79852	3.086482	up_reg	7993	0.2081177
DSP	P15924	2	2832	2	0.471	0.813	1	76.57581	4.716943	up_reg	5445	0.2080685
FYB1	O15117	2	0	1	0.418	0.698	1	58.39229	2.503950	up_reg	86	0.2079165
FUT3	P21217	30	0	1	0.263	0.734	2	90.59422	4.921716	up_reg	215	0.2078015
DLGAP3	O95886	2	0	1	0.282	0.648	1	50.70109	3.775359	up_reg	25	0.2071953
NCAPG	Q9BPX3	2	0	3	0.163	0.655	1	82.50230	4.802859	up_reg	252	0.2070111
ST14	Q9Y5Y6	51	0	1	0.160	0.771	2	81.25730	7.158208	up_reg	577	0.2068904
H4C3	P62805	2	0	1	0.336	0.581	1	90.43752	6.938438	up_reg	4	0.2067106
FBN2	P35556	12	7	3	0.076	0.662	1	73.45494	2.521524	up_reg	313	0.2063720
COL13A1	Q5TAT6	1	0	2	0.197	0.646	1	57.97463	2.870544	up_reg	75	0.2059408
PIGR	P01833	35	0	1	0.017	0.776	1	77.21791	3.975115	up_reg	702	0.2057654
CHST4	Q8NCG5	18	0	1	0.363	0.655	2	90.77228	5.171505	up_reg	34	0.2052506
KIF23	Q02241	2	5487	6	0.314	0.498	1	73.07353	3.446904	up_reg	207	0.2041465
SLC7A11	Q9UPY5	2	761	2	0.376	0.758	3	86.60983	2.106353	up_reg	1518	0.2038788
CDR2L	Q86X02	2	0	1	0.434	0.641	2	74.20117	3.691110	up_reg	26	0.2037929
GATA3	P23771	2	29626	9	0.110	0.426	1	58.31754	3.618532	up_reg	5363	0.2034283
PYCR3	Q53H96	47	0	1	0.416	0.600	1	94.81272	2.239585	up_reg	9	0.2032468
ADD2	P35612	2	761	2	0.203	0.639	4	66.27120	3.978666	up_reg	80	0.2030682
GPRIN2	O60269	2	0	1	0.172	0.634	1	50.28259	4.769083	up_reg	23	0.2028729
MX2	P20592	2	0	1	0.177	0.784	1	78.01712	2.755543	up_reg	1098	0.2018337
LGR5	O75473	37	3	2	0.267	0.766	4	80.74472	3.946516	up_reg	2020	0.2015804
ITGA3	P26006	2	2794	5	0.183	0.545	2	84.16933	2.090433	up_reg	228	0.2014026
ROMO1	P60602	2	636	2	0.413	0.649	3	78.13109	2.159277	up_reg	115	0.2011806
ITGB4	P16144	2	8018	6	0.154	0.505	1	69.97733	3.972681	up_reg	363	0.2011550
HOMER2	Q9NSB8	2	1521	3	0.431	0.599	2	89.11372	3.173158	up_reg	101	0.2009985
PCNA	P12004	2	4677	7	0.569	0.642	1	94.33015	2.104983	up_reg	25415	0.2007025
MPP7	Q5T2T1	2	322	2	0.114	0.606	1	81.02127	2.488989	up_reg	39	0.2005855
CD74	P04233	2	3917	5	0.198	0.605	1	70.67138	3.873722	up_reg	1184	0.2005588
BTC	P35070	2	2783	3	0.290	0.731	1	72.38943	2.703718	up_reg	3190	0.2004066
RYR1	P21817	2	1899	4	0.067	0.728	2	74.31304	3.086482	up_reg	7993	0.2001177
ZNF217	O75362	2	6359	7	0.240	0.445	1	50.34735	2.073407	up_reg	219	0.1998000
DNAH3	Q8TD57	24	0	1	0.286	0.612	4	84.67000	3.642484	up_reg	16	0.1995771
RNF43	Q68DV7	37	0	3	0.124	0.651	1	54.60221	2.425714	up_reg	369	0.1993438
MCM10	Q7L590	2	0	5	0.080	0.549	2	66.88891	4.376528	up_reg	231	0.1993275
KIF4A	O95239	2	1470	2	0.244	0.668	3	72.17122	5.153087	up_reg	226	0.1990995
ERBB3	P21860	2	19657	7	0.108	0.502	1	72.82537	4.895964	up_reg	2709	0.1990216
CDCA8	Q53HL2	2	6045	6	0.388	0.483	1	68.78919	4.987197	up_reg	205	0.1989932
PIERCE1	Q5BN46	2	0	6	0.223	0.365	0	76.89413	3.026062	up_reg	6	0.1982733
FANCA	O15360	2	2277	2	0.135	0.707	1	74.56587	2.596562	up_reg	687	0.1980021
HLA-DRA	P01903	2	0	4	0.277	0.653	1	89.58587	3.994244	up_reg	1221	0.1977404
EPPK1	P58107	2	0	1	0.182	0.634	2	80.54692	6.941326	up_reg	38	0.1951234
DCTPP1	Q9H773	21	0	1	0.339	0.616	1	85.40514	2.697626	up_reg	24	0.1950213
CDC25C	P30307	2	0	1	0.362	0.777	1	64.18249	6.227772	up_reg	1461	0.1944782
KRT17	Q04695	2	81	3	0.276	0.626	1	79.60908	6.228925	up_reg	271	0.1943558
CENPN	Q96H22	2	0	2	0.300	0.612	1	86.20997	2.369029	up_reg	68	0.1938832
CENPM	Q9NSP4	2	439	4	0.181	0.514	1	89.76468	4.526135	up_reg	49	0.1937023
FOLH1	Q04609	2	2288	4	0.322	0.643	1	94.01397	2.144560	up_reg	1490	0.1934041
CCL4L2	Q8NHW4	2	0	1	0.140	0.601	1	90.27970	2.125786	up_reg	18	0.1934018
BCAM	P50895	2	0	1	0.182	0.725	3	84.58449	4.415965	up_reg	425	0.1933609
ALPL	P05186	2	0	1	0.370	0.761	2	93.75407	4.455983	up_reg	1060	0.1931954
DNAH5	Q8TE73	24	0	1	0.169	0.690	3	86.65257	3.828651	up_reg	183	0.1927608
LRP2	P98164	2	761	2	0.348	0.681	2	78.34824	4.927297	up_reg	452	0.1923911
ATP2B2	Q01814	2	0	1	0.151	0.681	2	73.94863	4.507063	up_reg	155	0.1917957
SMAD1	Q15797	2	0	1	0.240	0.801	1	81.78024	2.105853	up_reg	3204	0.1915497
TEKT2	Q9UIF3	2	0	6	0.320	0.382	0	91.10427	3.432483	up_reg	16	0.1909104
DMTN	Q08495	2	0	1	0.221	0.641	1	64.63463	3.098244	up_reg	60	0.1907835
NRARP	Q7Z6K4	2	1520	2	0.142	0.584	1	82.92880	3.105494	up_reg	46	0.1906981
NEK2	P51955	2	7688	2	0.136	0.658	2	78.74819	6.921414	up_reg	489	0.1905342
RAD51	Q06609	2	4984	5	0.282	0.640	1	91.59067	3.625870	up_reg	5831	0.1904461
MRPL13	Q9BYD1	2	2181	4	0.371	0.481	1	93.49656	2.310295	up_reg	32	0.1892964
CD7	P09564	2	1521	3	0.383	0.699	2	77.62312	2.751900	up_reg	2691	0.1887548
MLF1	P58340	2	799	4	0.247	0.532	1	65.94371	2.278928	up_reg	110	0.1886195
TTC30B	Q8N4P2	55	0	1	0.170	0.535	2	93.27146	2.933139	up_reg	4	0.1883106
SLC44A4	Q53GD3	2	0	1	0.128	0.632	1	83.76549	4.642249	up_reg	56	0.1882661
IL1RAP	Q9NPH3	2	0	1	0.211	0.692	1	86.22484	3.030829	up_reg	257	0.1881654
EGLN3	Q9H6Z9	2	0	1	0.068	0.697	3	91.56092	3.193540	up_reg	295	0.1879722
IFI44L	Q53G44	2	1520	3	0.257	0.590	1	86.36570	2.148762	up_reg	185	0.1878079
CCDC6	Q16204	2	0	1	0.565	0.678	2	76.03680	2.126289	up_reg	199	0.1866299
CABP4	P57796	2	0	1	0.276	0.620	1	66.10069	2.568051	up_reg	49	0.1855575
IL2RG	P31785	2	2925	4	0.234	0.609	1	76.81580	2.149183	up_reg	1136	0.1849210
CENPE	Q02224	2	1501	4	0.235	0.575	2	73.06951	2.847355	up_reg	436	0.1848167
L1CAM	P32004	2	5550	4	0.068	0.631	1	79.35279	3.823699	up_reg	2439	0.1847902
RAD54L	Q92698	2	0	1	0.171	0.669	1	80.51223	4.209123	up_reg	180	0.1846232
C1QC	P02747	2	940	2	0.290	0.619	1	81.16742	2.927810	up_reg	159	0.1844248
DNAH5	Q8TE73	24	0	1	0.383	0.669	1	84.26657	3.828651	up_reg	183	0.1843608
PLAU	P00749	2	998	3	0.414	0.626	1	82.30347	3.727477	up_reg	569	0.1836847
RAB3D	O95716	48	0	1	0.185	0.662	2	85.15368	2.740453	up_reg	166	0.1831082
NETO2	Q8NC67	42	0	1	0.302	0.631	1	72.42280	2.079967	up_reg	77	0.1828595
NEIL3	Q8TAT5	2	1223	6	0.015	0.445	1	70.00855	5.418772	up_reg	151	0.1826614
THEM6	Q8WUY1	2	0	1	0.187	0.534	1	94.93291	3.578714	up_reg	6	0.1825400
CDK2AP2	O75956	16	0	1	0.476	0.603	1	75.74548	2.120070	up_reg	40	0.1819251
CRB3	Q9BUF7	2	0	1	0.297	0.700	1	70.34841	6.178867	up_reg	484	0.1812905
GPSM3	Q9Y4H4	2	0	1	0.281	0.570	1	71.62680	2.087401	up_reg	18	0.1810018
THY1	P04216	2	761	2	0.334	0.756	1	83.05667	3.086846	up_reg	6210	0.1806004
KCP	Q6ZWJ8	12	0	1	0.112	0.681	2	72.93541	4.945915	up_reg	315	0.1805286
BCAT1	P54687	10	0	1	0.358	0.674	1	95.00595	2.614531	up_reg	265	0.1804779
CDK2AP1	O14519	16	0	1	0.451	0.632	1	76.36776	3.230913	up_reg	92	0.1804520
RYR1	P21817	2	1899	4	0.064	0.677	3	82.11736	3.086482	up_reg	7993	0.1797177
STIL	Q15468	2	0	1	0.163	0.693	1	53.64950	3.519855	up_reg	469	0.1789920
OAS2	P29728	19	2	3	0.270	0.588	1	87.74127	4.206419	up_reg	278	0.1786521
ALDH3B1	P43353	5	0	2	0.048	0.550	1	96.26882	2.749792	up_reg	38	0.1781900
BLM	P54132	2	1899	5	0.161	0.616	1	60.95775	3.668059	up_reg	5420	0.1781841
CCR5	P51681	2	119	2	0.253	0.774	1	85.29439	2.420445	up_reg	10827	0.1781320
CAPG	P40121	2	0	1	0.313	0.665	1	86.70529	3.387519	up_reg	249	0.1778681
OSM	P13725	2	1111	2	0.107	0.721	1	79.62908	2.173526	up_reg	3150	0.1778664
USP18	Q9UMW8	2	0	1	0.065	0.678	1	84.05593	3.392279	up_reg	351	0.1776065
FBN3	Q75N90	12	0	1	0.161	0.603	1	71.82553	5.054065	up_reg	53	0.1775291
BAK1	Q16611	2	2279	3	0.535	0.654	2	81.54397	2.273926	up_reg	1896	0.1772822
CKAP2	Q8WWK9	19	0	1	0.332	0.615	2	59.53707	2.952651	up_reg	74	0.1770856
AMN	Q9BXJ7	2	0	1	0.320	0.745	1	80.93990	5.031542	up_reg	1960	0.1769911
ELMO3	Q96BJ8	2	0	1	0.169	0.567	2	89.19677	3.013380	up_reg	22	0.1767522
MMP9	P14780	2	4920	4	0.191	0.717	2	82.25628	5.237949	up_reg	34223	0.1762547
DSP	P15924	2	2832	2	0.212	0.733	3	80.80300	4.716943	up_reg	5445	0.1760685
B3GNT2	Q9NY97	2	0	1	0.183	0.592	1	91.28206	2.353972	up_reg	44	0.1760392
KIF18A	Q8NI77	2	2337	10	0.186	0.256	0	67.74104	4.341757	up_reg	144	0.1758631
TPX2	Q9ULW0	2	761	2	0.402	0.656	1	64.23851	6.263362	up_reg	684	0.1757905
KRT23	Q9C075	2	1409	6	0.182	0.382	0	78.43096	7.803255	up_reg	48	0.1757618
FBN2	P35556	12	7	3	0.118	0.585	1	70.32078	2.521524	up_reg	313	0.1755720
GINS3	Q9BRX5	2	2215	4	0.238	0.441	1	88.16138	2.227008	up_reg	28	0.1754010
HAVCR2	Q8TDQ0	2	1520	2	0.115	0.676	2	71.85756	2.594164	up_reg	1252	0.1750935
CD6	P30203	2	0	1	0.079	0.699	1	66.69789	2.141497	up_reg	697	0.1750793
DSCC1	Q9BVC3	2	0	1	0.206	0.558	1	92.16572	2.243598	up_reg	20	0.1746043
RSPO4	Q2I0M5	37	0	2	0.197	0.559	1	78.73711	3.739053	up_reg	61	0.1743906
WNT10A	Q9GZT5	2	0	1	0.100	0.672	1	80.83386	7.182905	up_reg	400	0.1731262
RYR1	P21817	2	1899	4	0.105	0.659	3	81.12296	3.086482	up_reg	7993	0.1725177
HOOK1	Q9UJC3	2	0	1	0.269	0.603	3	82.67534	3.529558	up_reg	73	0.1724998
CITED4	Q96RK1	2	761	2	0.279	0.537	1	61.06457	3.902872	up_reg	42	0.1723759
PTPN6	P29350	2	2507	6	0.243	0.507	1	86.41216	3.217645	up_reg	1532	0.1721658
RCOR2	Q8IZ40	2	0	1	0.110	0.597	1	68.12330	3.046027	up_reg	65	0.1719260
UBASH3B	Q8TF42	2	0	1	0.138	0.588	2	85.36864	2.937062	up_reg	54	0.1712362
CASP8	Q14790	2	5020	5	0.223	0.589	2	81.49031	2.275285	up_reg	5488	0.1710582
PACSIN1	Q9BY11	2	761	2	0.285	0.562	1	85.39394	2.524601	up_reg	88	0.1707648
IQGAP3	Q86VI3	2	0	1	0.181	0.604	2	79.62675	5.163314	up_reg	85	0.1705011
IGF2BP2	Q9Y6M1	2	761	2	0.107	0.640	1	77.75247	2.401479	up_reg	650	0.1702031
DSC2	Q02487	2	3552	2	0.275	0.600	1	76.56279	5.332860	up_reg	297	0.1701394
ERCC6L	Q2NKX8	2	761	2	0.048	0.546	1	62.79458	2.571255	up_reg	62	0.1698796
PCP4	P48539	44	0	1	0.348	0.623	1	77.79623	3.572944	up_reg	144	0.1697629
LDHA	P00338	2	0	2	0.089	0.690	1	96.06050	2.195336	up_reg	2225	0.1696345
GMNC	A6NCL1	2	0	1	0.280	0.572	1	59.65300	6.567087	up_reg	40	0.1695251
MRPL14	Q6P1L8	2	231	4	0.335	0.400	1	86.22027	2.510977	up_reg	12	0.1693457
OCLN	Q16625	2	4018	7	0.030	0.464	1	65.47618	3.942788	up_reg	1993	0.1693110
LSR	Q86X29	2	4740	5	0.029	0.531	2	57.32796	5.010835	up_reg	1449	0.1687587
PKM	P14618	2	3037	5	0.224	0.522	2	96.78672	2.561725	up_reg	1019	0.1686600
KRT15	P19012	2	4	4	0.359	0.513	1	77.14245	3.112879	up_reg	229	0.1684040
P2RY6	Q15077	43	0	1	0.257	0.563	1	85.89765	4.546917	up_reg	35	0.1680010
SIGLEC14	Q08ET2	2	0	1	0.311	0.576	1	83.53957	2.119134	up_reg	49	0.1679575
HLA-DRA	A0A0G2JMH6	2	0	4	0.196	0.578	1	89.93541	3.994244	up_reg	1221	0.1677404
FBN2	P35556	12	7	3	0.126	0.565	1	75.59208	2.521524	up_reg	313	0.1675720
DNAH5	Q8TE73	24	0	1	0.404	0.627	2	87.62569	3.828651	up_reg	183	0.1675608
KCNN4	O15554	2	761	2	0.429	0.632	1	84.85052	3.886967	up_reg	641	0.1672253
TEC	P42680	2	2277	4	0.096	0.634	1	85.88542	2.329341	up_reg	6593	0.1660599
BICDL2	A1A5D9	11	0	1	0.351	0.415	1	80.82586	5.705336	up_reg	0	0.1660000
C1QA	P02745	2	1659	2	0.216	0.597	1	82.87227	2.309558	up_reg	313	0.1657554
DNAH5	Q8TE73	24	0	1	0.238	0.621	1	83.61957	3.828651	up_reg	183	0.1651608
MAL2	Q969L2	2	0	1	0.336	0.619	1	84.15024	8.534437	up_reg	176	0.1649799
RPS6KA1	Q15418	2	3340	3	0.060	0.562	3	77.46253	2.996836	up_reg	451	0.1646935
VAV1	P15498	2	853	3	0.182	0.602	2	87.14542	2.680345	up_reg	1025	0.1645227
ASPM	Q8IZT6	2	8922	4	0.281	0.507	2	68.95596	4.312243	up_reg	510	0.1643291
ENKUR	Q8TC29	2	0	5	0.369	0.346	0	87.21706	2.841760	up_reg	12	0.1641257
NUF2	Q9BZD4	2	0	1	0.317	0.622	2	89.42833	4.636580	up_reg	201	0.1640711
CDH6	P55285	2	3554	3	0.178	0.502	1	78.76359	5.541725	up_reg	108	0.1636619
AQP5	P55064	2	761	2	0.392	0.643	1	93.50506	7.968789	up_reg	1158	0.1621963
CENPF	P49454	2	10672	3	0.399	0.524	2	72.41199	4.302935	up_reg	385	0.1611119
SMKR1	H3BMG3	2	0	1	0.229	0.430	1	70.64355	5.083228	up_reg	1	0.1609362
KIFC1	Q9BW19	2	2554	7	0.202	0.353	0	77.88326	3.454857	up_reg	186	0.1608721
DNAH3	Q8TD57	24	0	1	0.407	0.511	1	85.57752	3.642484	up_reg	16	0.1591771
NGEF	Q8N5V2	2	0	1	0.181	0.553	1	72.01310	2.849246	up_reg	50	0.1584414
MAP4K1	Q92918	2	0	1	0.100	0.553	2	69.28828	2.859794	up_reg	52	0.1578274
DNAH3	Q8TD57	24	0	1	0.093	0.507	1	88.96404	3.642484	up_reg	16	0.1575771
DEPDC1B	Q8WUY9	2	444	3	0.107	0.469	1	77.36351	4.803039	up_reg	54	0.1575205
CLSPN	Q9HAW4	2	7028	7	0.285	0.322	0	51.81036	5.405931	up_reg	151	0.1573320
ESRP1	Q6NXG1	2	0	1	0.187	0.604	1	78.06816	8.042375	up_reg	197	0.1571903
RAD54B	Q9Y620	2	0	1	0.092	0.573	1	71.80594	2.894284	up_reg	91	0.1570246
VAV3	Q9UKW4	2	68848	8	0.067	0.117	0	84.41551	4.547079	up_reg	321	0.1567345
CXCL17	Q6UXB2	2	11398	7	0.060	0.292	0	59.53315	7.541358	up_reg	104	0.1566597
SLC34A2	O95436	2	0	1	0.040	0.616	3	72.96990	7.493592	up_reg	287	0.1560096
LRP2	P98164	2	761	2	0.244	0.590	1	81.82381	4.927297	up_reg	452	0.1559911
KRT18	P05783	2	5320	3	0.125	0.530	1	80.29975	5.341706	up_reg	409	0.1559073
CD96	P40200	2	0	1	0.113	0.605	1	66.54424	2.031664	up_reg	234	0.1548558
MYBL2	P10244	2	0	1	0.066	0.633	1	58.45051	6.939571	up_reg	478	0.1546892
SORT1	Q99523	2	2539	6	0.176	0.394	0	83.49614	2.686299	up_reg	283	0.1539170
ECT2	Q9H8V3	2	463	3	0.116	0.537	1	71.66219	4.589366	up_reg	384	0.1536841
EPPK1	P58107	2	0	1	0.206	0.530	2	83.08865	6.941326	up_reg	38	0.1535234
CYRIB	Q9NUQ9	2	0	1	0.134	0.494	1	92.17381	2.720870	up_reg	15	0.1533448
BARX2	Q9UMQ3	2	0	1	0.238	0.548	1	66.35156	7.021298	up_reg	61	0.1533239
MPZL3	Q6UWV2	40	0	1	0.289	0.513	1	80.77116	2.509616	up_reg	25	0.1531953
LAMA5	O15230	2	3467	4	0.132	0.448	1	83.31297	2.244719	up_reg	154	0.1530009
CDK5	Q00535	2	4541	5	0.253	0.522	1	91.44164	2.814439	up_reg	3067	0.1529490
ORC6	Q9Y5N6	2	4900	4	0.216	0.425	1	81.54463	3.385301	up_reg	101	0.1522584
TREM1	Q9NP99	2	0	1	0.034	0.660	1	71.42913	3.025812	up_reg	1118	0.1519459
RYR1	P21817	2	1899	4	0.271	0.606	1	82.39230	3.086482	up_reg	7993	0.1513177
KCTD1	Q719H9	2	0	1	0.380	0.519	1	87.09265	3.190517	up_reg	35	0.1504010
CEBPA	P49715	2	18094	5	0.467	0.453	1	63.67368	3.364331	up_reg	1906	0.1497578
CENPE	Q02224	2	1501	4	0.168	0.487	1	72.31956	2.847355	up_reg	436	0.1496167
TNFRSF11B	O00300	2	0	1	0.349	0.688	1	87.00873	4.469606	up_reg	2628	0.1495119
CXCL14	O95715	2	2123	5	0.298	0.447	1	85.46693	2.064284	up_reg	483	0.1494247
TPD52	P55327	2	761	5	0.350	0.412	1	68.17637	4.269727	up_reg	183	0.1491719
CLDN9	O95484	2	0	6	0.387	0.320	0	81.18086	7.555719	up_reg	51	0.1482648
NDC80	O14777	2	2922	3	0.161	0.532	2	78.60958	4.044795	up_reg	592	0.1478410
S100A4	P26447	2	7702	4	0.313	0.516	1	85.18673	3.072037	up_reg	1705	0.1471726
LTF	P02788	2	2076	3	0.410	0.569	1	95.06001	5.560156	up_reg	1484	0.1469387
CD2	P06729	2	97	4	0.375	0.633	2	78.29759	3.177594	up_reg	18110	0.1468275
RYR1	P21817	2	1899	4	0.190	0.592	1	83.96940	3.086482	up_reg	7993	0.1457177
NOS1AP	O75052	2	0	1	0.211	0.579	1	66.16135	2.421510	up_reg	221	0.1453641
CENPF	P49454	2	10672	3	0.437	0.484	2	70.99553	4.302935	up_reg	385	0.1451119
PTPN3	P26045	2	0	1	0.087	0.538	1	73.60570	2.860009	up_reg	82	0.1446678
E2F8	A0AVK6	2	0	1	0.140	0.562	1	53.69316	6.360635	up_reg	151	0.1446104
SELL	P14151	2	714	2	0.321	0.670	1	85.32516	2.655413	up_reg	6836	0.1446093
ZC2HC1C	Q53FD0	55	0	1	0.370	0.403	1	61.17503	2.306638	up_reg	2	0.1436643
RAB3IP	Q96QF0	48	1	2	0.090	0.453	1	72.31525	2.494769	up_reg	30	0.1430557
EVPL	Q92817	2	0	1	0.174	0.499	1	73.17542	5.384071	up_reg	34	0.1428506
PTTG1	O95997	2	3399	3	0.339	0.504	1	64.54399	5.620004	up_reg	437	0.1420689
EPPK1	P58107	2	0	1	0.114	0.501	1	79.25178	6.941326	up_reg	38	0.1419234
APOBEC3B	Q9UH17	2	0	1	0.283	0.593	1	88.33103	4.139712	up_reg	399	0.1415661
ENHO	Q6UWT2	27	0	1	0.408	0.561	2	75.10782	3.532277	up_reg	183	0.1411608
LEF1	Q9UJU2	2	4131	5	0.140	0.477	1	57.83920	3.139927	up_reg	2086	0.1405903
DNAH5	Q8TE73	24	0	1	0.380	0.558	1	86.10504	3.828651	up_reg	183	0.1399608
EGFL6	Q8IUX8	26	0	1	0.125	0.526	1	67.15563	6.860705	up_reg	84	0.1394878
LAIR1	Q6GTX8	2	174	2	0.416	0.521	1	71.90481	2.172930	up_reg	216	0.1394103
MUC5B	Q9HC84	2	1020	3	1.024	0.544	1	81.82964	5.737039	up_reg	1207	0.1389234
DSP	P15924	2	2832	2	0.400	0.639	1	76.99875	4.716943	up_reg	5445	0.1384685
DNAH3	Q8TD57	24	0	1	0.143	0.459	1	85.20082	3.642484	up_reg	16	0.1383771
CXCR3	P49682	2	1658	3	0.210	0.590	1	80.64541	4.557329	up_reg	4275	0.1379388
EPPK1	P58107	2	0	1	0.112	0.491	2	82.39167	6.941326	up_reg	38	0.1379234
HLA-DMB	P28068	2	0	2	0.451	0.541	1	89.04596	2.973875	up_reg	427	0.1363528
TNFRSF9	Q07011	2	761	2	0.306	0.548	2	81.76231	5.502102	up_reg	554	0.1359496
SLPI	P03973	2	0	1	0.442	0.612	1	84.39588	7.842239	up_reg	928	0.1357160
NDUFA4L2	Q9NRX3	2	9789	8	0.201	0.175	0	84.63933	2.341067	up_reg	53	0.1351438
NELL2	Q99435	14	0	1	0.254	0.523	1	80.32717	2.349571	up_reg	103	0.1350677
COL23A1	Q86Y22	1	0	2	0.185	0.433	1	60.28518	4.830819	up_reg	30	0.1350544
MYL11	Q96A32	2	761	2	0.286	0.293	0	84.57639	3.638218	up_reg	0	0.1348111
IL2RB	P14784	2	377	2	0.064	0.528	1	65.81703	3.612277	up_reg	374	0.1337307
CCL4	P13236	2	2410	3	0.270	0.626	1	88.97642	3.213667	up_reg	14603	0.1336666
SH3BGRL3	Q9H299	44	0	1	0.301	0.475	1	96.43171	2.275968	up_reg	34	0.1332506
CENPF	P49454	2	10672	3	0.416	0.452	1	70.50561	4.302935	up_reg	385	0.1323119
TK1	P04183	2	28	2	0.284	0.554	2	82.30998	5.569907	up_reg	778	0.1320283
SERPINA1	P01009	2	20309	6	0.431	0.336	0	89.00521	4.107159	up_reg	1052	0.1318528
CKS1B	P61024	2	9359	3	0.172	0.423	1	92.17249	2.929388	up_reg	191	0.1302292
UBE2C	O00762	2	23230	6	0.355	0.286	0	89.69871	6.912778	up_reg	434	0.1295887
PTPRF	P10586	2	0	1	0.303	0.521	3	82.86021	2.388058	up_reg	139	0.1295230
CLIC5	Q9NZA1	2	760	2	0.184	0.454	1	68.21008	5.435746	up_reg	79	0.1292653
TM4SF1	P30408	2	0	1	0.246	0.523	1	81.27962	2.530357	up_reg	151	0.1290104
BCL11A	Q9H165	2	0	1	0.176	0.584	3	52.46475	5.681517	up_reg	706	0.1288748
NAA38	Q9BRA0	2	0	1	0.488	0.435	1	79.30929	2.165583	up_reg	16	0.1287771
EXO1	Q9UQ84	2	0	2	0.203	0.552	1	63.63935	4.665404	up_reg	924	0.1284516
CA9	Q16790	2	761	2	0.253	0.580	2	76.98377	4.198252	up_reg	2015	0.1281606
CNKSR1	Q969H4	2	0	1	0.212	0.463	1	68.49088	2.403831	up_reg	35	0.1280010
CLDN4	O14493	2	2764	6	0.511	0.360	0	84.52154	7.966261	up_reg	627	0.1279296
TLR7	Q9NYK1	54	0	1	0.198	0.657	4	87.54334	3.806294	up_reg	4757	0.1276430
EPPK1	P58107	2	0	1	0.303	0.465	1	81.46403	6.941326	up_reg	38	0.1275234
EPPK1	P58107	2	0	1	0.325	0.465	1	80.08462	6.941326	up_reg	38	0.1275234
HOXB6	P17509	2	0	3	0.098	0.426	1	66.54839	5.256411	up_reg	118	0.1274504
ZBP1	Q9H171	2	0	1	0.155	0.556	1	55.84276	4.315149	up_reg	389	0.1271702
EPPK1	P58107	2	0	1	0.164	0.464	1	78.69683	6.941326	up_reg	38	0.1271234
TNFRSF13C	Q96RJ3	2	388	2	0.223	0.511	1	64.47587	2.730865	up_reg	371	0.1270726
MICB	Q29980	2	117	2	0.152	0.538	1	78.97880	2.653896	up_reg	735	0.1266450
KCNJ11	Q14654	2	0	1	0.126	0.592	1	84.56523	2.949554	up_reg	1019	0.1262244
POLR2F	P61218	2	3038	7	0.081	0.195	0	79.10277	4.942004	up_reg	32	0.1259599
MRPL15	Q9P015	2	0	2	0.439	0.396	0	91.01003	2.252783	up_reg	21	0.1257284
SPON1	Q9HCB6	2	761	2	0.074	0.461	1	77.42394	3.386911	up_reg	119	0.1255946
CENPW	Q5EE01	2	0	4	0.310	0.353	0	89.69919	3.831944	up_reg	60	0.1255835
ZNF726	A6NNF4	56	0	1	0.407	0.377	0	70.98692	2.195829	up_reg	4	0.1251106
GZMA	P12544	2	0	1	0.340	0.564	2	91.46294	2.555949	up_reg	557	0.1246525
FBN3	Q75N90	12	0	1	0.191	0.470	1	74.68523	5.054065	up_reg	53	0.1243291
RYR1	P21817	2	1899	4	0.107	0.537	2	84.48735	3.086482	up_reg	7993	0.1237177
LPAR3	Q9UBY5	2	0	1	0.018	0.503	1	81.89258	4.654211	up_reg	129	0.1235059
MUC16	Q8WXI7	2	1521	3	0.129	0.507	3	61.67421	8.476038	up_reg	1352	0.1229358
KRT5	P13647	2	0	4	0.423	0.438	1	68.77450	4.040272	up_reg	612	0.1227520
LINGO1	Q96FE5	2	0	1	0.222	0.530	2	86.97018	3.398463	up_reg	268	0.1226989
TYMS	P04818	2	0	2	0.380	0.529	1	94.13606	2.197956	up_reg	818	0.1211943
LLGL2	Q6P1M3	2	761	2	0.114	0.412	2	85.39241	2.400335	up_reg	46	0.1209562
FBN2	P35556	12	7	3	0.146	0.448	1	73.40911	2.521524	up_reg	313	0.1207720
EPPK1	P58107	2	0	1	0.164	0.448	1	81.31179	6.941326	up_reg	38	0.1207234
CD24	P25063	2	0	1	0.228	0.632	1	63.89011	8.713693	up_reg	4011	0.1203651
NDUFS8	O00217	2	0	1	0.547	0.470	1	89.19101	2.656440	up_reg	70	0.1199604
VAMP8	Q9BV40	2	3785	5	0.286	0.350	0	90.45868	4.647834	up_reg	317	0.1193917
NRG4	Q8WWG1	2	0	3	0.403	0.409	1	78.48852	2.336379	up_reg	130	0.1191169
BRCA2	P51587	2	32217	9	0.072	0.246	0	55.07728	2.245119	up_reg	14293	0.1189992
SCNN1A	P37088	2	0	1	0.225	0.525	1	75.79274	5.496125	up_reg	300	0.1189049
FGFR3	P22607	2	2641	4	0.127	0.488	1	75.36964	3.476785	up_reg	3416	0.1186048
FAM83D	Q9H4H8	2	0	1	0.140	0.459	1	64.42717	5.053814	up_reg	58	0.1185156
GIPC1	O14908	2	0	1	0.347	0.501	1	81.65762	2.472014	up_reg	174	0.1179613
PCDH19	Q8TAB3	2	0	1	0.156	0.512	1	68.74772	2.531005	up_reg	242	0.1171214
ESRRG	P62508	2	0	1	0.247	0.522	1	76.18379	3.288085	up_reg	338	0.1158072
MYB	P10242	2	0	1	0.162	0.652	1	59.19859	5.712612	up_reg	9106	0.1152805
DSP	P15924	2	2832	2	0.224	0.581	1	80.17210	4.716943	up_reg	5445	0.1152685
HLA-DRB5	Q30154	2	206	6	0.385	0.330	0	88.27784	2.841964	up_reg	548	0.1149010
TNNC1	P63316	2	0	1	0.394	0.480	1	79.95947	2.859371	up_reg	127	0.1145534
PRKCQ	Q04759	2	0	1	0.202	0.549	2	79.85454	2.711625	up_reg	721	0.1145397
RYR1	P21817	2	1899	4	0.269	0.513	1	80.35160	3.086482	up_reg	7993	0.1141177
HLA-DQA1	P01909	2	0	6	0.385	0.380	0	88.71415	4.559819	up_reg	1989	0.1140901
ALOX5AP	P20292	7	0	1	0.299	0.534	1	89.60768	2.082130	up_reg	517	0.1138398
MUC5B	Q9HC84	2	1020	3	0.161	0.481	1	60.93242	5.737039	up_reg	1207	0.1137234
CDH1	P12830	2	23050	9	0.076	0.224	0	79.89055	4.933467	up_reg	5706	0.1134782
NCF1	P14598	2	1234	2	0.241	0.472	1	83.56633	2.397018	up_reg	369	0.1126085
ALK	Q9UM73	2	761	2	0.087	0.620	3	67.27647	4.194048	up_reg	14702	0.1124457
CXCL1	P09341	2	1755	4	0.207	0.499	1	82.27114	3.026079	up_reg	6221	0.1123390
JPH1	Q9HDC5	2	0	1	0.144	0.413	1	66.01235	2.552469	up_reg	27	0.1120124
FBP1	P09467	3	1	2	0.373	0.490	1	94.36528	3.028902	up_reg	548	0.1119800
EPPK1	P58107	2	0	1	0.320	0.425	1	79.71663	6.941326	up_reg	38	0.1115234
SYNGR3	O43761	2	0	1	0.202	0.389	0	80.73087	2.967295	up_reg	15	0.1113448
ANXA3	P12429	2	0	1	0.484	0.487	1	96.34132	4.071198	up_reg	190	0.1109648
ITGB6	P18564	2	0	1	0.064	0.481	1	83.51907	5.417491	up_reg	168	0.1105181
PPARGC1B	Q86YN6	2	0	1	0.075	0.497	1	50.96161	2.110510	up_reg	252	0.1104777
FBXL16	Q8N461	31	0	1	0.345	0.386	0	84.45983	4.344689	up_reg	15	0.1101448
WNT7A	O00755	2	761	2	0.309	0.489	1	88.75607	9.734620	up_reg	673	0.1092489
DNAH5	Q8TE73	24	0	1	0.261	0.481	1	83.92766	3.828651	up_reg	183	0.1091608
TNNI1	P19237	2	1141	3	0.252	0.365	0	78.08491	4.029660	up_reg	90	0.1087483
STXBP2	Q15833	2	761	2	0.122	0.430	1	90.53373	2.772280	up_reg	160	0.1085032
NUDT14	O95848	2	0	1	0.254	0.354	0	94.66943	2.521537	up_reg	7	0.1084086
MCM2	P49736	2	0	2	0.139	0.522	3	76.52259	2.384586	up_reg	1556	0.1081400
KNSTRN	Q9Y448	2	0	1	0.402	0.413	1	68.64854	2.082946	up_reg	35	0.1080010
DNAH5	Q8TE73	24	0	1	0.239	0.477	3	83.80640	3.828651	up_reg	183	0.1075608
EPPK1	P58107	2	0	1	0.175	0.414	2	81.08339	6.941326	up_reg	38	0.1071234
MUC5B	Q9HC84	2	1020	3	0.316	0.464	1	54.54405	5.737039	up_reg	1207	0.1069234
TTC30A	Q86WT1	55	1	2	0.265	0.280	0	93.50527	2.528791	up_reg	3	0.1065403
WNT2	P09544	2	688	2	0.340	0.478	1	88.00264	2.283292	up_reg	612	0.1062725
CLDN16	Q9Y5I7	2	23	6	0.140	0.247	0	69.10264	9.609066	up_reg	118	0.1058790
DEPDC1	Q5TB30	2	0	1	0.111	0.445	1	61.05036	5.973836	up_reg	91	0.1058246
ASPM	Q8IZT6	2	8922	4	0.161	0.360	0	63.08517	4.312243	up_reg	510	0.1055291
MUC16	Q8WXI7	2	1521	3	0.089	0.463	1	74.65565	8.476038	up_reg	1352	0.1053358
ASPM	Q8IZT6	2	8922	4	0.271	0.359	0	70.40001	4.312243	up_reg	510	0.1051291
CENPF	P49454	2	10672	3	0.219	0.384	0	70.83409	4.302935	up_reg	385	0.1051119
NECTIN4	Q96NY8	2	761	2	0.112	0.450	1	78.89692	6.633982	up_reg	334	0.1048077
IL12RB1	P42701	2	0	1	0.192	0.495	1	77.25548	2.276120	up_reg	347	0.1045889
LSM4	Q9Y4Z0	2	761	2	0.486	0.382	0	77.63958	2.319798	up_reg	62	0.1042796
SLC7A1	P30825	2	1521	3	0.129	0.387	0	81.62643	2.506855	up_reg	219	0.1039294
OTUB2	Q96DC9	2	0	1	0.314	0.410	1	94.26903	2.133800	up_reg	43	0.1035979
RASSF7	Q02833	2	0	1	0.307	0.409	1	74.57045	3.298786	up_reg	42	0.1035649
TONSL	Q96HA7	2	0	3	0.187	0.335	0	76.48871	2.768622	up_reg	54	0.1033695
DTL	Q9NZJ0	2	0	1	0.101	0.511	2	63.43932	4.651305	up_reg	625	0.1016171
HOXB5	P09067	2	3032	4	0.277	0.330	0	63.73337	5.327041	up_reg	195	0.1015150
CD200R1	Q8TD46	2	0	1	0.414	0.475	1	76.65146	2.587670	up_reg	259	0.1012421
MYH14	Q7Z406	2	0	1	0.245	0.442	1	74.65097	6.665417	up_reg	115	0.1009246
RUNX3	Q13761	2	9057	5	0.403	0.350	0	62.21557	4.881702	up_reg	1560	0.1005386
S100A1	P23297	2	1966	2	0.469	0.452	2	82.78688	5.000700	up_reg	521	0.1000235
PCDH7	O60245	2	0	1	0.174	0.439	1	76.89920	2.341810	up_reg	114	0.0998628
MARS2	Q96GW9	4	0	1	0.093	0.386	0	89.64912	2.313493	up_reg	31	0.0990810
GAPDH	P04406	2	8828	5	0.345	0.413	1	98.17071	2.454683	up_reg	8509	0.0983848
TYROBP	O43914	2	4887	4	0.285	0.361	0	64.54930	3.691863	up_reg	602	0.0982793
EPPK1	P58107	2	0	1	0.229	0.391	0	80.87318	6.941326	up_reg	38	0.0979234
OAS3	Q9Y6K5	19	0	2	0.107	0.413	2	86.81560	2.988047	up_reg	199	0.0972965
ASF1B	Q9NVP2	2	750	3	0.391	0.346	0	85.64720	5.643420	up_reg	113	0.0970663
CGN	Q9P2M7	2	0	1	0.153	0.528	1	70.80985	2.903039	up_reg	1290	0.0968636
CD86	P42081	2	4201	4	0.351	0.479	1	79.80962	2.860159	up_reg	12042	0.0968335
CTNNA2	P26232	2	0	1	0.082	0.423	1	80.50284	4.876683	up_reg	94	0.0965124
FBN3	Q75N90	12	0	1	0.179	0.400	1	75.00891	5.054065	up_reg	53	0.0963291
RHOV	Q96L33	2	6094	5	0.401	0.233	0	85.68690	3.846255	up_reg	86	0.0961458
DOK7	Q18PE1	2	0	1	0.150	0.450	1	66.42315	5.786555	up_reg	193	0.0959161
E2F3	O00716	2	761	2	-0.002	0.462	1	61.41248	2.643044	up_reg	789	0.0959141
COX7B	P24311	2	0	2	0.404	0.355	0	90.27638	2.360595	up_reg	50	0.0959081
E2F1	Q01094	2	10918	7	0.159	0.295	0	63.73504	2.635547	up_reg	5117	0.0952280
OAS1	P00973	19	0	2	0.310	0.455	1	84.21378	3.083827	up_reg	681	0.0945161
KRT80	Q6KB66	2	0	5	0.411	0.209	0	76.76731	5.731736	up_reg	32	0.0944565
EMB	Q6PCB8	2	2277	2	0.381	0.512	1	78.47557	2.398641	up_reg	3502	0.0940230
GRHL1	Q9NZI5	33	0	1	0.206	0.399	0	68.95769	3.061285	up_reg	64	0.0929697
TFF3	Q07654	2	761	2	0.405	0.466	1	80.13800	2.167937	up_reg	1057	0.0928517
PLS1	Q14651	2	0	2	0.067	0.423	1	87.84443	4.693588	up_reg	352	0.0922279
GNL3L	Q9NVN8	13	0	1	0.138	0.362	0	72.84667	3.254326	up_reg	26	0.0921929
SPN	P16150	2	0	1	0.297	0.552	1	53.31901	2.356560	up_reg	3261	0.0916684
FOXP4	Q8IVH2	2	0	1	0.159	0.427	1	59.23848	2.392759	up_reg	143	0.0914734
RAD51AP1	Q96B01	2	333	5	0.122	0.242	0	58.79844	4.168726	up_reg	95	0.0910252
GRHL2	Q6ISB3	33	0	1	0.092	0.442	1	67.86823	7.179971	up_reg	231	0.0898608
EPPK1	P58107	2	0	1	0.118	0.370	0	82.67139	6.941326	up_reg	38	0.0895234
MYO5B	Q9ULV0	41	0	1	0.304	0.432	1	75.50398	3.621753	up_reg	185	0.0893882
RPL39L	Q96EH5	2	0	1	0.319	0.343	0	94.09941	3.915386	up_reg	19	0.0893830
UHRF1	Q96T88	2	16747	6	0.210	0.221	0	81.26714	4.080136	up_reg	696	0.0880184
PDLIM1	O00151	2	3755	2	0.426	0.336	0	70.20826	2.021676	up_reg	70	0.0876870
MAFB	Q9Y5Q3	2	1384	3	0.207	0.393	0	64.85064	2.002627	up_reg	701	0.0876390
WDR93	Q6P2C0	2	3795	6	0.147	0.041	0	76.99177	2.267609	up_reg	2	0.0869072
SFN	P31947	2	73299	6	0.296	0.091	0	93.38504	5.327039	up_reg	2478	0.0859461
CENPF	P49454	2	10672	3	0.173	0.336	0	71.95028	4.302935	up_reg	385	0.0859119
GNLY	P22749	2	761	2	0.379	0.410	1	78.38773	2.553860	up_reg	401	0.0858975
RABIF	P47224	2	0	1	0.330	0.348	0	89.03728	2.438201	up_reg	29	0.0849111
CKMT1B	P12532	8	0	1	0.049	0.325	0	90.05943	4.787301	up_reg	16	0.0847771
FKBP1C	Q5VVH2	2	0	1	0.363	0.239	0	95.38909	2.614579	up_reg	1	0.0845362
DSP	P15924	2	2832	2	0.580	0.504	2	77.45712	4.716943	up_reg	5445	0.0844685
OASL	Q15646	2	0	2	0.340	0.392	0	92.28700	5.308283	up_reg	267	0.0842250
MZB1	Q8WU39	29	0	1	0.198	0.380	0	84.76435	3.553878	up_reg	69	0.0841868
CDKN2A	P42771	2	761	3	0.396	0.503	2	75.59437	8.463693	up_reg	13656	0.0834904
DARS2	Q6PI48	23	0	1	0.102	0.394	0	88.75458	2.268401	up_reg	103	0.0834677
LAMA5	O15230	2	3467	4	0.171	0.274	0	83.83144	2.244719	up_reg	154	0.0834009
TACC3	Q9Y6A5	2	727	2	0.259	0.400	1	58.34000	3.743070	up_reg	369	0.0831793
H2AC11	P0C0S8	2	0	1	0.416	0.234	0	91.30357	4.077578	up_reg	1	0.0825362
PTK6	Q13882	2	5745	4	0.137	0.283	0	89.16695	2.218046	up_reg	248	0.0822616
CEP55	Q53EZ4	2	640	2	0.284	0.386	0	82.79305	5.920805	up_reg	274	0.0822077
BUB1	O43683	2	1521	3	0.138	0.403	1	64.12427	4.789490	up_reg	1284	0.0821589
PRKCZ	Q05513	2	4419	5	0.054	0.219	0	80.53423	2.469978	up_reg	130	0.0819342
CDKN3	Q16667	2	0	1	0.472	0.413	1	91.05949	4.403471	up_reg	184	0.0818743
CFAP90	A4QMS7	2	0	1	0.256	0.204	0	75.36202	2.657168	up_reg	0	0.0816000
MSX1	P28360	2	1056	2	0.339	0.442	1	65.80064	2.501717	up_reg	1214	0.0814092
CKMT1A	P12532	8	0	1	0.049	0.325	0	90.05943	6.417662	up_reg	20	0.0814043
MUC16	Q8WXI7	2	1521	3	0.196	0.403	1	73.85441	8.476038	up_reg	1352	0.0813358
CLDN1	O95832	2	15884	6	0.392	0.231	0	84.70039	2.942980	up_reg	1280	0.0812329
IFIT2	P09913	2	0	1	0.301	0.424	1	88.96310	2.135232	up_reg	254	0.0811520
NOL4L	Q96MY1	2	0	1	0.262	0.302	0	62.45976	2.745127	up_reg	11	0.0811367
BOP1	Q14137	13	0	1	0.149	0.393	0	80.78432	2.165984	up_reg	120	0.0806511
CADM3	Q8N126	2	0	1	0.379	0.350	0	84.61009	2.432258	up_reg	41	0.0803405
RYR1	P21817	2	1899	4	0.093	0.428	1	84.72206	3.086482	up_reg	7993	0.0801177
DNAH5	Q8TE73	24	0	1	0.170	0.408	1	87.45737	3.828651	up_reg	183	0.0799608
IKBKE	Q14164	2	123	2	0.192	0.440	1	88.66232	2.971049	up_reg	1238	0.0791392
OLR1	P78380	2	0	1	0.388	0.476	1	87.40709	4.414247	up_reg	1066	0.0791054
SPC24	Q8NBT2	2	0	1	0.345	0.372	0	91.39337	4.999440	up_reg	79	0.0788554
PNP	P00491	46	1	2	0.189	0.507	1	94.05180	2.680894	up_reg	6777	0.0786628
CA12	O43570	2	0	1	0.413	0.434	1	88.39335	3.797709	up_reg	388	0.0784112
PSMB3	P49720	2	0	1	0.327	0.330	0	97.37889	2.223922	up_reg	28	0.0782523
RFXANK	O14593	2	0	1	0.338	0.374	0	79.70517	2.042703	up_reg	87	0.0781341
RGS1	Q08116	2	0	1	0.315	0.422	1	81.96646	2.074463	up_reg	310	0.0771832
ALOX5	P09917	7	0	1	0.355	0.442	1	97.15666	2.088381	up_reg	521	0.0769170
PPP1R16B	Q96T49	2	0	1	0.190	0.344	0	70.84716	2.196990	up_reg	45	0.0764884
PRKCI	P41743	2	38	2	0.145	0.340	0	82.48188	2.360984	up_reg	118	0.0764309
EPPK1	P58107	2	0	1	0.491	0.336	0	81.56797	6.941326	up_reg	38	0.0759234
MISP	Q8IVT2	2	1139	2	0.227	0.353	0	54.69582	5.997961	up_reg	192	0.0752787
EPHA1	P21709	2	4697	4	0.216	0.277	0	80.64237	4.441436	up_reg	315	0.0747575
EPPK1	P58107	2	0	1	0.203	0.333	0	82.96788	6.941326	up_reg	38	0.0747234
CCNE1	P24864	2	4140	5	0.101	0.284	0	79.97658	5.446912	up_reg	1061	0.0741847
EPPK1	P58107	2	0	1	0.151	0.330	0	82.02849	6.941326	up_reg	38	0.0735234
UBE2T	Q9NPD8	2	0	1	0.273	0.383	0	86.02709	5.344372	up_reg	147	0.0734360
CCL5	P13501	2	9296	3	0.141	0.432	1	89.33505	3.279413	up_reg	8493	0.0732623
CADM1	Q9BY67	2	1434	3	0.332	0.349	0	81.61015	2.022739	up_reg	579	0.0731482
GINS2	Q9Y248	2	0	2	0.258	0.318	0	93.40448	2.817382	up_reg	85	0.0727677
CD52	P31358	2	0	1	0.352	0.466	1	68.58155	2.633993	up_reg	1238	0.0727199
LRFN4	Q6PJG9	2	761	2	0.222	0.253	0	78.08724	2.052951	up_reg	20	0.0702153
CDCA5	Q96FF9	2	0	1	0.258	0.376	0	63.50505	4.692774	up_reg	156	0.0696938
TNFRSF4	P43489	2	0	1	0.295	0.427	1	77.22429	2.183879	up_reg	644	0.0675398
EPPK1	P58107	2	0	1	0.246	0.315	0	79.72240	6.941326	up_reg	38	0.0675234
ZWINT	O95229	2	4	2	0.268	0.320	0	79.45827	3.872467	up_reg	129	0.0669775
PTPRJ	Q12913	2	0	1	0.406	0.384	0	78.57151	2.285213	up_reg	229	0.0667990
HLA-DRB1	P01911	2	4530	4	0.309	0.398	0	89.12497	3.221560	up_reg	10656	0.0667934
LAMTOR2	Q9Y2Q5	2	0	1	0.338	0.335	0	91.48972	2.013323	up_reg	73	0.0652998
FCGR3A	P08637	2	622	3	0.351	0.341	0	85.63872	2.760408	up_reg	763	0.0645424
GMIP	Q9P107	2	0	1	0.172	0.303	0	70.24573	2.022512	up_reg	34	0.0644506
GINS1	Q14691	2	0	2	0.241	0.287	0	93.30269	3.780438	up_reg	67	0.0641162
CD38	P28907	2	2701	2	0.290	0.474	1	91.07150	2.603605	up_reg	9643	0.0631845
RYR1	P21817	2	1899	4	0.093	0.383	0	80.54768	3.086482	up_reg	7993	0.0621177
DSG2	Q14126	2	17165	3	0.361	0.262	0	65.83342	2.526737	up_reg	470	0.0611929
MELTF	P08582	2	0	1	0.273	0.298	0	89.73721	2.741729	up_reg	38	0.0607234
PRICKLE3	O43900	2	0	1	0.183	0.257	0	67.53085	2.181166	up_reg	13	0.0606762
EME1	Q96AY2	2	1520	2	0.155	0.315	0	67.90349	2.216719	up_reg	191	0.0606344
MFAP5	Q13361	12	0	1	-0.012	0.327	0	65.71101	3.343997	up_reg	81	0.0604613
MMP7	P09237	2	2130	3	0.296	0.381	0	87.58781	8.418438	up_reg	3046	0.0603333
MYCN	P04198	2	6049	4	0.286	0.329	0	61.81702	2.589804	up_reg	3302	0.0597757
ESCO2	Q56NI9	2	0	1	0.462	0.344	0	58.41527	4.684359	up_reg	136	0.0590688
TNFSF13B	Q9Y275	2	761	4	0.316	0.307	0	79.05813	2.662063	up_reg	1362	0.0585418
MUC16	Q8WXI7	2	1521	3	0.102	0.344	0	76.30687	8.476038	up_reg	1352	0.0577358
TFAP2C	Q92754	2	2279	3	0.181	0.278	0	66.88803	5.774422	up_reg	281	0.0573072
FAM181A	Q8N9Y4	2	0	1	0.330	0.241	0	60.50458	8.294660	up_reg	11	0.0567367
CCL20	P78556	2	2052	2	0.403	0.405	1	89.38489	5.283080	up_reg	2596	0.0557205
DDAH1	O94760	2	0	1	0.378	0.370	0	95.89648	2.198679	up_reg	338	0.0550072
FOXP3	Q9BZS1	2	761	2	0.090	0.491	1	58.06645	2.948779	up_reg	21309	0.0549219
DNAH5	Q8TE73	24	0	1	0.497	0.345	0	84.07641	3.828651	up_reg	183	0.0547608
CLDN7	O95471	2	1242	6	0.254	0.152	0	82.24946	6.596419	up_reg	302	0.0544738
LRP2	P98164	2	761	2	0.423	0.334	0	79.91038	4.927297	up_reg	452	0.0535911
SDC1	P18827	2	4415	6	0.400	0.203	0	55.99303	4.335717	up_reg	1549	0.0527575
GRB7	Q14451	2	0	1	0.214	0.360	0	78.88878	6.167946	up_reg	309	0.0524346
LAMA5	O15230	2	3467	4	0.149	0.195	0	79.60429	2.244719	up_reg	154	0.0518009
KCNK15	Q9H427	36	0	1	0.042	0.249	0	79.75423	5.076910	up_reg	19	0.0517830
FBN3	Q75N90	12	0	1	0.095	0.287	0	73.76318	5.054065	up_reg	53	0.0511291
OVGP1	Q12889	2	0	2	0.067	0.271	0	70.75963	2.519934	up_reg	105	0.0506303
POU5F1	Q01860	2	14481	8	0.257	0.119	0	66.34535	3.740793	up_reg	3858	0.0504231
E2F7	Q96AV8	2	1521	3	0.108	0.254	0	51.27249	4.380384	up_reg	224	0.0503707
H2AX	P16104	2	8754	10	0.328	0.078	0	87.32992	2.528322	up_reg	7218	0.0502524
CDCA4	Q9BXL8	2	2277	2	0.090	0.228	0	63.80400	2.599588	up_reg	44	0.0499316
MUC5B	Q9HC84	2	1020	3	0.121	0.321	0	61.04555	5.737039	up_reg	1207	0.0497234
ST6GALNAC5	Q9BVH7	3	0	1	0.187	0.268	0	82.09840	2.808701	up_reg	36	0.0495636
HLA-DQB1	P01920	2	13782	6	0.257	0.200	0	87.11210	4.148044	up_reg	3668	0.0494282
COL26A1	Q96A83	1	8	5	0.004	0.044	0	60.65501	3.863487	up_reg	8	0.0492052
JCHAIN	P01591	35	0	1	0.320	0.338	0	87.07085	3.236821	up_reg	219	0.0491086
TNFAIP6	P98066	2	1198	2	0.207	0.328	0	82.64910	2.971830	up_reg	536	0.0490182
SEMA3A	Q14563	2	3032	2	0.234	0.363	0	84.47667	3.102679	up_reg	1503	0.0488554
PIF1	Q9H611	2	0	1	0.062	0.368	0	77.97936	2.843531	up_reg	476	0.0487560
CENPF	P49454	2	10672	3	0.328	0.243	0	70.33298	4.302935	up_reg	385	0.0487119
SH2D2A	Q9NP31	2	761	2	0.085	0.258	0	62.79150	2.625689	up_reg	92	0.0484631
SYNGR2	O43760	50	0	1	0.192	0.229	0	81.66832	2.408663	up_reg	14	0.0483749
PI3	P19957	2	58	2	0.417	0.443	1	71.76906	7.675165	up_reg	9625	0.0475344
KCNQ1	P51787	2	1520	2	0.165	0.385	0	68.84458	2.709769	up_reg	2537	0.0474271
SEMA3F	Q13275	2	0	1	0.253	0.342	0	84.11920	3.717983	up_reg	283	0.0466328
STXBP6	Q8NFX7	52	0	1	0.123	0.254	0	87.12139	2.430172	up_reg	31	0.0462810
RTN4R	Q9BZR6	2	761	2	0.240	0.303	0	77.06296	2.676907	up_reg	339	0.0457712
KRT7	P08729	2	0	4	0.442	0.249	0	75.69421	7.336874	up_reg	692	0.0451941
RSPO1	Q2MKA7	37	8	4	0.111	0.221	0	75.36365	3.025055	up_reg	350	0.0448619
C4orf48	Q5BLP8	14	0	1	0.365	0.167	0	78.23739	4.028170	up_reg	3	0.0446724
SELPLG	Q14242	2	0	1	0.376	0.279	0	51.08547	2.634270	up_reg	66	0.0444860
TNFRSF8	P28908	2	526	2	0.196	0.238	0	61.29206	2.047671	up_reg	72	0.0440364
FAM167A	Q96KS9	29	0	1	0.247	0.255	0	72.66449	4.356541	up_reg	37	0.0439380
RYR1	P21817	2	1899	4	0.093	0.337	0	82.13187	3.086482	up_reg	7993	0.0437177
ESPN	B1AK53	2	3036	5	0.114	0.144	0	68.30997	7.443990	up_reg	202	0.0432265
CDH2	P19022	2	2326	5	0.099	0.215	0	79.17653	2.559787	up_reg	1215	0.0421722
MUC16	Q8WXI7	2	1521	3	0.065	0.305	0	75.39936	8.476038	up_reg	1352	0.0421358
RRM2	P31350	2	0	1	0.276	0.377	0	80.12601	5.527053	up_reg	906	0.0420986
BCL2A1	Q16548	2	0	1	0.333	0.327	0	87.41244	2.485455	up_reg	273	0.0412050
LRP2	P98164	2	761	2	0.155	0.303	0	79.58308	4.927297	up_reg	452	0.0411911
FCGR2B	P31994	2	0	1	0.421	0.355	0	79.03060	2.783225	up_reg	591	0.0401084
KRT14	P02533	2	0	4	0.398	0.236	0	75.92890	3.310309	up_reg	716	0.0394507
REC8	O95072	2	0	2	0.349	0.297	0	64.69331	3.247582	up_reg	418	0.0390920
VGLL1	Q99990	2	0	1	0.305	0.237	0	58.22350	10.261579	up_reg	32	0.0389898
CCL2	P13500	2	6612	3	0.274	0.389	0	87.56294	2.248695	up_reg	20922	0.0383422
FTH1	P02794	2	0	1	0.354	0.347	0	95.76727	2.083195	up_reg	545	0.0381995
CTSS	P25774	2	0	1	0.287	0.348	0	94.54174	2.821640	up_reg	564	0.0380535
TNNT1	P13805	2	0	2	0.147	0.251	0	74.97393	6.310523	up_reg	141	0.0379633
CCL28	Q9NRJ3	2	7221	4	0.193	0.182	0	73.22394	3.991313	up_reg	357	0.0378979
BEND3	Q5T5X7	2	0	1	0.249	0.292	0	65.37982	2.733342	up_reg	142	0.0375846
ITGA4	P13612	2	7750	3	0.145	0.211	0	84.56353	2.107446	up_reg	277	0.0375246
TP73	O15350	2	892	3	0.199	0.300	0	66.41421	3.196305	up_reg	1569	0.0369809
GREM1	O60565	12	0	1	0.032	0.346	0	73.24474	2.646893	up_reg	586	0.0366438
FBN2	P35556	12	7	3	0.059	0.237	0	72.51160	2.521524	up_reg	313	0.0363720
MUC5B	Q9HC84	2	1020	3	0.107	0.287	0	72.66008	5.737039	up_reg	1207	0.0361234
IL1B	P01584	2	9795	5	0.104	0.259	0	75.92467	2.915989	up_reg	9812	0.0357108
CDC20	Q12834	2	13778	4	0.319	0.217	0	84.85435	6.475074	up_reg	1650	0.0356360
MPPED2	Q15777	2	0	1	0.120	0.222	0	95.36715	4.417398	up_reg	28	0.0350523
RYR1	P21817	2	1899	4	0.089	0.315	0	81.69913	3.086482	up_reg	7993	0.0349177
EIF4EBP1	Q13541	2	0	1	0.320	0.379	0	71.29362	2.070414	up_reg	1560	0.0342324
COBL	O75128	2	0	1	0.050	0.270	0	50.28154	2.051585	up_reg	103	0.0338677
NRTN	Q99748	2	1521	3	0.352	0.216	0	79.04346	5.712851	up_reg	249	0.0334890
KRT19	P08727	2	1083	4	0.374	0.199	0	81.40007	3.098124	up_reg	448	0.0334656
PPL	O60437	2	7508	3	0.357	0.276	0	75.60075	2.018881	up_reg	2003	0.0316955
CD300A	Q9UGN4	2	0	1	0.291	0.270	0	70.96770	2.052455	up_reg	124	0.0309319
FBN3	Q75N90	12	0	1	0.244	0.236	0	75.06822	5.054065	up_reg	53	0.0307291
AIMP2	Q13155	4	0	1	0.116	0.258	0	81.79153	2.483720	up_reg	94	0.0305124
KCNQ3	O43525	2	0	2	0.045	0.284	0	57.10836	3.162918	up_reg	527	0.0302013
ULBP3	Q9BZM4	2	0	1	0.341	0.273	0	82.87018	4.365563	up_reg	143	0.0298734
CABLES1	Q8TDN4	2	0	1	0.107	0.239	0	57.81542	2.363657	up_reg	61	0.0297239
EPPK1	P58107	2	0	1	0.118	0.219	0	79.61520	6.941326	up_reg	38	0.0291234
KRT16	P08779	2	2509	5	0.333	0.106	0	74.43273	4.141592	up_reg	182	0.0290281
HLA-DPB1	P04440	2	0	4	0.168	0.229	0	87.13757	3.113183	up_reg	1195	0.0284837
LRFN1	Q9P244	2	1520	3	0.146	0.082	0	70.58550	3.127358	up_reg	11	0.0283563
PSMB9	P28065	2	0	1	0.362	0.276	0	91.17994	2.788039	up_reg	173	0.0280527
NACC1	Q96RE7	2	0	1	0.205	0.255	0	64.21521	3.382755	up_reg	102	0.0280219
TES	Q9UGI8	2	0	1	0.196	0.431	1	86.49349	2.394874	up_reg	8760	0.0274987
LILRB4	Q8NHJ6	2	0	2	0.423	0.240	0	66.70081	3.936863	up_reg	208	0.0273940
LRP2	P98164	2	761	2	0.148	0.268	0	74.88229	4.927297	up_reg	452	0.0271911
TACSTD2	P09758	2	0	1	0.332	0.294	0	82.22030	6.975909	up_reg	296	0.0267184
SIX1	Q15475	28	2	2	0.184	0.287	0	74.01302	5.368302	up_reg	721	0.0264089
PARS2	Q7L3T8	2	0	1	0.407	0.194	0	88.46743	2.174840	up_reg	24	0.0262213
TUBB4A	P04350	2	2031	4	0.190	0.124	0	92.24309	3.282229	up_reg	118	0.0258375
LRP2	P98164	2	761	2	0.249	0.264	0	84.11100	4.927297	up_reg	452	0.0255911
WWC1	Q8IX03	2	3714	3	0.055	0.175	0	61.50142	5.147188	up_reg	174	0.0255036
CHAC2	Q8WUX2	17	0	1	0.084	0.176	0	93.52453	2.630675	up_reg	16	0.0251771
SH2B2	O14492	2	0	2	0.200	0.184	0	64.23783	2.606184	up_reg	59	0.0249140
CCNB2	O95067	2	21505	5	0.089	0.073	0	80.38333	4.940087	up_reg	453	0.0248989
CDT1	Q9H211	2	761	3	0.393	0.234	0	74.90779	4.825580	up_reg	656	0.0243233
BANK1	Q8NDB2	2	0	1	0.100	0.248	0	61.61418	3.730736	up_reg	117	0.0230518
ARL11	Q969Q4	2	0	1	0.147	0.203	0	88.13514	3.125100	up_reg	38	0.0227234
S100A9	P06702	2	2897	5	0.328	0.187	0	94.90595	2.289678	up_reg	2190	0.0222827
NHERF1	O14745	2	1521	3	0.202	0.212	0	72.47472	3.097348	up_reg	466	0.0219151
POMK	Q9H5K3	2	761	2	0.236	0.139	0	91.65736	5.585370	up_reg	24	0.0218323
CXCL9	Q07325	2	4000	3	0.304	0.283	0	87.92398	5.250589	up_reg	3397	0.0217137
S100A2	P29034	2	0	1	0.329	0.282	0	87.05777	5.595045	up_reg	304	0.0214941
WNT11	O96014	2	0	1	0.355	0.304	0	90.30817	2.266810	up_reg	623	0.0188681
PPP1R1B	Q9UD71	2	0	1	0.401	0.285	0	66.04138	2.849180	up_reg	390	0.0187293
DSP	P15924	2	2832	2	0.165	0.337	0	77.42383	4.716943	up_reg	5445	0.0176685
HOXB4	P17483	2	0	3	0.094	0.202	0	68.07405	4.785876	up_reg	429	0.0173451
PCBD1	P61457	2	0	1	0.378	0.180	0	96.56937	2.014142	up_reg	30	0.0171877
GALNT5	Q7Z7M9	2	0	1	0.076	0.151	0	69.18376	3.327325	up_reg	15	0.0161448
UQCRFS1	P47985	2	0	1	0.381	0.202	0	81.75593	2.088377	up_reg	57	0.0159885
MYCL	P12524	11	0	1	0.386	0.235	0	65.02508	7.726211	up_reg	137	0.0153527
TNFAIP2	Q03169	52	0	1	0.238	0.221	0	85.94862	2.993107	up_reg	97	0.0152162
PLK4	O00444	2	767	3	0.133	0.199	0	66.92294	2.644551	up_reg	485	0.0151428
ISG15	P05161	2	10014	6	0.503	0.095	0	86.54014	4.583876	up_reg	1808	0.0140394
COX6B1	P14854	2	13	2	0.393	0.135	0	94.90168	2.489263	up_reg	35	0.0134838
DOK5	Q9P104	2	0	1	0.200	0.179	0	78.36019	5.673957	up_reg	38	0.0131234
EXOSC4	Q9NPD3	2	0	1	0.335	0.159	0	89.83185	2.636612	up_reg	25	0.0115953
MATK	P42679	2	3136	3	0.135	0.225	0	83.78212	2.482567	up_reg	1410	0.0114700
MUC5B	Q9HC84	2	1020	3	0.071	0.225	0	65.92865	5.737039	up_reg	1207	0.0113234
RYR1	P21817	2	1899	4	0.187	0.254	0	79.11971	3.086482	up_reg	7993	0.0105177
SPI1	P17947	2	0	2	0.383	0.269	0	65.99688	2.766086	up_reg	1314	0.0096363
NDUFB3	O43676	2	0	1	0.294	0.157	0	86.46141	2.013948	up_reg	28	0.0090523
TNFRSF21	O75509	2	2279	3	0.215	0.137	0	69.40738	2.418514	up_reg	172	0.0087063
SALL4	Q9UJQ4	2	0	1	0.204	0.290	0	51.44781	3.878009	up_reg	846	0.0083910
FBN3	Q75N90	12	0	1	0.157	0.180	0	75.79856	5.054065	up_reg	53	0.0083291
MUC16	Q8WXI7	2	1521	3	0.085	0.220	0	75.54095	8.476038	up_reg	1352	0.0081358
MAP7	Q14244	2	0	1	0.366	0.202	0	62.54288	3.092922	up_reg	94	0.0081124
LRP8	Q14114	2	1520	2	0.423	0.171	0	73.62178	2.246711	up_reg	139	0.0080760
EYA4	O95677	28	0	1	0.371	0.218	0	64.03401	3.012436	up_reg	144	0.0077629
IFIT3	O14879	2	5526	3	0.158	0.152	0	75.74696	2.375046	up_reg	344	0.0077182
COL9A2	Q14055	1	0	3	0.053	0.140	0	55.63427	4.196349	up_reg	167	0.0075462
HDGF	P51858	26	0	1	0.359	0.250	0	68.36683	2.071828	up_reg	328	0.0074851
CLEC5A	Q9NY25	2	348	2	0.252	0.165	0	85.45138	2.904175	up_reg	115	0.0072232
LSP1	P33241	2	563	2	0.145	0.204	0	60.56910	2.311015	up_reg	316	0.0070435
NTN1	O95631	2	761	2	0.246	0.236	0	88.71749	3.118007	up_reg	738	0.0065793
RIPK3	Q9Y572	2	0	1	0.217	0.318	0	67.61724	2.151159	up_reg	1999	0.0058767
PDZK1IP1	Q13113	2	761	2	0.247	0.145	0	65.20753	7.379819	up_reg	81	0.0052724
ARL4C	P56559	2	0	1	0.393	0.180	0	93.52089	4.733473	up_reg	65	0.0051260
MUC5B	Q9HC84	2	1020	3	0.067	0.207	0	75.11554	5.737039	up_reg	1207	0.0041234
TMEM30B	Q3MIR4	9	0	1	0.223	0.113	0	92.35448	3.021734	up_reg	13	0.0030762
MSLN	Q13421	2	0	1	0.171	0.275	0	79.08734	7.267283	up_reg	812	0.0030450
SKA1	Q96BD8	2	3740	3	0.218	0.102	0	85.82242	5.476597	up_reg	114	0.0030375
LRP2	P98164	2	761	2	0.160	0.207	0	84.41689	4.927297	up_reg	452	0.0027911
PMAIP1	Q13794	2	3032	2	0.317	0.217	0	82.91014	3.896961	up_reg	738	0.0017976
ITGB7	P26010	2	2752	2	0.268	0.121	0	82.84386	3.324527	up_reg	73	-0.0002183
SYTL1	Q8IYJ3	2	3037	4	0.036	0.011	0	72.77781	4.342698	up_reg	40	-0.0011060
KSR2	Q6VAB6	2	0	1	0.284	0.169	0	61.41177	5.960690	up_reg	79	-0.0023446
CKS2	P33552	2	0	1	0.368	0.194	0	92.87122	4.440040	up_reg	168	-0.0042819
FAAP24	Q9BTP7	2	761	2	0.199	0.087	0	90.18733	2.416477	up_reg	35	-0.0047880
SH3RF2	Q8TEC5	2	0	1	0.059	0.105	0	57.59249	2.729593	up_reg	18	-0.0049982
DSP	P15924	2	2832	2	0.201	0.279	0	80.86139	4.716943	up_reg	5445	-0.0055315
EPPK1	P58107	2	0	1	0.162	0.131	0	79.60039	6.941326	up_reg	38	-0.0060766
COX5B	P10606	2	41	3	0.105	0.096	0	85.69271	2.427432	up_reg	136	-0.0067470
MUC4	Q99102	2	0	1	0.254	0.266	0	58.53420	3.542323	up_reg	1209	-0.0069021
PCLAF	Q15004	2	0	1	0.264	0.167	0	66.12640	5.401491	up_reg	103	-0.0073323
SPINT1	O43278	51	0	1	0.107	0.200	0	77.01837	6.141109	up_reg	238	-0.0074136
TRIB1	Q96RU8	2	0	1	0.268	0.201	0	77.94675	2.875736	up_reg	271	-0.0090781
CD48	P09326	2	761	2	0.445	0.219	0	83.72723	3.054479	up_reg	1312	-0.0093950
CXCL11	O14625	2	1773	3	0.353	0.178	0	77.92419	7.143297	up_reg	1585	-0.0108876
IL18	Q14116	2	2672	3	0.438	0.267	0	89.07080	3.642493	up_reg	16116	-0.0111817
CLIC3	O95833	20	0	1	0.143	0.127	0	94.15899	4.900396	up_reg	48	-0.0113200
LTB	Q06643	2	1331	3	0.279	0.194	0	78.39808	5.296640	up_reg	2405	-0.0116882
LILRB1	Q8NHL6	2	1319	3	0.177	0.118	0	73.03943	2.334817	up_reg	396	-0.0133436
LRP2	P98164	2	761	2	0.183	0.166	0	76.02884	4.927297	up_reg	452	-0.0136089
CLU	P10909	2	1521	5	0.158	0.104	0	76.87086	2.491979	up_reg	2364	-0.0138447
BID	P55957	2	0	1	0.136	0.357	0	62.45273	2.048675	up_reg	19500	-0.0148731
PPP2R2B	Q00005	2	3032	3	0.106	0.055	0	90.41175	3.664496	up_reg	113	-0.0165017
LRP2	P98164	2	761	2	0.221	0.158	0	82.10400	4.927297	up_reg	452	-0.0168089
COL22A1	Q8NFW1	1	0	3	0.106	0.037	0	54.74523	2.383929	up_reg	58	-0.0169511
APLP1	P51693	2	0	1	0.120	0.183	0	69.72252	4.237735	up_reg	286	-0.0171349
RIPK4	P57078	2	15	2	0.135	0.096	0	74.60517	6.184659	up_reg	100	-0.0185799
GRN	P28799	2	761	2	0.140	0.230	0	76.98417	2.143488	up_reg	3094	-0.0186817
DNAH5	Q8TE73	24	0	1	0.245	0.161	0	81.81473	3.828651	up_reg	183	-0.0188392
ILDR2	Q71H61	2	0	1	0.046	0.075	0	56.53694	2.554303	up_reg	23	-0.0207271
RGCC	Q9H4X1	2	0	1	0.314	0.141	0	71.58154	2.366748	up_reg	128	-0.0211708
MUC16	Q8WXI7	2	1521	3	0.095	0.146	0	75.51818	8.476038	up_reg	1352	-0.0214642
SOX17	Q9H6I2	2	6	2	0.278	0.181	0	59.27884	4.879374	up_reg	1021	-0.0215327
JUP	P14923	2	14648	4	0.091	0.021	0	81.10563	2.578337	up_reg	484	-0.0221315
HMGA1	P17096	2	1520	2	0.159	0.181	0	65.46237	6.591907	up_reg	1299	-0.0234943
CD4	P01730	2	3035	4	0.442	0.289	0	85.57181	2.281950	up_reg	186553	-0.0243523
C15orf48	Q9C002	2	0	2	0.212	0.018	0	89.84824	5.134800	up_reg	21	-0.0254716
DNMT3B	Q9UBC3	2	56	2	0.077	0.203	0	73.57543	2.148336	up_reg	2407	-0.0263504
CCL8	P80075	2	0	2	0.258	0.153	0	89.58629	3.845029	up_reg	703	-0.0267906
KLK8	O60259	2	0	1	0.329	0.140	0	88.53643	7.914436	up_reg	184	-0.0273257
LCN2	P80188	2	0	1	0.140	0.259	0	91.99169	9.042459	up_reg	3659	-0.0273692
ESRP2	Q9H6T0	2	0	1	0.052	0.103	0	74.32537	4.950124	up_reg	77	-0.0283405
MUC5B	Q9HC84	2	1020	3	0.184	0.124	0	56.96292	5.737039	up_reg	1207	-0.0290766
EPCAM	P16422	2	77	2	0.289	0.252	0	87.50649	7.738423	up_reg	9825	-0.0291702
EPS8L1	Q8TE68	2	0	1	0.064	0.026	0	75.61647	5.101489	up_reg	11	-0.0292633
CHI3L1	P36222	2	761	3	0.134	0.135	0	94.99146	4.967392	up_reg	1596	-0.0294538
FEN1	P39748	2	0	3	0.078	0.113	0	90.03506	2.230667	up_reg	874	-0.0295948
HP	P00738	2	0	1	0.249	0.384	0	86.65695	3.617985	up_reg	99196	-0.0300371
COL10A1	Q03692	1	5	4	-0.010	0.058	0	61.49775	4.041689	up_reg	679	-0.0308974
RAB25	P57735	41	0	1	0.148	0.130	0	87.08353	7.156164	up_reg	189	-0.0317514
FOXQ1	Q9C009	2	0	1	0.151	0.132	0	62.11694	8.570065	up_reg	207	-0.0323961
HOXB7	P09629	2	761	4	-0.001	0.021	0	66.86952	5.290210	up_reg	318	-0.0326778
CHMP4C	Q96CF2	2	0	1	0.263	0.083	0	77.35806	4.735938	up_reg	64	-0.0334303
CARD11	Q9BXL7	2	761	2	0.121	0.124	0	72.04895	2.481919	up_reg	557	-0.0337364
LRP2	P98164	2	761	2	0.108	0.115	0	82.21634	4.927297	up_reg	452	-0.0340089
ILDR1	Q86SU0	2	0	1	0.115	0.071	0	58.96387	8.292796	up_reg	49	-0.0340425
MUC5B	Q9HC84	2	1020	3	0.166	0.110	0	54.61585	5.737039	up_reg	1207	-0.0346766
CDCA7	Q9BWT1	2	0	1	0.158	0.087	0	66.71299	3.825804	up_reg	85	-0.0362989
TGM1	P22735	2	1487	3	0.097	0.042	0	85.13601	2.974339	up_reg	253	-0.0364066
CXCL10	P02778	2	0	2	0.109	0.230	0	90.08511	6.235378	up_reg	8876	-0.0364446
EPPK1	P58107	2	0	1	0.207	0.048	0	78.87880	6.941326	up_reg	38	-0.0392766
CSF2RA	P15509	2	0	1	0.110	0.079	0	82.07854	2.326266	up_reg	117	-0.0445482
RAP1GAP	P47736	2	2277	2	0.060	0.047	0	70.99696	3.713069	up_reg	184	-0.0450333
DUSP23	Q9BVJ7	2	0	1	0.465	0.001	0	97.64673	2.213370	up_reg	17	-0.0457352
PITX1	P78337	2	0	1	0.326	0.132	0	63.26645	4.758002	up_reg	479	-0.0457441
ESM1	Q9NQ30	2	0	1	0.181	0.124	0	73.14345	3.038808	up_reg	509	-0.0499118
IL1RN	P18510	2	0	1	0.197	0.201	0	87.13193	4.132662	up_reg	3592	-0.0502743
SKAP1	Q86WV1	2	0	1	0.224	0.046	0	71.43923	5.275064	up_reg	75	-0.0507258
NMU	P48645	2	0	1	0.141	0.161	0	63.72954	8.371797	up_reg	1511	-0.0524586
NKD2	Q969F2	2	0	1	0.151	0.047	0	56.92392	2.149191	up_reg	86	-0.0524835
TNF	P01375	2	6688	6	0.273	0.119	0	85.00767	6.265458	up_reg	221351	-0.0572156
MAD2L1	Q13257	2	3785	3	0.178	0.019	0	93.75853	3.426759	up_reg	681	-0.0585201
LRP2	P98164	2	761	2	0.183	0.052	0	82.08045	4.927297	up_reg	452	-0.0592089
CCNF	P41002	2	0	1	0.276	0.059	0	72.44700	2.582579	up_reg	183	-0.0596392
RYR1	P21817	2	1899	4	0.098	0.071	0	85.54549	3.086482	up_reg	7993	-0.0626823
LRP2	P98164	2	761	2	0.123	0.038	0	71.99966	4.927297	up_reg	452	-0.0648089
CARD9	Q9H257	2	0	1	0.125	0.087	0	81.15426	3.240362	up_reg	539	-0.0656241
HMGA2	P52926	2	761	2	0.202	0.089	0	65.13682	5.165815	up_reg	1858	-0.0669453
LYZ	P61626	2	0	1	0.190	0.093	0	94.45464	3.176699	up_reg	688	-0.0671135
SGO1	Q5FBB7	2	0	1	0.108	0.050	0	55.17324	5.338592	up_reg	255	-0.0685104
CDKN2B	P42772	2	0	1	0.321	0.128	0	90.76140	2.453778	up_reg	2033	-0.0703923
MUC16	Q8WXI7	2	1521	3	0.186	0.021	0	67.43678	8.476038	up_reg	1352	-0.0714642
E2F2	Q14209	2	0	1	0.180	0.079	0	64.08260	5.446447	up_reg	639	-0.0715360
BORA	Q6PGQ7	2	0	1	0.259	0.158	0	50.73243	2.025953	up_reg	4796	-0.0720873
DYRK1B	Q9Y463	25	0	1	0.097	0.022	0	74.53225	2.195558	up_reg	164	-0.0726995
MET	P08581	2	3305	3	0.093	0.209	0	79.58763	2.695561	up_reg	276508	-0.0789652
SPP1	P10451	2	2257	2	0.312	0.072	0	53.13979	5.389308	up_reg	4958	-0.0875498
GDF15	Q99988	2	0	1	0.062	0.082	0	75.41460	2.195446	up_reg	2514	-0.0921805

Show unique genes only

kable(pcsf_master_edit_unique, format = "html", caption = "Ordered by Combined Rank Score") %>%
kable_styling(full_width = FALSE) %>%
scroll_box(height = "400px")

Ordered by Combined Rank Score

	external_gene_name	uniprot_gn_id	cluster	betweenness	degree_centrality	pocket	druggability	num_drug_pockets	struct_score	logFC	regulation	citation_score	combined_score
38	H2BC4	P62807	2	38282	12	0.291	0.965	1	87.82973	2.638893	up_reg	0	0.6168408
79	H2BC12	O60814	2	24896	11	0.241	0.937	1	88.05779	3.203629	up_reg	2	0.5548266
73	H2BC9	Q93079	2	24695	11	0.364	0.940	2	88.14311	4.450921	up_reg	3	0.5511852
52	PLK1	P53350	2	53880	14	0.175	0.953	2	85.16989	3.894749	up_reg	2971	0.5370856
263	LYN	P07948	2	49848	19	0.072	0.759	1	83.72670	2.498330	up_reg	3594	0.5347776
128	KIF9	Q9HAQ2	2	7104	13	0.202	0.885	1	75.21325	2.195679	up_reg	31	0.5074970
81	RAC3	P60763	2	18877	11	0.341	0.937	1	93.83371	2.514936	up_reg	299	0.4738508
146	H2BC11	P06899	2	72	9	0.250	0.870	2	85.69804	3.968938	up_reg	1	0.4703589
317	CCNB1	P14635	2	76783	14	0.078	0.699	1	77.77241	3.784353	up_reg	2285	0.4680967
201	KIF20A	O95235	2	24557	13	0.333	0.814	3	67.30456	5.657319	up_reg	301	0.4649268
129	CD3E	P07766	2	14667	11	0.191	0.884	1	73.51280	2.881956	up_reg	540	0.4380146
609	LCK	P06239	2	54987	19	0.188	0.471	1	84.33331	2.329222	up_reg	3794	0.4250908
19	KIF11	P52732	2	1046	9	0.141	0.991	1	74.76864	4.407716	up_reg	820	0.4239201
140	GRIK3	Q13003	2	17866	8	0.152	0.878	1	82.38048	3.473939	up_reg	66	0.4229241
28	SYK	P43405	2	13379	10	0.203	0.979	2	84.33036	4.407191	up_reg	5393	0.4210437
20	KLC3	Q6P597	11	3	3	0.212	0.991	1	76.01520	4.822387	up_reg	19	0.3819201
512	UBE2S	Q16763	2	77901	9	0.168	0.552	1	81.85029	2.769728	up_reg	116	0.3747951
112	ATP5MC1	P05496	2	3791	3	0.401	0.898	1	72.69576	2.063501	up_reg	4	0.3715486
113	TOP2A	P11388	2	22036	7	0.045	0.897	1	76.40832	5.212828	up_reg	1327	0.3713590
148	KIF15	Q9NS87	2	2175	7	0.241	0.869	1	72.02130	3.950703	up_reg	155	0.3696949
89	APOA1	P02647	2	9356	8	0.278	0.929	3	73.61168	3.065972	up_reg	3491	0.3696582
77	RAC2	P15153	2	1171	7	0.227	0.939	1	93.54571	2.156389	up_reg	917	0.3681594
12	CENPU	Q71F23	2	0	3	0.002	0.994	1	65.51860	3.558826	up_reg	59	0.3655807
16	PLPP4	Q5VZY2	45	0	1	0.383	0.993	2	92.00338	5.658002	up_reg	11	0.3575367
44	TGFA	P01135	2	3905	5	0.202	0.961	1	66.88685	4.466767	up_reg	481	0.3573023
42	NAXE	Q8NCW5	2	1521	3	0.423	0.962	1	86.87614	2.208627	up_reg	51	0.3569523
6	CENPE	Q02224	2	1501	4	0.135	0.997	5	72.55249	2.847355	up_reg	436	0.3536167
133	PKP3	Q9Y446	2	31976	3	0.070	0.881	1	69.28451	7.141531	up_reg	91	0.3532397
85	PPP4C	P60510	2	1521	3	0.387	0.933	1	94.87746	2.136177	up_reg	32	0.3526107
8	BNIPL	Q7Z465	2	0	1	0.190	0.996	1	68.65183	3.984513	up_reg	17	0.3522648
63	LAMA5	O15230	2	3467	4	0.086	0.946	2	79.24314	2.244719	up_reg	154	0.3522009
138	LRRC43	Q8N309	2	0	1	0.240	0.879	1	74.70035	2.069984	up_reg	0	0.3516000
3	CACNA1F	O60840	2	1139	3	0.170	0.999	5	67.32468	3.652392	up_reg	184	0.3510211
78	RIMKLA	Q8IXN7	2	0	1	0.297	0.938	1	81.13650	3.884952	up_reg	4	0.3495106
215	TPM3	P06753	2	8572	8	0.348	0.799	1	91.78888	2.201758	up_reg	485	0.3481620
10	FAAH2	Q6GMR7	23	0	1	0.082	0.995	1	94.18245	3.735525	up_reg	24	0.3466213
13	KCNK12	Q9HB15	36	0	1	0.139	0.994	1	73.78490	2.598125	up_reg	25	0.3455953
60	NDUFB9	Q9Y6M9	2	4536	2	-0.051	0.948	1	96.13232	2.289772	up_reg	33	0.3452091
69	MYO3B	Q8WXR4	2	0	2	0.144	0.942	1	75.66990	6.420588	up_reg	22	0.3434189
141	BAIAP2L1	Q9UHR4	2	3579	4	0.324	0.876	2	74.93578	4.062937	up_reg	46	0.3433866
58	ASPM	Q8IZT6	2	8922	4	0.434	0.949	4	62.64048	4.312243	up_reg	510	0.3411291
649	PPP1CA	P62136	2	17077	14	0.206	0.440	1	91.55269	2.763584	up_reg	98	0.3405131
309	FAM166B	A8MTA8	2	0	6	0.110	0.707	1	69.27333	3.014622	up_reg	4	0.3404440
115	ATP5MF	P56134	2	0	1	0.423	0.892	3	74.16835	2.318005	up_reg	2	0.3392643
221	BRCA2	P51587	2	32217	9	0.083	0.796	1	65.83808	2.245119	up_reg	14293	0.3389992
47	DNAH3	Q8TD57	24	0	1	0.164	0.960	4	85.66639	3.642484	up_reg	16	0.3387771
479	H4C9	P62805	2	13910	7	0.336	0.581	1	90.43752	4.248213	up_reg	1	0.3385983
137	TJP3	O95049	2	0	4	0.067	0.880	2	66.58409	6.724088	up_reg	60	0.3363835
107	AGR2	O95994	2	5272	5	0.263	0.901	1	87.41946	5.133482	up_reg	449	0.3360952
32	SLC35F2	Q8IXU6	2	0	1	-0.002	0.970	2	82.73241	2.149731	up_reg	26	0.3353929
24	TEAD4	Q15561	2	1521	3	0.243	0.986	2	76.58312	2.660133	up_reg	381	0.3347219
5	SULT1C2	O00338	53	0	1	0.298	0.998	1	95.75467	4.617490	up_reg	56	0.3346661
143	HLA-DOA	P06340	2	7	4	0.429	0.874	1	90.25303	3.324934	up_reg	61	0.3337326
244	HLA-DPA1	P20036	2	40869	5	0.282	0.776	1	90.64308	3.525234	up_reg	363	0.3336560
2	MAPK15	Q8TD08	20	0	1	0.055	1.000	1	69.39014	4.731041	up_reg	63	0.3336172
27	TNFAIP8L2	Q6P589	2	761	2	0.017	0.981	1	90.74994	2.015314	up_reg	130	0.3321947
29	FBN2	P35556	12	7	3	0.107	0.975	1	75.78393	2.521524	up_reg	313	0.3315720
70	TNFRSF12A	Q9NP84	2	1609	4	0.111	0.942	1	73.27291	3.640033	up_reg	446	0.3313896
23	NINJ2	Q9NZG7	2	0	1	0.185	0.987	3	67.54372	3.668185	up_reg	59	0.3294473
233	KRT86	O43790	2	13	5	0.408	0.788	4	75.55742	5.650357	up_reg	27	0.3286952
166	BUB1B	O60566	2	3360	6	0.211	0.846	2	64.72058	4.320179	up_reg	471	0.3276272
36	SGPP2	Q8IWX5	45	0	1	0.102	0.966	1	84.21180	5.853240	up_reg	40	0.3271251
222	VANGL1	Q8TAA9	2	4805	6	0.038	0.796	2	75.85692	2.706602	up_reg	163	0.3262938
181	MRPL47	Q9HD33	2	1164	3	0.233	0.830	1	84.37084	2.125313	up_reg	12	0.3258369
373	TUBB4B	P68371	2	4864	8	0.258	0.659	2	92.02804	2.059976	up_reg	44	0.3255420
401	CLDN10	P78369	2	8628	9	0.400	0.636	1	79.69633	6.283497	up_reg	99	0.3249343
55	TSPAN33	Q86UF1	2	0	1	0.034	0.951	2	89.66649	2.598895	up_reg	32	0.3245898
121	ZNF492	Q9P255	56	0	1	0.218	0.888	1	73.55861	2.697025	up_reg	6	0.3241400
1	IL4I1	Q96RQ9	10	0	1	0.511	1.000	1	86.82116	7.731687	up_reg	124	0.3229319
296	CNIH2	Q6PI25	2	19080	5	0.314	0.723	2	87.25387	2.690596	up_reg	37	0.3214827
9	SULT2B1	O00204	53	0	1	0.599	0.996	1	87.72190	4.651085	up_reg	124	0.3213319
158	MARVELD3	Q96A59	2	0	3	0.108	0.860	1	65.32157	3.677035	up_reg	36	0.3196970
199	CENPA	P49450	2	17610	6	0.140	0.815	2	82.07836	6.059723	up_reg	1089	0.3195521
33	LGR6	Q9HBX8	37	0	2	0.408	0.967	2	78.17419	3.761788	up_reg	191	0.3195481
65	RTN2	O75298	49	0	1	0.162	0.944	2	51.12613	2.365362	up_reg	37	0.3195380
49	FBN3	Q75N90	12	0	1	0.195	0.958	2	75.30388	5.054065	up_reg	53	0.3195291
41	SLC16A3	O15427	2	1520	2	0.025	0.963	1	83.58743	2.015156	up_reg	195	0.3195053
80	MPZL2	O60487	40	0	1	0.433	0.937	2	89.47771	3.309876	up_reg	35	0.3176010
478	H4C8	P62805	2	5828	7	0.336	0.581	1	90.43752	2.770586	up_reg	3	0.3175049
26	LY86	O95711	15	0	1	0.075	0.983	1	87.70983	3.088945	up_reg	119	0.3167835
293	CFAP45	Q9UL16	2	1552	5	0.131	0.728	3	74.80989	2.226990	up_reg	15	0.3155375
104	ATP10B	O94823	9	0	1	0.117	0.904	2	71.43291	5.180540	up_reg	18	0.3146018
103	CENPF	P49454	2	10672	3	0.122	0.906	1	71.41875	4.302935	up_reg	385	0.3139119
43	CYP4F3	Q08477	22	0	1	0.156	0.961	2	91.82752	4.018495	up_reg	84	0.3134878
421	RIBC2	Q9H4K1	2	2064	7	0.365	0.625	1	86.74874	3.939408	up_reg	11	0.3128981
142	TSPAN15	O95858	2	2277	2	0.296	0.875	2	87.94298	3.591096	up_reg	34	0.3127430
168	USP43	Q70EL4	2	470	2	0.025	0.846	2	61.36801	3.739775	up_reg	14	0.3124249
30	CACNA1B	Q00975	2	6	2	0.130	0.971	2	60.38413	4.783153	up_reg	334	0.3122707
34	LPAR5	Q9H1C0	2	0	1	0.250	0.967	1	83.69589	3.173233	up_reg	108	0.3119181
25	UNC93B1	Q9H1C4	54	0	1	0.082	0.986	1	80.17879	3.392612	up_reg	175	0.3118703
35	ALDH3A1	P30838	5	0	2	0.345	0.966	1	97.89977	3.119278	up_reg	316	0.3111448
375	MCM4	P33991	2	9512	9	0.217	0.658	3	73.74330	2.743419	up_reg	448	0.3108592
39	LAPTM5	Q13571	38	0	1	0.239	0.964	2	69.27503	2.290592	up_reg	113	0.3100023
710	AP1S3	Q96PC3	2	11076	13	0.308	0.385	0	93.25617	3.118487	up_reg	40	0.3084703
105	HCST	Q9UBK5	2	1076	3	0.330	0.904	2	67.31898	2.736939	up_reg	246	0.3083295
7	RYR1	P21817	2	1899	4	0.226	0.997	3	75.55434	3.086482	up_reg	7993	0.3077177
131	TUBA1C	Q9BQE3	2	861	2	0.219	0.883	1	91.65244	3.360826	up_reg	52	0.3075626
48	STC2	O76061	2	0	2	0.270	0.960	2	73.29585	3.187642	up_reg	353	0.3069827
11	CD9	P21926	2	1521	3	0.063	0.994	1	88.11915	3.619361	up_reg	2704	0.3066779
98	SDC4	P31431	2	4689	3	0.270	0.917	2	63.14462	2.128542	up_reg	556	0.3050335
122	KLHL14	Q9P2G3	6	0	1	0.483	0.887	1	88.14009	5.754363	up_reg	22	0.3047522
102	EPPK1	P58107	2	0	1	0.247	0.908	1	77.46931	6.941326	up_reg	38	0.3047234
275	CENPL	Q8N0S6	2	4202	4	0.229	0.746	2	83.65047	2.321809	up_reg	22	0.3035668
159	NRCAM	Q92823	2	1726	4	0.090	0.859	2	78.95628	2.470745	up_reg	323	0.3034715
45	ADGRG1	Q9Y653	2	0	1	0.294	0.960	2	78.01376	4.084734	up_reg	168	0.3021181
155	SVOPL	Q8N434	49	0	1	0.061	0.862	1	84.05384	3.101728	up_reg	14	0.3015749
312	PERP	Q96FX8	2	31898	6	0.129	0.705	1	82.35155	3.211249	up_reg	673	0.3009562
64	GPR37	O15354	2	0	1	0.097	0.945	5	61.81102	4.508915	up_reg	144	0.2985629
116	CTSC	P53634	2	0	3	0.338	0.892	2	90.37857	2.162863	up_reg	316	0.2982115
51	TTK	P33981	2	3035	3	0.087	0.956	1	63.95435	5.915254	up_reg	2047	0.2977979
94	CHST6	Q9GZX3	18	0	1	0.409	0.920	1	90.80083	5.468416	up_reg	84	0.2970878
260	ANLN	Q9NQW6	2	10469	5	0.121	0.760	1	59.87419	3.455958	up_reg	227	0.2969970
234	ACTR3C	Q9C0K3	2	0	1	0.040	0.786	1	88.11260	2.000050	up_reg	2	0.2968643
4	AQP9	O43315	2	0	1	0.470	0.998	1	91.06600	3.553111	up_reg	637	0.2961140
84	RSAD2	Q8WXG1	2	380	2	0.193	0.935	1	87.95684	2.536852	up_reg	393	0.2957456
163	ARFGEF3	Q5TH69	2	0	1	0.051	0.852	3	65.48151	3.121775	up_reg	16	0.2955771
224	B3GNT3	Q9Y2A9	2	3789	3	0.149	0.793	1	88.42372	7.460360	up_reg	42	0.2952003
97	NR2F6	P10588	2	0	1	0.399	0.917	1	79.75002	3.297460	up_reg	89	0.2949754
14	MELK	Q14680	2	0	1	0.159	0.993	1	70.64372	5.528457	up_reg	659	0.2935729
54	ERBB4	Q15303	2	3810	3	0.069	0.951	1	73.09162	5.365254	up_reg	2501	0.2935637
88	MUC5B	Q9HC84	2	1020	3	0.112	0.930	1	82.35068	5.737039	up_reg	1207	0.2933234
62	TDO2	P48775	34	0	1	0.175	0.947	1	90.52437	5.860687	up_reg	223	0.2924210
230	AURKB	Q96GD4	2	7020	6	0.060	0.789	2	79.85404	5.582702	up_reg	1367	0.2923840
151	DIAPH3	Q9NSV4	2	322	2	0.164	0.866	2	71.81813	4.609425	up_reg	86	0.2921828
61	AIFM1	O95831	2	39	2	0.136	0.947	1	85.79458	2.212459	up_reg	647	0.2921808
93	CDC6	Q99741	2	761	3	0.244	0.922	2	69.83948	3.142206	up_reg	1059	0.2918882
82	DNAH5	Q8TE73	24	0	1	0.234	0.936	1	81.69210	3.828651	up_reg	183	0.2911608
17	XDH	P47989	46	0	1	0.138	0.993	3	96.09594	7.452060	up_reg	800	0.2904823
147	KREMEN2	Q8NCW0	37	0	1	0.459	0.870	1	76.82793	7.640887	up_reg	36	0.2903636
172	CCNO	P22674	2	761	3	0.405	0.838	2	79.73102	2.663074	up_reg	142	0.2902623
22	CYP2J2	P51589	22	0	1	0.080	0.987	1	93.78906	4.606358	up_reg	707	0.2900523
179	CX3CR1	P49238	2	1960	6	0.114	0.832	2	80.21817	4.725471	up_reg	3143	0.2900221
50	CYBA	P13498	2	0	2	0.480	0.957	1	77.02989	3.871486	up_reg	1043	0.2885199
124	ANPEP	P15144	2	761	2	0.232	0.886	1	93.75126	3.535249	up_reg	188	0.2883439
237	TIMELESS	Q9UNS1	2	2280	6	0.482	0.784	2	75.06448	2.414253	up_reg	1146	0.2873142
68	IFI27	P40305	2	0	1	0.066	0.942	1	52.14211	4.811702	up_reg	273	0.2872050
213	LRRC46	Q96FV0	2	0	1	0.095	0.800	1	64.78600	2.513569	up_reg	7	0.2868086
370	COX5A	P20674	2	14138	6	0.376	0.660	1	88.10962	2.578447	up_reg	134	0.2865819
91	CDC45	O75419	2	884	2	0.323	0.926	1	92.88743	4.831525	up_reg	594	0.2861914
303	ATP6V0E2	Q8NHE4	2	1521	3	0.416	0.712	1	94.37485	2.427263	up_reg	8	0.2849494
422	RMI2	Q96E14	2	2582	7	0.286	0.624	1	89.81185	2.702399	up_reg	75	0.2836784
271	MSR1	P21757	2	2506	6	0.363	0.749	1	71.98684	2.514585	up_reg	611	0.2836213
15	NOX4	Q9NPH5	2	322	2	0.046	0.993	3	86.75705	2.565399	up_reg	3755	0.2828838
239	FCER1G	P30273	2	1521	4	0.480	0.783	1	72.33766	3.253477	up_reg	173	0.2827403
167	GRIN2D	O15399	2	0	2	0.143	0.846	3	64.00209	3.116091	up_reg	93	0.2825480
424	H3C8	P68431	2	11	3	0.351	0.623	1	87.28692	7.878421	up_reg	0	0.2825470
423	H3C10	P68431	2	0	3	0.351	0.623	1	87.28692	2.688200	up_reg	0	0.2825333
255	PLEKHH1	Q9ULM0	2	0	1	0.175	0.767	2	70.18185	2.350357	up_reg	4	0.2811106
297	KRT8	P05787	2	4632	6	0.432	0.721	1	76.32674	6.489903	up_reg	425	0.2808425
114	ITGB8	P26012	2	0	1	0.085	0.896	1	76.46707	2.820420	up_reg	131	0.2804622
182	TMC6	Q7Z403	2	761	2	0.125	0.830	6	72.55287	2.977559	up_reg	76	0.2802766
192	UPK3B	Q9BT76	2	0	1	0.394	0.821	1	52.89733	4.391774	up_reg	21	0.2790617
569	KIF14	Q15058	2	5312	10	0.127	0.506	1	66.04636	4.471441	up_reg	163	0.2775896
76	P2RY2	P41231	43	0	1	0.120	0.939	1	79.19662	4.039141	up_reg	470	0.2773580
57	IL32	P24001	2	0	1	0.099	0.950	2	71.19002	3.002851	up_reg	626	0.2771916
434	CCND1	P24385	2	30015	9	0.313	0.616	2	88.55158	3.545879	up_reg	6387	0.2771224
285	SPTBN2	O15020	2	4273	4	0.242	0.736	3	76.77521	4.481006	up_reg	98	0.2763568
31	HAS2	Q92819	2	0	1	0.103	0.970	1	90.70737	2.317929	up_reg	1108	0.2760892
123	LRP2	P98164	2	761	2	0.255	0.887	1	81.80994	4.927297	up_reg	452	0.2747911
18	IDO1	P14902	34	0	1	0.277	0.991	1	93.39839	5.743478	up_reg	2039	0.2747606
127	ESPL1	Q14674	2	0	1	0.619	0.885	1	75.77835	4.967101	up_reg	146	0.2743442
53	CYBB	P04839	2	1700	2	0.295	0.952	3	90.39584	2.576950	up_reg	2670	0.2736353
652	KIF18B	Q86Y91	2	764	11	0.200	0.437	1	62.74387	5.536292	up_reg	74	0.2735004
157	CXADR	P78310	2	0	1	0.405	0.860	1	79.48562	5.200874	up_reg	83	0.2732767
108	CDCP1	Q9H5V8	2	0	1	0.276	0.901	1	78.35387	5.466835	up_reg	234	0.2732558
110	MGST1	P10620	39	0	1	0.541	0.900	1	79.02661	3.365294	up_reg	238	0.2725864
218	NRAS	P01111	2	8745	6	0.256	0.798	1	92.29668	2.115169	up_reg	7121	0.2717905
608	CDK1	P06493	2	17675	13	0.514	0.471	1	89.31551	4.500461	up_reg	5957	0.2715876
72	TRPV6	Q9H1D0	2	0	1	0.341	0.941	3	80.74593	3.389083	up_reg	747	0.2707750
109	PBK	Q96KB5	2	0	2	0.152	0.901	1	84.90700	5.819542	up_reg	782	0.2707118
87	IFIT1	P09914	2	0	1	0.057	0.930	1	94.17439	2.860614	up_reg	577	0.2704904
66	GJB2	P29033	2	1520	2	0.236	0.943	2	86.38640	5.456850	up_reg	2564	0.2704582
196	NDUFB11	Q9NX14	2	0	1	0.410	0.818	1	78.63169	2.037892	up_reg	35	0.2700010
164	CACNA1A	O00555	2	4536	3	0.201	0.851	2	57.97536	2.232175	up_reg	1045	0.2683851
480	STAT1	P42224	2	28968	10	0.247	0.581	2	88.26074	2.024616	up_reg	12059	0.2683465
231	PIPOX	Q9P0Z9	2	453	2	0.845	0.789	3	94.41585	3.104421	up_reg	59	0.2674762
149	PYCR1	P32322	47	0	1	0.336	0.869	2	90.06781	2.897004	up_reg	158	0.2666917
188	KCNJ12	Q14500	2	0	1	0.160	0.823	2	81.21053	2.050148	up_reg	50	0.2664414
125	HMMR	O75330	2	0	1	0.192	0.886	2	76.10490	5.098101	up_reg	249	0.2662681
184	FSBP	O95073	2	0	1	0.297	0.828	1	70.03120	2.914093	up_reg	58	0.2661156
165	CXXC5	Q7LFL8	2	0	1	0.110	0.849	1	60.75966	4.423334	up_reg	99	0.2660937
67	PTGS1	P23219	2	0	2	0.142	0.943	1	94.11557	5.423793	up_reg	3039	0.2658601
100	LGALS9	O00182	2	0	1	0.247	0.914	3	85.12848	2.655331	up_reg	533	0.2653542
40	NQO1	P15559	2	761	2	0.254	0.963	1	98.32853	2.893693	up_reg	5539	0.2652253
195	ADGRE2	Q9UHX3	2	0	1	0.306	0.819	2	79.23141	2.147655	up_reg	49	0.2651575
176	IL27RA	Q6UWB1	2	761	2	0.336	0.833	1	79.02110	2.953478	up_reg	214	0.2650866
106	ASS1	P00966	2	0	1	0.103	0.902	1	95.63537	3.299729	up_reg	402	0.2650468
228	SECTM1	Q8WVN6	2	0	1	0.407	0.792	1	75.41749	2.268843	up_reg	26	0.2641929
258	ORC1	Q13415	2	2071	4	0.154	0.765	1	67.97461	2.787799	up_reg	375	0.2639238
152	LAPTM4B	Q86VI4	38	0	1	0.211	0.865	1	61.67725	3.214999	up_reg	179	0.2631116
56	DSP	P15924	2	2832	2	0.154	0.950	1	78.56539	4.716943	up_reg	5445	0.2628685
75	TNFSF10	P50591	2	761	2	0.184	0.940	1	82.39667	2.187216	up_reg	3737	0.2623053
305	KPNA2	P52292	2	2308	5	0.024	0.711	1	86.10732	3.953899	up_reg	312	0.2622117
119	GJB1	P08034	2	0	1	0.333	0.890	1	80.05050	7.474133	up_reg	358	0.2620922
191	FAM3B	P58499	30	0	1	0.319	0.821	2	93.09627	6.055449	up_reg	64	0.2617697
74	RORC	P51449	2	0	1	0.252	0.940	1	75.84376	4.448796	up_reg	1288	0.2616884
363	MRPS12	O15235	2	1743	3	0.312	0.667	1	87.35241	2.446360	up_reg	14	0.2590713
197	RASAL1	O95294	2	0	1	0.120	0.818	3	88.58747	6.257054	up_reg	78	0.2574562
840	AP1M2	Q9Y6Q5	2	7501	13	0.188	0.268	0	93.09129	8.570288	up_reg	40	0.2572337
290	ALDH3B2	P48448	5	0	2	0.218	0.732	2	94.98486	8.969782	up_reg	26	0.2568595
162	SLC7A7	Q9UM01	2	0	1	0.011	0.853	1	83.51919	2.184124	up_reg	198	0.2567099
130	BIK	Q13323	2	761	2	0.409	0.883	2	62.54290	6.029953	up_reg	1275	0.2566612
283	ASB9	Q96DX5	8	1	2	0.225	0.738	1	92.22385	2.355072	up_reg	31	0.2565489
262	TUBA1B	P68363	2	117	2	0.192	0.760	2	92.25708	2.287882	up_reg	57	0.2560003
493	CLDN6	P56747	2	4049	7	0.114	0.566	1	80.73011	12.449902	up_reg	114	0.2556876
187	GJB3	O75712	2	761	2	0.462	0.826	4	79.18052	6.360123	up_reg	328	0.2554962
334	SKA3	Q8IX90	2	4414	4	0.354	0.683	1	64.75869	5.662079	up_reg	97	0.2554939
322	NCAPD2	Q15021	2	0	3	0.115	0.697	1	79.98735	2.560562	up_reg	36	0.2544970
160	HTR3A	P46098	2	0	1	0.422	0.858	2	83.46451	10.598163	up_reg	265	0.2540779
256	FZD2	Q14332	2	1521	3	0.544	0.766	4	84.43777	2.649653	up_reg	254	0.2531729
83	IL2RA	P01589	2	0	1	0.000	0.936	1	72.50829	2.966958	up_reg	1993	0.2531247
194	BCL2L1	Q07817	2	2177	5	0.269	0.820	1	73.63605	2.256294	up_reg	8522	0.2529066
361	HDAC9	Q9UKV0	2	8	6	0.104	0.668	2	64.41926	2.313913	up_reg	455	0.2528179
223	DAPP1	Q9UN19	2	0	1	0.046	0.794	1	79.27173	3.771736	up_reg	58	0.2525156
229	SCARA3	Q6AZY7	50	0	1	0.222	0.790	4	71.06544	2.625480	up_reg	53	0.2523291
117	PTX3	P26022	2	135	2	0.266	0.891	2	79.75132	2.728436	up_reg	2010	0.2518234
323	PLPP2	O43688	45	1	2	0.205	0.694	1	85.85271	3.843634	up_reg	14	0.2510428
304	CACNG4	Q9UBN1	2	5285	2	0.125	0.712	1	65.72441	6.967106	up_reg	36	0.2503889
543	GNGT1	P63211	2	9443	6	0.318	0.524	1	88.83912	3.959000	up_reg	29	0.2503631
226	RTKN	Q9BST9	2	0	1	0.115	0.793	1	72.73822	2.656687	up_reg	69	0.2493868
183	IRF6	O14896	2	90	2	0.289	0.829	1	74.17857	3.540215	up_reg	507	0.2489293
350	PKMYT1	Q99640	2	16270	3	0.142	0.674	1	75.59028	5.618007	up_reg	107	0.2483895
219	NKG7	Q16617	2	0	1	0.270	0.797	1	86.50265	3.348089	up_reg	82	0.2482678
144	FUT2	Q10981	32	0	1	0.311	0.872	2	90.42101	2.453333	up_reg	560	0.2477669
292	NDUFA3	O95167	2	0	1	0.274	0.730	1	96.84498	2.073884	up_reg	15	0.2477448
169	LAMB3	Q13751	2	0	1	0.212	0.844	2	78.10768	4.685454	up_reg	288	0.2471542
268	NDUFB7	P17568	2	0	1	0.266	0.753	1	88.93270	2.055041	up_reg	31	0.2458810
281	ACOT4	Q8N9L9	3	0	1	0.140	0.740	1	96.46060	2.828725	up_reg	23	0.2452729
178	TYMP	P19971	46	0	1	0.402	0.833	2	93.01893	2.648306	up_reg	270	0.2437807
278	TXK	P42681	2	1520	2	0.210	0.743	1	80.40473	2.723460	up_reg	90	0.2437520
505	KIF2C	Q99661	2	8668	7	0.070	0.558	2	74.65762	4.503661	up_reg	295	0.2431291
359	APBB1IP	Q7Z5R6	2	5286	3	0.280	0.668	1	73.44023	2.145425	up_reg	56	0.2425592
150	IL23A	Q9NPF7	2	0	1	0.205	0.868	2	80.95746	2.267386	up_reg	706	0.2424748
212	ALG3	Q92685	6	0	1	0.084	0.800	1	89.19005	2.839320	up_reg	131	0.2420622
544	RBBP8	Q99708	2	4708	8	0.355	0.524	1	53.50791	2.260842	up_reg	287	0.2417188
37	VDR	P11473	2	0	1	0.284	0.966	1	84.69541	3.683154	up_reg	8882	0.2412780
171	SLC2A1	P11166	2	2279	3	0.190	0.839	1	89.61531	3.442262	up_reg	3562	0.2412211
356	DLGAP5	Q15398	2	4794	4	0.128	0.669	1	56.37102	5.302585	up_reg	180	0.2405725
491	HLA-DQA2	P01906	2	761	6	0.146	0.568	1	89.47761	4.305408	up_reg	88	0.2398315
220	SLC12A5	Q9H2X9	42	0	1	0.167	0.797	3	78.73929	2.764017	up_reg	143	0.2394734
217	MUC16	Q8WXI7	2	1521	3	0.180	0.798	1	55.96839	8.476038	up_reg	1352	0.2393358
153	SLC5A1	P13866	2	0	1	0.444	0.865	1	84.10975	6.574268	up_reg	812	0.2390450
490	FCGR1A	P12314	2	26802	5	0.350	0.568	2	84.96186	3.117302	up_reg	253	0.2387424
637	BLNK	Q8WV28	2	80581	4	0.308	0.447	1	64.71740	2.938435	up_reg	282	0.2386891
332	NCAPH	Q15003	2	0	3	0.198	0.683	1	60.71979	5.188544	up_reg	71	0.2382705
272	EYA2	O00167	28	2	2	0.223	0.748	1	69.03617	6.536633	up_reg	130	0.2380527
364	TMEM102	Q8N9M5	48	0	1	0.236	0.666	1	74.64646	3.553872	up_reg	5	0.2378005
185	RET	P07949	2	3789	4	0.127	0.827	1	79.44206	2.801801	up_reg	11194	0.2366877
180	WNT7B	P56706	2	0	1	0.461	0.832	2	89.56172	7.353727	up_reg	427	0.2360861
413	KRT6A	P02538	2	969	5	0.307	0.631	1	69.50787	3.041425	up_reg	196	0.2359403
374	XRCC2	O43543	2	761	5	0.516	0.659	1	87.09828	3.236290	up_reg	430	0.2343857
225	DSC3	Q14574	2	0	1	0.135	0.793	1	74.81262	2.160385	up_reg	181	0.2341352
267	LMNB1	P20700	2	325	2	0.275	0.754	2	82.63466	3.288592	up_reg	199	0.2340999
803	KIF6	Q6ZMV9	2	0	12	0.091	0.302	0	71.56561	2.593490	up_reg	83	0.2334100
161	PROM1	O43490	2	335	2	0.171	0.857	2	85.89768	5.868539	up_reg	2840	0.2329564
340	PIK3CG	P48736	2	9360	4	0.145	0.681	2	88.42052	2.098934	up_reg	562	0.2329258
252	WDR62	O43379	2	0	1	0.088	0.770	2	61.36502	3.041289	up_reg	124	0.2309319
203	CXCL16	Q9H2A7	2	40	2	0.204	0.808	2	65.97562	3.366446	up_reg	927	0.2308495
189	LAMC2	Q13753	2	0	1	0.153	0.822	1	74.86195	4.997825	up_reg	472	0.2304904
250	FGF18	O76093	2	620	2	0.380	0.771	2	87.67060	5.957364	up_reg	396	0.2303223
132	CIT	O14578	2	4278	2	0.129	0.882	1	70.15278	3.109393	up_reg	8634	0.2301055
200	BMP7	P18075	12	7	3	0.232	0.814	2	76.70694	7.157820	up_reg	3269	0.2297713
282	RGS19	P49795	2	0	1	0.119	0.740	2	79.47628	3.524701	up_reg	63	0.2296172
246	CHAC1	Q9BUX1	17	0	1	0.391	0.775	1	86.16639	2.901424	up_reg	155	0.2293957
307	GPR19	Q15760	27	0	1	0.271	0.708	2	74.77012	5.197318	up_reg	30	0.2283877
261	PAK6	Q9NQU5	2	0	1	0.452	0.760	4	67.07498	3.389624	up_reg	123	0.2270601
214	NOTUM	Q6P988	2	0	1	0.466	0.800	1	84.58992	7.917860	up_reg	341	0.2268665
284	UNC5A	Q6ZN44	2	0	1	0.108	0.737	1	78.25560	5.877999	up_reg	71	0.2265372
496	MARVELD2	Q8N4S9	2	3133	5	0.305	0.564	1	67.20563	5.592913	up_reg	78	0.2264109
242	RAB27B	O00194	2	0	1	0.070	0.777	1	86.79901	2.886397	up_reg	230	0.2239298
232	FUT1	P19526	32	0	1	0.333	0.788	1	88.46001	2.677239	up_reg	317	0.2232279
728	KIF1A	Q12756	2	0	11	0.106	0.373	0	71.01825	4.710262	up_reg	351	0.2222732
286	CD109	Q6YHK3	2	761	2	0.287	0.734	2	81.37547	2.781852	up_reg	265	0.2220890
368	FOLR1	P15328	2	608	4	0.090	0.662	1	91.11366	9.610444	up_reg	357	0.2216913
346	TRIP13	Q15645	2	1521	3	0.249	0.677	2	86.97940	3.848280	up_reg	197	0.2216112
412	CLDN3	O15551	2	669	5	0.271	0.631	1	81.42759	10.441852	up_reg	485	0.2211545
249	GZMB	P10144	2	2279	3	0.347	0.774	1	92.52045	4.083414	up_reg	2459	0.2211340
390	PARD6B	Q9BYG5	2	3192	2	0.345	0.647	1	71.24402	3.304514	up_reg	40	0.2201530
301	POLQ	O75417	2	0	2	0.104	0.717	1	59.48627	3.988411	up_reg	184	0.2201409
475	RACGAP1	Q9H0H5	2	1421	5	0.133	0.584	2	69.86318	3.466668	up_reg	173	0.2196828
277	CBLC	Q9ULV8	2	102	2	0.215	0.744	1	81.16177	8.008650	up_reg	381	0.2194943
530	SMC4	Q9NTJ3	2	4021	6	0.294	0.533	3	81.89970	2.074392	up_reg	175	0.2189937
388	TMEM63C	Q9P1W3	2	0	1	0.125	0.649	1	74.57350	3.490019	up_reg	12	0.2186591
274	CD180	Q99467	15	0	1	0.355	0.747	1	93.23928	3.301753	up_reg	151	0.2186104
198	CYC1	P08574	2	0	1	0.109	0.817	1	86.38440	2.331383	up_reg	883	0.2185086
302	MGST2	Q99735	39	0	1	0.330	0.715	1	93.94066	2.026180	up_reg	69	0.2181868
306	SHCBP1	Q8NEM2	2	0	1	0.180	0.711	1	73.69646	2.980451	up_reg	65	0.2175260
216	TREM2	Q9NZC2	2	0	2	0.411	0.799	1	77.04992	3.818614	up_reg	1706	0.2174719
170	POSTN	Q15063	2	0	1	0.152	0.839	2	80.24478	2.937741	up_reg	1643	0.2174055
331	GRIN2A	Q12879	2	4542	3	0.064	0.686	1	60.41927	3.737127	up_reg	429	0.2165816
333	RAB6B	Q9NRW1	2	0	1	0.239	0.683	1	86.02474	2.332450	up_reg	35	0.2160010
209	TRPV4	Q9HBA0	2	761	2	0.132	0.803	5	72.00033	3.177434	up_reg	2211	0.2158796
269	CCR1	P32246	2	719	3	0.143	0.752	1	83.11436	2.538960	up_reg	1807	0.2153133
311	CMPK2	Q5EBM0	21	0	1	0.064	0.706	2	87.31019	3.113808	up_reg	67	0.2150495
383	SHISA9	B4DS77	2	0	1	0.277	0.654	1	56.95488	5.720736	up_reg	18	0.2146018
416	SYNE4	Q8N205	11	0	1	0.168	0.628	1	57.78246	4.109102	up_reg	9	0.2144468
330	CSPG5	O95196	2	0	1	0.081	0.686	1	52.88670	4.429149	up_reg	42	0.2143649
884	H2AC8	P04908	2	12365	8	0.384	0.231	0	91.08903	2.068346	up_reg	1	0.2133477
402	GINS4	Q9BRT9	2	0	2	0.324	0.635	1	90.74832	2.575322	up_reg	36	0.2130303
427	ACKR2	O00590	2	3092	3	0.220	0.621	2	80.01695	4.237197	up_reg	100	0.2119053
247	TNFSF15	O95150	2	0	1	0.272	0.775	2	82.11392	4.283946	up_reg	467	0.2118600
653	WAS	P42768	2	2279	3	0.258	0.437	1	70.12989	2.016246	up_reg	0	0.2109615
460	UNC5B	Q8IZJ1	2	6797	4	0.216	0.597	1	77.98145	2.185793	up_reg	231	0.2102958
456	CENPK	Q9BS16	2	0	3	0.253	0.599	1	81.70731	3.365918	up_reg	50	0.2101747
325	CD8A	P01732	2	558	3	0.263	0.692	1	79.23665	2.123590	up_reg	573	0.2094271
471	CXCR4	P61073	2	10567	8	0.122	0.585	1	82.80839	3.415298	up_reg	15921	0.2093435
313	FOXM1	Q08050	2	1527	4	0.173	0.701	1	51.07629	5.310591	up_reg	2251	0.2090775
308	SPC25	Q9HBM1	2	0	1	0.390	0.708	1	90.25548	4.349788	up_reg	106	0.2086137
320	FYB1	O15117	2	0	1	0.418	0.698	1	58.39229	2.503950	up_reg	86	0.2079165
287	FUT3	P21217	30	0	1	0.263	0.734	2	90.59422	4.921716	up_reg	215	0.2078015
389	DLGAP3	O95886	2	0	1	0.282	0.648	1	50.70109	3.775359	up_reg	25	0.2071953
381	NCAPG	Q9BPX3	2	0	3	0.163	0.655	1	82.50230	4.802859	up_reg	252	0.2070111
251	ST14	Q9Y5Y6	51	0	1	0.160	0.771	2	81.25730	7.158208	up_reg	577	0.2068904
477	H4C3	P62805	2	0	1	0.336	0.581	1	90.43752	6.938438	up_reg	4	0.2067106
391	COL13A1	Q5TAT6	1	0	2	0.197	0.646	1	57.97463	2.870544	up_reg	75	0.2059408
245	PIGR	P01833	35	0	1	0.017	0.776	1	77.21791	3.975115	up_reg	702	0.2057654
380	CHST4	Q8NCG5	18	0	1	0.363	0.655	2	90.77228	5.171505	up_reg	34	0.2052506
581	KIF23	Q02241	2	5487	6	0.314	0.498	1	73.07353	3.446904	up_reg	207	0.2041465
264	SLC7A11	Q9UPY5	2	761	2	0.376	0.758	3	86.60983	2.106353	up_reg	1518	0.2038788
395	CDR2L	Q86X02	2	0	1	0.434	0.641	2	74.20117	3.691110	up_reg	26	0.2037929
665	GATA3	P23771	2	29626	9	0.110	0.426	1	58.31754	3.618532	up_reg	5363	0.2034283
455	PYCR3	Q53H96	47	0	1	0.416	0.600	1	94.81272	2.239585	up_reg	9	0.2032468
399	ADD2	P35612	2	761	2	0.203	0.639	4	66.27120	3.978666	up_reg	80	0.2030682
404	GPRIN2	O60269	2	0	1	0.172	0.634	1	50.28259	4.769083	up_reg	23	0.2028729
235	MX2	P20592	2	0	1	0.177	0.784	1	78.01712	2.755543	up_reg	1098	0.2018337
257	LGR5	O75473	37	3	2	0.267	0.766	4	80.74472	3.946516	up_reg	2020	0.2015804
519	ITGA3	P26006	2	2794	5	0.183	0.545	2	84.16933	2.090433	up_reg	228	0.2014026
387	ROMO1	P60602	2	636	2	0.413	0.649	3	78.13109	2.159277	up_reg	115	0.2011806
570	ITGB4	P16144	2	8018	6	0.154	0.505	1	69.97733	3.972681	up_reg	363	0.2011550
457	HOMER2	Q9NSB8	2	1521	3	0.431	0.599	2	89.11372	3.173158	up_reg	101	0.2009985
394	PCNA	P12004	2	4677	7	0.569	0.642	1	94.33015	2.104983	up_reg	25415	0.2007025
443	MPP7	Q5T2T1	2	322	2	0.114	0.606	1	81.02127	2.488989	up_reg	39	0.2005855
445	CD74	P04233	2	3917	5	0.198	0.605	1	70.67138	3.873722	up_reg	1184	0.2005588
291	BTC	P35070	2	2783	3	0.290	0.731	1	72.38943	2.703718	up_reg	3190	0.2004066
641	ZNF217	O75362	2	6359	7	0.240	0.445	1	50.34735	2.073407	up_reg	219	0.1998000
386	RNF43	Q68DV7	37	0	3	0.124	0.651	1	54.60221	2.425714	up_reg	369	0.1993438
514	MCM10	Q7L590	2	0	5	0.080	0.549	2	66.88891	4.376528	up_reg	231	0.1993275
362	KIF4A	O95239	2	1470	2	0.244	0.668	3	72.17122	5.153087	up_reg	226	0.1990995
576	ERBB3	P21860	2	19657	7	0.108	0.502	1	72.82537	4.895964	up_reg	2709	0.1990216
593	CDCA8	Q53HL2	2	6045	6	0.388	0.483	1	68.78919	4.987197	up_reg	205	0.1989932
733	PIERCE1	Q5BN46	2	0	6	0.223	0.365	0	76.89413	3.026062	up_reg	6	0.1982733
310	FANCA	O15360	2	2277	2	0.135	0.707	1	74.56587	2.596562	up_reg	687	0.1980021
384	HLA-DRA	P01903	2	0	4	0.277	0.653	1	89.58587	3.994244	up_reg	1221	0.1977404
435	DCTPP1	Q9H773	21	0	1	0.339	0.616	1	85.40514	2.697626	up_reg	24	0.1950213
241	CDC25C	P30307	2	0	1	0.362	0.777	1	64.18249	6.227772	up_reg	1461	0.1944782
419	KRT17	Q04695	2	81	3	0.276	0.626	1	79.60908	6.228925	up_reg	271	0.1943558
438	CENPN	Q96H22	2	0	2	0.300	0.612	1	86.20997	2.369029	up_reg	68	0.1938832
555	CENPM	Q9NSP4	2	439	4	0.181	0.514	1	89.76468	4.526135	up_reg	49	0.1937023
393	FOLH1	Q04609	2	2288	4	0.322	0.643	1	94.01397	2.144560	up_reg	1490	0.1934041
453	CCL4L2	Q8NHW4	2	0	1	0.140	0.601	1	90.27970	2.125786	up_reg	18	0.1934018
295	BCAM	P50895	2	0	1	0.182	0.725	3	84.58449	4.415965	up_reg	425	0.1933609
259	ALPL	P05186	2	0	1	0.370	0.761	2	93.75407	4.455983	up_reg	1060	0.1931954
336	ATP2B2	Q01814	2	0	1	0.151	0.681	2	73.94863	4.507063	up_reg	155	0.1917957
211	SMAD1	Q15797	2	0	1	0.240	0.801	1	81.78024	2.105853	up_reg	3204	0.1915497
719	TEKT2	Q9UIF3	2	0	6	0.320	0.382	0	91.10427	3.432483	up_reg	16	0.1909104
396	DMTN	Q08495	2	0	1	0.221	0.641	1	64.63463	3.098244	up_reg	60	0.1907835
474	NRARP	Q7Z6K4	2	1520	2	0.142	0.584	1	82.92880	3.105494	up_reg	46	0.1906981
376	NEK2	P51955	2	7688	2	0.136	0.658	2	78.74819	6.921414	up_reg	489	0.1905342
398	RAD51	Q06609	2	4984	5	0.282	0.640	1	91.59067	3.625870	up_reg	5831	0.1904461
596	MRPL13	Q9BYD1	2	2181	4	0.371	0.481	1	93.49656	2.310295	up_reg	32	0.1892964
319	CD7	P09564	2	1521	3	0.383	0.699	2	77.62312	2.751900	up_reg	2691	0.1887548
531	MLF1	P58340	2	799	4	0.247	0.532	1	65.94371	2.278928	up_reg	110	0.1886195
527	TTC30B	Q8N4P2	55	0	1	0.170	0.535	2	93.27146	2.933139	up_reg	4	0.1883106
411	SLC44A4	Q53GD3	2	0	1	0.128	0.632	1	83.76549	4.642249	up_reg	56	0.1882661
326	IL1RAP	Q9NPH3	2	0	1	0.211	0.692	1	86.22484	3.030829	up_reg	257	0.1881654
321	EGLN3	Q9H6Z9	2	0	1	0.068	0.697	3	91.56092	3.193540	up_reg	295	0.1879722
466	IFI44L	Q53G44	2	1520	3	0.257	0.590	1	86.36570	2.148762	up_reg	185	0.1878079
343	CCDC6	Q16204	2	0	1	0.565	0.678	2	76.03680	2.126289	up_reg	199	0.1866299
430	CABP4	P57796	2	0	1	0.276	0.620	1	66.10069	2.568051	up_reg	49	0.1855575
441	IL2RG	P31785	2	2925	4	0.234	0.609	1	76.81580	2.149183	up_reg	1136	0.1849210
414	L1CAM	P32004	2	5550	4	0.068	0.631	1	79.35279	3.823699	up_reg	2439	0.1847902
358	RAD54L	Q92698	2	0	1	0.171	0.669	1	80.51223	4.209123	up_reg	180	0.1846232
431	C1QC	P02747	2	940	2	0.290	0.619	1	81.16742	2.927810	up_reg	159	0.1844248
420	PLAU	P00749	2	998	3	0.414	0.626	1	82.30347	3.727477	up_reg	569	0.1836847
369	RAB3D	O95716	48	0	1	0.185	0.662	2	85.15368	2.740453	up_reg	166	0.1831082
415	NETO2	Q8NC67	42	0	1	0.302	0.631	1	72.42280	2.079967	up_reg	77	0.1828595
640	NEIL3	Q8TAT5	2	1223	6	0.015	0.445	1	70.00855	5.418772	up_reg	151	0.1826614
529	THEM6	Q8WUY1	2	0	1	0.187	0.534	1	94.93291	3.578714	up_reg	6	0.1825400
449	CDK2AP2	O75956	16	0	1	0.476	0.603	1	75.74548	2.120070	up_reg	40	0.1819251
314	CRB3	Q9BUF7	2	0	1	0.297	0.700	1	70.34841	6.178867	up_reg	484	0.1812905
488	GPSM3	Q9Y4H4	2	0	1	0.281	0.570	1	71.62680	2.087401	up_reg	18	0.1810018
266	THY1	P04216	2	761	2	0.334	0.756	1	83.05667	3.086846	up_reg	6210	0.1806004
338	KCP	Q6ZWJ8	12	0	1	0.112	0.681	2	72.93541	4.945915	up_reg	315	0.1805286
349	BCAT1	P54687	10	0	1	0.358	0.674	1	95.00595	2.614531	up_reg	265	0.1804779
409	CDK2AP1	O14519	16	0	1	0.451	0.632	1	76.36776	3.230913	up_reg	92	0.1804520
324	STIL	Q15468	2	0	1	0.163	0.693	1	53.64950	3.519855	up_reg	469	0.1789920
469	OAS2	P29728	19	2	3	0.270	0.588	1	87.74127	4.206419	up_reg	278	0.1786521
513	ALDH3B1	P43353	5	0	2	0.048	0.550	1	96.26882	2.749792	up_reg	38	0.1781900
433	BLM	P54132	2	1899	5	0.161	0.616	1	60.95775	3.668059	up_reg	5420	0.1781841
248	CCR5	P51681	2	119	2	0.253	0.774	1	85.29439	2.420445	up_reg	10827	0.1781320
365	CAPG	P40121	2	0	1	0.313	0.665	1	86.70529	3.387519	up_reg	249	0.1778681
298	OSM	P13725	2	1111	2	0.107	0.721	1	79.62908	2.173526	up_reg	3150	0.1778664
344	USP18	Q9UMW8	2	0	1	0.065	0.678	1	84.05593	3.392279	up_reg	351	0.1776065
382	BAK1	Q16611	2	2279	3	0.535	0.654	2	81.54397	2.273926	up_reg	1896	0.1772822
437	CKAP2	Q8WWK9	19	0	1	0.332	0.615	2	59.53707	2.952651	up_reg	74	0.1770856
276	AMN	Q9BXJ7	2	0	1	0.320	0.745	1	80.93990	5.031542	up_reg	1960	0.1769911
492	ELMO3	Q96BJ8	2	0	1	0.169	0.567	2	89.19677	3.013380	up_reg	22	0.1767522
300	MMP9	P14780	2	4920	4	0.191	0.717	2	82.25628	5.237949	up_reg	34223	0.1762547
462	B3GNT2	Q9NY97	2	0	1	0.183	0.592	1	91.28206	2.353972	up_reg	44	0.1760392
852	KIF18A	Q8NI77	2	2337	10	0.186	0.256	0	67.74104	4.341757	up_reg	144	0.1758631
379	TPX2	Q9ULW0	2	761	2	0.402	0.656	1	64.23851	6.263362	up_reg	684	0.1757905
717	KRT23	Q9C075	2	1409	6	0.182	0.382	0	78.43096	7.803255	up_reg	48	0.1757618
647	GINS3	Q9BRX5	2	2215	4	0.238	0.441	1	88.16138	2.227008	up_reg	28	0.1754010
347	HAVCR2	Q8TDQ0	2	1520	2	0.115	0.676	2	71.85756	2.594164	up_reg	1252	0.1750935
318	CD6	P30203	2	0	1	0.079	0.699	1	66.69789	2.141497	up_reg	697	0.1750793
504	DSCC1	Q9BVC3	2	0	1	0.206	0.558	1	92.16572	2.243598	up_reg	20	0.1746043
502	RSPO4	Q2I0M5	37	0	2	0.197	0.559	1	78.73711	3.739053	up_reg	61	0.1743906
351	WNT10A	Q9GZT5	2	0	1	0.100	0.672	1	80.83386	7.182905	up_reg	400	0.1731262
451	HOOK1	Q9UJC3	2	0	1	0.269	0.603	3	82.67534	3.529558	up_reg	73	0.1724998
524	CITED4	Q96RK1	2	761	2	0.279	0.537	1	61.06457	3.902872	up_reg	42	0.1723759
568	PTPN6	P29350	2	2507	6	0.243	0.507	1	86.41216	3.217645	up_reg	1532	0.1721658
459	RCOR2	Q8IZ40	2	0	1	0.110	0.597	1	68.12330	3.046027	up_reg	65	0.1719260
470	UBASH3B	Q8TF42	2	0	1	0.138	0.588	2	85.36864	2.937062	up_reg	54	0.1712362
468	CASP8	Q14790	2	5020	5	0.223	0.589	2	81.49031	2.275285	up_reg	5488	0.1710582
499	PACSIN1	Q9BY11	2	761	2	0.285	0.562	1	85.39394	2.524601	up_reg	88	0.1707648
448	IQGAP3	Q86VI3	2	0	1	0.181	0.604	2	79.62675	5.163314	up_reg	85	0.1705011
397	IGF2BP2	Q9Y6M1	2	761	2	0.107	0.640	1	77.75247	2.401479	up_reg	650	0.1702031
454	DSC2	Q02487	2	3552	2	0.275	0.600	1	76.56279	5.332860	up_reg	297	0.1701394
518	ERCC6L	Q2NKX8	2	761	2	0.048	0.546	1	62.79458	2.571255	up_reg	62	0.1698796
425	PCP4	P48539	44	0	1	0.348	0.623	1	77.79623	3.572944	up_reg	144	0.1697629
328	LDHA	P00338	2	0	2	0.089	0.690	1	96.06050	2.195336	up_reg	2225	0.1696345
487	GMNC	A6NCL1	2	0	1	0.280	0.572	1	59.65300	6.567087	up_reg	40	0.1695251
693	MRPL14	Q6P1L8	2	231	4	0.335	0.400	1	86.22027	2.510977	up_reg	12	0.1693457
619	OCLN	Q16625	2	4018	7	0.030	0.464	1	65.47618	3.942788	up_reg	1993	0.1693110
533	LSR	Q86X29	2	4740	5	0.029	0.531	2	57.32796	5.010835	up_reg	1449	0.1687587
550	PKM	P14618	2	3037	5	0.224	0.522	2	96.78672	2.561725	up_reg	1019	0.1686600
556	KRT15	P19012	2	4	4	0.359	0.513	1	77.14245	3.112879	up_reg	229	0.1684040
497	P2RY6	Q15077	43	0	1	0.257	0.563	1	85.89765	4.546917	up_reg	35	0.1680010
484	SIGLEC14	Q08ET2	2	0	1	0.311	0.576	1	83.53957	2.119134	up_reg	49	0.1679575
410	KCNN4	O15554	2	761	2	0.429	0.632	1	84.85052	3.886967	up_reg	641	0.1672253
405	TEC	P42680	2	2277	4	0.096	0.634	1	85.88542	2.329341	up_reg	6593	0.1660599
674	BICDL2	A1A5D9	11	0	1	0.351	0.415	1	80.82586	5.705336	up_reg	0	0.1660000
458	C1QA	P02745	2	1659	2	0.216	0.597	1	82.87227	2.309558	up_reg	313	0.1657554
432	MAL2	Q969L2	2	0	1	0.336	0.619	1	84.15024	8.534437	up_reg	176	0.1649799
500	RPS6KA1	Q15418	2	3340	3	0.060	0.562	3	77.46253	2.996836	up_reg	451	0.1646935
452	VAV1	P15498	2	853	3	0.182	0.602	2	87.14542	2.680345	up_reg	1025	0.1645227
757	ENKUR	Q8TC29	2	0	5	0.369	0.346	0	87.21706	2.841760	up_reg	12	0.1641257
426	NUF2	Q9BZD4	2	0	1	0.317	0.622	2	89.42833	4.636580	up_reg	201	0.1640711
575	CDH6	P55285	2	3554	3	0.178	0.502	1	78.76359	5.541725	up_reg	108	0.1636619
392	AQP5	P55064	2	761	2	0.392	0.643	1	93.50506	7.968789	up_reg	1158	0.1621963
660	SMKR1	H3BMG3	2	0	1	0.229	0.430	1	70.64355	5.083228	up_reg	1	0.1609362
747	KIFC1	Q9BW19	2	2554	7	0.202	0.353	0	77.88326	3.454857	up_reg	186	0.1608721
509	NGEF	Q8N5V2	2	0	1	0.181	0.553	1	72.01310	2.849246	up_reg	50	0.1584414
508	MAP4K1	Q92918	2	0	1	0.100	0.553	2	69.28828	2.859794	up_reg	52	0.1578274
612	DEPDC1B	Q8WUY9	2	444	3	0.107	0.469	1	77.36351	4.803039	up_reg	54	0.1575205
788	CLSPN	Q9HAW4	2	7028	7	0.285	0.322	0	51.81036	5.405931	up_reg	151	0.1573320
447	ESRP1	Q6NXG1	2	0	1	0.187	0.604	1	78.06816	8.042375	up_reg	197	0.1571903
486	RAD54B	Q9Y620	2	0	1	0.092	0.573	1	71.80594	2.894284	up_reg	91	0.1570246
985	VAV3	Q9UKW4	2	68848	8	0.067	0.117	0	84.41551	4.547079	up_reg	321	0.1567345
812	CXCL17	Q6UXB2	2	11398	7	0.060	0.292	0	59.53315	7.541358	up_reg	104	0.1566597
436	SLC34A2	O95436	2	0	1	0.040	0.616	3	72.96990	7.493592	up_reg	287	0.1560096
535	KRT18	P05783	2	5320	3	0.125	0.530	1	80.29975	5.341706	up_reg	409	0.1559073
446	CD96	P40200	2	0	1	0.113	0.605	1	66.54424	2.031664	up_reg	234	0.1548558
407	MYBL2	P10244	2	0	1	0.066	0.633	1	58.45051	6.939571	up_reg	478	0.1546892
699	SORT1	Q99523	2	2539	6	0.176	0.394	0	83.49614	2.686299	up_reg	283	0.1539170
525	ECT2	Q9H8V3	2	463	3	0.116	0.537	1	71.66219	4.589366	up_reg	384	0.1536841
584	CYRIB	Q9NUQ9	2	0	1	0.134	0.494	1	92.17381	2.720870	up_reg	15	0.1533448
516	BARX2	Q9UMQ3	2	0	1	0.238	0.548	1	66.35156	7.021298	up_reg	61	0.1533239
557	MPZL3	Q6UWV2	40	0	1	0.289	0.513	1	80.77116	2.509616	up_reg	25	0.1531953
547	CDK5	Q00535	2	4541	5	0.253	0.522	1	91.44164	2.814439	up_reg	3067	0.1529490
668	ORC6	Q9Y5N6	2	4900	4	0.216	0.425	1	81.54463	3.385301	up_reg	101	0.1522584
371	TREM1	Q9NP99	2	0	1	0.034	0.660	1	71.42913	3.025812	up_reg	1118	0.1519459
553	KCTD1	Q719H9	2	0	1	0.380	0.519	1	87.09265	3.190517	up_reg	35	0.1504010
628	CEBPA	P49715	2	18094	5	0.467	0.453	1	63.67368	3.364331	up_reg	1906	0.1497578
329	TNFRSF11B	O00300	2	0	1	0.349	0.688	1	87.00873	4.469606	up_reg	2628	0.1495119
638	CXCL14	O95715	2	2123	5	0.298	0.447	1	85.46693	2.064284	up_reg	483	0.1494247
682	TPD52	P55327	2	761	5	0.350	0.412	1	68.17637	4.269727	up_reg	183	0.1491719
790	CLDN9	O95484	2	0	6	0.387	0.320	0	81.18086	7.555719	up_reg	51	0.1482648
532	NDC80	O14777	2	2922	3	0.161	0.532	2	78.60958	4.044795	up_reg	592	0.1478410
554	S100A4	P26447	2	7702	4	0.313	0.516	1	85.18673	3.072037	up_reg	1705	0.1471726
489	LTF	P02788	2	2076	3	0.410	0.569	1	95.06001	5.560156	up_reg	1484	0.1469387
406	CD2	P06729	2	97	4	0.375	0.633	2	78.29759	3.177594	up_reg	18110	0.1468275
482	NOS1AP	O75052	2	0	1	0.211	0.579	1	66.16135	2.421510	up_reg	221	0.1453641
523	PTPN3	P26045	2	0	1	0.087	0.538	1	73.60570	2.860009	up_reg	82	0.1446678
498	E2F8	A0AVK6	2	0	1	0.140	0.562	1	53.69316	6.360635	up_reg	151	0.1446104
355	SELL	P14151	2	714	2	0.321	0.670	1	85.32516	2.655413	up_reg	6836	0.1446093
691	ZC2HC1C	Q53FD0	55	0	1	0.370	0.403	1	61.17503	2.306638	up_reg	2	0.1436643
629	RAB3IP	Q96QF0	48	1	2	0.090	0.453	1	72.31525	2.494769	up_reg	30	0.1430557
580	EVPL	Q92817	2	0	1	0.174	0.499	1	73.17542	5.384071	up_reg	34	0.1428506
572	PTTG1	O95997	2	3399	3	0.339	0.504	1	64.54399	5.620004	up_reg	437	0.1420689
461	APOBEC3B	Q9UH17	2	0	1	0.283	0.593	1	88.33103	4.139712	up_reg	399	0.1415661
501	ENHO	Q6UWT2	27	0	1	0.408	0.561	2	75.10782	3.532277	up_reg	183	0.1411608
602	LEF1	Q9UJU2	2	4131	5	0.140	0.477	1	57.83920	3.139927	up_reg	2086	0.1405903
540	EGFL6	Q8IUX8	26	0	1	0.125	0.526	1	67.15563	6.860705	up_reg	84	0.1394878
551	LAIR1	Q6GTX8	2	174	2	0.416	0.521	1	71.90481	2.172930	up_reg	216	0.1394103
465	CXCR3	P49682	2	1658	3	0.210	0.590	1	80.64541	4.557329	up_reg	4275	0.1379388
521	HLA-DMB	P28068	2	0	2	0.451	0.541	1	89.04596	2.973875	up_reg	427	0.1363528
517	TNFRSF9	Q07011	2	761	2	0.306	0.548	2	81.76231	5.502102	up_reg	554	0.1359496
440	SLPI	P03973	2	0	1	0.442	0.612	1	84.39588	7.842239	up_reg	928	0.1357160
943	NDUFA4L2	Q9NRX3	2	9789	8	0.201	0.175	0	84.63933	2.341067	up_reg	53	0.1351438
545	NELL2	Q99435	14	0	1	0.254	0.523	1	80.32717	2.349571	up_reg	103	0.1350677
656	COL23A1	Q86Y22	1	0	2	0.185	0.433	1	60.28518	4.830819	up_reg	30	0.1350544
810	MYL11	Q96A32	2	761	2	0.286	0.293	0	84.57639	3.638218	up_reg	0	0.1348111
539	IL2RB	P14784	2	377	2	0.064	0.528	1	65.81703	3.612277	up_reg	374	0.1337307
418	CCL4	P13236	2	2410	3	0.270	0.626	1	88.97642	3.213667	up_reg	14603	0.1336666
605	SH3BGRL3	Q9H299	44	0	1	0.301	0.475	1	96.43171	2.275968	up_reg	34	0.1332506
507	TK1	P04183	2	28	2	0.284	0.554	2	82.30998	5.569907	up_reg	778	0.1320283
773	SERPINA1	P01009	2	20309	6	0.431	0.336	0	89.00521	4.107159	up_reg	1052	0.1318528
670	CKS1B	P61024	2	9359	3	0.172	0.423	1	92.17249	2.929388	up_reg	191	0.1302292
819	UBE2C	O00762	2	23230	6	0.355	0.286	0	89.69871	6.912778	up_reg	434	0.1295887
552	PTPRF	P10586	2	0	1	0.303	0.521	3	82.86021	2.388058	up_reg	139	0.1295230
627	CLIC5	Q9NZA1	2	760	2	0.184	0.454	1	68.21008	5.435746	up_reg	79	0.1292653
546	TM4SF1	P30408	2	0	1	0.246	0.523	1	81.27962	2.530357	up_reg	151	0.1290104
473	BCL11A	Q9H165	2	0	1	0.176	0.584	3	52.46475	5.681517	up_reg	706	0.1288748
654	NAA38	Q9BRA0	2	0	1	0.488	0.435	1	79.30929	2.165583	up_reg	16	0.1287771
510	EXO1	Q9UQ84	2	0	2	0.203	0.552	1	63.63935	4.665404	up_reg	924	0.1284516
481	CA9	Q16790	2	761	2	0.253	0.580	2	76.98377	4.198252	up_reg	2015	0.1281606
620	CNKSR1	Q969H4	2	0	1	0.212	0.463	1	68.49088	2.403831	up_reg	35	0.1280010
739	CLDN4	O14493	2	2764	6	0.511	0.360	0	84.52154	7.966261	up_reg	627	0.1279296
377	TLR7	Q9NYK1	54	0	1	0.198	0.657	4	87.54334	3.806294	up_reg	4757	0.1276430
666	HOXB6	P17509	2	0	3	0.098	0.426	1	66.54839	5.256411	up_reg	118	0.1274504
506	ZBP1	Q9H171	2	0	1	0.155	0.556	1	55.84276	4.315149	up_reg	389	0.1271702
563	TNFRSF13C	Q96RJ3	2	388	2	0.223	0.511	1	64.47587	2.730865	up_reg	371	0.1270726
522	MICB	Q29980	2	117	2	0.152	0.538	1	78.97880	2.653896	up_reg	735	0.1266450
463	KCNJ11	Q14654	2	0	1	0.126	0.592	1	84.56523	2.949554	up_reg	1019	0.1262244
927	POLR2F	P61218	2	3038	7	0.081	0.195	0	79.10277	4.942004	up_reg	32	0.1259599
697	MRPL15	Q9P015	2	0	2	0.439	0.396	0	91.01003	2.252783	up_reg	21	0.1257284
623	SPON1	Q9HCB6	2	761	2	0.074	0.461	1	77.42394	3.386911	up_reg	119	0.1255946
746	CENPW	Q5EE01	2	0	4	0.310	0.353	0	89.69919	3.831944	up_reg	60	0.1255835
725	ZNF726	A6NNF4	56	0	1	0.407	0.377	0	70.98692	2.195829	up_reg	4	0.1251106
495	GZMA	P12544	2	0	1	0.340	0.564	2	91.46294	2.555949	up_reg	557	0.1246525
574	LPAR3	Q9UBY5	2	0	1	0.018	0.503	1	81.89258	4.654211	up_reg	129	0.1235059
651	KRT5	P13647	2	0	4	0.423	0.438	1	68.77450	4.040272	up_reg	612	0.1227520
536	LINGO1	Q96FE5	2	0	1	0.222	0.530	2	86.97018	3.398463	up_reg	268	0.1226989
537	TYMS	P04818	2	0	2	0.380	0.529	1	94.13606	2.197956	up_reg	818	0.1211943
681	LLGL2	Q6P1M3	2	761	2	0.114	0.412	2	85.39241	2.400335	up_reg	46	0.1209562
408	CD24	P25063	2	0	1	0.228	0.632	1	63.89011	8.713693	up_reg	4011	0.1203651
611	NDUFS8	O00217	2	0	1	0.547	0.470	1	89.19101	2.656440	up_reg	70	0.1199604
751	VAMP8	Q9BV40	2	3785	5	0.286	0.350	0	90.45868	4.647834	up_reg	317	0.1193917
685	NRG4	Q8WWG1	2	0	3	0.403	0.409	1	78.48852	2.336379	up_reg	130	0.1191169
541	SCNN1A	P37088	2	0	1	0.225	0.525	1	75.79274	5.496125	up_reg	300	0.1189049
589	FGFR3	P22607	2	2641	4	0.127	0.488	1	75.36964	3.476785	up_reg	3416	0.1186048
625	FAM83D	Q9H4H8	2	0	1	0.140	0.459	1	64.42717	5.053814	up_reg	58	0.1185156
578	GIPC1	O14908	2	0	1	0.347	0.501	1	81.65762	2.472014	up_reg	174	0.1179613
560	PCDH19	Q8TAB3	2	0	1	0.156	0.512	1	68.74772	2.531005	up_reg	242	0.1171214
548	ESRRG	P62508	2	0	1	0.247	0.522	1	76.18379	3.288085	up_reg	338	0.1158072
385	MYB	P10242	2	0	1	0.162	0.652	1	59.19859	5.712612	up_reg	9106	0.1152805
779	HLA-DRB5	Q30154	2	206	6	0.385	0.330	0	88.27784	2.841964	up_reg	548	0.1149010
598	TNNC1	P63316	2	0	1	0.394	0.480	1	79.95947	2.859371	up_reg	127	0.1145534
515	PRKCQ	Q04759	2	0	1	0.202	0.549	2	79.85454	2.711625	up_reg	721	0.1145397
721	HLA-DQA1	P01909	2	0	6	0.385	0.380	0	88.71415	4.559819	up_reg	1989	0.1140901
528	ALOX5AP	P20292	7	0	1	0.299	0.534	1	89.60768	2.082130	up_reg	517	0.1138398
892	CDH1	P12830	2	23050	9	0.076	0.224	0	79.89055	4.933467	up_reg	5706	0.1134782
607	NCF1	P14598	2	1234	2	0.241	0.472	1	83.56633	2.397018	up_reg	369	0.1126085
429	ALK	Q9UM73	2	761	2	0.087	0.620	3	67.27647	4.194048	up_reg	14702	0.1124457
579	CXCL1	P09341	2	1755	4	0.207	0.499	1	82.27114	3.026079	up_reg	6221	0.1123390
678	JPH1	Q9HDC5	2	0	1	0.144	0.413	1	66.01235	2.552469	up_reg	27	0.1120124
587	FBP1	P09467	3	1	2	0.373	0.490	1	94.36528	3.028902	up_reg	548	0.1119800
705	SYNGR3	O43761	2	0	1	0.202	0.389	0	80.73087	2.967295	up_reg	15	0.1113448
590	ANXA3	P12429	2	0	1	0.484	0.487	1	96.34132	4.071198	up_reg	190	0.1109648
595	ITGB6	P18564	2	0	1	0.064	0.481	1	83.51907	5.417491	up_reg	168	0.1105181
582	PPARGC1B	Q86YN6	2	0	1	0.075	0.497	1	50.96161	2.110510	up_reg	252	0.1104777
708	FBXL16	Q8N461	31	0	1	0.345	0.386	0	84.45983	4.344689	up_reg	15	0.1101448
588	WNT7A	O00755	2	761	2	0.309	0.489	1	88.75607	9.734620	up_reg	673	0.1092489
734	TNNI1	P19237	2	1141	3	0.252	0.365	0	78.08491	4.029660	up_reg	90	0.1087483
661	STXBP2	Q15833	2	761	2	0.122	0.430	1	90.53373	2.772280	up_reg	160	0.1085032
745	NUDT14	O95848	2	0	1	0.254	0.354	0	94.66943	2.521537	up_reg	7	0.1084086
549	MCM2	P49736	2	0	2	0.139	0.522	3	76.52259	2.384586	up_reg	1556	0.1081400
679	KNSTRN	Q9Y448	2	0	1	0.402	0.413	1	68.64854	2.082946	up_reg	35	0.1080010
826	TTC30A	Q86WT1	55	1	2	0.265	0.280	0	93.50527	2.528791	up_reg	3	0.1065403
600	WNT2	P09544	2	688	2	0.340	0.478	1	88.00264	2.283292	up_reg	612	0.1062725
865	CLDN16	Q9Y5I7	2	23	6	0.140	0.247	0	69.10264	9.609066	up_reg	118	0.1058790
639	DEPDC1	Q5TB30	2	0	1	0.111	0.445	1	61.05036	5.973836	up_reg	91	0.1058246
633	NECTIN4	Q96NY8	2	761	2	0.112	0.450	1	78.89692	6.633982	up_reg	334	0.1048077
583	IL12RB1	P42701	2	0	1	0.192	0.495	1	77.25548	2.276120	up_reg	347	0.1045889
718	LSM4	Q9Y4Z0	2	761	2	0.486	0.382	0	77.63958	2.319798	up_reg	62	0.1042796
706	SLC7A1	P30825	2	1521	3	0.129	0.387	0	81.62643	2.506855	up_reg	219	0.1039294
684	OTUB2	Q96DC9	2	0	1	0.314	0.410	1	94.26903	2.133800	up_reg	43	0.1035979
686	RASSF7	Q02833	2	0	1	0.307	0.409	1	74.57045	3.298786	up_reg	42	0.1035649
775	TONSL	Q96HA7	2	0	3	0.187	0.335	0	76.48871	2.768622	up_reg	54	0.1033695
562	DTL	Q9NZJ0	2	0	1	0.101	0.511	2	63.43932	4.651305	up_reg	625	0.1016171
780	HOXB5	P09067	2	3032	4	0.277	0.330	0	63.73337	5.327041	up_reg	195	0.1015150
604	CD200R1	Q8TD46	2	0	1	0.414	0.475	1	76.65146	2.587670	up_reg	259	0.1012421
646	MYH14	Q7Z406	2	0	1	0.245	0.442	1	74.65097	6.665417	up_reg	115	0.1009246
750	RUNX3	Q13761	2	9057	5	0.403	0.350	0	62.21557	4.881702	up_reg	1560	0.1005386
631	S100A1	P23297	2	1966	2	0.469	0.452	2	82.78688	5.000700	up_reg	521	0.1000235
650	PCDH7	O60245	2	0	1	0.174	0.439	1	76.89920	2.341810	up_reg	114	0.0998628
709	MARS2	Q96GW9	4	0	1	0.093	0.386	0	89.64912	2.313493	up_reg	31	0.0990810
677	GAPDH	P04406	2	8828	5	0.345	0.413	1	98.17071	2.454683	up_reg	8509	0.0983848
737	TYROBP	O43914	2	4887	4	0.285	0.361	0	64.54930	3.691863	up_reg	602	0.0982793
680	OAS3	Q9Y6K5	19	0	2	0.107	0.413	2	86.81560	2.988047	up_reg	199	0.0972965
756	ASF1B	Q9NVP2	2	750	3	0.391	0.346	0	85.64720	5.643420	up_reg	113	0.0970663
538	CGN	Q9P2M7	2	0	1	0.153	0.528	1	70.80985	2.903039	up_reg	1290	0.0968636
599	CD86	P42081	2	4201	4	0.351	0.479	1	79.80962	2.860159	up_reg	12042	0.0968335
671	CTNNA2	P26232	2	0	1	0.082	0.423	1	80.50284	4.876683	up_reg	94	0.0965124
882	RHOV	Q96L33	2	6094	5	0.401	0.233	0	85.68690	3.846255	up_reg	86	0.0961458
632	DOK7	Q18PE1	2	0	1	0.150	0.450	1	66.42315	5.786555	up_reg	193	0.0959161
622	E2F3	O00716	2	761	2	-0.002	0.462	1	61.41248	2.643044	up_reg	789	0.0959141
743	COX7B	P24311	2	0	2	0.404	0.355	0	90.27638	2.360595	up_reg	50	0.0959081
808	E2F1	Q01094	2	10918	7	0.159	0.295	0	63.73504	2.635547	up_reg	5117	0.0952280
626	OAS1	P00973	19	0	2	0.310	0.455	1	84.21378	3.083827	up_reg	681	0.0945161
908	KRT80	Q6KB66	2	0	5	0.411	0.209	0	76.76731	5.731736	up_reg	32	0.0944565
559	EMB	Q6PCB8	2	2277	2	0.381	0.512	1	78.47557	2.398641	up_reg	3502	0.0940230
695	GRHL1	Q9NZI5	33	0	1	0.206	0.399	0	68.95769	3.061285	up_reg	64	0.0929697
614	TFF3	Q07654	2	761	2	0.405	0.466	1	80.13800	2.167937	up_reg	1057	0.0928517
672	PLS1	Q14651	2	0	2	0.067	0.423	1	87.84443	4.693588	up_reg	352	0.0922279
736	GNL3L	Q9NVN8	13	0	1	0.138	0.362	0	72.84667	3.254326	up_reg	26	0.0921929
511	SPN	P16150	2	0	1	0.297	0.552	1	53.31901	2.356560	up_reg	3261	0.0916684
663	FOXP4	Q8IVH2	2	0	1	0.159	0.427	1	59.23848	2.392759	up_reg	143	0.0914734
868	RAD51AP1	Q96B01	2	333	5	0.122	0.242	0	58.79844	4.168726	up_reg	95	0.0910252
644	GRHL2	Q6ISB3	33	0	1	0.092	0.442	1	67.86823	7.179971	up_reg	231	0.0898608
658	MYO5B	Q9ULV0	41	0	1	0.304	0.432	1	75.50398	3.621753	up_reg	185	0.0893882
763	RPL39L	Q96EH5	2	0	1	0.319	0.343	0	94.09941	3.915386	up_reg	19	0.0893830
896	UHRF1	Q96T88	2	16747	6	0.210	0.221	0	81.26714	4.080136	up_reg	696	0.0880184
772	PDLIM1	O00151	2	3755	2	0.426	0.336	0	70.20826	2.021676	up_reg	70	0.0876870
701	MAFB	Q9Y5Q3	2	1384	3	0.207	0.393	0	64.85064	2.002627	up_reg	701	0.0876390
1026	WDR93	Q6P2C0	2	3795	6	0.147	0.041	0	76.99177	2.267609	up_reg	2	0.0869072
999	SFN	P31947	2	73299	6	0.296	0.091	0	93.38504	5.327039	up_reg	2478	0.0859461
683	GNLY	P22749	2	761	2	0.379	0.410	1	78.38773	2.553860	up_reg	401	0.0858975
754	RABIF	P47224	2	0	1	0.330	0.348	0	89.03728	2.438201	up_reg	29	0.0849111
787	CKMT1B	P12532	8	0	1	0.049	0.325	0	90.05943	4.787301	up_reg	16	0.0847771
872	FKBP1C	Q5VVH2	2	0	1	0.363	0.239	0	95.38909	2.614579	up_reg	1	0.0845362
702	OASL	Q15646	2	0	2	0.340	0.392	0	92.28700	5.308283	up_reg	267	0.0842250
722	MZB1	Q8WU39	29	0	1	0.198	0.380	0	84.76435	3.553878	up_reg	69	0.0841868
573	CDKN2A	P42771	2	761	3	0.396	0.503	2	75.59437	8.463693	up_reg	13656	0.0834904
698	DARS2	Q6PI48	23	0	1	0.102	0.394	0	88.75458	2.268401	up_reg	103	0.0834677
694	TACC3	Q9Y6A5	2	727	2	0.259	0.400	1	58.34000	3.743070	up_reg	369	0.0831793
881	H2AC11	P0C0S8	2	0	1	0.416	0.234	0	91.30357	4.077578	up_reg	1	0.0825362
824	PTK6	Q13882	2	5745	4	0.137	0.283	0	89.16695	2.218046	up_reg	248	0.0822616
707	CEP55	Q53EZ4	2	640	2	0.284	0.386	0	82.79305	5.920805	up_reg	274	0.0822077
689	BUB1	O43683	2	1521	3	0.138	0.403	1	64.12427	4.789490	up_reg	1284	0.0821589
900	PRKCZ	Q05513	2	4419	5	0.054	0.219	0	80.53423	2.469978	up_reg	130	0.0819342
676	CDKN3	Q16667	2	0	1	0.472	0.413	1	91.05949	4.403471	up_reg	184	0.0818743
912	CFAP90	A4QMS7	2	0	1	0.256	0.204	0	75.36202	2.657168	up_reg	0	0.0816000
645	MSX1	P28360	2	1056	2	0.339	0.442	1	65.80064	2.501717	up_reg	1214	0.0814092
786	CKMT1A	P12532	8	0	1	0.049	0.325	0	90.05943	6.417662	up_reg	20	0.0814043
883	CLDN1	O95832	2	15884	6	0.392	0.231	0	84.70039	2.942980	up_reg	1280	0.0812329
669	IFIT2	P09913	2	0	1	0.301	0.424	1	88.96310	2.135232	up_reg	254	0.0811520
804	NOL4L	Q96MY1	2	0	1	0.262	0.302	0	62.45976	2.745127	up_reg	11	0.0811367
700	BOP1	Q14137	13	0	1	0.149	0.393	0	80.78432	2.165984	up_reg	120	0.0806511
749	CADM3	Q8N126	2	0	1	0.379	0.350	0	84.61009	2.432258	up_reg	41	0.0803405
648	IKBKE	Q14164	2	123	2	0.192	0.440	1	88.66232	2.971049	up_reg	1238	0.0791392
603	OLR1	P78380	2	0	1	0.388	0.476	1	87.40709	4.414247	up_reg	1066	0.0791054
729	SPC24	Q8NBT2	2	0	1	0.345	0.372	0	91.39337	4.999440	up_reg	79	0.0788554
567	PNP	P00491	46	1	2	0.189	0.507	1	94.05180	2.680894	up_reg	6777	0.0786628
655	CA12	O43570	2	0	1	0.413	0.434	1	88.39335	3.797709	up_reg	388	0.0784112
781	PSMB3	P49720	2	0	1	0.327	0.330	0	97.37889	2.223922	up_reg	28	0.0782523
727	RFXANK	O14593	2	0	1	0.338	0.374	0	79.70517	2.042703	up_reg	87	0.0781341
673	RGS1	Q08116	2	0	1	0.315	0.422	1	81.96646	2.074463	up_reg	310	0.0771832
643	ALOX5	P09917	7	0	1	0.355	0.442	1	97.15666	2.088381	up_reg	521	0.0769170
762	PPP1R16B	Q96T49	2	0	1	0.190	0.344	0	70.84716	2.196990	up_reg	45	0.0764884
766	PRKCI	P41743	2	38	2	0.145	0.340	0	82.48188	2.360984	up_reg	118	0.0764309
748	MISP	Q8IVT2	2	1139	2	0.227	0.353	0	54.69582	5.997961	up_reg	192	0.0752787
830	EPHA1	P21709	2	4697	4	0.216	0.277	0	80.64237	4.441436	up_reg	315	0.0747575
821	CCNE1	P24864	2	4140	5	0.101	0.284	0	79.97658	5.446912	up_reg	1061	0.0741847
716	UBE2T	Q9NPD8	2	0	1	0.273	0.383	0	86.02709	5.344372	up_reg	147	0.0734360
657	CCL5	P13501	2	9296	3	0.141	0.432	1	89.33505	3.279413	up_reg	8493	0.0732623
752	CADM1	Q9BY67	2	1434	3	0.332	0.349	0	81.61015	2.022739	up_reg	579	0.0731482
792	GINS2	Q9Y248	2	0	2	0.258	0.318	0	93.40448	2.817382	up_reg	85	0.0727677
613	CD52	P31358	2	0	1	0.352	0.466	1	68.58155	2.633993	up_reg	1238	0.0727199
858	LRFN4	Q6PJG9	2	761	2	0.222	0.253	0	78.08724	2.052951	up_reg	20	0.0702153
726	CDCA5	Q96FF9	2	0	1	0.258	0.376	0	63.50505	4.692774	up_reg	156	0.0696938
664	TNFRSF4	P43489	2	0	1	0.295	0.427	1	77.22429	2.183879	up_reg	644	0.0675398
791	ZWINT	O95229	2	4	2	0.268	0.320	0	79.45827	3.872467	up_reg	129	0.0669775
714	PTPRJ	Q12913	2	0	1	0.406	0.384	0	78.57151	2.285213	up_reg	229	0.0667990
696	HLA-DRB1	P01911	2	4530	4	0.309	0.398	0	89.12497	3.221560	up_reg	10656	0.0667934
774	LAMTOR2	Q9Y2Q5	2	0	1	0.338	0.335	0	91.48972	2.013323	up_reg	73	0.0652998
765	FCGR3A	P08637	2	622	3	0.351	0.341	0	85.63872	2.760408	up_reg	763	0.0645424
800	GMIP	Q9P107	2	0	1	0.172	0.303	0	70.24573	2.022512	up_reg	34	0.0644506
816	GINS1	Q14691	2	0	2	0.241	0.287	0	93.30269	3.780438	up_reg	67	0.0641162
606	CD38	P28907	2	2701	2	0.290	0.474	1	91.07150	2.603605	up_reg	9643	0.0631845
846	DSG2	Q14126	2	17165	3	0.361	0.262	0	65.83342	2.526737	up_reg	470	0.0611929
806	MELTF	P08582	2	0	1	0.273	0.298	0	89.73721	2.741729	up_reg	38	0.0607234
851	PRICKLE3	O43900	2	0	1	0.183	0.257	0	67.53085	2.181166	up_reg	13	0.0606762
794	EME1	Q96AY2	2	1520	2	0.155	0.315	0	67.90349	2.216719	up_reg	191	0.0606344
785	MFAP5	Q13361	12	0	1	-0.012	0.327	0	65.71101	3.343997	up_reg	81	0.0604613
720	MMP7	P09237	2	2130	3	0.296	0.381	0	87.58781	8.418438	up_reg	3046	0.0603333
782	MYCN	P04198	2	6049	4	0.286	0.329	0	61.81702	2.589804	up_reg	3302	0.0597757
760	ESCO2	Q56NI9	2	0	1	0.462	0.344	0	58.41527	4.684359	up_reg	136	0.0590688
797	TNFSF13B	Q9Y275	2	761	4	0.316	0.307	0	79.05813	2.662063	up_reg	1362	0.0585418
829	TFAP2C	Q92754	2	2279	3	0.181	0.278	0	66.88803	5.774422	up_reg	281	0.0573072
869	FAM181A	Q8N9Y4	2	0	1	0.330	0.241	0	60.50458	8.294660	up_reg	11	0.0567367
688	CCL20	P78556	2	2052	2	0.403	0.405	1	89.38489	5.283080	up_reg	2596	0.0557205
730	DDAH1	O94760	2	0	1	0.378	0.370	0	95.89648	2.198679	up_reg	338	0.0550072
586	FOXP3	Q9BZS1	2	761	2	0.090	0.491	1	58.06645	2.948779	up_reg	21309	0.0549219
958	CLDN7	O95471	2	1242	6	0.254	0.152	0	82.24946	6.596419	up_reg	302	0.0544738
916	SDC1	P18827	2	4415	6	0.400	0.203	0	55.99303	4.335717	up_reg	1549	0.0527575
740	GRB7	Q14451	2	0	1	0.214	0.360	0	78.88878	6.167946	up_reg	309	0.0524346
862	KCNK15	Q9H427	36	0	1	0.042	0.249	0	79.75423	5.076910	up_reg	19	0.0517830
836	OVGP1	Q12889	2	0	2	0.067	0.271	0	70.75963	2.519934	up_reg	105	0.0506303
982	POU5F1	Q01860	2	14481	8	0.257	0.119	0	66.34535	3.740793	up_reg	3858	0.0504231
855	E2F7	Q96AV8	2	1521	3	0.108	0.254	0	51.27249	4.380384	up_reg	224	0.0503707
1009	H2AX	P16104	2	8754	10	0.328	0.078	0	87.32992	2.528322	up_reg	7218	0.0502524
889	CDCA4	Q9BXL8	2	2277	2	0.090	0.228	0	63.80400	2.599588	up_reg	44	0.0499316
842	ST6GALNAC5	Q9BVH7	3	0	1	0.187	0.268	0	82.09840	2.808701	up_reg	36	0.0495636
922	HLA-DQB1	P01920	2	13782	6	0.257	0.200	0	87.11210	4.148044	up_reg	3668	0.0494282
1024	COL26A1	Q96A83	1	8	5	0.004	0.044	0	60.65501	3.863487	up_reg	8	0.0492052
767	JCHAIN	P01591	35	0	1	0.320	0.338	0	87.07085	3.236821	up_reg	219	0.0491086
783	TNFAIP6	P98066	2	1198	2	0.207	0.328	0	82.64910	2.971830	up_reg	536	0.0490182
735	SEMA3A	Q14563	2	3032	2	0.234	0.363	0	84.47667	3.102679	up_reg	1503	0.0488554
732	PIF1	Q9H611	2	0	1	0.062	0.368	0	77.97936	2.843531	up_reg	476	0.0487560
850	SH2D2A	Q9NP31	2	761	2	0.085	0.258	0	62.79150	2.625689	up_reg	92	0.0484631
888	SYNGR2	O43760	50	0	1	0.192	0.229	0	81.66832	2.408663	up_reg	14	0.0483749
642	PI3	P19957	2	58	2	0.417	0.443	1	71.76906	7.675165	up_reg	9625	0.0475344
711	KCNQ1	P51787	2	1520	2	0.165	0.385	0	68.84458	2.709769	up_reg	2537	0.0474271
764	SEMA3F	Q13275	2	0	1	0.253	0.342	0	84.11920	3.717983	up_reg	283	0.0466328
857	STXBP6	Q8NFX7	52	0	1	0.123	0.254	0	87.12139	2.430172	up_reg	31	0.0462810
802	RTN4R	Q9BZR6	2	761	2	0.240	0.303	0	77.06296	2.676907	up_reg	339	0.0457712
863	KRT7	P08729	2	0	4	0.442	0.249	0	75.69421	7.336874	up_reg	692	0.0451941
894	RSPO1	Q2MKA7	37	8	4	0.111	0.221	0	75.36365	3.025055	up_reg	350	0.0448619
947	C4orf48	Q5BLP8	14	0	1	0.365	0.167	0	78.23739	4.028170	up_reg	3	0.0446724
828	SELPLG	Q14242	2	0	1	0.376	0.279	0	51.08547	2.634270	up_reg	66	0.0444860
873	TNFRSF8	P28908	2	526	2	0.196	0.238	0	61.29206	2.047671	up_reg	72	0.0440364
853	FAM167A	Q96KS9	29	0	1	0.247	0.255	0	72.66449	4.356541	up_reg	37	0.0439380
963	ESPN	B1AK53	2	3036	5	0.114	0.144	0	68.30997	7.443990	up_reg	202	0.0432265
905	CDH2	P19022	2	2326	5	0.099	0.215	0	79.17653	2.559787	up_reg	1215	0.0421722
724	RRM2	P31350	2	0	1	0.276	0.377	0	80.12601	5.527053	up_reg	906	0.0420986
784	BCL2A1	Q16548	2	0	1	0.333	0.327	0	87.41244	2.485455	up_reg	273	0.0412050
744	FCGR2B	P31994	2	0	1	0.421	0.355	0	79.03060	2.783225	up_reg	591	0.0401084
877	KRT14	P02533	2	0	4	0.398	0.236	0	75.92890	3.310309	up_reg	716	0.0394507
807	REC8	O95072	2	0	2	0.349	0.297	0	64.69331	3.247582	up_reg	418	0.0390920
875	VGLL1	Q99990	2	0	1	0.305	0.237	0	58.22350	10.261579	up_reg	32	0.0389898
704	CCL2	P13500	2	6612	3	0.274	0.389	0	87.56294	2.248695	up_reg	20922	0.0383422
755	FTH1	P02794	2	0	1	0.354	0.347	0	95.76727	2.083195	up_reg	545	0.0381995
753	CTSS	P25774	2	0	1	0.287	0.348	0	94.54174	2.821640	up_reg	564	0.0380535
860	TNNT1	P13805	2	0	2	0.147	0.251	0	74.97393	6.310523	up_reg	141	0.0379633
934	CCL28	Q9NRJ3	2	7221	4	0.193	0.182	0	73.22394	3.991313	up_reg	357	0.0378979
811	BEND3	Q5T5X7	2	0	1	0.249	0.292	0	65.37982	2.733342	up_reg	142	0.0375846
907	ITGA4	P13612	2	7750	3	0.145	0.211	0	84.56353	2.107446	up_reg	277	0.0375246
805	TP73	O15350	2	892	3	0.199	0.300	0	66.41421	3.196305	up_reg	1569	0.0369809
758	GREM1	O60565	12	0	1	0.032	0.346	0	73.24474	2.646893	up_reg	586	0.0366438
847	IL1B	P01584	2	9795	5	0.104	0.259	0	75.92467	2.915989	up_reg	9812	0.0357108
902	CDC20	Q12834	2	13778	4	0.319	0.217	0	84.85435	6.475074	up_reg	1650	0.0356360
893	MPPED2	Q15777	2	0	1	0.120	0.222	0	95.36715	4.417398	up_reg	28	0.0350523
723	EIF4EBP1	Q13541	2	0	1	0.320	0.379	0	71.29362	2.070414	up_reg	1560	0.0342324
838	COBL	O75128	2	0	1	0.050	0.270	0	50.28154	2.051585	up_reg	103	0.0338677
904	NRTN	Q99748	2	1521	3	0.352	0.216	0	79.04346	5.712851	up_reg	249	0.0334890
924	KRT19	P08727	2	1083	4	0.374	0.199	0	81.40007	3.098124	up_reg	448	0.0334656
831	PPL	O60437	2	7508	3	0.357	0.276	0	75.60075	2.018881	up_reg	2003	0.0316955
837	CD300A	Q9UGN4	2	0	1	0.291	0.270	0	70.96770	2.052455	up_reg	124	0.0309319
849	AIMP2	Q13155	4	0	1	0.116	0.258	0	81.79153	2.483720	up_reg	94	0.0305124
822	KCNQ3	O43525	2	0	2	0.045	0.284	0	57.10836	3.162918	up_reg	527	0.0302013
835	ULBP3	Q9BZM4	2	0	1	0.341	0.273	0	82.87018	4.365563	up_reg	143	0.0298734
871	CABLES1	Q8TDN4	2	0	1	0.107	0.239	0	57.81542	2.363657	up_reg	61	0.0297239
990	KRT16	P08779	2	2509	5	0.333	0.106	0	74.43273	4.141592	up_reg	182	0.0290281
887	HLA-DPB1	P04440	2	0	4	0.168	0.229	0	87.13757	3.113183	up_reg	1195	0.0284837
1006	LRFN1	Q9P244	2	1520	3	0.146	0.082	0	70.58550	3.127358	up_reg	11	0.0283563
832	PSMB9	P28065	2	0	1	0.362	0.276	0	91.17994	2.788039	up_reg	173	0.0280527
854	NACC1	Q96RE7	2	0	1	0.205	0.255	0	64.21521	3.382755	up_reg	102	0.0280219
659	TES	Q9UGI8	2	0	1	0.196	0.431	1	86.49349	2.394874	up_reg	8760	0.0274987
870	LILRB4	Q8NHJ6	2	0	2	0.423	0.240	0	66.70081	3.936863	up_reg	208	0.0273940
809	TACSTD2	P09758	2	0	1	0.332	0.294	0	82.22030	6.975909	up_reg	296	0.0267184
818	SIX1	Q15475	28	2	2	0.184	0.287	0	74.01302	5.368302	up_reg	721	0.0264089
930	PARS2	Q7L3T8	2	0	1	0.407	0.194	0	88.46743	2.174840	up_reg	24	0.0262213
980	TUBB4A	P04350	2	2031	4	0.190	0.124	0	92.24309	3.282229	up_reg	118	0.0258375
944	WWC1	Q8IX03	2	3714	3	0.055	0.175	0	61.50142	5.147188	up_reg	174	0.0255036
942	CHAC2	Q8WUX2	17	0	1	0.084	0.176	0	93.52453	2.630675	up_reg	16	0.0251771
932	SH2B2	O14492	2	0	2	0.200	0.184	0	64.23783	2.606184	up_reg	59	0.0249140
1011	CCNB2	O95067	2	21505	5	0.089	0.073	0	80.38333	4.940087	up_reg	453	0.0248989
880	CDT1	Q9H211	2	761	3	0.393	0.234	0	74.90779	4.825580	up_reg	656	0.0243233
864	BANK1	Q8NDB2	2	0	1	0.100	0.248	0	61.61418	3.730736	up_reg	117	0.0230518
914	ARL11	Q969Q4	2	0	1	0.147	0.203	0	88.13514	3.125100	up_reg	38	0.0227234
931	S100A9	P06702	2	2897	5	0.328	0.187	0	94.90595	2.289678	up_reg	2190	0.0222827
906	NHERF1	O14745	2	1521	3	0.202	0.212	0	72.47472	3.097348	up_reg	466	0.0219151
967	POMK	Q9H5K3	2	761	2	0.236	0.139	0	91.65736	5.585370	up_reg	24	0.0218323
823	CXCL9	Q07325	2	4000	3	0.304	0.283	0	87.92398	5.250589	up_reg	3397	0.0217137
825	S100A2	P29034	2	0	1	0.329	0.282	0	87.05777	5.595045	up_reg	304	0.0214941
799	WNT11	O96014	2	0	1	0.355	0.304	0	90.30817	2.266810	up_reg	623	0.0188681
820	PPP1R1B	Q9UD71	2	0	1	0.401	0.285	0	66.04138	2.849180	up_reg	390	0.0187293
917	HOXB4	P17483	2	0	3	0.094	0.202	0	68.07405	4.785876	up_reg	429	0.0173451
939	PCBD1	P61457	2	0	1	0.378	0.180	0	96.56937	2.014142	up_reg	30	0.0171877
960	GALNT5	Q7Z7M9	2	0	1	0.076	0.151	0	69.18376	3.327325	up_reg	15	0.0161448
919	UQCRFS1	P47985	2	0	1	0.381	0.202	0	81.75593	2.088377	up_reg	57	0.0159885
879	MYCL	P12524	11	0	1	0.386	0.235	0	65.02508	7.726211	up_reg	137	0.0153527
895	TNFAIP2	Q03169	52	0	1	0.238	0.221	0	85.94862	2.993107	up_reg	97	0.0152162
925	PLK4	O00444	2	767	3	0.133	0.199	0	66.92294	2.644551	up_reg	485	0.0151428
997	ISG15	P05161	2	10014	6	0.503	0.095	0	86.54014	4.583876	up_reg	1808	0.0140394
970	COX6B1	P14854	2	13	2	0.393	0.135	0	94.90168	2.489263	up_reg	35	0.0134838
940	DOK5	Q9P104	2	0	1	0.200	0.179	0	78.36019	5.673957	up_reg	38	0.0131234
953	EXOSC4	Q9NPD3	2	0	1	0.335	0.159	0	89.83185	2.636612	up_reg	25	0.0115953
890	MATK	P42679	2	3136	3	0.135	0.225	0	83.78212	2.482567	up_reg	1410	0.0114700
839	SPI1	P17947	2	0	2	0.383	0.269	0	65.99688	2.766086	up_reg	1314	0.0096363
956	NDUFB3	O43676	2	0	1	0.294	0.157	0	86.46141	2.013948	up_reg	28	0.0090523
968	TNFRSF21	O75509	2	2279	3	0.215	0.137	0	69.40738	2.418514	up_reg	172	0.0087063
813	SALL4	Q9UJQ4	2	0	1	0.204	0.290	0	51.44781	3.878009	up_reg	846	0.0083910
918	MAP7	Q14244	2	0	1	0.366	0.202	0	62.54288	3.092922	up_reg	94	0.0081124
945	LRP8	Q14114	2	1520	2	0.423	0.171	0	73.62178	2.246711	up_reg	139	0.0080760
901	EYA4	O95677	28	0	1	0.371	0.218	0	64.03401	3.012436	up_reg	144	0.0077629
959	IFIT3	O14879	2	5526	3	0.158	0.152	0	75.74696	2.375046	up_reg	344	0.0077182
965	COL9A2	Q14055	1	0	3	0.053	0.140	0	55.63427	4.196349	up_reg	167	0.0075462
861	HDGF	P51858	26	0	1	0.359	0.250	0	68.36683	2.071828	up_reg	328	0.0074851
950	CLEC5A	Q9NY25	2	348	2	0.252	0.165	0	85.45138	2.904175	up_reg	115	0.0072232
913	LSP1	P33241	2	563	2	0.145	0.204	0	60.56910	2.311015	up_reg	316	0.0070435
878	NTN1	O95631	2	761	2	0.246	0.236	0	88.71749	3.118007	up_reg	738	0.0065793
793	RIPK3	Q9Y572	2	0	1	0.217	0.318	0	67.61724	2.151159	up_reg	1999	0.0058767
962	PDZK1IP1	Q13113	2	761	2	0.247	0.145	0	65.20753	7.379819	up_reg	81	0.0052724
937	ARL4C	P56559	2	0	1	0.393	0.180	0	93.52089	4.733473	up_reg	65	0.0051260
988	TMEM30B	Q3MIR4	9	0	1	0.223	0.113	0	92.35448	3.021734	up_reg	13	0.0030762
833	MSLN	Q13421	2	0	1	0.171	0.275	0	79.08734	7.267283	up_reg	812	0.0030450
994	SKA1	Q96BD8	2	3740	3	0.218	0.102	0	85.82242	5.476597	up_reg	114	0.0030375
903	PMAIP1	Q13794	2	3032	2	0.317	0.217	0	82.91014	3.896961	up_reg	738	0.0017976
981	ITGB7	P26010	2	2752	2	0.268	0.121	0	82.84386	3.324527	up_reg	73	-0.0002183
1036	SYTL1	Q8IYJ3	2	3037	4	0.036	0.011	0	72.77781	4.342698	up_reg	40	-0.0011060
946	KSR2	Q6VAB6	2	0	1	0.284	0.169	0	61.41177	5.960690	up_reg	79	-0.0023446
928	CKS2	P33552	2	0	1	0.368	0.194	0	92.87122	4.440040	up_reg	168	-0.0042819
1003	FAAP24	Q9BTP7	2	761	2	0.199	0.087	0	90.18733	2.416477	up_reg	35	-0.0047880
991	SH3RF2	Q8TEC5	2	0	1	0.059	0.105	0	57.59249	2.729593	up_reg	18	-0.0049982
995	COX5B	P10606	2	41	3	0.105	0.096	0	85.69271	2.427432	up_reg	136	-0.0067470
844	MUC4	Q99102	2	0	1	0.254	0.266	0	58.53420	3.542323	up_reg	1209	-0.0069021
948	PCLAF	Q15004	2	0	1	0.264	0.167	0	66.12640	5.401491	up_reg	103	-0.0073323
923	SPINT1	O43278	51	0	1	0.107	0.200	0	77.01837	6.141109	up_reg	238	-0.0074136
921	TRIB1	Q96RU8	2	0	1	0.268	0.201	0	77.94675	2.875736	up_reg	271	-0.0090781
898	CD48	P09326	2	761	2	0.445	0.219	0	83.72723	3.054479	up_reg	1312	-0.0093950
941	CXCL11	O14625	2	1773	3	0.353	0.178	0	77.92419	7.143297	up_reg	1585	-0.0108876
843	IL18	Q14116	2	2672	3	0.438	0.267	0	89.07080	3.642493	up_reg	16116	-0.0111817
976	CLIC3	O95833	20	0	1	0.143	0.127	0	94.15899	4.900396	up_reg	48	-0.0113200
929	LTB	Q06643	2	1331	3	0.279	0.194	0	78.39808	5.296640	up_reg	2405	-0.0116882
984	LILRB1	Q8NHL6	2	1319	3	0.177	0.118	0	73.03943	2.334817	up_reg	396	-0.0133436
992	CLU	P10909	2	1521	5	0.158	0.104	0	76.87086	2.491979	up_reg	2364	-0.0138447
742	BID	P55957	2	0	1	0.136	0.357	0	62.45273	2.048675	up_reg	19500	-0.0148731
1017	PPP2R2B	Q00005	2	3032	3	0.106	0.055	0	90.41175	3.664496	up_reg	113	-0.0165017
1028	COL22A1	Q8NFW1	1	0	3	0.106	0.037	0	54.74523	2.383929	up_reg	58	-0.0169511
933	APLP1	P51693	2	0	1	0.120	0.183	0	69.72252	4.237735	up_reg	286	-0.0171349
996	RIPK4	P57078	2	15	2	0.135	0.096	0	74.60517	6.184659	up_reg	100	-0.0185799
886	GRN	P28799	2	761	2	0.140	0.230	0	76.98417	2.143488	up_reg	3094	-0.0186817
1010	ILDR2	Q71H61	2	0	1	0.046	0.075	0	56.53694	2.554303	up_reg	23	-0.0207271
964	RGCC	Q9H4X1	2	0	1	0.314	0.141	0	71.58154	2.366748	up_reg	128	-0.0211708
936	SOX17	Q9H6I2	2	6	2	0.278	0.181	0	59.27884	4.879374	up_reg	1021	-0.0215327
1032	JUP	P14923	2	14648	4	0.091	0.021	0	81.10563	2.578337	up_reg	484	-0.0221315
935	HMGA1	P17096	2	1520	2	0.159	0.181	0	65.46237	6.591907	up_reg	1299	-0.0234943
814	CD4	P01730	2	3035	4	0.442	0.289	0	85.57181	2.281950	up_reg	186553	-0.0243523
1035	C15orf48	Q9C002	2	0	2	0.212	0.018	0	89.84824	5.134800	up_reg	21	-0.0254716
915	DNMT3B	Q9UBC3	2	56	2	0.077	0.203	0	73.57543	2.148336	up_reg	2407	-0.0263504
957	CCL8	P80075	2	0	2	0.258	0.153	0	89.58629	3.845029	up_reg	703	-0.0267906
966	KLK8	O60259	2	0	1	0.329	0.140	0	88.53643	7.914436	up_reg	184	-0.0273257
848	LCN2	P80188	2	0	1	0.140	0.259	0	91.99169	9.042459	up_reg	3659	-0.0273692
993	ESRP2	Q9H6T0	2	0	1	0.052	0.103	0	74.32537	4.950124	up_reg	77	-0.0283405
859	EPCAM	P16422	2	77	2	0.289	0.252	0	87.50649	7.738423	up_reg	9825	-0.0291702
1029	EPS8L1	Q8TE68	2	0	1	0.064	0.026	0	75.61647	5.101489	up_reg	11	-0.0292633
969	CHI3L1	P36222	2	761	3	0.134	0.135	0	94.99146	4.967392	up_reg	1596	-0.0294538
987	FEN1	P39748	2	0	3	0.078	0.113	0	90.03506	2.230667	up_reg	874	-0.0295948
713	HP	P00738	2	0	1	0.249	0.384	0	86.65695	3.617985	up_reg	99196	-0.0300371
1016	COL10A1	Q03692	1	5	4	-0.010	0.058	0	61.49775	4.041689	up_reg	679	-0.0308974
974	RAB25	P57735	41	0	1	0.148	0.130	0	87.08353	7.156164	up_reg	189	-0.0317514
971	FOXQ1	Q9C009	2	0	1	0.151	0.132	0	62.11694	8.570065	up_reg	207	-0.0323961
1031	HOXB7	P09629	2	761	4	-0.001	0.021	0	66.86952	5.290210	up_reg	318	-0.0326778
1004	CHMP4C	Q96CF2	2	0	1	0.263	0.083	0	77.35806	4.735938	up_reg	64	-0.0334303
977	CARD11	Q9BXL7	2	761	2	0.121	0.124	0	72.04895	2.481919	up_reg	557	-0.0337364
1013	ILDR1	Q86SU0	2	0	1	0.115	0.071	0	58.96387	8.292796	up_reg	49	-0.0340425
1002	CDCA7	Q9BWT1	2	0	1	0.158	0.087	0	66.71299	3.825804	up_reg	85	-0.0362989
1025	TGM1	P22735	2	1487	3	0.097	0.042	0	85.13601	2.974339	up_reg	253	-0.0364066
885	CXCL10	P02778	2	0	2	0.109	0.230	0	90.08511	6.235378	up_reg	8876	-0.0364446
1007	CSF2RA	P15509	2	0	1	0.110	0.079	0	82.07854	2.326266	up_reg	117	-0.0445482
1022	RAP1GAP	P47736	2	2277	2	0.060	0.047	0	70.99696	3.713069	up_reg	184	-0.0450333
1037	DUSP23	Q9BVJ7	2	0	1	0.465	0.001	0	97.64673	2.213370	up_reg	17	-0.0457352
972	PITX1	P78337	2	0	1	0.326	0.132	0	63.26645	4.758002	up_reg	479	-0.0457441
978	ESM1	Q9NQ30	2	0	1	0.181	0.124	0	73.14345	3.038808	up_reg	509	-0.0499118
920	IL1RN	P18510	2	0	1	0.197	0.201	0	87.13193	4.132662	up_reg	3592	-0.0502743
1023	SKAP1	Q86WV1	2	0	1	0.224	0.046	0	71.43923	5.275064	up_reg	75	-0.0507258
952	NMU	P48645	2	0	1	0.141	0.161	0	63.72954	8.371797	up_reg	1511	-0.0524586
1021	NKD2	Q969F2	2	0	1	0.151	0.047	0	56.92392	2.149191	up_reg	86	-0.0524835
983	TNF	P01375	2	6688	6	0.273	0.119	0	85.00767	6.265458	up_reg	221351	-0.0572156
1034	MAD2L1	Q13257	2	3785	3	0.178	0.019	0	93.75853	3.426759	up_reg	681	-0.0585201
1015	CCNF	P41002	2	0	1	0.276	0.059	0	72.44700	2.582579	up_reg	183	-0.0596392
1001	CARD9	Q9H257	2	0	1	0.125	0.087	0	81.15426	3.240362	up_reg	539	-0.0656241
1000	HMGA2	P52926	2	761	2	0.202	0.089	0	65.13682	5.165815	up_reg	1858	-0.0669453
998	LYZ	P61626	2	0	1	0.190	0.093	0	94.45464	3.176699	up_reg	688	-0.0671135
1019	SGO1	Q5FBB7	2	0	1	0.108	0.050	0	55.17324	5.338592	up_reg	255	-0.0685104
975	CDKN2B	P42772	2	0	1	0.321	0.128	0	90.76140	2.453778	up_reg	2033	-0.0703923
1008	E2F2	Q14209	2	0	1	0.180	0.079	0	64.08260	5.446447	up_reg	639	-0.0715360
954	BORA	Q6PGQ7	2	0	1	0.259	0.158	0	50.73243	2.025953	up_reg	4796	-0.0720873
1030	DYRK1B	Q9Y463	25	0	1	0.097	0.022	0	74.53225	2.195558	up_reg	164	-0.0726995
909	MET	P08581	2	3305	3	0.093	0.209	0	79.58763	2.695561	up_reg	276508	-0.0789652
1012	SPP1	P10451	2	2257	2	0.312	0.072	0	53.13979	5.389308	up_reg	4958	-0.0875498
1005	GDF15	Q99988	2	0	1	0.062	0.082	0	75.41460	2.195446	up_reg	2514	-0.0921805

Gene subset progression

## Raw gene list = 55660 --> Initial subset (>1 in >=0.5) = 15410

## Initial subset = 15410 --> EdgeR hits (only dif exp genes) = 3257

## EdgeR hits = 3257 --> ensembl gene converted = 3118

## ensembl gene converted = 3118 --> Cytoscape/STRING = 2692

## Cytoscape/STRING = 2692 --> PCSF subnet = 899

## PCSF subnet = 899 --> Druggability CrossRef = 1037

## Druggability CrossRef = 1037 --> Unique IDs = 865

end of doc